Translational Neuroimmunology In Multiple Sclerosis


Translational Neuroimmunology In Multiple Sclerosis
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Translational Neuroimmunology In Multiple Sclerosis


Translational Neuroimmunology In Multiple Sclerosis
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Author : Ruth Arnon
language : en
Publisher: Academic Press
Release Date : 2016-05-10

Translational Neuroimmunology In Multiple Sclerosis written by Ruth Arnon and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-10 with Science categories.


Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon—such as neuroprotective strategies, stem cells, and repair promotion—are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development. Provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis and the translation of this research to immunotherapy treatment Edited by renowned leaders in the field of neuroimmunology and multiple sclerosis Contains the latest resource material for basic and clinical scientists and practitioners in neuroscience, neurology, immunology, and pharmacology



Translational Neuroimmunology Volume 8


Translational Neuroimmunology Volume 8
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Author : Nima Rezaei
language : en
Publisher: Elsevier
Release Date : 2023-06-16

Translational Neuroimmunology Volume 8 written by Nima Rezaei and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-16 with Medical categories.


Translational Neuroimmunology: Multiple Sclerosis provides an update on bench to bedside studies on Multiple Sclerosis as an autoimmune disease. Divided into twelve chapters, the book begins with an in-depth introduction to the neuroimmunology and immunopathology of multiple sclerosis. Sections also provide content on genetics and epigenetics, the microbiome, diagnosis, and treatment of multiple sclerosis. Finally, various precision treatments are covered. All information is presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research. Provides an introduction on multiple sclerosis as an autoimmune disease, from bench to bedside Encourages the development of immunologic approaches to analyze the interaction and specific properties of nervous tissue elements during development and disease Focuses on understanding and therapeutically manipulating immunological responses to injury, degeneration and autoimmunity in the central nervous system Shows the changes in relevant immune and inflammatory reactions at the cellular and molecular level during the development of nervous system diseases



Translational Neuroimmunology Volume 7


Translational Neuroimmunology Volume 7
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Author : Nima Rezaei
language : en
Publisher: Elsevier
Release Date : 2023-06-16

Translational Neuroimmunology Volume 7 written by Nima Rezaei and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-16 with Medical categories.


Translational NeuroImmunology: Neuroinflammation updates on bench to bedside studies on neurological disorders that have immunological etiologies. The book covers neuroimmunology and the principles of autoimmune and autoinflammatory neurological disorders, with multiple sclerosis as the main focus. The immunopathology, genetics and epigenetics, microbiome, diagnosis and treatment of multiple sclerosis will be explained in ten chapters. A chapter also examines distinct aspects of pericytes, with final discussions on the neurologic manifestations, diagnostic approaches and treatments of the various neuroimmune disorders and lessons learned from translational research on non-human primates and zebrafish. All sections are presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research. Gives an introduction on neuroimmunological diseases, from bench to bedside Encourages the development of immunologic approaches to analyze the interaction and specific properties of nervous tissue elements during development and disease Focuses on understanding and therapeutically manipulating immunological responses to injury, degeneration and autoimmunity in the central nervous system Proves changes in relevant immune and inflammatory reactions at the cellular and molecular level during the development of nervous system diseases



Update On Translational Neuroimmunology Research Of Isni 2018


Update On Translational Neuroimmunology Research Of Isni 2018
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Author : Sandra Amor
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-29

Update On Translational Neuroimmunology Research Of Isni 2018 written by Sandra Amor and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-29 with Medical categories.


The 14th International Congress of Neuroimmunology, ISNI 2018, was held in August 2018 in Brisbane, Australia, and is a biennial event organized by the International Society of Neuroimmunology (ISNI). The theme of ISNI 2018 was “Travelling the Neuroimmunological Translational Highway”, and the Congress highlighted many research discoveries that bridge the gap between basic and clinical sciences, and which impact our understanding of pathogenic immune-mediated mechanisms in diseases affecting the nervous system. In this Research Topic, we aim to give a comprehensive overview of topics highlighted at the Congress, showcasing the current state of the field of neuroimmunology and where it is going in the near future.



Translational Methods For Multiple Sclerosis Research


Translational Methods For Multiple Sclerosis Research
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Author : Sergiu Groppa
language : en
Publisher: Humana
Release Date : 2021-08-03

Translational Methods For Multiple Sclerosis Research written by Sergiu Groppa and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-03 with Medical categories.


This volume explores the recent advances in the study of translational paths in central inflammation and focuses on ongoing pathophysiological processes and the transition between inflammatory stages and progressive states with neurodegeneration. Chapters cover topics such as pathophysiological hallmarks of neuroinflammation from tissue damage to reorganization; connecting studies of mouse models; and investigations of humans with multiple sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Translational Methods for Multiple Sclerosis Research is a valuable resource for researchers who want to learn more about this chronic ad progressive disease, and pave the way for new advancements.



Neuroimmunology


Neuroimmunology
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Author : Amanda L. Piquet
language : en
Publisher: Springer Nature
Release Date : 2021-03-08

Neuroimmunology written by Amanda L. Piquet and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-08 with Medical categories.


This book provides a clinical focus on neuroinflammatory diseases as well as a review in pathophysiology and treatment approaches. Organized into six parts, the book begins with a basic review of the immune system and concepts for learning and treating neuroimmune conditions. The next four sections cover specific subfields of neuroimmunology and autoimmune neurology - the clinical and diagnostic features of multiple sclerosis, other autoimmune conditions of the central nervous system, autoimmune conditions of the peripheral nervous system, and systemic autoimmune conditions that affect the nervous system. To conclude, Section six discusses various clinical approaches to specific presentations in neuroimmunology, including pediatric demyelinating diseases. These sections provide practical clinical information to improve the reader’s knowledge in this complex field. The chapters are written by world renown authors with extensive knowledge to help provide up to date information. The full scope of autoimmune neurology is discussed, which is a unique feature of this book. Neuroimmunology serves as a resource for those in training including residents and fellows to provide clear clinical reasoning and background in a rapidly advancing field.



Clinical Neuroimmunology


Clinical Neuroimmunology
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Author : Syed A. Rizvi
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-09-03

Clinical Neuroimmunology written by Syed A. Rizvi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-03 with Medical categories.


Clinical Neuroimmunology: Multiple Sclerosis and Related Disorders serves as an indispensable resource for physicians interested in, and dealing with, this very complex and evolving branch of neurology. This comprehensive title provides an introduction to basic neuroimmunology and principles of immunotherapy and also serves as a thorough guide to immune-mediated disorders of the central and peripheral nervous system, as well as other systemic disorders with a significant neuroimmunologic component. The chapters are written by experts in their fields and include the most up to date scientific information. This volume is made to simplify complex immunological mechanisms and to focus on practical patient-related issues. Clinical Neuroimmunology: Multiple Sclerosis and Related Disorders is an invaluable addition to the literature and will be of significant interest to neurologists, residents and fellows, internists, and general practitioners who treat patients with neurologic disorders and other systemic autoimmune diseases.



Clinical Neuroimmunology


Clinical Neuroimmunology
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Author : Jack P. Antel
language : en
Publisher:
Release Date : 2005

Clinical Neuroimmunology written by Jack P. Antel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.


Clinical Neurimmunology is the major reference text in the field, providing broad and comprehensive coverage of the interaction between the nervous and immune systems in both normal and diseased states. Understanding this interaction is fundamental to developing therapeutic approaches todisease and injury of the nervous system that are currently only marginally amenable to therapy. Neuroimmunology is a well-recognised and growing specialty world wide, both at the basic science and clinical level. It is a fast moving field and this is the most up to date text available. Chaptersare dedicated to the role of the immune system in disorders affecting both the central and peripheral nervous systems, including important neurodegenerative diseases (such as multiple sclerosis and HIV-related neural degeneration) which cause life-long disability. Extensive coverage is given to awhole array of immune-directed therapies.The book has a strong international team of well respected, high profile editors and authors. The first edition published to extensive and positive reviews and has established itself as the principal reference source in the field. This second edition summarizes recent advances in clinicalneuroimmunology in a comprehensive and unbiased way.



Molecular Basis Of Multiple Sclerosis


Molecular Basis Of Multiple Sclerosis
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Author : Roland Martin
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-14

Molecular Basis Of Multiple Sclerosis written by Roland Martin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-14 with Medical categories.


Despite major efforts by the scientific community over the years, our understanding of the pathogenesis or the mechanisms of injury of multiple sclerosis is still limited. Consequently, the current strategies for treatment and management of patients are limited in their efficacy. The mechanisms of tissue protection and repair are probably even less understood. One reason for these limitations is the enormous complexity of the disease and every facet of its pathogenesis, the mechanisms of tissue injury, the diagnostic procedures and finally the efficacy of treatments and their side effects. The aim of this book is to review the most recent advances made in this highly complex field.



Mechanisms Of Disease Pathogenesis In Multiple Sclerosis


Mechanisms Of Disease Pathogenesis In Multiple Sclerosis
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Author : Francisco Javier Quintana
language : en
Publisher: Academic Press
Release Date : 2023-09-01

Mechanisms Of Disease Pathogenesis In Multiple Sclerosis written by Francisco Javier Quintana and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-01 with Medical categories.


Mechanisms of Disease Pathogenesis in Multiple Sclerosis summarizes our current understanding on MS and its clinical features and monitoring with available biomarkers, focusing on mechanisms that drive disease pathogenesis and their control by genetic, environmental factors and novel therapies for disease management. The book is written for neurologists, neuroimmunologists and clinical, translational and basic researchers interested in mechanisms of neurodegeneration. Multiple Sclerosis (MS) is an autoimmune disease which targets the central nervous system (CNS). It is the most common cause of non-traumatic neurological disability in young adults with a prevalence of 1 in 1000 and increasing, hence the importance of this book.