Traversing The Valley Of Death


Traversing The Valley Of Death
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Traversing The Valley Of Death


Traversing The Valley Of Death
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Author : Stephen K Markham Ph D
language : en
Publisher:
Release Date : 2014-12-15

Traversing The Valley Of Death written by Stephen K Markham Ph D and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-15 with Business planning categories.


Traversing the Valley of Death is for managers with responsibility to grow revenue and market share or open new markets and lines of business. The process contained in this book provides a complete system to create new value starting with early needs assessment and continuing through detailed business planning and organizational adoption. This is an advanced book; it assumes managers are well initiated into their markets and company capabilities.



Bridging The Valley Of Death


Bridging The Valley Of Death
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Author : Great Britain: Parliament: House of Commons: Science and Technology Committee
language : en
Publisher: The Stationery Office
Release Date : 2013-03-13

Bridging The Valley Of Death written by Great Britain: Parliament: House of Commons: Science and Technology Committee and has been published by The Stationery Office this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-13 with Science categories.


There exists the concept of a valley of death that prevents the progress of science from the laboratory bench to the point where it provides the basis of a commercially successful business or product. The future success of the UK economy has been linked to the success of translating a world class science base to generate new businesses with the consequent generation of UK jobs and wealth. A troubling feature of technology companies in the UK is how many are acquired by foreign owners where the subsequent jobs and wealth are generated outside the UK. It is key that the Government ensure that sufficient capital is available and recommended that the proposed bank for business, possibly in partnership with the Business Growth Fund, be used to promote a bond market for medium sized businesses, thus providing growing small businesses with an additional source of funding. It is also recommended that the Government investigate the potential to require funds to have a proportion of European SME equities. There needs to be a mechanism to support SME's who do disproportionately badly from the current R&D tax credit scheme. The Technology Strategy Board is becoming the focus for government innovation policy and Government should consider how they can resource the TSB to provide local level advice to technology businesses. The Small Business Research Initiative (SBRI) and the SMART Award scheme would appear to be successful initiatives but lack sufficient funds to meet the demand from companies



Cell Press Reviews Cancer Therapeutics


Cell Press Reviews Cancer Therapeutics
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Author : Cell Press
language : en
Publisher: Elsevier
Release Date : 2013-12-10

Cell Press Reviews Cancer Therapeutics written by Cell Press and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-10 with Medical categories.


Cell Press Reviews: Cancer Therapeutics informs, inspires, and connects cancer researchers at all stages in their careers with timely, comprehensive reviews written by leaders in the field and curated by Cell Press editors. The publicatio offers a broad view of some of the most compelling topics in cancer therapeutics including: Genetic approaches for personal oncology Targeting epigenetic dysregulation and protein interaction networks Vaccines and antibodies in cancer immunotherapy Tumor heterogeneity and chemotherapy resistance Tumor associated macrophages in anticancer treatment Contributions come from leading voices in the field, including: - Daniel A. Haber, Director of Massachusetts General Hospital Cancer Center and Professor at Harvard Medical School - Tony Kouzarides, Professor at the University of Cambridge, Deputy Director of the Wellcome Trust/Cancer Research UK Gurdon Institute, and a founder of the cancer drug discovery company Chroma Therapeutics - Charles L. Sawyers, Chair of the Human Oncology and Pathogenesis Program at Memorial Sloan Kettering Cancer Center, President of the American Association for Cancer Research, member of the presidentially appointed National Cancer Advisory Board, and recipient of the 2013 Breakthrough Prize in Life Sciences Cell Press Reviews: Cancer Therapeutics is part of the Cell Press Reviews series, which features reviews published in Cell Press primary research and Trends reviews journals. Provides timely, comprehensive articles on a wide range of topics in cancer therapeutics Offers insight from experts on genetic, molecular, and cellular aspects of cancer therapy Features reviews on basic science advances translated into drug discovery and therapeutic approaches Includes articles originally published in Cell, Cancer Cell, Trends in Genetics, Trends in Molecular Medicine, and Trends in Pharmacological Sciences



Seemed Like A Good Idea


Seemed Like A Good Idea
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Author : Mark Pauly
language : en
Publisher: Cambridge University Press
Release Date : 2022-07-28

Seemed Like A Good Idea written by Mark Pauly and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-28 with Business & Economics categories.


Consumers, public officials, and even managers of health care and insurance are unhappy about care quality, access, and costs. This book shows that is because efforts to do something about these problems often rely on hope or conjecture, not rigorous evidence of effectiveness. In this book, experts in the field separate the speculative from the proven with regard to how care is rendered, how patients can be in control, how providers should be paid, and how disparities can be reduced – and they also identify the issues for which evidence is currently missing. It provides an antidote to frustration and a clear-eyed guide for forward progress, helping health care and insurance innovators make better decisions on deciding whether to go ahead now based on current evidence, to seek and wait for additional evidence, or to move on to different ideas. It will be useful to practitioners in hospital systems, medical groups, and insurance organizations and can also be used in executive and MBA teaching.



The Role Of The Sbir And Sttr Programs In Stimulating Innovation At Small High Tech Businesses


The Role Of The Sbir And Sttr Programs In Stimulating Innovation At Small High Tech Businesses
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Author : United States. Congress. House. Committee on Science and Technology (2007). Subcommittee on Technology and Innovation
language : en
Publisher:
Release Date : 2009

The Role Of The Sbir And Sttr Programs In Stimulating Innovation At Small High Tech Businesses written by United States. Congress. House. Committee on Science and Technology (2007). Subcommittee on Technology and Innovation and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Business & Economics categories.




Introduction To Translational Cardiovascular Research


Introduction To Translational Cardiovascular Research
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Author : Dennis V. Cokkinos
language : en
Publisher: Springer
Release Date : 2014-11-06

Introduction To Translational Cardiovascular Research written by Dennis V. Cokkinos and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-06 with Medical categories.


The term “Translational Research” reflects today’s integration of basic research (“bench”) findings with the clinical practice of medicine, and in a wider scope the application of results from the individual patient (“bedside”) to entire populations for the improvement of public health. This book offers future researchers a stimulus in many aspects of cardiovascular research, so as to promote their interest in future fields of cardiovascular disease, diagnosis and treatment. Introduction to Translational Cardiovascular Research discusses the fundamental and important aspects of the topic. It describes the renin-angiotensin-aldosterone system, the beta adrenergic receptors and the hypothalamic-pituitary-adrenal axis, while covering genetic polymorphisms both generally and specifically as regards the vascular endothelium and the use of microRNAs. As such, this book will be relevant to young physicians, nurses and other scientists engaged in the clinical cardiovascular field who want to added research-oriented dimension to their efforts towards better understanding and practicing of medicine. It also aims to attract young basic researchers who want to develop a better comprehension of the organism as a whole, man or animal, that they are investigating.



Achieving Proof Of Concept In Drug Discovery And Development


Achieving Proof Of Concept In Drug Discovery And Development
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Author : Helen Yu
language : en
Publisher: Edward Elgar Publishing
Release Date : 2016-11-25

Achieving Proof Of Concept In Drug Discovery And Development written by Helen Yu and has been published by Edward Elgar Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-25 with categories.


One of the major shortcomings of the current drug discovery and development process is the inability to bridge the gap between early stage discoveries and pre-clinical research in order to advance innovations beyond the discovery phase. This book examines a drug discovery and development model, where the respective expertise of academia and industry are brought together to take promising discoveries through to proof of concept, providing a means to de-risk the drug discovery and development process.



Beyond Smoke And Mirrors


Beyond Smoke And Mirrors
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Author : Burton Richter
language : en
Publisher: Cambridge University Press
Release Date : 2010-04-12

Beyond Smoke And Mirrors written by Burton Richter and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-04-12 with Science categories.


Global climate change is one of the most important issues humanity faces today. This book assesses the sensible, senseless and biased proposals for averting the potentially disastrous consequences of global warming, allowing the reader to draw their own conclusions on switching to more sustainable energy provision. Burton Richter is a Nobel Prize-winning scientist who has served on many US and international review committees on climate change and energy issues. He provides a concise overview of our knowledge and uncertainties within climate change science , discusses current energy demand and supply patterns, and the energy options available to cut emissions of greenhouse gases. Written in non-technical language, this book presents a balanced view of options for moving from our heavy reliance on fossil fuels into a much more sustainable energy system, and is accessible to a wide range of readers without scientific backgrounds - students, policymakers, and the concerned citizen.



Green Infrastructure Finance


Green Infrastructure Finance
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Author : Aldo Baietti
language : en
Publisher: World Bank Publications
Release Date : 2012-04-18

Green Infrastructure Finance written by Aldo Baietti and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-18 with Business & Economics categories.


This report is a structured compendium of leading initiatives and activities put forward to accelerate private investment flows in green growth. It summarizes current investment challenges of green projects as well as proposed solutions, financing schemes and initiatives that have set the stage for scaling up green infrastructure investments.



Myocardial Preservation


Myocardial Preservation
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Author : Dennis V. Cokkinos
language : en
Publisher: Springer
Release Date : 2019-01-28

Myocardial Preservation written by Dennis V. Cokkinos and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-28 with Medical categories.


This timely book reveals an integrated approach to myocardial preservation focusing on translational research and clinical applications. Chapters cover both the mechanisms of heart failure in addition to therapeutic considerations, including forms of cardiac cell death, cardiac remodelling and cardiac regeneration. Potential future research directions are also proposed, enabling the reader to gain a broad in-depth understanding of the topic. Myocardial Preservation: Translational Research and Clinical Application presents a thorough review of myocardial preservation. Its comprehensive approach provides a valuable reference for cardiology researchers and practising and trainee cardiologists seeking new insight to the topic.