Treatment With Ursodeoxycholic Acid In Clinical Hepatology
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Treatment With Ursodeoxycholic Acid In Clinical Hepatology
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Author : Kurt Einarsson
language : en
Publisher:
Release Date : 1994
Treatment With Ursodeoxycholic Acid In Clinical Hepatology written by Kurt Einarsson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with categories.
Treatment With Ursodeoxycholic Acid In Clinical Hepatology
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Author : Kurt Einarsson
language : en
Publisher:
Release Date : 1994
Treatment With Ursodeoxycholic Acid In Clinical Hepatology written by Kurt Einarsson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Bile acids categories.
Primary Biliary Cirrhosis
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Author : Keith D. Lindor
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Primary Biliary Cirrhosis written by Keith D. Lindor and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The condition of prolonged obstructive jaundice with patent bile ducts was first described in 1851 by Addison and Gull of Guy's Hospital, London. The term primary biliary cirrhosis (PBC) was defined in 1950 by Ahrens and colleagues of the Rockefeller Institute, New York. The condition was considered rare but this changed in 1965 with the discovery of a definitive diagnostic serum mitochondrial antibody test and the recognition that a raised serum alkaline phosphatase value, often discovered incidentally, could be a diagnostic pointer. If the diagnosis is made earlier, the end stages are rarely reached as death is replaced by liver transplantation. On November 6th 1997, in Chicago, an International Faculty discussed in depth the clinical features, pathogenesis and treatment of PBC, no longer considered a rare disease. The course of PBC is long, but some 18 years after the discovery of a positive mitochondrial antibody test in a symptom free patient with normal serum biochemistry, 83% will have developed abnormal tests and 76% will be symptomatic. Identification of those who will progress rapidly is difficult. The serum antimitochondrial profile may be useful but this is a very specialist technique. Mathematical prognostic models are useful in therapeutic trials and in the selection and timing of patients for liver transplantation but have limited value in individual patients. An increasing serum bilirubin level remains the most important indicator of rapid progression. Its value however can be negated by the use of ursodeoxycholic acid which has a bilirubin-lowering effect.
Bile Acids In Gastroenterology
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Author : Susumu Tazuma
language : en
Publisher: Springer
Release Date : 2017-04-03
Bile Acids In Gastroenterology written by Susumu Tazuma and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-03 with Medical categories.
This book examines the biological aspects of bile acid analysis and their clinical applications, providing readers with an overview of cutting-edge discussions on Bile Acid research and diseases. It begins with detailed discussions on the biological aspects of bile acid, with chapters examining bile acid from various perspectives, from its metabolism to its use in therapeutic agents. Subsequent chapters focus on diseases involving bile acid abnormalities, and specific applications are addressed concerning gallstones, cholestatic liver disease, NAFLD/NASH, hepatitis, pancreatitis, esophageal cancer and colon cancer. In keeping with the book’s integrated approach, the Editor has gathered a broad range of eminent scholars and practitioners to provide a comprehensive review of modern bile acid research. The book offers clinical physicians, basic researchers and postgraduate students essential insights into cutting-edge research and paves the way for further research.
Bile Acids In Hepatobiliary Disease
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Author : T.C. Northfield
language : en
Publisher: Springer Science & Business Media
Release Date : 2000-02-29
Bile Acids In Hepatobiliary Disease written by T.C. Northfield and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-02-29 with Medical categories.
This book is the proceedings of the Falk Workshop on `Bile Acids in Hepatobiliary Disease', which took place at the Royal Society of Medicine (RSM) in London, UK, on 29-30 March 1999, and was held in association with the Section of Measurement in Medicine at the RSM. The main interest in bile acid therapy has been recently in cholestatic liver disease. The proceedings of the workshop not only discusses this, but moves on to examine its possible use in alcoholic liver disease, and moves back to re-examine its role in biliary disease. Leading world experts attempt to define its mechanism of action, and the current role of other non-surgical treatments in biliary disease. The physiology and pathogenesis of cholestatic and alcoholic liver disease and cholesterol gallstone disease is also examined.
Bile Acids And The Hepatobiliary System
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Author : G. Paumgartner
language : en
Publisher: Springer
Release Date : 1993-06-30
Bile Acids And The Hepatobiliary System written by G. Paumgartner and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-06-30 with Medical categories.
Bile acids have recently found application in the treatment of hepatobiliary diseases. Chenodeoxycholic acid and ursodeoxycholic acid have proved to be effective agents for the dissolution of cholesterol gallstones, and ursodeoxycholic acid has been shown to have beneficial effects in patients with chronic cholestatic liver disease such as primary biliary cirrhosis or primary sclerosing cholangitis. The question of the long-term benefit for the patient remains open and the mechanism of action is still unclear. As a consequence, much basic and clinical research is being conducted on bile acid therapy. The XIIth International Bile Acid Meeting brought together researchers and clinicians from around the world, and was dedicated to basic and clinical aspects of the use of bile acids in the therapy of hepatobiliary disease.
Liver Disorders
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Author : Kia Saeian
language : en
Publisher: Springer
Release Date : 2016-12-20
Liver Disorders written by Kia Saeian and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-20 with Medical categories.
This book is a comprehensive and easy-to-access guide not only in the diagnosis of the various types of liver disease but in the management of specific disorders, including the particular nuances of the care of the patient with liver disease. It provides a resource to the practitioner caring for patients with liver disease for addressing everyday questions posed by patients and their families, as well as referring physicians, in a manner that can easily be conveyed. The spectrum covered includes appropriate testing and disease monitoring of patients, use of medications, supplements, alternative therapies and alcohol, operative risk assessment, implementation of health maintenance for patients with chronic liver disease and cirrhosis, identification and management of particular complications of cirrhosis, and appropriate referral for liver transplantation, as well as management of special populations. Written by experts in the field, Liver Disorders: A Point of Care Clinical Guide is a valuable resource for clinicians who treat patients with a variety of liver disorders.
Cholestatic Liver Diseases Therapeutic Options And Perspectives
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Author : U. Leuschner
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-06-30
Cholestatic Liver Diseases Therapeutic Options And Perspectives written by U. Leuschner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-06-30 with Medical categories.
During the last decade, knowledge about cholestatic liver disease and concomitant diseases, such as ulcerative colitis, cholangio- and hepatocellular carcinoma, pancreas and colon cancer, has increased considerably. Studies on ursodeoxycholic acid treatment alone or in combination with immunosuppressive compounds and their positive effects on biliary liver disease as well as on so-called overlap syndromes or intestinal tumors are published in increasing numbers, and stimulate discussion on whether or not ursodeoxycholic acid is able to improve the general condition and/or life expectancy of patients. On the other hand, genetics, aetiological and pathogenetic aspects are still difficult to comprehend, but are the absolute prerequisite for the development of better treatment options. This book is the proceedings of Falk Symposium No. 136 (Part I of the XII Falk Liver Week, held in Freiburg, Germany, on October 15-16, 2003), and contains stimulating, exciting and controversial papers on clinical and also basic research at the highest scientific level.
Primary Biliary Cholangitis An Issue Of Clinics In Liver Disease E Book
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Author : Elizabeth J Carey
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-07-13
Primary Biliary Cholangitis An Issue Of Clinics In Liver Disease E Book written by Elizabeth J Carey and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-13 with Medical categories.
The Guest Editors have put together an issue of clinical reviews that provides the most current look at PBC. Authors, all experts in their respective areas, have submitted articles in the following areas: Changes in epidemiology of PBC; Genetic and epigenetics in PBC; Role of bile acids and the bicarbonate umbrella in the pathogenesis of PBC; Current treatment options in PBC; Work in progress: Drugs in development; Natural history of PBC in the UDCA era: Role of scoring systems; Treatment of Pruritus: Tricks of the trade; Chronic complications of cholestasis: Work-up and Management; Individualizing care: Management beyond medical therapy; Role of liver biopsy: When to do, how to stage; AMA-negative PBC: Is it really the same as AMA-positive PBC?; New thoughts on Overlap syndrome with auto-immune hepatitis; and Current status of liver transplantation for PBC.
Bile Acid Biology And Its Therapeutic Implications
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Author : G. Paumgartner
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-03-02
Bile Acid Biology And Its Therapeutic Implications written by G. Paumgartner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-03-02 with Medical categories.
This book is the proceedings of the 18th International Bile Acid Meeting, held as the Falk Symposium 141 in Stockholm, Sweden, on June 18–19, 2004. The International Bile Acid Meetings have become some of the most important meetings in the bile acid field worldwide since Herbert Falk decided to sponsor these Symposia in biannual sequence in 1970. The 17 International Bile Acid Meetings in the past have been a great stimulus for new ideas and methods as well as the development of therapeutic applications of bile acids. They have always been a forum where basic scientists and clinicians interact. Many novel results of bile acid research were first presented at these meetings. The meeting in Stockholm again attracted a large number of basic and clinical scientists interested in bile acid and biliary research from all over the world. Knowledge about the regulation of bile acid synthesis, bile acid transport and enterohepatic circulation in health and in disease has increased considerably during recent years. Accordingly, bile acid research is alive as ever. A new chapter of bile acid research was opened by the finding that bile acids are ligands of nuclear receptors which regulate synthesis, metabolism and transport of bile acids and steroids. A large part of the book is devoted to these topics. The 18th International Bile Acid Meeting was again a truly interdisciplinary symposium at the highest scientific level. Its participants enjoyed hearing the latest reports on bile acid research in the city where so many seminal studies on bile acids were performed. It is hoped that the readers of this book will share the enjoyment.