Vasoplegic Endothelial Dysfunction


Vasoplegic Endothelial Dysfunction
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Vasoplegic Endothelial Dysfunction


Vasoplegic Endothelial Dysfunction
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Author : Paulo Roberto Barbosa Evora
language : en
Publisher: Springer Nature
Release Date : 2021-05-31

Vasoplegic Endothelial Dysfunction written by Paulo Roberto Barbosa Evora and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-31 with Medical categories.


This unique work presents one of the most significant organ failure condition – cardiocirculatory shock – and the prominent role of Methylene Blue (MB). Through their extensive experience, the authors’ consider that the lifesaving feature of MB is still underestimated. For this reason they outline key concepts of MB, mentioning essential experimental data, yet focusing mainly on its application in the care of critically ill patients. In an easy-to-read format, the 18 chapters were organized in a didactically structured order, distributed in four parts. The first part introduces the general conceptual aspects and physiology of the endothelium. The second part presents the particularities of endothelial dysfunction in different types of shock. Methylene blue is discussed in detail in the third part. In the fourth part, particular situations of endothelial dysfunction, such as heart surgery and organ transplantation, are described. Additionally, the two complementary subjects of acid-base balance and the therapeutic use of inhaled nitric oxide are mentioned. Finally, looking for therapeutic alternatives for what we classify as "vasoplegic endothelial dysfunction", MB remains promising as an adjuvant to sympathomimetic amines. The combination of three recently proposed concepts may be useful in obtaining better results against the high mortality rates in critically ill patients. These three concepts are "wide-spectrum vasopressors", vasopressor economy strategies, and microcirculation protection against the harmful effects of using high concentrations of amines. This book ́s translational approach will appeal to a variety of readers within the health specialties of medicine, biomedicine, physiotherapy, nursing, odontology, and basic science.



Endothelium And Cardiovascular Diseases


Endothelium And Cardiovascular Diseases
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Author : Protasio Lemos Da Luz
language : en
Publisher: Academic Press
Release Date : 2018-02-03

Endothelium And Cardiovascular Diseases written by Protasio Lemos Da Luz and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-03 with Medical categories.


Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians. Provides a complete overview of endothelial function in health and diseases, along with an assessment of new information Includes coverage of groundbreaking areas, including the artificial LDL particle, the development of a new anti-erectile dysfunction agent, a vaccine for atherosclerosis, coronary calcification associated with red wine, and the interplay of endoplasmic reticulum/oxidative stress Explores the genetic features of endothelium and the interaction between basic knowledge and clinical syndromes



Urinary Antiinfectives Advances In Research And Application 2012 Edition


Urinary Antiinfectives Advances In Research And Application 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26

Urinary Antiinfectives Advances In Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Medical categories.


Urinary Antiinfectives—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Urinary Antiinfectives. The editors have built Urinary Antiinfectives—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Urinary Antiinfectives in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Urinary Antiinfectives—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.



Cardiac Surgery


Cardiac Surgery
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Author : Miguel Maluf
language : en
Publisher: BoD – Books on Demand
Release Date : 2014-02-26

Cardiac Surgery written by Miguel Maluf and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-26 with Medical categories.


In this book it is shown how this specialty has evolved over the past 20 years, with significant advances in diagnosis and palliative and definitive techniques for correction of cardiovascular diseases. The book contains 10 cahpters, which are showing the classical adult and pediatric cardiac surgery.



Principles And Practice Of Critical Care


Principles And Practice Of Critical Care
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Author : P. K. Verma
language : en
Publisher: Wolters kluwer india Pvt Ltd
Release Date : 2019-09-08

Principles And Practice Of Critical Care written by P. K. Verma and has been published by Wolters kluwer india Pvt Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-08 with Medical categories.


This edition is presented in a totally new and reader-friendly format. The focus of this volume is on holistic management of critically ill adult patients and it builds upon concepts one step at a time – allowing one the opportunity to develop competence at one's own pace.



Oxford Textbook Of Anaesthesia For The Obese Patient


Oxford Textbook Of Anaesthesia For The Obese Patient
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Author : Ashish Sinha
language : en
Publisher: Oxford University Press
Release Date : 2021

Oxford Textbook Of Anaesthesia For The Obese Patient written by Ashish Sinha and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Medical categories.


Obesity is a global public health issue; significant numbers of the world's population are overweight, growing numbers are obese, and many are morbidly obese. As obesity is associated with a range of co-morbidities (namely cardiovascular disease, diabetes, cancer, depression, and sleep apnoea), it presents a daunting peri-operative challenge to the anaesthetist. The increasing size and weight of patients presenting for surgery involves multiple issues from starting intravenous lines through to intubation and ventilation challenges. The Oxford Textbook of Anaesthesia for the Obese Patient is a highly authoritative, evidence-based account of the principles and clinical practice within the field. Across 36 chapters, this resource provides comprehensive coverage of all aspects of the subject including physiological and pharmacological modifications in the obese patient, bariatric and non-bariatric surgery, specific clinical issues such as fluid management and tissue oxygenation, as well as challenges arising from obesity in the setting of paediatrics, obstetrics, intensive care and trauma. Written and edited by experts in the field, this resource is the definitive guide to clinical management of the obese patient, exploring various international approaches to practice, with helpful case studies, and practical advice on common intra-operative challenges, and how to resolve them using evidence and best practice.



Irwin And Rippe S Intensive Care Medicine


Irwin And Rippe S Intensive Care Medicine
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Author : Craig M. Lilly
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2023-05-25

Irwin And Rippe S Intensive Care Medicine written by Craig M. Lilly and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-25 with Medical categories.


Covering both the theoretical and practical aspects of critical care,Irwin & Rippe’s Intensive Care Medicine, Ninth Edition, provides state-of-the-art, evidence-based knowledge for specialty physicians and non-physicians practicing in the adult intensive care environment. Drs. Craig M. Lilly, Walter A. Boyle, and Richard S. Irwin, along with a team of expert contributing authors and education expert, William F. Kelly, offer authoritative, comprehensive guidance from an interprofessional, collaborative, educational, and scholarly perspective, encompassing all adult critical care specialties.



Coagulation Endothelial Dysfunction An Issue Of Critical Care Clinics


Coagulation Endothelial Dysfunction An Issue Of Critical Care Clinics
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Author : Hernando Gomez
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-03-19

Coagulation Endothelial Dysfunction An Issue Of Critical Care Clinics written by Hernando Gomez and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-19 with Medical categories.


This issue of Critical Care Clinics, guest edited by Drs. Hernando Gomez Danies and Joseph Carcillo, focuses on Coagulation/Endothelial Dysfunction. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: Cell-cell communication breakdown and endothelial dysfunction; Role of the Tie2/Angiopoetin pathway in endothelial dysfunction; The Glycocalyx; Platelet activation and endothelial dysfunction; Role of antithrombin III and tissue factor pathway; Red blood cell dysfunction; Microvascular hemodynamics, autoregulation and mechanotransduction control of blood flow distribution; Nitric oxide and endothelial dysfunction; Microvascular dysfunction; Hemolytic Uremic Syndrome and atypical HUS; Thrombotic thrombocytopenic purpura, Heparin induced thrombocytopenia and Disseminated intravascular coagulation in the critically ill; Thrombocytopenia associated multiple organ failure (TAMOF); Meningococcemia; Immune consequences of endothelial dysfunction during sepsis; Therapeutic targets in thrombotic microangiopathies with a focus on endothelial disorders; and Coagulation disorders in HLH/Macrophage activation syndrome.



Multiple Organ Failure


Multiple Organ Failure
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Author : Arthur E. Baue
language : en
Publisher: Springer Science & Business Media
Release Date : 2000-06-08

Multiple Organ Failure written by Arthur E. Baue and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-06-08 with Medical categories.


Inflammation in itself is not to be considered as a disease . . . and in disease, where it can alter the diseased mode of action, it likewise leads to a cure; but where it cannot accomplish that solitary purpose . . . it does mischief - John Hunter, A Treatise on the Blood, ITfIlammation, and Gunshot Woundr (London, 1794)1 As we reached the millennium, we recognized the gap between our scientific knowledge of biologic processes and our more limited clinical capabilities in the care of patients. Our science is strong. Molecular biology is powerful, but our therapy to help patients is weaker and more limited. For this reason, this book focuses on the problems of multiple organ failure (MOF), multiple organ dysfunction syndrome (MODS), and systemic inflammatory response syndrome is, patients who have severe injuries; require major, (SIRS) in high-risk patients, that overwhelming operations; or have serious illnesses requiring intensive care; patients who have diseases elsewhere, in other organs or systems, that limit their capabilities to survive a new insult; and patients who are elderly or at high risk for sepsis or other complications. These are the patients who need our help. They need the advances in science, in molecular biology, immunology, pathophysiology, biochemistry, genetics, high technology, and other areas of maximum support at the bedside. These advances could potentially have the greatest impact on improving patient care.



Evidence Based Critical Care


Evidence Based Critical Care
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Author : Paul Ellis Marik
language : en
Publisher: Springer
Release Date : 2014-12-08

Evidence Based Critical Care written by Paul Ellis Marik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-08 with Medical categories.


This is the premier evidence-based textbook in critical care medicine. The Third Edition features updated and revised chapters, numerous new references, streamlined content, and new chapters on key topics such as the new paradigm in critical care medicine, cardiac output monitoring, surgical optimization, vital signs, and arterial blood gas analysis. The book maintains the author’s trademark humor and engaging writing style and is suitable for a broad and diverse audience of medical students, residents, fellows, physicians, nurses, and respiratory therapists who seek the latest and best evidence in critical care. From reviews of previous editions: “This is an excellent introduction to the concept of evidence-based medicine...The writing is clear, logical, and highly organized, which makes for fast and enjoyable reading. I believe this book will get daily use in most intensive care units, by a wide range of readers.” –Respiratory Care “This is one of the most comprehensive handbooks on critical care medicine with a strong emphasis on evidence base...Overall, this book should be useful for junior doctors or intensive care trainees who are starting their term in an intensive care unit.” –Anaesthesia and Intensive Care