Vegf And Cancer
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Vegf And Cancer
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Author : Judith H. Harmey
language : en
Publisher: Springer Science & Business Media
Release Date : 2004
Vegf And Cancer written by Judith H. Harmey and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.
VEGF and Canceris a comprehensive and up to date review of current knowledge on the role of vascular endothelial growth factor (VEGF) in cancer. Key Features: -Discussion of VEGF as potent angiogenic factor and its role in tumor angiogenesis, -Review of the biology, molecular properties and regulation of VEGF, -Discussion of the role of VEGF in a range of different tumor types, both solid tumors and haematological cancers, -Review of the therapeutic potential of different approaches to block VEGF, -Review of recent evidence that in addition to its role as an endothelial cell mitogen, VEGF may also be an autocrine growth factor for tumor cells, regulating survival and invasion. This book is aimed at scientists new to angiogenesis and VEGF biology and provides new information for established researchers and scientists. It will also be a useful text for clinicians interested in anti-angiogenic therapy for treatment of human cancers.
Vegf And Cancer
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Author :
language : en
Publisher:
Release Date : 2004
Vegf And Cancer written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cancer categories.
VEGF and Cancer is a comprehensive and up to date review of current knowledge on the role of vascular endothelial growth factor (VEGF) in cancer. Key Features: This book is aimed at scientists new to angiogenesis and VEGF biology and provides new information for established researchers and scientists.
Physiologic And Pathologic Angiogenesis
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Author : Dan Simionescu
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-04-05
Physiologic And Pathologic Angiogenesis written by Dan Simionescu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-05 with Medical categories.
The purpose of this book is to highlight novel advances in the field and to incentivize scientists from a variety of fields to pursue angiogenesis as a research avenue. Blood vessel formation and maturation to capillaries, arteries, or veins is a fascinating area which can appeal to multiple scientists, students, and professors alike. Angiogenesis is relevant to medicine, engineering, pharmacology, and pathology and to the many patients suffering from blood vessel diseases and cancer, among others. We are hoping that this book will become a source of inspiration and novel ideas for all.
Molecular Mechanisms Of Angiogenesis
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Author : Jean-Jacques Feige
language : en
Publisher: Springer
Release Date : 2014-05-27
Molecular Mechanisms Of Angiogenesis written by Jean-Jacques Feige and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-27 with Science categories.
Angiogenesis is a multi-stage process that drives the generation of new blood and lymphatic vessels from pre-existing ones. It is highly active during embryogenesis, largely inactive during adulthood but reactivated during wound healing and under a number of pathological conditions including cancer and ocular diseases. In addition to endothelial cells, which line the walls of the vessels, several other cell types (pericytes, macrophages, progenitor cells...) also contribute to angiogenesis. A number of signaling pathways are activated and very finely tune the delicate morphogenetic events that ultimately lead to the formation of stable blood proof neovessels. This book reviews recent advances in our understanding of the molecular and cellular mechanisms of angiogenesis, with a focus on how to integrate these observations into the context of developmental, post-natal and pathological neovascularization. The book was published under the auspices of the French Angiogenesis Society. Most contributors are prominent members of this Society or international researchers who have actively contributed to the Annual Meetings of the Society.
History Of Research On Tumor Angiogenesis
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Author : Domenico Ribatti
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-16
History Of Research On Tumor Angiogenesis written by Domenico Ribatti and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-16 with Medical categories.
In 1971, J. Folkman published in the “New England Journal of Medicine” a hypothesis that tumor growth is angiogenesis-dependent. Folkman introduced the concept that tumors probably secrete diffusible molecules that could stimulate the growth of new blood vessels toward the tumor and that the resulting tumor neovascularization could conceivably be prevented or interrupted by angiogenesis inhibitors. Solid and haematological tumors consist of an avascular and a subsequent vascular phase. Assuming that this depends on the release of angiogenic factors, acquisition of angiogenic capability can be seen as an expression of progression from neoplastic transformation to tumor growth and metastasis. Beginning in the 1980’s, the biopharmaceutical industry began exploiting the field of antiangiogenesis for creating new therapeutic compounds for modulating new blood vessels in tumor growth. In 2004, Avastin (Bevacizumab), a humanized anti-VEGF monoclonal antibody, was the first angiogenesis inhibitor approved by the Food and Drug Administration for the treatment of colorectal cancer. At present, it has been estimated that over 20,000 cancer patients worldwide have received experimental form of antiangiogenic therapy. This book offers a historical account of the relevant literature. It also emphasizes the crucial and paradigmatic role of angiogenesis as a biological process and the significance of antiangiogenic approach for the treatment of tumors.
Vascular Endothelial Growth Factor Vegf
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Author : Marcellus L. Parker
language : en
Publisher: Nova Science Publishers
Release Date : 2013
Vascular Endothelial Growth Factor Vegf written by Marcellus L. Parker and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Growth factors categories.
Vascular endothelial growth factor (VEGF) is one of the most potent and specific angiogenic factors. The physiologic roles of VEGF in humans include neovascularisation and endometrium implantation, and in pathological processes VEGF has been involved in the initiation, growth, and metastasis of tumors. In this book, the authors discuss the biology, regulation and clinical significance of VEGF. Topics include VEGF signalling and multi-drug resistance transporter (ABCB1); clinical imaging of tumour vascularity as a biomarker during anti-VEGF therapy; VEGF and kidney cancer; the effect of VEGF on oocyte maturation and embryo development of bovine and ovine in vitro and its mechanisms; physiological functions of VEGF in the retina; VEGF in the regulation of gingival venule diameter under physiological and pathological circumstances; regulation of VEGF expression by progesterone and estradiol in normal and cancer cells; ethanol stimulated angiogenesis via VEGF and protection from ischemia and reperfusion injury; and the role of VEGF in major depression.
Vegf Vegfr Inhibitors Advances In Research And Application 2013 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2013-06-21
Vegf Vegfr Inhibitors Advances In Research And Application 2013 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-21 with Medical categories.
VEGF - VEGFR Inhibitors—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Sorafenib in a concise format. The editors have built VEGF - VEGFR Inhibitors—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Sorafenib in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of VEGF - VEGFR Inhibitors—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Antiangiogenic Cancer Therapy
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Author : Darren W. Davis
language : en
Publisher: CRC Press
Release Date : 2007-07-25
Antiangiogenic Cancer Therapy written by Darren W. Davis and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-25 with Medical categories.
Top Investigators Explore the Complexities of Angiogenesis Cancer Research The targeting of tumor angiogenesis has evolved into one of the most widely pursued therapeutic strategies. However, as of yet, no antiangiogenic agent used as a monotherapy has demonstrated a survival benefit in a randomized Phase III trial. The combination of bev
Vascular Endothelial Growth Factor Vegf
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Author : Marcellus L. Parker
language : en
Publisher:
Release Date : 2013
Vascular Endothelial Growth Factor Vegf written by Marcellus L. Parker and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.
Vascular endothelial growth factor (VEGF) is one of the most potent and specific angiogenic factors. The physiologic roles of VEGF in humans include neovascularization and endometrium implantation, and in pathological processes VEGF has been involved in the initation, growth, and metastasis of tumors. In this book, the authors discuss the biology, regulation and clinical significance of VEGF. Topics include VEGF signaling and multi-drug resistance transporter (ABCB1); clinical imaging of tumor vascularity as a biomarker during anti-VEGF therapy; VEGF and kidney cancer; the effect of VEGF on oocyte maturation and embryo development of bovine and ovine in vitro and its mechanisms; physiological functions of VEGF in the retina; VEGF in the regulation of gingival venule diameter under physiological and pathological circumstances; regulation of VEGF expression by progesterone and estradiol in normal and cancer cells; ethanol stimulated angiogenesis via VEGF and protection from ischemia and reperfusion injury; and the role of VEGF in major depression.
Critical Role Of Anti Angiogenesis And Vegf Inhibition In Colorectal Cancer
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Author : Eduardo Diaz-Rubio
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 2005
Critical Role Of Anti Angiogenesis And Vegf Inhibition In Colorectal Cancer written by Eduardo Diaz-Rubio and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.