Using Mathematics To Understand Biological Complexity
DOWNLOAD
Download Using Mathematics To Understand Biological Complexity PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Using Mathematics To Understand Biological Complexity book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Using Mathematics To Understand Biological Complexity
DOWNLOAD
Author : Rebecca Segal
language : en
Publisher: Springer Nature
Release Date : 2020-12-29
Using Mathematics To Understand Biological Complexity written by Rebecca Segal and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-29 with Mathematics categories.
This volume tackles a variety of biological and medical questions using mathematical models to understand complex system dynamics. Working in collaborative teams of six, each with a senior research mentor, researchers developed new mathematical models to address questions in a range of application areas. Topics include retinal degeneration, biopolymer dynamics, the topological structure of DNA, ensemble analysis, multidrug-resistant organisms, tumor growth modeling, and geospatial modeling of malaria. The work is the result of newly formed collaborative groups begun during the Collaborative Workshop for Women in Mathematical Biology hosted by the Institute of Pure and Applied Mathematics at UCLA in June 2019. Previous workshops in this series have occurred at IMA, NIMBioS, and MBI.
The Mathematics And Mechanics Of Biological Growth
DOWNLOAD
Author : Alain Goriely
language : en
Publisher: Springer
Release Date : 2017-05-29
The Mathematics And Mechanics Of Biological Growth written by Alain Goriely and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-29 with Mathematics categories.
This monograph presents a general mathematical theory for biological growth. It provides both a conceptual and a technical foundation for the understanding and analysis of problems arising in biology and physiology. The theory and methods are illustrated on a wide range of examples and applications. A process of extreme complexity, growth plays a fundamental role in many biological processes and is considered to be the hallmark of life itself. Its description has been one of the fundamental problems of life sciences, but until recently, it has not attracted much attention from mathematicians, physicists, and engineers. The author herein presents the first major technical monograph on the problem of growth since D’Arcy Wentworth Thompson’s 1917 book On Growth and Form. The emphasis of the book is on the proper mathematical formulation of growth kinematics and mechanics. Accordingly, the discussion proceeds in order of complexity and the book is divided into five parts. First, a general introduction on the problem of growth from a historical perspective is given. Then, basic concepts are introduced within the context of growth in filamentary structures. These ideas are then generalized to surfaces and membranes and eventually to the general case of volumetric growth. The book concludes with a discussion of open problems and outstanding challenges. Thoughtfully written and richly illustrated to be accessible to readers of varying interests and background, the text will appeal to life scientists, biophysicists, biomedical engineers, and applied mathematicians alike.
Understanding Complex Biological Systems With Mathematics
DOWNLOAD
Author : Ami Radunskaya
language : en
Publisher: Springer
Release Date : 2018-10-24
Understanding Complex Biological Systems With Mathematics written by Ami Radunskaya and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-24 with Mathematics categories.
This volume examines a variety of biological and medical problems using mathematical models to understand complex system dynamics. Featured topics include autism spectrum disorder, ectoparasites and allogrooming, argasid ticks dynamics, super-fast nematocyst firing, cancer-immune population dynamics, and the spread of disease through populations. Applications are investigated with mathematical models using a variety of techniques in ordinary and partial differential equations, difference equations, Markov-chain models, Monte-Carlo simulations, network theory, image analysis, and immersed boundary method. Each article offers a thorough explanation of the methodologies used and numerous tables and color illustrations to explain key results. This volume is suitable for graduate students and researchers interested in current applications of mathematical models in the biosciences. The research featured in this volume began among newly-formed collaborative groups at the 2017 Women Advancing Mathematical Biology Workshop that took place at the Mathematical Biosciences Institute in Columbus, Ohio. The groups spent one intensive week working at MBI and continued their collaborations after the workshop, resulting in the work presented in this volume.
Mathematical Concepts And Methods In Modern Biology
DOWNLOAD
Author : Raina Robeva
language : en
Publisher: Academic Press
Release Date : 2013-02-26
Mathematical Concepts And Methods In Modern Biology written by Raina Robeva and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-26 with Mathematics categories.
Mathematical Concepts and Methods in Modern Biology offers a quantitative framework for analyzing, predicting, and modulating the behavior of complex biological systems. The book presents important mathematical concepts, methods and tools in the context of essential questions raised in modern biology.Designed around the principles of project-based learning and problem-solving, the book considers biological topics such as neuronal networks, plant population growth, metabolic pathways, and phylogenetic tree reconstruction. The mathematical modeling tools brought to bear on these topics include Boolean and ordinary differential equations, projection matrices, agent-based modeling and several algebraic approaches. Heavy computation in some of the examples is eased by the use of freely available open-source software. - Features self-contained chapters with real biological research examples using freely available computational tools - Spans several mathematical techniques at basic to advanced levels - Offers broad perspective on the uses of algebraic geometry/polynomial algebra in molecular systems biology
Modeling Life
DOWNLOAD
Author : Alan Garfinkel
language : en
Publisher: Springer
Release Date : 2017-09-06
Modeling Life written by Alan Garfinkel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-06 with Mathematics categories.
This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?
Mathematical Modeling In Systems Biology
DOWNLOAD
Author : Brian P. Ingalls
language : en
Publisher: MIT Press
Release Date : 2022-06-07
Mathematical Modeling In Systems Biology written by Brian P. Ingalls and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-07 with Science categories.
An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.
Exploring Mathematical Modeling In Biology Through Case Studies And Experimental Activities
DOWNLOAD
Author : Rebecca Sanft
language : en
Publisher: Academic Press
Release Date : 2020-04-01
Exploring Mathematical Modeling In Biology Through Case Studies And Experimental Activities written by Rebecca Sanft and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-01 with Science categories.
Exploring Mathematical Modeling in Biology through Case Studies and Experimental Activities provides supporting materials for courses taken by students majoring in mathematics, computer science or in the life sciences. The book's cases and lab exercises focus on hypothesis testing and model development in the context of real data. The supporting mathematical, coding and biological background permit readers to explore a problem, understand assumptions, and the meaning of their results. The experiential components provide hands-on learning both in the lab and on the computer. As a beginning text in modeling, readers will learn to value the approach and apply competencies in other settings. Included case studies focus on building a model to solve a particular biological problem from concept and translation into a mathematical form, to validating the parameters, testing the quality of the model and finally interpreting the outcome in biological terms. The book also shows how particular mathematical approaches are adapted to a variety of problems at multiple biological scales. Finally, the labs bring the biological problems and the practical issues of collecting data to actually test the model and/or adapting the mathematics to the data that can be collected.
Mathematical Models In Biology
DOWNLOAD
Author : Leah Edelstein-Keshet
language : en
Publisher: SIAM
Release Date : 1988-01-01
Mathematical Models In Biology written by Leah Edelstein-Keshet and has been published by SIAM this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-01-01 with Mathematics categories.
Mathematical Models in Biology is an introductory book for readers interested in biological applications of mathematics and modeling in biology. A favorite in the mathematical biology community, it shows how relatively simple mathematics can be applied to a variety of models to draw interesting conclusions. Connections are made between diverse biological examples linked by common mathematical themes. A variety of discrete and continuous ordinary and partial differential equation models are explored. Although great advances have taken place in many of the topics covered, the simple lessons contained in this book are still important and informative. Audience: the book does not assume too much background knowledge--essentially some calculus and high-school algebra. It was originally written with third- and fourth-year undergraduate mathematical-biology majors in mind; however, it was picked up by beginning graduate students as well as researchers in math (and some in biology) who wanted to learn about this field.
Mathematics And The Natural Sciences
DOWNLOAD
Author : Francis Bailly
language : en
Publisher: World Scientific
Release Date : 2011
Mathematics And The Natural Sciences written by Francis Bailly and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.
The book aims at the identification of the organising concepts of some physical and biological phenomena, by means of an analysis of the foundations of mathematics and of physics. This is done in the perspective of unifying phenomena, of bringing different conceptual universes into dialog. The analysis of the role of “order” and of symmetries in the foundations of mathematics is linked to the main invariants and principles, among which the geodesic principle (a consequence of symmetries), which govern and confer unity to the various physical theories. Moreover, we attempt to understand causal structures, a central element of physical intelligibility, in terms of symmetries and their breakings. The importance of the mathematical tool is also highlighted, enabling us to grasp the differences in the models for physics and biology which are proposed by continuous and discrete mathematics, such as computational simulations. A distinction between principles of (conceptual) construction and principles of proofs, both in physics and in mathematics, guides this part of the work.As for biology, being particularly difficult and not as thoroughly examined at a theoretical level, we propose a “unification by concepts”, an attempt which should always precede mathematisation. This constitutes an outline for unification also basing itself upon the highlighting of conceptual differences, of complex points of passage, of technical irreducibilities of one field to another. Indeed, a monist point of view such as ours should not make us blind: we, the living objects, are surely just big bags of molecules or, at least, this is our main metaphysical assumption. The point though is: which theory can help us to better understand these bags of molecules, as they are, indeed, rather “singular”, from the physical point of view. Technically, this singularity is expressed by the notion of “extended criticality”, a notion that logically extends the pointwise critical transitions in physics.
Easy Mathematics For Biologists
DOWNLOAD
Author : Peter C. Foster
language : en
Publisher: CRC Press
Release Date : 2003-09-02
Easy Mathematics For Biologists written by Peter C. Foster and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Mathematics categories.
Because elementary mathematics is vital to be able to properly design biological experiments and interpret their results. As a student of the life sciences you will only make your life harder by ignoring mathematics entirely. Equally, you do not want to spend your time struggling with complex mathematics that you will never use. This book is the perfect answer to your problems. Inside, it explains the necessary mathematics in easy-to-follow steps, introducing the basics and showing you how to apply these to biological situations. Easy Mathematics for Biologists covers the basic mathematical ideas of fractions, decimals and percentages, through ratio and proportion, exponents and logarithms, to straight line graphs, graphs that are not straight lines, and their transformation. Direct application of each of these leads to a clear understanding of biological calculations such as those involving concentrations and dilutions, changing units, pH, and linear and non-linear rates of reaction. Each chapter contains worked examples, and is followed by numerous problems, both pure and applied, that can be worked through in your own time. Answers to these can be found at the back.