Translational Models Of Parkinson S Disease And Related Movement Disorders
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Translational Models Of Parkinson S Disease And Related Movement Disorders
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Author : Wael Mohamed
language : en
Publisher: Elsevier
Release Date : 2024-11-26
Translational Models Of Parkinson S Disease And Related Movement Disorders written by Wael Mohamed and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-26 with Medical categories.
Translational Models of Parkinson's Disease and Related Movement Disorders focuses on cutting-edge techniques for creating and validating current Parkinson's Disease translational experimental models. Various characteristics of these models are examined, including the prion-like properties of -synuclein, mitochondrial functions connected to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway connected to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells). This book also highlights the future possibilities of introducing new models for Parkinson's Disease and related movements disorders, underscoring current advancements, pre-clinical and clinical developments, and future scope related to numerous models. - Highlights induction and validation of different available experimental models of Parkinson's Disease - Provides a comparative prospect of different experimental models of Parkinson's Disease - Discusses the advantages and disadvantages of each model, including associated limitations
Movement Disorders
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Author : Mark S. LeDoux
language : en
Publisher: Elsevier
Release Date : 2014-10-24
Movement Disorders written by Mark S. LeDoux and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-24 with Medical categories.
The use of animal models is a key aspect of scientific research in numerous fields of medicine. Movement Disorders, Second Edition vigorously examines the important contributions and application of animal models to the understanding of human movement disorders, and serves as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. The book is divided into sections on Parkinson's disease, Huntington's disease, dystonia, tremor, paroxysmal movement disorders, ataxia, myoclonus, restless legs syndrome, drug-induced movement disorders, multiple system atrophy, progressive supranuclear palsy/corticobasal degeneration, and spasticity. This book serves as an essential resource for both clinicians interested in the science being generated with animal models and basic scientists studying the pathogenesis of particular movement disorders. - Introduces the scientific foundations for modern movement disorders research - Contributing authors are internationally known experts - Completely revised with 20% new material - Provides a comprehensive discussion of genetics for each type of movement disorder - Covers Parkinson's disease, Huntington's disease, dystonia, tremors, and tics
Insights In Parkinson S Disease And Aging Related Movement Disorders 2022
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Author : Robert Petersen
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-16
Insights In Parkinson S Disease And Aging Related Movement Disorders 2022 written by Robert Petersen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-16 with Science categories.
Given the success of the previous edition of this Research Topic and the rapidly evolving subject area, we are pleased to announce the 2022 edition, which aims to give continuity on the subject and highlight state-of-the-art research. We are now entering the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists have been exceptional, leading to major advancements in the fast-growing field of Parkinson’s Disease and Aging-related Movement Disorders. Frontiers has organized a series of Research Topics to highlight the latest advancements across the field of Aging Neuroscience, with articles from the Associate Members of our accomplished Editorial Boards. This editorial initiative of particular relevance, led by Dr. Robert Petersen, Specialty Chief Editor of the Parkinson’s Disease and Aging-related Movement Disorders section, is focused on new insights, novel developments, current challenges, latest discoveries, recent advances, and future perspectives in Parkinson’s Disease and Aging-related Movement Disorders.
The Neuroscience Of Feelings Brain Heart Connectivity In Neurodegenerative Diseases
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Author :
language : en
Publisher: Academic Press
Release Date : 2025-07-01
The Neuroscience Of Feelings Brain Heart Connectivity In Neurodegenerative Diseases written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-01 with Psychology categories.
The Neuroscience of Feelings: Brain-Heart Connectivity in Neurodegenerative Diseases, Volume 294 explores the complex interplay between emotions and brain function+G147, covering topics such as The role of heart-brain connectivity in neurodegeneration: mechanisms and impacts, Cardiovascular influence on cognitive decline: the heart's role in neurodegenerative disorders, Autonomic nervous system dysregulation in neurodegenerative diseases: bridging brain and heart, Heart rate variability as an indicator of brain health in neurodegeneration, and much more.Other sections cover Emotional stress and cardiovascular health: impacts on neurodegenerative disease progression, Exploring heart-brain axis alterations in Parkinson's disease, Cardiac biomarkers as predictors of cognitive decline in neurodegenerative conditions, Heart-brain synchrony: therapeutic implications for neurodegenerative disease, and Neurocardiology and neurodegenerative diseases: emerging research on emotional regulation and brain-heart connectivity. - Bridges neuroscience and cardiology, providing a holistic view of how heart-brain interactions influence neurodegenerative diseases - Features the latest studies on autonomic nervous system dysregulation, cardiac biomarkers, and emotional stress - Explores novel diagnostic tools and interventions for cognitive decline and neurodegenerative disorders
Translational Advances In Alzheimer S Parkinson S And Other Dementia Molecular Mechanisms Biomarkers Diagnosis And Therapies Volume Ii
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Author : Jiehui Jiang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-15
Translational Advances In Alzheimer S Parkinson S And Other Dementia Molecular Mechanisms Biomarkers Diagnosis And Therapies Volume Ii written by Jiehui Jiang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-15 with Science categories.
Reproducibility And Replicability In Parkinson S Disease And Age Related Movement Disorders
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Author : Vinita Ganesh Chittoor
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-13
Reproducibility And Replicability In Parkinson S Disease And Age Related Movement Disorders written by Vinita Ganesh Chittoor and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-13 with Medical categories.
Advances In Neuromodulation Treatment Of Parkinson S Disease And Aging Related Movement Disorders
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Author : Kailiang Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2024-04-22
Advances In Neuromodulation Treatment Of Parkinson S Disease And Aging Related Movement Disorders written by Kailiang Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-22 with Science categories.
Parkinson's disease (PD) is an age-related neurodegenerative disorder characterized by progressive motor disability with a spectrum of non-motor symptoms. Similar to Parkinson's disease, essential tremor, dystonia, Huntington's disease, and other aging-related movement disorders are widespread in the elderly with relatively unideal medicine-treatment effects. In recent years, deep brain stimulation (DBS) has been established as an effective treatment for PD and other aging-related movement disorders, especially with motor symptoms. However, there are still many problems to be solved in research work and clinical practice in this field. For example, it is unclear regarding the most effective stimulation targets or the underlying mechanism of DBS. And it is still unknown how to choose the optimal targets among STN, GPi, PSA, VIM, etc, or if we could choose the nerve fiber for stimulation besides the nuclei, And despite wearable sensors could be a powerful tool for the digital evaluation of movement disorders or provide the feedback biomarkers for DBS, the closed-loop biomarkers for DBS are still lacking. Furthermore, apart from PD, the DBS treatment in gene-related dystonia, Huntington's disease, and other movement disorders also needs to be further explored.
Zebrafish As A Model For Parkinson S Disease
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Author : Wael Mohamed
language : en
Publisher: CRC Press
Release Date : 2024-10-04
Zebrafish As A Model For Parkinson S Disease written by Wael Mohamed and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-04 with Science categories.
The increasing demand for innovative techniques arises from the lack of safe, effective, and patient-friendly therapies for neurodegenerative disorders. With this objective in mind, the chapters of the book are structured to offer a thorough insight into recent advancements in utilizing the zebrafish (ZF) as a model for studying Parkinson’s disease (PD). This book aims to present readers with a comprehensive understanding of the clinical application of the ZF model in treating PD, encompassing the latest developments, challenges, safety considerations, toxicity issues, regulatory aspects, future potential, and limitations. Individuals in academia, the scientific community, business, and education seeking a more effective approach to target the brain stand to benefit from this resource. Key Features Provides a comparative perspective of the zebrafish–Parkinson’s disease model Highlights the restrictions of available medicines Describes biochemical and histopathological characteristics, advantages, and disadvantages of this model Emphasizes distinct facets of histopathology Presents advances and developments of the future potential perspectives
Neuropsychiatric And Cognitive Changes In Parkinson S Disease And Related Movement Disorders
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Author : Dag Aarsland
language : en
Publisher: Cambridge University Press
Release Date : 2013-08-29
Neuropsychiatric And Cognitive Changes In Parkinson S Disease And Related Movement Disorders written by Dag Aarsland and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-29 with Medical categories.
A broad and in-depth discussion of the important, but still uninformed, field of behavioral disturbances associated with Parkinson's disease.
Modeling Parkinson S Disease Bridging The Translational Gap
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Author : Graziella Madeo
language : en
Publisher: Frontiers Media SA
Release Date : 2019-11-26
Modeling Parkinson S Disease Bridging The Translational Gap written by Graziella Madeo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-26 with categories.