Tumors Of The Central Nervous System Volume 12
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Tumors Of The Central Nervous System Volume 12
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Author : M.A. Hayat
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-12
Tumors Of The Central Nervous System Volume 12 written by M.A. Hayat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-12 with Medical categories.
As in the case of its eleven predecessors in the series Tumors of the Central Nervous System, this volume is distinguished for its thorough approach, its roster of 92 distinguished contributors representing 11 different countries and its detailed examination of leading-edge technology and methods. Volume 12: Molecular Mechanisms, Children’s Cancer, Treatments, and Radiosurgery offers a comprehensive review of the diagnosis, therapy and prognosis of brain and spinal cord tumors. Coverage extends to a large number of tumor types, including neuroblastoma, medulloblastoma, meningioma and chordoma. Molecular profiling of brain tumors to select appropriate therapy in clinical trials of brain tumors is discussed in detail, as is the classification/diagnosis of brain tumors based on function analysis. CDK6 as the molecular regulator of neuronal differentiation in the adult brain, and the role of aquaporins in human brain tumor growth are explained. Discussion also includes tumors affecting children, including neuroblastoma and medulloblastoma. A full chapter is devoted to the role of molecular genetic alterations in medulloblastoma, and another examines survival differences between children and adults with medulloblastoma. The use of various types of imaging methods to diagnose brain tumors is explained. In-depth discussion of treatment options includes stereotactic radiosurgery, endoscopic neurosurgery, electrochemotherapy, transsphenoidal surgery, focal ablation, whole brain radiation therapy and recraniotomy.
Tumors Of The Central Nervous System Volume 14
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Author : M.A. Hayat
language : en
Publisher: Springer
Release Date : 2015-10-05
Tumors Of The Central Nervous System Volume 14 written by M.A. Hayat and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-05 with Medical categories.
This fourteenth volume of the series provides comprehensive, current information on the diagnosis, therapy and prognosis of brain tumors and spinal tumors. For the readers' convenience, contributions are organized into three categories of Pineal Tumors, Pituitary Tumors, and Spinal Tumors. Readers will find discussion of various aspects of a number of tumor types, including angiocentric glioma, pilomyxoid astrocytoma, pituicytoma, pediatric low-grade gliomas, meningiomas and spinal cord tumors. Expert oncologists, neurosurgeons, physicians, research scientists and pathologists from around the world have contributed to this extensive publication. Their chapters highlight practical experience and provide exceptional insight into the nature of cancer. The authors cover topics ranging from the use of molecular criteria in diagnosis and targeting of medicine, through evidence-based approaches, to in-depth discussion of long-term follow-up after surgery. This handbook, as earlier volumes in the series, will appeal to professionals involved in the treatment of cancer, as well as to researchers. The series crosses subjects of diagnosis, drug development, therapy and its assessment and prognosis of tumors of the central nervous system, cancer recurrence and resistance to chemotherapy.
Tumors Of The Central Nervous System Volume 13
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Author : M.A. Hayat
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-16
Tumors Of The Central Nervous System Volume 13 written by M.A. Hayat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-16 with Medical categories.
Volume 13: Pineal, Pituitary, and Spinal Tumors is organized in six sections, for convenience and quick access to critical information. Section I, Types of Tumors includes a chapter on molecular characterization of Embryonal tumors, a chapter on diagnosis of metastatic oligodendroglioma using fine-needle aspiration cytology, one covering intra-arterial chemotherapy of oligodendroglial tumors and another on the role of cyclooxygenase-2 in the development and growth of Schwannomas, and others, closing with a chapter on trigeminal neuralgia with cerebellopontine angle tumors. Section II, Diagnosis, includes two chapters on cell counting in histopathologic slides of tumors. Section III offers three chapters which discuss aspects of intraoperative ultrasonography. Section IV covers brain tumor surgery, and Section V surveys Brain Metastasis. The final section offers a wide-ranging review of General Diseases, with chapters on, among others, Alexander Disease; Lipoma; Transplantation of human umbilical cord blood mononuclear cells in cases of neonatal hypoxic-ischemic brain damage; and a chapter discussing the use of mobile phones and brain cancer risk in children. Like its twelve predecessors in the series, this volume merits distinction for its thorough approach, its roster of 78 distinguished contributors representing 14 different countries and its detailed examination of leading-edge technology and methods.
Who Classification Of Tumours Of The Central Nervous System
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Author : International Agency for Research on Cancer
language : en
Publisher: World Health Organization
Release Date : 2007
Who Classification Of Tumours Of The Central Nervous System written by International Agency for Research on Cancer and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
"WHO Classification of Tumours of the Central Nervous System" is the first volume of the 4th Edition of the World Health Organization series on histological and genetic typing of human tumors. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria pathological features and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, incidence age and sex distribution, location, clinical signs and symptoms, pathology, genetics, and predictive factors. This book is in the series commonly referred to as the "Blue Book" series. The book prepared by 73 authors from 19 countries contains more than 400 color photographs, numerous X-rays, computed tomography (CT), magnetic resonance (MR) images, charts and more than 2,500 references. ."..The title of this book is typically modest. It is not only a classification of tumours of the central nervous system but an authoritative and explicit account of this group of tumours...This the fourth edition contains a number of distinct improvements on previous editions both in layout and content... One new feature is the clear account of the WHO's grading system its rationale and its application... New tumour entities are included...Newly recognized histological variants include pilomyxoid astrocytoma. Both anaplastic medulloblastoma and medulloblastoma with extensive nodularity have gained recognition in the classification... There are some differences in classification from the third edition most notably relating to anaplastic oligoastrocytoma. The change in emphasis follows cited differences in prognosis between mixed tumours with and without necrosis. Other changes are also apparent e.g. within the atypical teratoid/rhabdoid section mention of the INI-1 locus in the genetics section in the third edition has been expanded to include immunohistochemistry in the fourth edition. The fourth edition is unique in its clear-targeted and succinct style of presentation of tumors of the CNS... it will be of universal appeal in neuro-oncology and will most certainly form the main basis for diagnosis by multidisciplinary teams managing patients with tumors of the CNS." -- Nicki Cohen* and Roy O. Weller** *Specialist Registrar in Neuropathology Southampton University Hospital NHS Trust UK. ** Emeritus Professor of Neuropathology Southampton University UK in" Neuropathology and Applied Neurobiology. ."..Representing the first volume in the fourth edition series of the World Health Organization (WHO) Classification of Tumours this book provides a welcome mix of old and new. ... Perhaps the most noticeable improvement comes by way of a voluminous expansion in the genetics sections of the majority of tumor categories. This update parallels the recent explosion of research utilizing high-resolution genome screening and other molecular techniques. The authors have done an outstanding job in distilling the information housed in over 2,500 cited references into a reader friendly authoritative reference of CNS neoplasia. In summation, the current edition of the "WHO Classification of Tumours of the Central Nervous System" will serve as an indispensable textbook for all of those involved in the diagnosis and management of patients with tumors of the CNS and will make a valuable addition to libraries in pathology, radiology, oncology and neurosurgery departments. --"Journal of Neuropathology & Exp. Neurol."Contributors: Dr. Kenneth D. Aldape, Dr. Cristina R. Antonescu, Dr. Albert J. Becker, Dr. Jacklyn A. Biegel, Dr. Wojciech Biernat, Dr. Darell D. Bigner, Dr. Ingmar Blumcke, Dr. Fredrik T. Bosman, Dr. Sebastian Brandner, Dr. Daniel J. Brat, Dr. Herbert Budka, Dr. Peter C. Burger, Dr. Webster K. Cavenee, Dr. Leila Chimelli, Dr. V. Peter Collins, Dr. Catherine Daumas-Duport, Dr. Martina Deckert, Dr. Charles G. Eberhart, Dr. David W. Ellison, Dr. Charis Eng, Dr. Dominique Figarella-Branger, Dr. Gregory N. Fuller, Dr. Felice Giangaspero, Dr. Caterina Giannini, Dr. Hannu Haapasalo, Dr. Pierre Hainaut, Dr. Johannes A. Hainfellner, Dr. Volkmar H. Hans, Dr. Cynthia Hawkins, Dr. Stephen Hunter, Dr. Anne Jouvet, Dr. Alexander R. Judkins, Dr. Paul Kleihues, Dr. Andrey Korshunov, Dr. Johan M. Kros, Dr. Arielle Lellouch-Tubiana, Dr. Suet Yi Leung, Dr. Pawel Liberski, Dr. M. Beatriz S. Lopes, Dr. David N. Louis, Dr. Masao Matsutani, Dr. Roger E. Mclendon, Dr. Yoichi Nakazato, Dr. Hartmut P.H. Neumann, Dr. Ho-Keung Ng, Dr. Hiroko Ohgaki, Dr. Magali Olivier, Dr. Werner Paulus, Dr. Arie Perry, Dr. Torsten Pietsch, Dr. Karl H. Plate, Dr. Matthias Preusser, Dr. Guido Reifenberger, Dr. Federico Roncaroli, Dr. Marc K. Rosenblum, Dr. Elisabeth J. Rushing, Dr. Chitra Sarkar, Dr. Bernd W. Scheithauer, Dr. Davide Schiffer, Dr. Sursala K. Shankar, Dr. Mehar C. Sharma, Dr. Dov Soffer, Dr. Figen Soylemezoglu, Dr. Anat O. Stemmer-Rachamimov, Dr. Ana Lia Taratuto, Dr. Tarik Tihan, Dr. Erwin G. Van Meir, Dr. Scott R. Vandenberg, Dr. Andreas Von Deimling, Dr. Alexander O. Vortmeyer, Dr. Pieter Wesseling, Dr. Otmar D. Wiestler, Dr. James M. Woodruff, Dr. David Zagzag"
Tumors Of The Central Nervous System Volume 7
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Author : M.A. Hayat
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-02-22
Tumors Of The Central Nervous System Volume 7 written by M.A. Hayat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-22 with Medical categories.
Various aspects, including diagnosis, therapy, and prognosis, of two brain tumors (meningioma and schwannoma) , of brain tumors are discussed in this volume. Insights on the understanding of molecular pathways involved in brain tumor biology are explained. For example, the role of E-cadherin gene instability, carbonic anhydrase 11, urokinase plasminogen activator, and Wnt signaling is discussed in detail. Such information will lead to the development of effective aniicancer drugs. The role of molecular genetics and epigenetic mechanisms in schwannomas is explained. Also, is explained the role of cyclin D1 in vestibular schwannoma. The determination of subtypes of meningiomas using perfusion magnetic resonance imaging is explained. Diagnosis of incidentally discovered meningioma and cystic papillary meningioma is also included. Diagnosis of facial nerve schwannoma, vestibular schwannoma, and intermediate nerve schwannoma is explained. Treatments for atypical meningioma, oncocytic meneingioma, intracranial meningioma, and cavernous are presented. Therapeutic methods such as neurosurgery, Gamma knife radiosurgery, and adjuvant radiation for this cancer are included. Large number of other treatments, including radiosurgery, retrosigmoidal craniotomy, and immunotherapy, for vestibular schwannoma patients are detailed.
Tumors Of The Central Nervous System Volume 11
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Author : M.A. Hayat
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-08-20
Tumors Of The Central Nervous System Volume 11 written by M.A. Hayat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-20 with Medical categories.
Like the ten preceding volumes in the series Tumors of the Central Nervous System, this book is distinguished for its comprehensive approach, its distinguished roster of some 93 contributors representing 8 different countries and its embrace of leading-edge technology and methods. Volume 11: Imaging, Glioma and Glioblastoma, Stereotactic Radiotherapy, Spinal Cord Tumors, Meningioma, and Schwannomas concentrates on the diagnosis, prognosis and therapy of four types of tumors, namely Glioblastoma, Meningioma, Schwannoma and Spinal Tumors. The book offers an in-depth survey of a range of new technologies and their applications to tumor diagnosis, treatment and therapy assessment. The contributors explain in thorough detail a range of current and newly developed imaging methods, including molecular imaging and PET scan. Also covered is molecular profiling of brain tumors to select therapy in clinical trials of brain tumors. Discussion includes a review of such surgical treatments as resection and the application of non-invasive stereotactic radiosurgery for treating high-risk patients with brain metastasis. Additional discussion is devoted to tumor seeding.
Tumors Of The Central Nervous System Volume 10
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Author : M.A. Hayat
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-22
Tumors Of The Central Nervous System Volume 10 written by M.A. Hayat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-22 with Medical categories.
Adding to a vitally important cycle of publications covering the latest research developments in our understanding of neoplasms affecting the human central nervous system, this edition focuses on numerous aspects of pineal, pituitary, and spinal tumors. As with the previous volumes in the series, this latest work addresses a central imperative in cancer research—the need to standardize classifications, written definitions and investigative guidelines in order to achieve a measure of shared objectivity among academics engaged in one of the most important medical endeavors of our era. It brings together the very latest work by oncologists, neurosurgeons, physicians, research scientists, and pathologists, providing the medical community with a wealth of data and results that, taken together, will advance the cause of cancer research. The volume synthesizes work on diagnosis, drug development, and therapeutic approaches that are typically scattered in a variety of journals and books. It features promising recent work in applying molecular genetics to clinical practice and evidence-based therapy, covering molecular profiling of tumors as well as a number of surgical treatments such as resection and radiosurgery. Together with its counterpart publications, it represents a much-needed central resource that will inform and guide future research efforts.
Childhood Cancer And Functional Impacts Across The Care Continuum
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Author : National Academies of Sciences Engineering and Medicine
language : en
Publisher:
Release Date : 2021-09-09
Childhood Cancer And Functional Impacts Across The Care Continuum written by National Academies of Sciences Engineering and Medicine and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-09 with categories.
Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.
Tumors Of The Central Nervous System Volume 3
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Author : M.A. Hayat
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-05-27
Tumors Of The Central Nervous System Volume 3 written by M.A. Hayat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-27 with Medical categories.
The classification of brain tumors is up-dated using magnetic resonance spectroscopy technology. The role of cellular immortality in brain tumors is reviewed. Tumor to tumor metastases are a common occurrence; for example, , brain metastasis from breast cancer, lung cancer, and renal cancer is discussed. Genetic profiling and treatment (including neurosurgery) of such brain cancers are explained. Breast cancer patients treated with certain drugs (e.g., capecitabine and lapatinib can develop CNS tumors. Role of brain tumor suppressor genes (e.g., NRP/B gene) is pointed out. Biomarkers used to diagnose brain malignancies are explained in detail. A number of imaging modalities used for diagnosing and assessing the effectiveness of treatments of brain tumors are presented. The imaging methods discussed include MRI, PET, CT, MRSi, and SPECT. Also, is discussed the impact of PET using radiolabeled amino acids on brain tumors.
Tumors Of The Central Nervous System Volume 2
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Author : M.A. Hayat
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-04-03
Tumors Of The Central Nervous System Volume 2 written by M.A. Hayat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-03 with Medical categories.
Advantages and limitations of biomarkers in gliomagenesis are described. Molecular subtypes of gliomas are detailed. The role played by TP53 gene mutation in the deadliest brain tumor, glioblastoma multiforme, is pointed out. The role of mutations of IDH1 and IDH2, and isocitrate dehydrogenases in malignant gliomas are presented. Metabolic differences in different regions of the glioma tumor are clarified. Various types of imaging modalities, including PET and SPECT, to diagnose gliomas in general and glioblastoma in particular in patients are explained in detail. Both low-grade and high-grade gliomas are discussed. Conventional as well as fluorescent-guided resection techniques for high-grade, recurrent malignant gliomas are detailed. Impact of resection extent on outcomes in patients with high-grade gliomas is clarified. The advantage of the use of intraoperative low-field MRI in glioma surgery is explained.