Understanding The Interplay Between The Tumor Immune Microenvironment And Genetic Alterations In Thoracic Malignancies

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Understanding The Interplay Between The Tumor Immune Microenvironment And Genetic Alterations In Thoracic Malignancies
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Author : Giulia Pasello
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-28
Understanding The Interplay Between The Tumor Immune Microenvironment And Genetic Alterations In Thoracic Malignancies written by Giulia Pasello and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-28 with Medical categories.
Application Of Multi Omics Analysis In Thoracic Cancer Immunotherapy
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Author : Attila Szöllősi
language : en
Publisher: Frontiers Media SA
Release Date : 2024-11-19
Application Of Multi Omics Analysis In Thoracic Cancer Immunotherapy written by Attila Szöllősi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-19 with Medical categories.
Based on statistical data provided by the World Health Organization, cancer is widely acknowledged as the foremost contributor to global mortality and persists as a significant concern in the contemporary era. In recent times, immunotherapy has been demonstrated as an efficacious approach in diverse advanced solid tumors, especially in thoracic tumors, consequently emerging as a prominent area of focus in the investigation of antitumor pharmaceuticals. The utilization of immunotherapy directed towards programmed death ligand-1 (PD-L1) and programmed cell death protein-1 (PD-1) has emerged as a valid approach, resulting in substantial enhancements in both disease-free and overall survival rates among cancer patients. Moreover, applications of multi-omics analyses in thoracic tumors have made great progress. However, it also ushered in new challenges. Certain subtypes of thoracic cancer have been identified as immune-quiescent tumors, indicating that only a limited number of patients would derive benefits from immunotherapy while also experiencing a high incidence of severe adverse events. Besides, multi-omics analyses reveal patterns of drug resistance and relapse in the treatment of thoracic tumors, which help us identify the molecular mechanisms that lead to drug resistance and provide clues for overcoming it. Meanwhile, exploring the role of the tumor microenvironment (TME) in the development and metastasis of thoracic tumors can help us better understand the potential mechanisms of tumor spread and find approaches to intervene.
Aacr 2018 Proceedings Abstracts 3028 5930
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Author : American Association for Cancer Research
language : en
Publisher: CTI Meeting Technology
Release Date : 2018-04-10
Aacr 2018 Proceedings Abstracts 3028 5930 written by American Association for Cancer Research and has been published by CTI Meeting Technology this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-10 with categories.
Iaslc Thoracic Oncology E Book
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Author : Harvey Pass
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-04-21
Iaslc Thoracic Oncology E Book written by Harvey Pass and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-21 with Medical categories.
Global experts, in conjunction with the International Association for the Study of Lung Cancer, bring you up to date with today's best approaches to lung cancer diagnosis, treatment, and follow-up. IASLC Thoracic Oncology, 2nd Edition, keeps you abreast of the entire scope of this fast-changing field, from epidemiology to diagnosis to treatment to advocacy. Written in a straightforward, practical style for the busy clinician, this comprehensive, multidisciplinary title is a must-have for anyone involved in the care of patients with lung cancer and other thoracic malignancies. - Offers practical, relevant coverage of basic science, epidemiology, pulmonology, medical and radiation oncology, surgery, pathology, palliative care, nursing, and advocacy. - Provides authoritative guidance from the IASLC – the only global organization dedicated to the study of lung cancer. - Includes new content on molecular testing, immunotherapy, early detection, staging and the IASLC staging system, surgical resection for stage I and stage II lung cancer, and stem cells in lung cancer. - Features a new full-color design throughout, as well as updated diagnostic algorithms. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.
How To Select Patients With Thoracic Cancers For Immunotherapy Chemotherapy Or Immunotherapy Angiogenesis Inhibitor Combinations
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Author : Weimin Mao
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-28
How To Select Patients With Thoracic Cancers For Immunotherapy Chemotherapy Or Immunotherapy Angiogenesis Inhibitor Combinations written by Weimin Mao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-28 with Medical categories.
Handbook Of Lung Cancer And Other Thoracic Malignancies
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Author : Gregory P. Kalemkerian, MD
language : en
Publisher: Springer Publishing Company
Release Date : 2016-11-28
Handbook Of Lung Cancer And Other Thoracic Malignancies written by Gregory P. Kalemkerian, MD and has been published by Springer Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-28 with Medical categories.
In many ways, the field of lung cancer research is leading the way in personalized oncologic care, with numerous new treatment strategies moving from clinical trials to standard clinical practice within the past 10 years; and, there are no indications of bench-to-bedside innovations slowing down. Handbook of Thoracic Oncology is a practical guide to the multidisciplinary management of patients with lung cancer and other thoracic malignancies. The content highlights the applications of both conventional and novel treatment strategies to the care of real-life patients with lung cancer. Unlike many oncology textbooks that exhaustively list studies of historical or failed approaches, this handbook focuses on the application of practical, current management options to specific patient subsets and the data that specifically support these strategies. The format is open and readable with bulleted points presenting overall treatment guidelines as well as more nuanced applications of these treatments to individual patient groups. The clear focus of this book is on the question that all oncologists ask themselves every day, “How do I take care of this person sitting in front of me?” This handbook is an indispensable guide for all oncologists and practitioners who regularly care for lung cancer patients and those suffering from mesothelioma, thymic tumors, and pulmonary neuro-endocrine tumors. Features: Delivers the need-to-know points of lung cancer screening, diagnosis and staging, and appropriate multidisciplinary management for all major thoracic malignancies Provides clinical pearls and treatment recommendations for patients who don’t ‘fit’ the standard guidelines Includes specific coverage on Management of Elderly and High-Risk Patients Prepares physicians to notice and eliminate common errors in clinical practice when managing patients with lung cancer and other thoracic tumors
Molecular Diagnosis And Targeting For Thoracic And Gastrointestinal Malignancy
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Author : Yutaka Shimada
language : en
Publisher: Springer
Release Date : 2017-11-29
Molecular Diagnosis And Targeting For Thoracic And Gastrointestinal Malignancy written by Yutaka Shimada and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-29 with Medical categories.
This volume focuses on the clinical applications of molecular diagnosis and targeted therapy from the viewpoint of oncologists specializing in specific organs. In addition, it discusses the role of molecular diagnosis and targeted therapy in the course of surgical treatment. Recent, rapid advances in molecular biology have shed new light on the mechanisms of cancer progression, and molecularly targeted drugs have been used to treat a variety of malignant diseases. For the diagnosis and precise treatment of cancer, analysis of the molecular background of the tumor is indispensable. However, there are both tumor-specific and comprehensive mechanisms involved in these processes. Accordingly, a firm grasp of molecular diagnosis and targeted therapies for different tumors is vital for clinicians and basic researchers alike. This book provides essential information and the latest findings on molecular diagnosis and targeted therapy for thoracic and gastrointestinal malignancies. Though primarily intended for clinical and basic oncologists, it also offers a useful guide for clinicians who are interested in this field and are considering getting started in molecular diagnosis and targeted therapy.
Mesothelioma Heterogeneity Potential Mechanisms
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Author : Emanuela Felley-Bosco
language : en
Publisher: MDPI
Release Date : 2019-01-11
Mesothelioma Heterogeneity Potential Mechanisms written by Emanuela Felley-Bosco and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-11 with Science categories.
This book is a printed edition of the Special Issue "Mesothelioma Heterogeneity: Potential Mechanisms" that was published in IJMS
Malignant Pleural Mesothelioma An Issue Of Thoracic Surgery Clinics E Book
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Author : Bryan M. Burt
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-11-28
Malignant Pleural Mesothelioma An Issue Of Thoracic Surgery Clinics E Book written by Bryan M. Burt and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-28 with Medical categories.
This issue of Thoracic Surgery Clinics, guest edited by Dr. Bryan M. Burt, is devoted to Malignant Pleural Mesothelioma. Dr. Burt has assembled expert authors to review the following topics: Biomarkers for the Diagnosis and Monitoring of Malignant Pleural Mesothelioma; Taken Together: Effective Multimodal Approaches for Malignant Pleural Mesothelioma; Pleurectomy/Decortication for Malignant Pleural Mesothelioma; Preoperative Identification of Benefit from Surgery for Malignant Pleural Mesothelioma; The Role of Extrapleural Pneumonectomy in Malignant Pleural Mesothelioma; The Molecular Basis of Malignant Pleural Mesothelioma; Radiation Therapy for Malignant Pleural Mesothelioma; The Staging of Malignant Pleural Mesothelioma; Intraoperative Adjuncts for Malignant Pleural Mesothelioma: The Fourth Dimension; The Pathology of Malignant Pleural Mesothelioma; and more!
New Trends In Early Stage Lung Cancer Presenting As Ground Glass Opacities Clinical Pathological And Molecular Aspects
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Author : Chen Chen
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-17
New Trends In Early Stage Lung Cancer Presenting As Ground Glass Opacities Clinical Pathological And Molecular Aspects written by Chen Chen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-17 with Medical categories.