Treatment Landscape Of Targeted Therapies In Oncology
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Treatment Landscape Of Targeted Therapies In Oncology
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Author : Pawan Kumar Maurya
language : en
Publisher: Elsevier
Release Date : 2023-07-29
Treatment Landscape Of Targeted Therapies In Oncology written by Pawan Kumar Maurya and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-29 with Science categories.
Treatment Landscape of Targeted Therapies in Oncology: Challenges and Opportunities provides up-to-date knowledge on antitumor-targeted therapies and immunotherapy. The book's chapters are written by researchers dynamically working/focusing on cancer treatment. The content is designed to help those who are new to the field (beginners) and various specialized scientists and researchers involved in cancer research. For decades, the hallmark of cancer treatment has been conventional chemotherapy. But with the rapid increase in our understanding of the immune system, more and more small molecules, peptides, recombinant antibodies, vaccines and cellular therapeutic modalities are being applied to manipulate the immune response for cancer treatment. Covers basic concepts and updated knowledge of the latest anticancer drugs Brings comprehensive understanding of the treatment of cancer in context of immunotherapy and targeted therapy Introduces the latest drugs and advancements in the treatment of cancer Includes detailed diagrams to give insight to the mechanisms of action
Targeted Therapies For Solid Tumors
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Author : Antonio Russo
language : en
Publisher: Humana Press
Release Date : 2015-03-11
Targeted Therapies For Solid Tumors written by Antonio Russo and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-11 with Medical categories.
This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical development of new molecularly targeted agents, the use of biomarkers as prognostic, predictive and surrogate endpoints, and the evaluation of tumor response and specific malignancies treated with targeted agents. The book also covers some of the newest developments in cancer therapy that are not adequately covered by any current available literature. Written by recognized experts in the field, Targeted Therapies for Solid Tumors: A Handbook for Moving Toward New Frontiers in Cancer Treatment provides a unique and valuable resource in the field of molecular oncology, both for those currently in training, and for those already in clinical or research practice.
Targeted Therapies In Oncology
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Author : Giuseppe Giaccone
language : en
Publisher: CRC Press
Release Date : 2007-09-25
Targeted Therapies In Oncology written by Giuseppe Giaccone and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-25 with Medical categories.
Targeted therapy is one of the most burgeoning areas of development in cancer research. Increasing knowledge in tumor formation and growth at the molecular level has generated a broad array of therapeutic options, including signal transduction inhibition, anti-angiogenic and anti-vascular agents, cell cycle inhibitors, telomerase and telomere inter
Resistance To Targeted Therapies In Breast Cancer
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Author : Jenifer R. Prosperi
language : en
Publisher: Springer
Release Date : 2017-12-04
Resistance To Targeted Therapies In Breast Cancer written by Jenifer R. Prosperi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-04 with Medical categories.
We present an in-depth description of resistance to targeted therapies in breast cancer. Targeted therapies discussed here include those used to treat ER+ or Her2+ breast cancers (i.e., Tamoxifen or trastuzumab) or those targeting signaling pathways aberrantly activated in triple negative breast cancer (i.e., EGFR and Wnt signaling). We have also provided an overview of standard of care as an introduction into the importance of targeted therapy. It is our hope that this volume gives an insight into the landscape of breast cancer treatment, the challenges of targeted therapy, and a glimpse into the future of breast cancer therapy.
Targeted Therapies In Oncology Second Edition
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Author : Giuseppe Giaccone
language : en
Publisher: CRC Press
Release Date : 2013-10-21
Targeted Therapies In Oncology Second Edition written by Giuseppe Giaccone and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-21 with Medical categories.
Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the development of new anticancer agents that have the ability to block the activity of proteins involved in neoplastic cell development and proliferation. Targeted Therapies in Oncology, Second Edition provides a concise timely panorama of existing targeted therapies and progress into future anticancer treatments. These therapies notably include: Targeted agents of immune checkpoints Signal-transduction inhibitors Antiangiogenic agents Vascular-disrupting agents Apoptosis modulators Stem cell inhibitors Tumor profiling for drug development The book emphasizes the biology behind this new class of drugs as well as the clinical achievements obtained. The contributors to this volume stand at the cutting edge of cancer research and treatment around the world.
Targeted Cancer Therapy
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Author : Razelle Kurzrock
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-03-07
Targeted Cancer Therapy written by Razelle Kurzrock and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-07 with Medical categories.
Emerging technologies in target identification, drug discovery, molecular markers, and imaging are rapidly changing the face of cancer. This book provides a foundation of knowledge in targeted cancer therapeutics. The treatment of cancer is increasingly being individualized, based on an understanding of underlying biologic mechanisms. Poised to change the landscape in oncology, this volume provides a state-of-the-art overview. It will be valuable to practicing and academic physicians, fellows, residents and students, as well as basic scientists, interested in the cancer field.
Targeted Therapy Of Acute Myeloid Leukemia
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Author : Michael Andreeff
language : en
Publisher: Springer
Release Date : 2014-11-20
Targeted Therapy Of Acute Myeloid Leukemia written by Michael Andreeff and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-20 with Medical categories.
This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.
Handbook Of Targeted Cancer Therapy And Immunotherapy
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Author : Daniel Karp
language : en
Publisher: LWW
Release Date : 2022-05
Handbook Of Targeted Cancer Therapy And Immunotherapy written by Daniel Karp and has been published by LWW this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05 with Medical categories.
Designed for quick, everyday reference, Handbook of Targeted Cancer Therapy and Immunotherapy, 3rd Edition, includes clinical trial results of more than 190 state-of-the-art targeted therapy and immunotherapy agents, providing a practical, intuitive, colorful overview of this rapidly advancing field. Comprehensive yet concise, this easy-access resource by Drs. Daniel D. Karp, Gerald S. Falchook, and JoAnn D. Lim, helps you navigate through the newest research reports and apply the most recent discoveries as they pertain to specific tumor types, actionable molecular targets, and clinical performance of investigational targeted agents and combinations of agents. This handbook presents information distilled by dozens of translational research clinicians and other healthcare experts with hundreds of years of cumulative experience in the revolutionary area of genomically based precision oncology. Covers cancer targets--phase 1, 2, and 3 trials and preliminary results, as well as approved therapies. Includes sections on Molecular Targets and Pathways, and Targeted and Immunotherapy Agents. Contains a section on Carcinogenesis from the Perspective of Targeted Therapy and Immunotherapy, with essential content on biology, immunology, and immunotherapy. Organizes information by tumor type, pathway, and drug name, so you can approach clinical challenges from any direction. Highlights FDA approvals throughout. Pocket-sized and color coded to help you find information quickly and easily. Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.
Molecularly Targeted Therapy For Childhood Cancer
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Author : Peter J. Houghton
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-10
Molecularly Targeted Therapy For Childhood Cancer written by Peter J. Houghton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-10 with Medical categories.
Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular ‘drivers’ can be exploited from a therapeutic standpoint with currently available targeted agents. Where applicable, integration of targeted therapies with conventional cytotoxic agents will be considered. This volume will provide a comprehensive summary of molecular characteristics of childhood cancers, and how the changes involved in transformation provide us with opportunities for developing relatively less toxic, but curative, therapies.
Targeted Therapy In Translational Cancer Research
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Author : Apostolia-Maria Tsimberidou
language : en
Publisher: John Wiley & Sons
Release Date : 2015-10-14
Targeted Therapy In Translational Cancer Research written by Apostolia-Maria Tsimberidou and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-14 with Medical categories.
Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy. Introduces cutting-edge ‘bench to bedside and back’ breakthroughs which have transformed the diagnosis, prognosis, and treatment of cancer Covers basic principles of targeted therapy, including immunotherapy and the roles of cancer stem cells, the microenvironment, angiogenesis, epigenetics, microRNAs, and functional imaging in precision medicine Summarises major advances in therapeutic management of hematologic malignancies and solid tumors using conventional therapy, targeted therapy, immunotherapy, or novel treatment modalities