Unveiling Biomarkers And Mechanisms In The Tumor Immune Nexus
DOWNLOAD
Download Unveiling Biomarkers And Mechanisms In The Tumor Immune Nexus PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Unveiling Biomarkers And Mechanisms In The Tumor Immune Nexus book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Unveiling Biomarkers And Mechanisms In The Tumor Immune Nexus
DOWNLOAD
Author : Wantao Wu
language : en
Publisher: Frontiers Media SA
Release Date : 2025-03-20
Unveiling Biomarkers And Mechanisms In The Tumor Immune Nexus written by Wantao Wu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-20 with Medical categories.
The interplay between cancer cells and the immune system is a critical area of research, with recent advancements highlighting the potential of immunotherapy in offering durable responses across various cancer types. Immune checkpoint inhibitors, in particular, have emerged as a cornerstone of cancer therapy, transforming patient outcomes. However, the heterogeneity of tumor-immune interactions poses significant challenges, with a considerable fraction of patients not responding to such treatments. This underscores the urgent need for a deeper understanding of the molecular and cellular underpinnings of these interactions, to harness the full potential of immunotherapy. This Research Topic aims to address the complex landscape of tumor-immune interactions, focusing on identifying and leveraging novel biomarkers and mechanisms that can predict and enhance the efficacy of immunotherapy. Given the pivotal role of the immune system in controlling and eradicating cancer, understanding these interactions at a granular level could lead to more personalized and effective treatment strategies. Recent advances in technologies such as next-generation sequencing, single-cell RNA sequencing, and mass cytometry have opened new avenues for dissecting the complexity of the tumor microenvironment and immune evasion strategies. This collection seeks to compile cutting-edge research that employs these technologies to uncover new biomarkers, understand resistance mechanisms, and identify potential therapeutic targets within the immune contexture of tumors. By bridging gaps in knowledge and fostering innovation, this topic aims to propel the field towards more predictive and responsive immunotherapy approaches.
Novel Biomarkers And Big Data Based Biomedical Studies In Cancer Diagnosis And Management
DOWNLOAD
Author : Lin Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2025-06-05
Novel Biomarkers And Big Data Based Biomedical Studies In Cancer Diagnosis And Management written by Lin Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-05 with Science categories.
Cancer is a multifaceted disease that can elude the natural defense mechanisms of the immune system. Due to the heterogeneity and complexity of cancer, the technical methods used for pre-treatment evaluation, prediction of treatment efficacy, and prognosis analysis still require further research. Immunotherapy has shown immense potential in the treatment of numerous types of cancer. Cancer immunotherapy aims to eliminate malignant cells based on their antigen composition and tumor-associated antigens. PD-1 and PD-L1 are crucial targets for cancer immunotherapy. Although various inflammatory factors and immune markers have been identified to aid in selecting appropriate treatment (chemotherapy or immunotherapy), monitoring treatment efficacy, and predicting prognosis, the combination of different markers in predictive models performs better than a single marker in enhancing the accuracy of treatment efficacy and clinical judgments. In the context of precise cancer treatment, novel diagnoses, predictive factors, and predictive models are essential for better comprehension of cancer treatment and prognosis. The amalgamation of big data and artificial intelligence has been widely utilized in various cancer fields, including basic cancer research, particularly in molecular biological mechanisms, metabolic reprogramming, tumor biology, and clinical transformation research (such as cancer prediction, early diagnosis methods, and development of new treatment methods). The systematic and objective data provided by big data and artificial intelligence can guide diagnosis, optimize clinical treatment decisions, and have a far-reaching impact on clinical transformation. This research topic aims to explore novel biomarkers and predictive models that predict prognosis, treatment efficacy, and toxic side effects in cancer patients. We welcome submissions including, but not limited to: (1) Clinical research investigating novel biomarkers and their comprehensive predictive models for cancer treatment (including chemotherapy, radiation therapy, targeted therapy, and immunotherapy) and prognosis. (2) Original research investigating inflammatory and immune factors associated with various types of cancer, particularly breast and gastrointestinal cancer. (3) Reviews and meta-analyses of effective biomarkers and predictive models in cancer treatment and prognosis. (4) Cancer-related basic research and clinical transformation research based on big data and artificial intelligence. (5) Accurate detection and diagnosis of early cancer, intelligent prediction models of neoadjuvant treatment, and targeted treatment response of cancer.
Transcriptional Regulation In Metabolism And Immunology
DOWNLOAD
Author : Chunjie Jiang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-03
Transcriptional Regulation In Metabolism And Immunology written by Chunjie Jiang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-03 with Science categories.
Novel Diagnostic And Therapeutic Strategies In The Management Of Cerebral Gliomas
DOWNLOAD
Author : Valeria Barresi
language : en
Publisher: Frontiers Media SA
Release Date : 2024-10-29
Novel Diagnostic And Therapeutic Strategies In The Management Of Cerebral Gliomas written by Valeria Barresi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-29 with Medical categories.
Cerebral gliomas account for 45% of all primary central nervous system (CNS) tumors. The median survival after the initial diagnosis of glioblastoma (GBM) is only 15 months, and less than 10% of patients survive three years post-diagnosis. Surgical treatment followed by adjuvant therapies such as radiotherapy and chemotherapy represents the classical strategy in glioma management. The revised WHO 2016 classification now distinguishes the oligodendrogliomas with 1p19q codeletion and IDH mutation from the astrocytomas with or without IDH mutations, thereby creating homogenous and pathologically distinct subgroups. While the status of gene expression and mutations define components of GBM subtypes, it was also found that response to therapies was different for each subtype, suggesting that personalized treatment based on genomic alterations could lead to a more favorable outcome for this disease.
Research Anthology From Life Science And Biotechnology
DOWNLOAD
Author : Dr Ramya R
language : en
Publisher: Self
Release Date : 2024-09-24
Research Anthology From Life Science And Biotechnology written by Dr Ramya R and has been published by Self this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-24 with Science categories.
From the intricate world of ocular biomarkers to the potential of stem cell therapy in regenerating damaged tissues, this book provides valuable insights into a multitude of biomedical fields. The inclusion of topics such as spatial transcriptomics, gene circuits, and nanotechnology highlights the interdisciplinary nature of modern scientific inquiry and the promise it holds for developing innovative solutions to pressing global health challenges. This is edited book project entitled “Research Anthology from Life science and Biotechnology” is a record of students work under my guidance. Research Anthology from Life Science and Biotechnology 978-93-341-2260-2 Dr Ramya Raghavan https://orcid.org/0000-0002-9953-543X Sri Sathya Sai University for Human Excellence, India DOI: 10.5281/zenodo.13824272
Ferroptosis In Cancer And Beyond Volume Ii
DOWNLOAD
Author : Yanqing Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-29
Ferroptosis In Cancer And Beyond Volume Ii written by Yanqing Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-29 with Medical categories.
Immunoinformatics In The Age Of Ai Machine Learning Methods For Immune System Modeling
DOWNLOAD
Author : Dr. Calvin Ronchen Wei
language : en
Publisher: Xoffencer International Book Publication house
Release Date : 2024-11-28
Immunoinformatics In The Age Of Ai Machine Learning Methods For Immune System Modeling written by Dr. Calvin Ronchen Wei and has been published by Xoffencer International Book Publication house this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-28 with Computers categories.
Immunoinformatics, an interdisciplinary field at the nexus of immunology, bioinformatics, and computational science, has been profoundly transformed by the advent of artificial intelligence (AI) and machine learning (ML) technologies. As the immune system is an intricate and dynamic network responsible for protecting organisms from pathogens, its study presents vast complexities requiring sophisticated computational tools. The integration of ML has enabled significant strides in understanding immune responses, predicting immune epitopes, designing vaccines, and modeling interactions between pathogens and the host immune system. ML algorithms, particularly those utilizing deep learning frameworks, have shown remarkable capabilities in analyzing vast genomic, proteomic, and transcriptomic datasets, revealing patterns and insights that were previously beyond human reach. These advancements are particularly crucial in the current era, where rapid responses to emerging diseases and pandemics necessitate unprecedented speed and precision in immune system research. AI-powered tools have revolutionized vaccine development by predicting antigenic determinants with high accuracy, thereby reducing reliance on traditional trial-and-error methods. This approach has accelerated the development of mRNA vaccines, which played a critical role during the COVID-19 pandemic. Furthermore, ML techniques like support vector machines, neural networks, and ensemble learning have been employed to simulate immune system dynamics, enabling researchers to forecast immune responses to various interventions. These models are instrumental in identifying biomarkers for autoimmune diseases, allergies, and cancer immunotherapy, paving the way for personalized medicine. Moreover, the incorporation of natural language processing in immunoinformatics has facilitated the curation and synthesis of vast biomedical literature, providing researchers with actionable insights into immune-related mechanisms and therapies. However, the application of ML in immunoinformatics is not without challenges. Issues such as data heterogeneity, interpretability of ML models, and the need for high-quality annotated datasets remain significant barriers. Ethical considerations, including data privacy and the equitable distribution of AI-enabled solutions, are also critical concerns. Addressing these challenges requires collaborative efforts between immunologists, data scientists, and ethicists, ensuring that advancements in AI are harnessed responsibly and inclusively
Immune Cell Lineage Reprogramming In Cancer
DOWNLOAD
Author : Jianmei Wu Leavenworth
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-22
Immune Cell Lineage Reprogramming In Cancer written by Jianmei Wu Leavenworth and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-22 with Medical categories.
Topic Editor Dr. Lewis Shi received financial support from Varian Medical System, Inc. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Advances In Human Immune System His Mouse Models For Studying Human Hematopoiesis And Cancer Immunotherapy
DOWNLOAD
Author : Yasuyuki Saito
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-10
Advances In Human Immune System His Mouse Models For Studying Human Hematopoiesis And Cancer Immunotherapy written by Yasuyuki Saito and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-10 with Medical categories.
Topic Editor Prof. Aimin Xu receives financial support from Servier Laboratories. The other Topic Editors declare no competing interests with regards to the Research Topic theme.
Immune Related Non Communicable Diseases In Africa
DOWNLOAD
Author : Mohamed-Ridha Barbouche
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-17
Immune Related Non Communicable Diseases In Africa written by Mohamed-Ridha Barbouche and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-17 with Medical categories.