Understanding The Materno Fetal Interface During Microbial Infections

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Understanding The Materno Fetal Interface During Microbial Infections
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Author : Demba Sarr
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-11
Understanding The Materno Fetal Interface During Microbial Infections written by Demba Sarr and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-11 with Science categories.
Pregnancy is a physiologically and immunologically challenging health state. Immunological and physiological changes throughout the course of pregnancy make pregnant women usually susceptible to infection with microbial agents. Infections with pathogens during pregnancy can have devastating consequences to both the fetus and his/her mother. These infections are linked with adverse pregnancy outcomes. Infections with parasites, viruses, or bacteria can be associated with maternal anemia, abortion, intrauterine growth retardation, preterm delivery, fetal morbidity and high risk of mortality during the first years of life. Despite these significant consequences and complications associated with infections by microbial pathogens during the course of gestation, very little is known about the underlying mechanisms of the pathogenesis and immunopathology of infections during pregnancy. The Research Topic proposed here in, will focus on microbial infections during pregnancy. Studies and review papers addressing the pregnant host/fetus/pathogen interactions, the host/fetus immunological response against infections during gestation, trans-placental transfer of infections during pregnancy are welcome. Topics related to model systems used to mirror the biology in human, the pathogenesis and molecular pathways as well as the mechanisms of the disease at the maternofetal interface including the placenta, the amniotic fluid, and the fetal membranes will be considered making the scope and interest of the topic relatively broad. There is a growing number of pathogens associated with pregnancy. In most cases, women are more susceptible to infections with these pathogens when they become pregnant in comparison to their non-pregnant counterparts. Unfortunately, vertical transmission occurs in most cases but the underlying mechanisms are still unknown. The placenta has always been considered as a barrier against congenital infections but studies have indicated that microbial pathogens breach this barrier. The amniotic fluid, and the fetal membranes are also important components of vertical transmission because of their non-sterile state even in most healthy pregnancies. During pregnancy, infections by malaria or toxoplasmosis as well as other viral or bacterial pathogens lead to an uncontrolled inflammatory response recognized as a significant cause for preterm delivery and intra uterine growth retardation leading to low birth weight, a risk factor to infant morbidity and mortality. To successfully prevent, treat, eradicate or educate about microbial infections during pregnancy, we must understand the molecular mechanisms by which they cause poor birth outcomes including how vertical transmission occurs at the maternofetal interface.
Obstetrics Normal And Problem Pregnancies E Book
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Author : Mark B. Landon
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-02-17
Obstetrics Normal And Problem Pregnancies E Book written by Mark B. Landon and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-17 with Medical categories.
Highly readable, well-illustrated, and easy to understand, Gabbe's Obstetrics: Normal and Problem Pregnancies is an ideal day-to-day reference or study tool for residents and clinicians. This 8th Edition of this bestselling text offers fast access to evidence-based, comprehensive information, now fully revised with substantial content updates, new and improved illustrations, and a new, international editorial team that continues the tradition of excellence established by Dr. Steven Gabbe. - Puts the latest knowledge in this complex specialty at your fingertips, allowing you to quickly access the information you need to treat patients, participate knowledgably on rounds, and perform well on exams. - Contains at-a-glance features such as key points boxes, bolded text, chapter summaries and conclusions, key abbreviations boxes, and quick-reference tables, management and treatment algorithms, and bulleted lists throughout. - Features detailed illustrations from cover to cover—many new and improved—including more than 100 ultrasound images that provide an important resource for normal and abnormal fetal anatomy. - Covers key topics such as prevention of maternal mortality, diabetes in pregnancy, obesity in pregnancy, vaginal birth after cesarean section, and antepartum fetal evaluation. - Provides access to 11 videos that enhance learning in areas such as cesarean delivery and operative vaginal delivery. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices
Covid 19 And Perinatology
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Author : Daniele De Luca
language : en
Publisher: Springer Nature
Release Date : 2023-06-21
Covid 19 And Perinatology written by Daniele De Luca and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-21 with Medical categories.
COVID19 pandemics has had profound consequences on public health and has represented a challenge for several medical specialties. Despite this was underestimated at the beginning of the outbreak, COVID19 is actually impacting on women and children health, as well. The consequences in this field are multifaceted and complex as they span from the occurrence of COVID19 in pregnant patients, to the possibility of SARS-CoV-2 mother-to-child transmission, the occurrence of neonatal COVID and pediatric sequelae. COVID19 and the related public health measures may also have important consequences on psychological well-being and organization of perinatal care as well as they raise relevant ethical issues. All these aspects were at risk to be forgotten within the many others highlighted by the pandemics but are important both for individual care and also from a political point of view and the organization of care. There is a large demand of high-quality education, information and training in this field and we answered that by organising the COVID19 in Pregnancy and Childhood Days: this book represents the hard legacy of this event with the contribution of key opinion leaders in all the aforementioned specialties. The book is answering a clear need and is directed to: 1) obstetricians, 2) neonatologists, 3) pediatricians, 3) public health specialists, 4) adult critical care physicians, 5) infectious disease specialists, 5) psychologists. Last but not least, the informations resumed in the book are going to be useful for healthcare authorities to program perinatal care and improve it. The book will also serve as textbook for post-graduate courses and academic review resuming the state-of-the art knowledge on this area. Thus, it will be cited and used by researchers in the field: this is not a secondary characteristics as it may be quite difficult to find relevant informations, in this infodemic era, using the usual channels and databases.
Fetal And Neonatal Physiology E Book
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Author : Richard Polin
language : en
Publisher: Elsevier Health Sciences
Release Date : 2021-07-29
Fetal And Neonatal Physiology E Book written by Richard Polin and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-29 with Medical categories.
Offering the comprehensive, authoritative information needed for effective diagnosis, treatment, and management of sick and premature infants, Fetal and Neonatal Physiology, 6th Edition, is an invaluable resource for board review, clinical rounds, scientific research, and day-to-day practice. This trusted two-volume text synthesizes recent advances in the field into definitive guidance for today's busy practitioner, focusing on the basic science needed for exam preparation and key information required for full-time practice. It stands alone as the most complete text available in this complex and fast-changing field, yet is easy to use for everyday application. - Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants. - Contains new chapters on Pathophysiology of Genetic Neonatal Disease, Genetic Variants and Neonatal Disease, and Developmental Biology of Lung Stem Cells, as well as significantly revised chapters on Cellular Mechanisms of Neonatal Brain Injury, Neuroprotective Therapeutic Hypothermia, Enteric Nervous System Development and Gastrointestinal Motility, and Physiology of Twin-Twin Transfusion. - Features 1,000 full-color diagrams, graphs and anatomic illustrations, 170+ chapters, and more than 350 global contributors. - Includes chapters devoted to clinical correlation that help explain the implications of fetal and neonatal physiology, as well as clinical applications boxes throughout. - Provides summary boxes at the end of each chapter and extensive cross-referencing between chapters for quick reference and review. - Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more.
Translational Virology In Pregnancy
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Author : Kristina M. Adams Waldorf
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-05
Translational Virology In Pregnancy written by Kristina M. Adams Waldorf and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-05 with Medical categories.
Viral pandemics, such as influenza A virus H1N1, Zika virus, and most recently SARS-CoV-2 are becoming more common. Depending on the virus, infection during pregnancy may impart risk for more severe maternal disease, preterm birth, preeclampsia, stillbirth or congenital anomalies. The maternal, placental and fetal immune response is essential for viral clearance. However, viral evasion of host immunity may lead to persistent viremia, placental infection and vertical transmission. There is an urgent need to understand the impact of a wide array of viruses on maternal-fetal immunity, maternal health, pregnancy outcomes and fetal development.
Innate Immunity In Normal And Adverse Pregnancy
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Author : Jean F. Regal
language : en
Publisher: Frontiers Media SA
Release Date : 2021-03-25
Innate Immunity In Normal And Adverse Pregnancy written by Jean F. Regal and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-25 with Medical categories.
Myles Textbook For Obstetrics And Gynaecology Nursing I And Ii Two Volume Set 17e Sae 1e E Book
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Author : Manju Chhugani
language : en
Publisher: Elsevier Health Sciences
Release Date : 2024-05-20
Myles Textbook For Obstetrics And Gynaecology Nursing I And Ii Two Volume Set 17e Sae 1e E Book written by Manju Chhugani and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-20 with Medical categories.
Myles Textbook for Obstetrics and Gynaecology Nursing I and II (Two Volume Set)_17e_SAE – 1E - E-Book
Congenital And Perinatal Infections
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Author : Jennifer S. Read
language : en
Publisher: Oxford University Press
Release Date : 2018
Congenital And Perinatal Infections written by Jennifer S. Read and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Medical categories.
CONGENITAL AND PERINATAL INFECTIONS provides a concise and clinically-oriented primer on the congenital and perinatal infections likely to present in clinical practice. Written with the busy clinician in mind, it combines easy accessibility with state-of-the-art information on the epidemiology, pathogenesis, clinical manifestations, diagnosis, treatment, and prevention of congenital and perinatal infections. Eschewing the notion that congenital and perinatal infections only encompass agents from the TORCH group of pathogens, this volume offers comprehensive information on the spectrum of viral, bacterial, and parasitic infections that can manifest in mother or child. Combined with its brevity and emphasis on clinical management, CONGENITAL AND PERINATAL INFECTIONS is a definitive new guide to understanding this challenging group of infections.
Maternal Fetal Neonatal Physiology4
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Author : Susan Tucker Blackburn
language : en
Publisher: Elsevier Health Sciences
Release Date : 2012-01-01
Maternal Fetal Neonatal Physiology4 written by Susan Tucker Blackburn and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-01 with Medical categories.
Provide the best care possible with expert insight and clinically relevant coverage of the physiologic changes that occur throughout all major periods of the perinatal experience - prenatal, intrapartum, postpartum, and neonatal. Maternal, Fetal & Neonatal Physiology: A Clinical Perspective, 4th Edition gives you a solid foundation for assessment and therapeutic interventions, featuring an emphasis on the evolving interrelationships between mother, fetus, and neonate and adaptations of preterm and term infants to the extrauterine environment. Solid coverage of the physiologic bases for assessment and therapeutic interventions make this an ideal resource for advanced practice. Synthesis of the latest research studies and evidence-based practice provides vital data on normal physiologic changes during the antepartum, intrapartum and postpartum periods; anatomic and functional development of the fetus; and developmental physiology of preterm and term neonates. Pharmacology tables offer quick access to key pharmacology information and drug effects with clinical examples. Coverage of pathophysiology and interventions for the pregnant woman, fetus, and newborn for selected abnormal events provides a solid understanding of physiologic adaptations and developmental physiology relating to major body systems and metabolic processes.Comprehensive tables, diagrams, and illustrations highlight important concepts and summarize key information Thoroughly updated content offers the very latest evidence-based information, contemporary research, and clinical developments related to maternal, fetal, and neonatal physiology. New coverage on the late pre-term infant provides the most current practice guidelines to promote quality care. Expanded discussions of reproductive processes reflect cutting-edge research and the clinical implications of physiologic and genetic effects brought to bear from both the female and the male. Extensive and reliable web sources allow for further study or checking for updated information. New NICHD standard definitions on fetal monitoring enable you to identify fetal heart rate patterns using standardized nomenclature.
Creasy And Resnik S Maternal Fetal Medicine Principles And Practice E Book
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Author : Charles J. Lockwood
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-08-07
Creasy And Resnik S Maternal Fetal Medicine Principles And Practice E Book written by Charles J. Lockwood and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-07 with Medical categories.
Long recognized as the authoritative leader in the field, Creasy and Resnik's Maternal-Fetal Medicine, 8th Edition, continues to provide the latest evidence-based guidelines for obstetric and neonatal management, helping you minimize complications and offer patients the best possible care. Written by renowned experts in obstetrics, gynecology, and perinatology, this comprehensive resource has been thoroughly updated and reflects new information in every area, including recent tremendous advances in genetics, imaging, and more. Focuses on complicated obstetric issues, highlighting the most commonly encountered anomalies and providing clear guidelines for obstetric and neonatal management. Offers comprehensive updates on rapidly changing topics, including a completely revised section on genetics and genetic technology for prenatal diagnoses, as well as an expanded imaging section on abdominal, urogenital, and skeletal imaging. Includes four new chapters: Molecular Genetic Technology, MRI in Obstetrical Imaging, Obesity in Pregnancy, and Pregnancy as a Window to Future Health. Features numerous flow charts for quick access to diagnosis and treatment protocols and to clarify complex material. Presents the knowledge and expertise of new editors Dr. Joshua Copel, an expert in the field of fetal therapy who has pioneered new diagnostic techniques for unborn patients and their mothers, and Dr. Robert Silver, a leader in the maternal-fetal medicine community.