Unravelling Cancer Signaling Pathways A Multidisciplinary Approach


Unravelling Cancer Signaling Pathways A Multidisciplinary Approach
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Unravelling Cancer Signaling Pathways A Multidisciplinary Approach


Unravelling Cancer Signaling Pathways A Multidisciplinary Approach
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Author : Kakoli Bose
language : en
Publisher: Springer Nature
Release Date : 2019-11-25

Unravelling Cancer Signaling Pathways A Multidisciplinary Approach written by Kakoli Bose and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-25 with Medical categories.


Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.



Pharmacotherapeutic Botanicals For Cancer Chemoprevention


Pharmacotherapeutic Botanicals For Cancer Chemoprevention
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Author : Manish Kumar
language : en
Publisher: Springer Nature
Release Date : 2020-07-20

Pharmacotherapeutic Botanicals For Cancer Chemoprevention written by Manish Kumar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-20 with Medical categories.


The book presents a comprehensive and up-to-date overview of phytochemicals as efficient cancer therapeutics. Over the last few decades there has been a paradigm shift from conventional cancer therapeutic approaches to alternative and complementary medicinal approaches especially using phytoconstituents from natural products. As such, the book provides an in-depth understanding of phytochemicals targeting diverse signaling pathways involved in cancer along with the evaluation of the cancer modulatory effects of phytochemicals. It also highlights the potential modulatory effect of single nucleotide polymorphisms (SNPs) on the cancer-associated cellular pathways and their interactions with the phytochemicals. Further, it analyzes the drug delivery methods, bioavailability of active components of botanicals, and toxicity of phytochemicals. Lastly, the book elucidates the 3D cell culture and animal models systems to analyze the beneficial effects of phytochemicals in cancer.



Protein Lipidation In Health And Disease


Protein Lipidation In Health And Disease
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Author : Rebeca M. Mejias Estevez
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-15

Protein Lipidation In Health And Disease written by Rebeca M. Mejias Estevez and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-15 with Science categories.




Protein Interactions


Protein Interactions
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Author : Volkhard Helms
language : en
Publisher: John Wiley & Sons
Release Date : 2022-11-08

Protein Interactions written by Volkhard Helms and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-08 with Science categories.


Protein Interactions A fundamental guide to the burgeoning field of protein interactions From enzymes to transcription factors to cell membrane receptors, proteins are at the heart of biological cell function. Virtually all cellular processes are governed by their interactions, with one another, with cell bodies, with DNA, or with small molecules. The systematic study of these interactions is called Interactomics, and research within this new field promises to shape the future of molecular cell biology. Protein Interactions goes beyond any existing guide to protein interactions, presenting the first truly comprehensive overview of the field. Edited by two leading scholars in the field of protein bioinformatics, this book covers all known categories of protein interaction, stable as well as transient, as well as the effect of mutations and post-translational modifications on the interaction behavior. Protein Interactions readers will also find: Introductory chapters on protein structure, conformational dynamics, and protein-protein binding interfaces A data-driven approach incorporating machine learning and integrating experimental data into computational models An outlook on the current challenges in the field and suggestions for future research Protein Interactions will serve as a fundamental resource for novice researchers who want a systematic introduction to interactomics, as well as for experienced cell biologists and bioinformaticians who want to gain an edge in this exciting new field.



Multidisciplinary Approach For Colorectal Cancer


Multidisciplinary Approach For Colorectal Cancer
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Author : Keun-Yeong Jeong
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-12-18

Multidisciplinary Approach For Colorectal Cancer written by Keun-Yeong Jeong and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-18 with Medical categories.


A multidisciplinary understanding of the various processes leading to colorectal cancer progression is important for creating promising methods of therapy. Therefore it is necessary to scrutinize the progression of cancer and the therapeutic process through various academic theories. This book examines colorectal cancer - its prevention, pathogenesis, and treatment - through a multidisciplinary lens in an effort to advance understanding of the disease and improve therapeutic efficacy.



Multidisciplinary Approaches In Exploring Cancer Heterogeneity Tme And Therapy Resistance Perspectives For Systems Medicine


Multidisciplinary Approaches In Exploring Cancer Heterogeneity Tme And Therapy Resistance Perspectives For Systems Medicine
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Author : Brigitte M. Pützer
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-07

Multidisciplinary Approaches In Exploring Cancer Heterogeneity Tme And Therapy Resistance Perspectives For Systems Medicine written by Brigitte M. Pützer and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-07 with Science categories.




Optimizing Well Being In Hypopharyngeal Cancer A Comprehensive Guide For Patients And Caregivers


Optimizing Well Being In Hypopharyngeal Cancer A Comprehensive Guide For Patients And Caregivers
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Author : Dr. Spineanu Eugenia
language : en
Publisher: Dr. Spineanu Eugenia
Release Date : 2024-03-03

Optimizing Well Being In Hypopharyngeal Cancer A Comprehensive Guide For Patients And Caregivers written by Dr. Spineanu Eugenia and has been published by Dr. Spineanu Eugenia this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-03 with Medical categories.


Discover 'Optimizing Well-Being in Hypopharyngeal Cancer,' a comprehensive guide tailored to patients and caregivers navigating the challenges of this condition. Written by medical experts, this treatise offers a holistic approach to managing hypopharyngeal cancer, providing invaluable insights into its medical intricacies, anatomy, risk factors, and pathogenesis. Readers will delve into the world of hypopharyngeal cancer, gaining a profound understanding of its genetic and epigenetic alterations, the role of oncogenes and tumor suppressors, and the intricate cell signaling pathways involved. Explore the latest research on biomarkers, metabolism, and immunological aspects, empowering you with knowledge to make informed decisions about your treatment journey. With chapters dedicated to surgical techniques, radiation therapy, chemotherapy, targeted therapies, immunotherapy, and palliative care, this treatise equips you with a comprehensive toolkit to combat hypopharyngeal cancer effectively. Dive into the world of cutting-edge treatments and emerging therapies, guided by the expertise of medical professionals. Additionally, this guide delves into complementary and alternative therapies, offering insights into their safe integration alongside conventional treatments. Explore the benefits of mind-body practices, social support, and coping strategies that enhance your emotional and psychological well-being. As you navigate your cancer journey, this treatise provides crucial guidance on survivorship, quality of life assessment, and holistic approaches to well-being. Empower yourself with knowledge, resilience, and the support needed to optimize your well-being in the face of hypopharyngeal cancer. 'Optimizing Well-Being in Hypopharyngeal Cancer' is your indispensable companion on the path to recovery and a resource you can trust. Start your journey to well-being today, and let this guide be your beacon of hope and healing.



Targeted Therapies For Solid Tumors


Targeted Therapies For Solid Tumors
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Author : Antonio Russo
language : en
Publisher: Humana Press
Release Date : 2015-03-11

Targeted Therapies For Solid Tumors written by Antonio Russo and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-11 with Medical categories.


This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical development of new molecularly targeted agents, the use of biomarkers as prognostic, predictive and surrogate endpoints, and the evaluation of tumor response and specific malignancies treated with targeted agents. The book also covers some of the newest developments in cancer therapy that are not adequately covered by any current available literature. Written by recognized experts in the field, Targeted Therapies for Solid Tumors: A Handbook for Moving Toward New Frontiers in Cancer Treatment provides a unique and valuable resource in the field of molecular oncology, both for those currently in training, and for those already in clinical or research practice.



Epithelial Mesenchymal Plasticity In Cancer Metastasis


Epithelial Mesenchymal Plasticity In Cancer Metastasis
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Author : Mohit Kumar Jolly
language : en
Publisher: MDPI
Release Date : 2020-12-29

Epithelial Mesenchymal Plasticity In Cancer Metastasis written by Mohit Kumar Jolly and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-29 with Medical categories.


Recent studies have highlighted that epithelial-mesenchymal transition (EMT) is not only about cell migration and invasion, but it can also govern many other important elements such as immunosuppression, metabolic reprogramming, senescence-associated secretory phenotype (SASP), stem cell properties, therapy resistance, and tumor microenvironment interactions. With the on-going debate about the requirement of EMT for cancer metastasis, an emerging focus on intermediate states of EMT and its reverse process mesenchymal-epithelial transition (MET) offer new ideas for metastatic requirements and the dynamics of EMT/MET during the entire metastatic cascade. Therefore, we would like to initiate discussions on viewing EMT and its downstream signaling networks as a fulcrum of cellular plasticity, and a facilitator of the adaptive responses of cancer cells to distant organ microenvironments and various therapeutic assaults. We hereby invite scientists who have prominently contributed to this field, and whose valuable insights have led to the appreciation of epithelial-mesenchymal plasticity as a more comprehensive mediator of the adaptive response of cancer cells, with huge implications in metastasis, drug resistance, tumor relapse, and patient survival.



Animal Welfare In Animal Agriculture


Animal Welfare In Animal Agriculture
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Author : Wilson G. Pond
language : en
Publisher: CRC Press
Release Date : 2011-11-23

Animal Welfare In Animal Agriculture written by Wilson G. Pond and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-23 with Medical categories.


What constitutes animal welfare? With animals being used for companionship, service, research, food, fiber, and by-products, animal welfare is a topic of great interest and importance to society. As the world's population continues to increase, a major challenge for society is the maintenance of a strong and viable food system, which is linked to t