Unclassifiable Leukemias
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Unclassifiable Leukemias
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Author : M. Bessis
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Unclassifiable Leukemias written by M. Bessis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Jean BERNARD * I should like to begin with an assumption and a paradox. The assumption is that leukemia is a disease of a stem cell characterized by pathologie alterations of that cell and its progeny. All present research and discussions are centered around the leukemic cell. So is this symposium, which would not take place except for our primary interest in the leukemic cell. This does not preclude, of course, consideration of other definitions and other approaches to the prOblem. By definition, then, the leukemic cells are abnormal cells and their metabolism and functions are presumed to be abnormal. Yet, the classification of the different types of leukemias is based upon the characteristics of normal cells. We talk of "lymphoblasts" and "myeloblasts" as predominant cell types in leukemia. This leads to a double paradox. In the first pi ace it is clearly illogical to classify abnormal cells by their resemblance to normal cells, since their very abnormality consists in not being normal. Yet, as a second paradox, the classifica ti on has had the happy consequence of ai ding us in the treatment and prognosis of leukemia for the past 25 years. A more detailed analysis shows that the consequence of this paradox are complex: while there exists a useful correlation between cellular types, treatment and prognosis, numerous problems and difficulties persist. The most serious of them concems the "unclassified leukemias" which are the reason for this reunion.
Unclassifiable Leukemias
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Author : M Bessis
language : en
Publisher:
Release Date : 1975-11-01
Unclassifiable Leukemias written by M Bessis and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975-11-01 with categories.
Immunological Diagnosis Of Leukemias And Lymphomas
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Author : S. Thierfelder
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Immunological Diagnosis Of Leukemias And Lymphomas written by S. Thierfelder and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This two-and-a-half-day symposium has concentrated on main aspects of the rapidly expanding field ofleukocyte markers in hematology. While leukemias are already being 'phenotyped' routinely in clinical centers, continued research on the developmental sta ge of cells and cell membranes, expanding into a malignant clone, permits new snap shots on hemopoietic differentiation. Thus the discovery of leukemia-associated anti gens, which so far have not been found on subpopulations of normal cells, has greatly stimulated the discussion on 'differentiation antigens versus tumor antigens'. The proceedings reflect the considerable success which has been achieved very re cently in the classification of hemoblastomas. Consequently the number of leukemias which are unclassifiable by immunological methods have dwindled down to a small mi nority. New facts give rise to new questions. By including the main points of the discussions in the proceedings, we wanted to give the reader an opportunity to get an impression of the questions and conclusions raised and drawn by the participants on the basis of new - and frequently still unpublished - data. The editors thank both the contributors to this symposium, who made it a successful meeting and submitted their manuscripts punctually, and the publishers, who have provided a volume of high quality in good time. They are also grateful for the valuable cooperation from numerous colleages at the Institut fUr Hamatologie.
Acute Leukemias
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Author : Pier Paolo Piccaluga
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-03-24
Acute Leukemias written by Pier Paolo Piccaluga and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-24 with Medical categories.
Written by expert research teams, this book describes different aspects of both acute myeloid and acute lymphocytic leukemia, specifically their pathobiology, classification/diagnosis, and treatment. Chapters highlight current research as well as the gold standards for diagnosis and treatment of these diseases, examining recent advances in personalized approaches to acute leukemia.
Blood Smears Reinterpreted
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Author : Marcel Bessis
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Blood Smears Reinterpreted written by Marcel Bessis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The translation of Blood Smears Reinterpreted was begun when the French original was still undergoing revisions. I was accorded the oppor tunity to question any statement or turn of phrase that was unclear to me or appeared liable to misinterpretation. It is my hope that as a result, ambiguities-particularly those inherent in differences between American and Eu ropean usage-have been removed and that I have at least ap proached the ultimate goal of any translation: to reflect the author's intention accurately while remaining as readable as the original. Beyond the role of translator, I was encouraged to assume the role of critic. As a result, some pages or even single sentences were hotly debated, sometimes for hours, as Marcel Bessis insisted that any inter pretations on which we could not agree should be so indicated. In fact our discussion invariably ended in agreement, though they led to changes of a sentence here or a word there and, on occasion, to the addition of a footnote or a brief paragraph.
Dynamic Morphology Of Leukemia Cells
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Author : H. Felix
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Dynamic Morphology Of Leukemia Cells written by H. Felix and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Dynamic Morphology is the attempt to correlate surface architec ture and shape of fixed cells, as visualized by scanning electron microscopy (SEM), with the behavior of living cells, recorded by microcinematography (MCM). If SEM and MCM are used concurrently for the analysis of cell populations, a dynamic inter pretation of SEM photographs is only valid if the experimental conditions are identical for the two techniques. This is achieved by allowing the cells to settle on a glass surface where they remain long enough to perform their various activities under conditions identical for both techniques (for technical details see Methodology). The analysis of a population necessitates the study of a large number of cells. This prerequisite is met by operating the scanning electron micro scope at low levels of magnification, and by using culture chambers for cinematography. It can be argued that the examina tion of attached cells excludes a complete SEM survey of a population, as cells not adhering from the outset or becoming detached during the different preparatory steps are lost. For this, cinematography proved to be a reliable control: All cell types recognized in time-lapse films were also seen in scanning electron (SE) micrographs. Another, and more general, objection to a dynamic interpretation concerns the artificiality of cellular behavior on glass. This is true, but does not invalidate compara tive studies making use of this substrate.
Atlas Of Blood Cells In Health And Disease
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Author : Marguerite Candler Ballard
language : en
Publisher:
Release Date : 1987
Atlas Of Blood Cells In Health And Disease written by Marguerite Candler Ballard and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Blood categories.
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1989
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medicine categories.
French Studies In The Philosophy Of Science
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Author : Anastasios Brenner
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-04-14
French Studies In The Philosophy Of Science written by Anastasios Brenner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-14 with Science categories.
Having examined previous volumes of the Boston Studies series devoted to different countries, and having discussed the best way to present contemporary research in France, we have arrived at a careful selection of 15 participants, including the organizers. Our aim is to bring together philosophers and practicing scientist from the major institutions of the country, both universities and research centers. The areas of research represented here cover a wide spectrum of sciences, from mathematics and physics to the life sciences, as well as linguistics and economics. This selection is a showcase of French philosophy of science, illustrating the different methods employed: logico-linguistic analysis, rational reconstruction and historical inquiry. These participants have the ability to relate their research both to the French tradition and current discussions on the international scene. Also included is a substantial historical introduction, explaining the development of philosophy of science in France, the various schools of thought and methods as well as the major concepts and their significance.
Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date :
Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medicine categories.
First multi-year cumulation covers six years: 1965-70.