Translational Neuroimaging
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Translational Neuroimaging
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Author : Robert A. McArthur
language : en
Publisher: Academic Press
Release Date : 2012-10-26
Translational Neuroimaging written by Robert A. McArthur and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-26 with Medical categories.
This book covers methodical issues in human and animal neuroimaging translational research as well as detailed applied examples of the use of neuroimaging in neuropsychiatric disorders and the development of drugs for their treatment. Offering an accompanying website with illustrations and text available for further knowledge and presentations, Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment appeals to non-clinical and clinical neuroscientists working in and studying neuropsychiatric disorders and their treatment as well as providing the novice researcher or researcher outside of his/her expertise the opportunity to understand the background of translational research and the use of imaging in this field. Provides a background to translational research and the use of brain imaging in neuropsychiatric disorders.
Progress In Translational Neuroimaging Integrating Pathways Systems And Phenomenology In Neurology And Psychiatry
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Author : Drozdstoy Stoyanov
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-21
Progress In Translational Neuroimaging Integrating Pathways Systems And Phenomenology In Neurology And Psychiatry written by Drozdstoy Stoyanov and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-21 with categories.
Translational Applications Of Neuroimaging
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Author : Stavros Skouras
language : en
Publisher: Frontiers Media SA
Release Date : 2024-04-04
Translational Applications Of Neuroimaging written by Stavros Skouras and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-04 with Science categories.
Despite substantial progress in the development of neuroimaging methodologies, translational applications of neuroimaging remain scarce. This Research Topic invites article submissions that present promising neuroimaging applications and methods addressing critical needs for improving health outcomes. These may include Original Research, Clinical Trial, Systematic Review or Methods articles that investigate neuroimaging metrics as outcome measures or in combination with neural perturbation techniques (e.g., neurofeedback, neurostimulation), other translational applications (e.g., guiding neurosurgery). To foster debate, we also welcome critical Review, Opinion, and Perspective articles that survey the field and its progress towards clinical utility.
Translational Neuroimaging
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Author : Robert A. McArthur
language : en
Publisher: Academic Press
Release Date : 2012-10-05
Translational Neuroimaging written by Robert A. McArthur and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-05 with Medical categories.
Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment combines the experience of academic, clinical and industrial neuroimagers in a unique collaborative approach to provide an integrated perspective of the use of small animal and human brain imaging in developing and validating translational models and biomarkers for the study and treatment of neuropsychiatric disorders. Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment examines the translational role of neuroimaging in model development from preclinical animal models, to human experimental medicine, and finally to clinical studies. The focus of this book is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This book covers methodical issues in human and animal neuroimaging translational research as well as detailed applied examples of the use of neuroimaging in neuropsychiatric disorders and the development of drugs for their treatment. Offering an accompanying website with illustrations and text available for further knowledge and presentations, Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment appeals to non-clinical and clinical neuroscientists working in and studying neuropsychiatric disorders and their treatment as well as providing the novice researcher or researcher outside of his/her expertise the opportunity to understand the background of translational research and the use of imaging in this field. Provides a background to translational research and the use of brain imaging in neuropsychiatric disorders Critical discussion of the potential and limitations of neuroimaging as a translational tool for identifying and validating biomarkers Identifies cross species neurosystems and common endpoints necessary to help accelerate CNS drug discovery and development for the treatment of neuropsychiatric disorders Features an accompanying website with additional images and text
Functional Magnetic Resonance Imaging Fmri
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Author : Lori A. Whitten
language : en
Publisher: RTI Press
Release Date : 2012-12-11
Functional Magnetic Resonance Imaging Fmri written by Lori A. Whitten and has been published by RTI Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-11 with Medical categories.
The sophisticated methods of neuroscience—including molecular genetics, structural and functional neuroimaging, animal models, and experimental tasks that approximate real-world behaviors in human research—have yielded important insights about typical functioning and neurobehavioral disorders. Translational neuroscience endeavors to use this knowledge to improve the human condition by developing and improving interventions for these disorders. This paper reviews the literature on the contribution of functional magnetic resonance imaging (fMRI) and two related techniques, resting-state fMRI (rs-fMRI) and real-time fMRI (rt-fMRI), to the diagnosis and treatment of behavioral problems and psychiatric disorders. It also explains how incorporating neuroscience principles and techniques into research on the prevention of substance misuse and antisocial behavior may spur advances and innovations in this important area. This article argues that fMRI’s potential contribution to these prevention efforts has yet to be fully realized, explores new ways in which the technique could be adapted to that end, highlights some of the work by researchers in the vanguard of this effort, and notes limitations of fMRI and ethical concerns the technique raises.
Translational Neurosonology
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Author : A. Alonso
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2014-12-16
Translational Neurosonology written by A. Alonso and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-16 with Medical categories.
Diagnostic ultrasound has become an elementary tool for evaluating cerebrovascular diseases and plays a prominent role in routine clinical practice. Many publications attempt to cover the continuous progress of its diagnostic and even therapeutic applications. However, the impact ultrasound has made in recent years in the fields of animal studies and human research is less well known. This publication provides an overview on exciting current attempts in neurological diseases, ranging from experimental approaches to established imaging modes ready to be incorporated into the routine of daily practice. The first part of the book concentrates on basic principles of neurosonology and focuses on contrast imaging, specific ultrasound contrast agents and safety aspects. The following chapters deal with different vascular ultrasound applications, allowing an optimized characterization of atherosclerotic disease and monitoring of cerebral autoregulation. In addition, the role of parenchymal ultrasound imaging in cerebrovascular diseases and movement disorders is illustrated. The final chapters look at promising new therapeutic approaches implementing ultrasound although they are still no more than experimental. The book can be highly recommended to clinical neurologists with good knowledge in clinical ultrasound who wish to gain a compact and updated insight into the plethora of capabilities of neurosonology in the future.
Magnetic Resonance Neuroimaging
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Author : Michel Modo
language : en
Publisher: Humana Press
Release Date : 2016-08-23
Magnetic Resonance Neuroimaging written by Michel Modo and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Medical categories.
The advent of non-invasive imaging technology, such as magnetic resonance imaging (MRI), has allowed biologists and clinicians to make great strides in unraveling the secrets of the brain. In Magnetic Resonance Neuroimaging: Methods and Protocols, expert researchers in the field provide a comprehensive collection of experimental MRI protocols that can be used to non-invasively interrogate the healthy and diseased brain. The chapters are divided into general techniques, such as the measurement of relaxivity, magnetic resonance spectroscopy, diffusion tensor imaging, and MR reporter genes, as well as specific applications in brain imaging, for example, phenotyping transgenic animals, detecting amyloid plaques, and fMRI in psychiatry. As a volume in the highly successful Methods in Molecular BiologyTM series, this work contains the type of detailed description and implementation advice that is crucial for getting optimal results. Thorough and cutting-edge, Magnetic Resonance Neuroimaging: Methods and Protocols serves neuroscientists, clinical neurologists, psychiatrists, and radiologists with an excellent compendium of methods easily applied to both animal and human studies and certain to be an excellent resource for translational research.
Multimodal Neuroimaging Computing For The Characterization Of Neurodegenerative Disorders
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Author : Sidong Liu
language : en
Publisher: Springer
Release Date : 2017-01-11
Multimodal Neuroimaging Computing For The Characterization Of Neurodegenerative Disorders written by Sidong Liu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-11 with Computers categories.
This thesis covers various facets of brain image computing methods and illustrates the scientific understanding of neurodegenerative disorders based on four general aspects of multimodal neuroimaging computing: neuroimaging data pre-processing, brain feature modeling, pathological pattern analysis, and translational model development. It demonstrates how multimodal neuroimaging computing techniques can be integrated and applied to neurodegenerative disease research and management, highlighting relevant examples and case studies. Readers will also discover a number of interesting extension topics in longitudinal neuroimaging studies, subject-centered analysis, and the brain connectome. As such, the book will benefit all health informatics postgraduates, neuroscience researchers, neurology and psychiatry practitioners, and policymakers who are interested in medical image computing and computer-assisted interventions. “br>
Translational Neuropsychopharmacology
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Author : Trevor W. Robbins
language : en
Publisher: Springer
Release Date : 2016-09-22
Translational Neuropsychopharmacology written by Trevor W. Robbins and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-22 with Medical categories.
This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine.
Human And Animal Models For Translational Research On Neurodegeneration Challenges And Opportunities From South America
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Author : Agustín Ibáñez
language : en
Publisher: Frontiers Media SA
Release Date : 2018-06-21
Human And Animal Models For Translational Research On Neurodegeneration Challenges And Opportunities From South America written by Agustín Ibáñez and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-21 with categories.
Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and developments for future investigation. We present research focused on neurodegenerative research in South America. We introduce studies assessing the interplay among genetic, neural, and behavioral dimensions of these diseases, as well as articles on vulnerability factors, comparisons of findings from various countries, and works promoting multicenter and collaborative networking. More generally, our book covers a broad scope of human-research approaches (behavioral assessment, neuroimaging, electromagnetic techniques, brain connectivity, peripheral measures), animal methodologies (genetics, epigenetics, proteomics, metabolomics, other molecular biology tools), species (all human and non-human animals, sporadic, and genetic versions), and article types (original research, review, and opinion papers). Through this wide-ranging proposal, we hope to introduce a fresh approach to the challenges and opportunities of research on neurodegeneration in South America.