Tratamiento De La Epilepsia En Situaciones Especiales
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Tratamiento De La Epilepsia En Situaciones Especiales
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Author : César Viteri Torres
language : es
Publisher:
Release Date : 2004
Tratamiento De La Epilepsia En Situaciones Especiales written by César Viteri Torres and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.
Tratamiento De Las Epilepsias
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Author : Roberto Horacio Caraballo
language : es
Publisher: Ed. Médica Panamericana
Release Date : 2009
Tratamiento De Las Epilepsias written by Roberto Horacio Caraballo and has been published by Ed. Médica Panamericana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Cerca del 1% de la población general padece epilepsia; en alrededor del 80% de los pacientes las crisis pueden controlarse de manera eficaz con fármacos antiepilépticos y en el 60% de estos casos las convulsiones remiten definitivamente. Este libro analiza en detalle las características farmacocinéticas y farmacodinámicas, las indicaciones, el uso clínico, las dosis y los efectos adversos de cada antiepiléptico. Hace especial énfasis en el reconocimiento de los diferentes síndromes epilépticos de manera de poder seleccionar la terapéutica en función de la identificación precisa de cada uno de ellos. Describe el análisis terapéutico de diversos grupos de pacientes particulares como los recién nacidos, las personas de tercera edad, las embarazadas y los enfermos en situaciones especiales. En el apéndice se describen las carácterísticas más destacadas de los antiepilépticos de uso cotidiano.
New Antiepileptic Drugs
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Author : Francesco Pisani
language : en
Publisher: Elsevier Publishing Company
Release Date : 1991
New Antiepileptic Drugs written by Francesco Pisani and has been published by Elsevier Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.
The pharmacological fight against epilepsy began many centuries ago when Hippocrates discovered that the cause of epilepsy is natural, as opposed to supernatural and, as a consequence, must be treated with a natural remedy. Even though science has significantly progressed since that era, the challenge to find remedies for epilepsy is ever present. The aim of this particular volume is to offer an up-to-date review of the most recent advances in antiepileptic drug development, considered from various viewpoints: (i) general, by taking into account the size of refractory epilepsy and its related problems; (ii) experimental, by exploring the mechanisms of epileptogenesis and the possiblility of influencing it through drugs, and (iii) clinical, by describing the results obtained with compounds currently at an advanced stage of testing.
Factores Pron Sticos De Refractariedad A Tratamiento M Dico En La Epilepsia Del L Bulo Temporal
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Author : Pedro Jesús Serrano Castro
language : es
Publisher: Universidad Almería
Release Date : 2012-02-15
Factores Pron Sticos De Refractariedad A Tratamiento M Dico En La Epilepsia Del L Bulo Temporal written by Pedro Jesús Serrano Castro and has been published by Universidad Almería this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-15 with Medical categories.
Entre un 20 y un 40% de todas las Epilepsias del Lóbulo Temporal (ELT) se comportan como Epilepsias Refractarias a tratamiento médico (ER) [Cockerell et al, 1997; Kwan & Sander, 2004], según la definición de la Liga Internacional Contra la Epilepsia [Kwan et al, 2010]. Estos enfermos son subsidiarios de alternativas terapéuticas no farmacológicas como la cirugía de la epilepsia, que ha demostrado su capacidad para conseguir la remisión completa de las crisis en un porcentaje considerable de estos casos [Spencer & Hugh, 2008]. La demora de la cirugía tiene un efecto deletéreo en la calidad de vida del enfermo epiléptico. Sin embargo, actualmente, los enfermos que acceder a recursos quirúrgicos, no lo hacen antes de los 20 años de media evolución de su enfermedad [Engel et al. 2003]. En buena parte eso es debido a que no existe en la actualidad un instrumento capaz de adelantar con fiabilidad el diagnóstico de refractariedad antes de los dos años establecidos en la definición operativa de ER en función de las características clínicas y paraclínicas de los pacientes. OBJETIVOS: 1.- Describir las características clínicas y paraclínicas de la ELT del adulto en nuestro medio. 2.- Describir las variables clínicas y paraclínicas asociadas con refractariedad en la ELT del adulto y realizar una estimación del riesgo. 3.- Establecer y validar un modelo de predicción de refractariedad basado en datos semiológicos y de pruebas complementarias. DISEÑO DEL ESTUDIO: Parte 1.- Estudio descriptivo de la cohorte de ELT del adulto. Diseñado para dar respuesta al Objetivo 1. Parte 2.- Estudio retrospectivo caso-control anidado en una cohorte sobre factores predictores de refractariedad en ELT del adulto. Diseñado para responder a los Objetivos 2 y 3. VARIABLES: Variable dependiente: Refractariedad a tratamientos médicos según la definición de la ILAE [Kwan et al, 2010] Variables independientes: 16 variables independientes (predictoras) que se dividen en 11 variables clínicas y 5 variables de pruebas complementarias. CONCLUSIONES: " La ELT es un grupo heterogéneo de epilepsias que comparte la misma zona epileptogénica, pero que son diferentes en edad de debut, etiología, neurofisiología, neuropsicología y respuesta terapéutica. " El subgrupo etiológico de Epilepsias Mediales de LT con Esclerosis Hipocampal (EMLT-EH) tiene una edad de debut precoz, se asocia con el antecedente de convulsiones febriles (CF), y su frecuencia relativa depende del tiempo de evolución. Estos datos clínicos apoyan la idea de que sea consecuencia de un proceso fisiopatológico progresivo. " El subgrupo de ELT de causa desconocida incluye a pacientes pertenecientes a los otros dos subgrupos pero en los que las técnicas de neuroimagen no han sido capaces de identificar la lesión estructural. " El subgrupo de ELT de origen estructural está integrado fundamentalmente por Tumores de estirpe glial, Trastornos del desarrollo cortical, Malformaciones Vasculares y Áreas de encefalomalacia isquémica o postraumática. " La expresión clínica predominante en más del 90% de pacientes con ELT son las Crisis tipo I.B. en la clasificación de la ILAE. " 3/4 de los pacientes presentan conducta motora automática durante las crisis. Este porcentaje tendió a ser mayor en el subgrupo de EMTL-EH. " Casi dos tercios de los pacientes con ELT presentan algún tipo de anomalía en el EEG intercrítico. " La ELT acarrea una importante afectación neuropsicológica. Los pacientes con ELT izquierda o bilateral presentan tanto afectación de memoria verbal como visual de los test de fluencia, mientas que los pacientes con ELT derecha tienen tendencia a preservar las habilidades lingüísticas, tanto de memoria como de fluencia. " Existen 14 variables clínicas y de pruebas complementarias asociadas significativamente al desarrollo de refractariedad y 1 que actúa como factor protector. 5 Variables son independientes para el desarrollo de refractariedad: Presencia de automatismos de cualquier clase, RM patológica y EEG interictal seriado patológico, necesidad de más de 3 FAE y necesidad de cirugía. " Es posible establecer un modelo de predicción clínica de evolución a refractariedad. " La presencia de automatismos durante las crisis asociado a una anomalía estructura en RM con protocolo específico de epilepsia y a una alteración focal en EEGs intercríticos seriados se asocia con una probabilidad cercana al 85% al desarrollo de refractariedad asumiendo una prevalencia pretest del 50%.
Epilepsy And Pregnancy
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Author : Torbjörn Tomson
language : en
Publisher: Routledge
Release Date : 1997
Epilepsy And Pregnancy written by Torbjörn Tomson and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Epilepsy categories.
Epilepsy in pregnancy poses a serious threat to the mother and to her developing child. Even in previously well-controlled epilepsy, physiological changes in the mother during pregnancy and also during labour and delivery can alter the pharmacokinetic drug (AED) therapy causing increased seizure frequency.
Nonconvulsive Status Epilepticus
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Author : Frank W. Drislane, MD
language : en
Publisher: Demos Medical Publishing
Release Date : 2008-11-05
Nonconvulsive Status Epilepticus written by Frank W. Drislane, MD and has been published by Demos Medical Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-05 with Medical categories.
The only comprehensive source of information on this frequently misdiagnosed problem, with information critical for physicians, ER and ICU doctors, and psychiatrists. An under-recognized condition that can potentially cause brain damage and even death, nonconvulsive status epilepticus (NCSE) is an important clinical problem, occurring in about 25% of status epilepsy cases. Despite this prevalence, Nonconvulsive Status Epilepticus is the first comprehensive clinical text to cover its diagnosis and management. The book progresses logically, beginning with chapters discussing the history and classification of NCSE, reflecting a contemporary understanding of developmental, syndromic, and clinical aspects. Following chapters discuss relevant epidemiology, electrophysiology, imaging and pathophysiology of NCSE, with supplementary sections devoted to psychiatric and behavioral aspects of NCSE and to the different diagnostic considerations of its frequently unusual behavioral presentations. Highlights include: An emphasis on diagnosis, management, and all pertinent clinical issues A heavily illustrated section on EEG interpretation in NCSE Contributions by the foremost international experts on NCSE Throughout, the book maintains a practical focus on recognizing the key signs and symptoms of this subtly presented and clinically challenging condition. This multidisciplinary volume will provide physicians, ER and ICU doctors, and psychiatrists with a comprehensive source of information and opinion on nonconvulsive status epilepticus.
Epilepsy
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Author : Jerome Engel
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2008
Epilepsy written by Jerome Engel and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
Written and edited by world-renowned authorities, this three-volume work is, to quote a reviewer, "the definitive textbook about seizures and epilepsy". This Second Edition is thoroughly updated and gives you a complete print and multimedia package: the three-volume set plus access to an integrated content Website. More than 300 chapters cover the spectrum of biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Included are detailed discussions of seizure types and epilepsy syndromes; relationships between physiology and clinical events; psychiatric and medical comorbidity; conditions that could be mistaken for epilepsy; and an increasing range of pharmacologic, surgical, and alternative therapies, including vagus nerve stimulation and deep brain stimulation. This edition describes many new antiepileptic drugs, major advances in surgical treatment, and state-of-the-art neuroimaging, EEG, and other technologies for diagnosis and seizure prediction. A companion Website offers instant access to the complete, fully searchable text, plus an image bank of additional figures, video footage, and annual updates to selected chapters.
Atlas
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Author : Programme for Neurological Diseases and Neuroscience
language : en
Publisher: World Health Organization
Release Date : 2005
Atlas written by Programme for Neurological Diseases and Neuroscience and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
Epilepsy is one of the most common serious disorders of the brain, affecting about 50 million people worldwide. Epilepsy accounts for 1 per cent of the global burden of disease; 80 per cent of the burden of epilepsy is in the developing world, where in some areas 80-90 per cent of people with epilepsy receive no treatment at all. The Epilepsy Atlas provides an illustrative presentation of data and information on the current status of epilepsy services and care available from 160 countries, areas or territories covering 97.5 per cent of the world population. The information is primarily gathered from key persons in the area of epilepsy care in each country identified by International Bureau for Epilepsy and the International League against Epilepsy, and, in some cases, by WHO regional offices.
Canine And Feline Epilepsy
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Author : Luisa de Risio
language : en
Publisher: CABI
Release Date : 2014-09-23
Canine And Feline Epilepsy written by Luisa de Risio and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-23 with Medical categories.
Epilepsy is one of the most familiar chronic neurological diseases and is a common yet challenging presentation in veterinary surgeries. This book covers seizure pathogenesis, classifications, diagnostic investigations, emergency treatments and longer term treatments, with a large section on pharmacological intervention. Filling a considerable gap in the veterinary literature, it includes tables and charts for quick reference during emergencies. Seizures can be very distressing to animals and owners, yet not all seizures are the result of epilepsy, a neurological condition. This book discusses how to distinguish between epileptic and non-neurological seizures, and provides case studies to illustrate different occurrences of epilepsy.
Quality Of Life In Epilepsy
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Author : Gus A Baker
language : en
Publisher: Psychology Press
Release Date : 2013-05-13
Quality Of Life In Epilepsy written by Gus A Baker and has been published by Psychology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-13 with Medical categories.
Though clinical aspects of epilepsy such as seizure control are crucially important to its management, increasing attention is being given to wider quality of life issues. Epilepsy continues to be an often misunderstood and stigmatising condition; for the vast majority of people whose seizures can be well controlled, the social and psychological repercussions are often of greater significance than the seizures themselves. The increasing emphasis on the importance of non-clinical outcomes in the assessment of new treatments and management strategies for chronic conditions such as epilepsy has stimulated interest in methodological issues in assessing quality of life. This book reviews the recent literature on the impact of epilepsy on everyday experience and the methodological issues involved in assessing that impact. It also considers the perspectives of a range of health professionals involved in caring for people with epilepsy and how, through appropriate management, the impact on their lives can be minimised.