Vdac Structure And Function An Up To Date View
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Vdac Structure And Function An Up To Date View
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Author : Vito De Pinto
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-03
Vdac Structure And Function An Up To Date View written by Vito De Pinto and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-03 with Science categories.
Membrane Protein Complexes Structure And Function
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Author : J. Robin Harris
language : en
Publisher: Springer
Release Date : 2018-02-20
Membrane Protein Complexes Structure And Function written by J. Robin Harris and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-20 with Science categories.
This edited book contains a compilation of 14 advanced academic chapters dealing with the structure and function of membrane protein complexes. This rapidly advancing important field of study closely parallels those on soluble protein complexes, and viral protein and nucleoprotein complexes. Diverse topics are included in this book, ranging from membrane–bound enzymes to ion channels, proton pumps and photosystems. Data from X-ray crystallography, cryo-electron microscopy and other biophysical and biochemical techniques are presented throughout the book. There is extensive use of colour figures of protein structures. Throughout the book structure and function are closely correlated. The two editors, Egbert Boekema and J. Robin Harris, have worked on aspects of membrane and soluble proteins throughout their scientific careers and also have much publishing experience. The Subcellular Biochemistry series has expanded considerably in recent years, including several related volumes. The theme of protein complexes will be continued within several future volumes, thereby creating encyclopaedic coverage. The chapter topics within this book are particularly relevant to those involved in the biological and biomedical sciences. It is aimed at the advanced undergraduates, postgraduates and established researchers within this broad field. It is hoped that the book will be of interest and use to those involved with the study of cellular membranes and their associated proteins.
Hidden Secrets And Lessons From The Crystal Structures Of Integral Membrane Proteins Channels Pumps And Receptors
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Author : Mario Díaz
language : en
Publisher: Frontiers Media SA
Release Date : 2019-03-07
Hidden Secrets And Lessons From The Crystal Structures Of Integral Membrane Proteins Channels Pumps And Receptors written by Mario Díaz and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-07 with categories.
Molecular System Bioenergetics
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Author : Valdur Saks
language : en
Publisher: John Wiley & Sons
Release Date : 2008-01-08
Molecular System Bioenergetics written by Valdur Saks and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-08 with Science categories.
In this first integrated view, practically each of the world's leading experts has contributed to this one and only authoritative resource on the topic. Bringing systems biology to cellular energetics, they address in detail such novel concepts as metabolite channeling and medical aspects of metabolic syndrome and cancer.
Molecular Biology Of Mitochondrial Transport Systems
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Author : Michael Forte
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Molecular Biology Of Mitochondrial Transport Systems written by Michael Forte and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
Mitochondrial transport systems are essential to mitochondrial function and therefore to energy homeostasis within the cell. The book contains studies utilizing the techniques of biochemistry, physiology, molecular biology and genetics to reveal the structure and function of mitochondrial transport systems. It is divided into the following six sections: - Proton Translocation: The Uncoupling Protein and the ATPase; - Carriers and Transporters; - Mitochondrial Ion Channels; Structure of the Outer Mitochondrial Membrane Channel, VDAC; - VDAC, Peripheral Kinases and Energy Utilization; - Mitochondrial Channels in Humans and Relationship to Disease.
Molecular Aspects Of The Stress Response Chaperones Membranes And Networks
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Author : Peter Csermely
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-09
Molecular Aspects Of The Stress Response Chaperones Membranes And Networks written by Peter Csermely and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-09 with Science categories.
This book makes a novel synthesis of the molecular aspects of the stress response and long term adaptation processes with the system biology approach of biological networks. Authored by an exciting mixture of top experts and young rising stars, it provides a comprehensive summary of the field and identifies future trends.
Mitochondria And Their Role In Cardiovascular Disease
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Author : José Marín-García
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-19
Mitochondria And Their Role In Cardiovascular Disease written by José Marín-García and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-19 with Medical categories.
Over the past two decades, due to dramatic advances in molecular and cell biology, biochemistry, and genetics, our view on mitochondria as a relatively static cellular powerhouse has changed radically. We now know that these organelles play a critical role in the normal and in the damaged heart. Written by Dr. José Marín-García, Director of the Molecular Cardiology and Neuromuscular Institute, Mitochondria and Their Role in Cardiovascular Disease brings readers up- to-date on the many significant advances in the field of mitochondrial cardiovascular medicine. The book begins with a general introduction to mitochondria, followed by laboratory methods to study the structure and function of the organelle, regulation of replication and biogenesis, and the mechanisms and functional consequences of mitophagia and mitochondrial dynamics. Subsequent chapters deal with mitochondrial oxidative stress and the role that the organelle plays in cell signaling and cell death. Discussions will be undertaken on the biochemistry of mitochondrial cell signaling, including the nature of the proteins engaged in these processes, many of them only recently discovered. Later chapters examine the role of mitochondria and mitochondrial abnormalities in cardiovascular diseases, including their diagnosis, therapeutic options currently available, animal models of mitochondrial disease, and new frontiers in mitochondria cardiovascular medicine, including areas of research that are relatively new or developing, such as proteomics, next generation sequencing, and systems biology.
Chloride Channels
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Author :
language : en
Publisher: Academic Press
Release Date : 1994-09-15
Chloride Channels written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-09-15 with Science categories.
The amount of new information on the molecular biology of chloride channels has grown tremendously in recent years. This large amount of information gives some unique and, in some instances, surprising insights into the function and structure of chloride channels which are present in every cell. This volume contains a series of in-depth reviews of chloride channel physiology, biophysics, and molecular biology. The reviews cover chloride channels found in the plasma membrane as well as in organelles of both plant and animal cells. Key Features * Discusses CFTR, the cystic fibrosis transmembrane regulator, which is responsible for CF and the CIC-family of chloride channels responsible for myotonia congenita * In-depth reviews of chloride channel physiology, biophysics, and molecular biology * Reviews chloride channels found in the plasma membrane and in organelles of both plant and animal cells
Bacterial And Eukaryotic Porins
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Author : Roland Benz
language : en
Publisher: Wiley-VCH Verlag GmbH
Release Date : 2004
Bacterial And Eukaryotic Porins written by Roland Benz and has been published by Wiley-VCH Verlag GmbH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Eukaryotic Cells categories.
For the first time, current knowledge on this important of proteins is now available in a single resource. This first book on porins in prokaryotes and eukaryotes relates the known physiological functions of porins to their molecular structure and mechanism. It brings together biophysical evidence with studies performed in a cellular context, presenting a unified picture of the fundamental importance of porins for cellular function. From the contents: Structure of Prokaryotic Porins Functional Reconstitution of Porins Regulation of Bacterial Porin Function Role of Porins in Antibiotic Susceptibility Drug Efflux and Protein Export through Porins Structure and Function of Mitochondrial Porins VDAC Function in Intracellular Signalling and Apoptosis With 16 contributions by an interdisciplinary team of leading porin researchers, this reference is essential reading for every molecular or structural biologist with an interest in this important protein family.
Structural Biology In Drug Discovery
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Author : Jean-Paul Renaud
language : en
Publisher: John Wiley & Sons
Release Date : 2020-01-09
Structural Biology In Drug Discovery written by Jean-Paul Renaud and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-09 with Medical categories.
With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins