Trp Channels In Inflammation And Immunity
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Trp Channels In Inflammation And Immunity
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Author : Santiago Partida Sanchez
language : en
Publisher: Frontiers Media SA
Release Date : 2021-06-08
Trp Channels In Inflammation And Immunity written by Santiago Partida Sanchez and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-08 with Medical categories.
Itch
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Author : E. Carstens
language : en
Publisher: CRC Press
Release Date : 2014-02-25
Itch written by E. Carstens and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-25 with Science categories.
Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.
Innovative Medicine
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Author : Kazuwa Nakao
language : en
Publisher: Springer
Release Date : 2015-10-13
Innovative Medicine written by Kazuwa Nakao and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-13 with Science categories.
This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.
New Insights Into Mechanotransduction By Immune Cells In Physiological And Pathological Conditions
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Author : Shaik O. Rahaman
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-11
New Insights Into Mechanotransduction By Immune Cells In Physiological And Pathological Conditions written by Shaik O. Rahaman and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-11 with Medical categories.
Oxidative Stress In Lung Diseases
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Author : Sajal Chakraborti
language : en
Publisher: Springer Nature
Release Date : 2019-11-23
Oxidative Stress In Lung Diseases written by Sajal Chakraborti and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-23 with Science categories.
This is the second volume of the comprehensive, two-volume work on oxidative stress in lung diseases. Adopting a multidisciplinary approach, it demonstrates the cellular and molecular mechanisms associated with ROS (reactive oxygen species)-induced initiation and progression of a variety of lung diseases, such as COPD, emphysema, asthma, cystic fibrosis, occupational pulmonary diseases and pulmonary hypertension and discusses points for therapeutic intervention. The book also covers translational research and the latest research on prevention and therapeutics. Each chapter includes in-depth insights into the mechanisms associated with lung diseases and into identifying targets for drug development. Bridging the gap between fundamental and translational research, and examining applications in the biomedical and pharmaceutical industry, it is a thought- provoking read for basic and applied scientists engaged in biomedical research.
Inflammation In Skin Related Diseases
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Author : Chunmeng Shi
language : en
Publisher: Frontiers Media SA
Release Date : 2024-08-21
Inflammation In Skin Related Diseases written by Chunmeng Shi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-21 with Medical categories.
It has been revealed that inflammation plays an important role in the progression of skin-related diseases, including burn or trauma wounds, diabetes wounds, pressure ulcers, radiation ulcers, keloids, hypertrophic scars, dermatitis, eczema, psoriasis, vitiligo, etc, causing skin tissue to exhibit over-inflammation, lower inflammation, or chronic inflammation. During this process, bacteria invasion, microbiota dysbiosis, or autoimmunity are known as the general initiators to induce the abnormal activity of immune cells and molecules and could change the crosstalk between immune cells and repair cells (or interstitial cells). Therefore, the research deep into the novel mechanisms of inflammation, the new signal pathway of immunity chain responses, or the new relationship between inflammation and repair cells, is of great interest for the design of novel therapies for skin-related diseases.
Neurobiology Of Trp Channels
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Author : Tamara Luti Rosenbaum Emir
language : en
Publisher: CRC Press
Release Date : 2017-08-09
Neurobiology Of Trp Channels written by Tamara Luti Rosenbaum Emir and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-09 with Science categories.
During the last two decades, there has been an explosion of research pertaining to the molecular mechanisms that allow for organisms to detect different stimuli that is an essential feature for their survival. Among these mechanisms, living beings need to be able to respond to different temperatures as well as chemical and physical stimuli. Thermally activated ion channels were proposed to be present in sensory neurons in the 1980s, but it was not until 1997 that a heat- and capsaicin- activated ion channel, TRPV1, was cloned and its function described in detail. This groundbreaking discovery led to the identification and characterization of several more proteins of the family of Transient Receptor Potential (TRP) ion channels. Intensive research has provided us with the atomic structures of some of these proteins, as well as understanding of their physiological roles, both in normal and pathological conditions. With chapters contributed by renowned experts in the field, Neurobiology of TRP Channels contains a state- of- the- art overview of our knowledge of TRP channels, ranging from structure to their functions in organismal physiology. Features: • Contains chapters on the roles of several TRP ion channels with a diversity of physiological functions, providing a complete picture of the widespread importance of these proteins. • Presents an overview of the structure of TRP channels, including the roles of these proteins in different physiological processes. • Discusses the roles of TRP channels in pathophysiological processes, further highlighting their importance. • Features several full color illustrations to allow the reader better comprehension of TRP channels. A volume in the Frontiers in Neuroscience series
Immune Cells Inflammation And Cardiovascular Diseases
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Author : Shyam S. Bansal
language : en
Publisher: CRC Press
Release Date : 2022-04-19
Immune Cells Inflammation And Cardiovascular Diseases written by Shyam S. Bansal and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-19 with Medical categories.
Inflammation, once considered a physiological response to foreign pathogens, is now recognized as a crucial pathological player in the initiation and progression of several chronic diseases, including diabetes, obesity, cancer, Alzheimer’s disease, Parkinson’s disease, and many others. Considering that cardiovascular diseases are a leading cause of death in the United States and worldwide, the identification of critical inflammatory processes is of utmost importance to devising new immune-based therapeutics that can be added to existing regimens. This book provides detailed information on aspects of inflammation and the manner in which immune activation pathways affect the progression of cardiovascular diseases and the repair/regeneration mechanisms of underlying diseased tissues. Key Features Outlines the role that inflammation plays in cardiovascular diseases Describes a paradox – neutralization of cytokines that contribute to cardiovascular disease does not show benefit Summarizes research on a variety of processes and mechanisms contributing to cardiovascular pathology Contributions from an international team of leading cardiologists and cardiovascular immunologists Related Titles Roy, S., et al., eds. Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions (ISBN 978-1-138-19955-2) Kong, A-N. T., ed. Inflammation, Oxidative Stress, and Cancer: Dietary Approaches for Cancer Prevention (ISBN 978-1-138-19984-2) Dick, A., et al. Practical Manual of Intraocular Inflammation (ISBN 978-0-367-38720-4)
Neuroimmunology Of The Inner Ear
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Author : Agnieszka J. Szczepek
language : en
Publisher: Frontiers Media SA
Release Date : 2021-03-12
Neuroimmunology Of The Inner Ear written by Agnieszka J. Szczepek and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-12 with Medical categories.
Pruritus Medicine
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Author : Sonja Ständer
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-24
Pruritus Medicine written by Sonja Ständer and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-24 with Medical categories.