Vertebral Metastases


Vertebral Metastases
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Vertebral Metastases


Vertebral Metastases
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Author : Vincent Pointillart
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14

Vertebral Metastases written by Vincent Pointillart and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Medical categories.


Tumors cells no longer confined to an affected organ can be released through lymph and the blood stream, disseminate and form metastases. Metastases to the spine are frequent, may be painful and may occur in an isolated or multiple level manner, they may lead to structural failure of the spinal column and cause com pression of nerve structures resulting in progressive paralysis or in painful radi culopathies. The dinical evaluation as weIl as to tumor pathophysiology are weIl explai ned in two general chapters and then each specific primary tumor is analyzed in a specific chapter. The choice was made to offer a multidisciplinary approach. One may thus find similar aspects repeated in different chapters, yet this is ne ces sary since each part of this textbook can be used as a specific reference. I was impressed by the carefully detailed humane approach to the patient information with care for the patient's dignity. Truthful information is explained dearly enough to give all the elements the patient needs to understand and accept neces sary treatments with a responsible attitude. Previously, when confronted with a patient suffering from a debilitating spine metastasis of a malignant tumor it has been almost always too late to offer anything more than compassionate ineffica cy. Surgical treatment was balanced with life expectancy and then only rarely indicated in certain specific cases.



Metastatic Spine Disease


Metastatic Spine Disease
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Author : Rex A. W. Marco
language : en
Publisher: Springer
Release Date : 2018-05-24

Metastatic Spine Disease written by Rex A. W. Marco and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-24 with Medical categories.


This comprehensive text focuses exclusively on the management of metastatic spinal disease, evaluating the most recent literature and providing patient-centered treatment algorithms. Beginning with initial imaging, classification and clinical decision-making, the spine is approached anatomically from the upper cervical to the sacrum, describing the unique considerations and approaches appropriate to each region, such as laminectomy and stabilization, en bloc spondylectomy and resection and reconstruction. Less invasive and minimally invasive approaches are discussed throughout the text. Radiation therapy modalities and other adjuvant treatments are also discussed, as well as reconstructive flap coverage and the management of complications. The spinal column is the most common site of metastatic cancer, and a multidisciplinary approach is required to provide patients with reasonable management options to prevent and treat the disabling symptoms caused by this debilitating condition. This compendium of experience from thought leaders in the treatment of metastatic spine disease will provide spine surgeons, oncologists, radiation oncologists, physiatrists and palliative care specialists with up-to-date information to guide their patients through the multidisciplinary management of metastatic spinal disease.



Cancer In The Spine


Cancer In The Spine
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Author : Robert F. McLain
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-08-17

Cancer In The Spine written by Robert F. McLain and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-17 with Medical categories.


Distinguished physicians and researchers from prestigious Cancer Centers around the world offer their expertise in current and innovative management of cancer in the spine. These authors bring together the latest thinking from diverse fields of medicine to provide, in one volume, a guide to coordinated management of all aspects of spinal tumors covering chemo- and radiation therapy, pain management, diagnostic radiology, as well as reconstructive surgery and palliative care. Highlights include management of vertebral metastases, innovations in radiotherapy, treatment of pathological fractures, curative strategies for primary malignancies, as well as a guide to pain management and end-of-life care.



Bone Metastases


Bone Metastases
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Author : Vassilios Vassiliou
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-19

Bone Metastases written by Vassilios Vassiliou and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-19 with Medical categories.


The second edition of this book serves both as an introductory and reference book focusing on the field of metastatic bone disease. Featuring contributions from experts in the field, this volume describes the molecular and cellular mechanisms involved in the formation of bone metastases, presents the newer advances made in the understanding of the clinical picture and symptoms of patients, analyses the role of bone markers in research and clinical practice and deals with all aspects of imaging modalities applied for the detection and evaluation of bone metastases. Moreover, the use of all available treatment methods, such as radiotherapy, surgery and systemic treatments for the management of patients with metastatic bone disease is discussed in detail. Overall this volume presents a thorough overview of all aspects of metastatic bone disease and provides a comprehensive and concise information resource for researchers, oncologists, orthopaedic surgeons and clinicians dealing with patients with metastatic bone disease.



Bone Metastases


Bone Metastases
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Author : Dominique G. Poitout
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

Bone Metastases written by Dominique G. Poitout and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.


An introductory text on bone metastases written by experts from various disciplines. It covers the basic principles of surgery in bone cancer, classification, medical treatment, radiotherapy, surgical treatment, incidence and pain relief. The steady progress in diagnosis and treatment of bone cancer in the last decade has dramatically changed the prognosis of cancer patients, improving significantly the overall survival rate and quality of life. Multidisciplinary treatments that combine surgery, radiotherapy and chemotherapy, as described in this book, show significantly improved results and an above average survival rate. Some hematologic malignancies that involve bone may be cured with systemic chemotherapy or radiotherapy, but for most patients with bone metastases, pain relief is the goal of therapy.



Bone Metastases


Bone Metastases
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Author : Robert D. Rubens
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Bone Metastases written by Robert D. Rubens and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Bone Metastases brings together the many recent developments that are gradually improving the prospects for patients with secondary involvement of the skeleton in a primary cancer elsewhere. The morbidity from bone metastases is extensive, and the palliative and supportive treatment that sufferers require for many months or even years constitutes a major health problem. A multidisciplinary approach is essential since a variety of specialists are involved: radiation and medical oncologists, general and orthopaedic surgeons, general physicians, radiologists and nuclear medicine physicians, symptom control and terminal care specialists. The book's editors, themselves authorities in the fields of oncology and bone disease respectively, have brought together experts from all these disciplines to provide comprehensive coverage of metastatic bone disease. They cover the biology and pathophysiology, hypercalcaemia, imaging, assessment of response to treatment, types of treatment (systemic, radiotherapy, surgery), and symptomatic and supportive care. Particularly new approaches included are magnetic resonance imaging, the assessment of skeletal response and isotope therapy.



Development Of Guidelines For The Prophylactic Treatment Of Metastatically Involved Vertebral Bodies


Development Of Guidelines For The Prophylactic Treatment Of Metastatically Involved Vertebral Bodies
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Author : Cari Marisa Whyne
language : en
Publisher: Ann Arbor, Mich. : University Microfilms International
Release Date : 1999

Development Of Guidelines For The Prophylactic Treatment Of Metastatically Involved Vertebral Bodies written by Cari Marisa Whyne and has been published by Ann Arbor, Mich. : University Microfilms International this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.


Up to 1/3 of all cancer patients develop metastases to the spinal column and over 50% of spinal metastases with neurologic manifestations in females are found to arise from primary breast neoplasms (3). Burst fracture can arise in such bones compromised by tumor and is deemed one of the most difficult injuries of the spine to treat successfully, in part because the exact injury mechanism is not well understood. Using a combination of finite element modeling, materials and mechanical testing we aim to quantify fracture risk in metastatically involved vertebral bodies in order to both understand the mechanism of such fractures and develop a definitive set of clinical guidelines for the prophylactic treatment vertebral body metastases. To this end, we have developed an experimental protocol to analyze biphasic material properties of tumor specimens. We have constructed a poroelastic two-dimensional axis-symmetric finite element model of the vertebral body and adjacent intervertebral disc which has enabled us to parametrically assess the effects of rate dependence on vertebral body strength and validate the importance of utilizing poroelastic theory in the consideration of metastatic involvement. This progress provides us the needed basis for our three- dimensional modeling and experimental validation necessary to quantify burst fracture risk.



Management Of Bone Metastases


Management Of Bone Metastases
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Author : Vincenzo Denaro
language : en
Publisher: Springer
Release Date : 2018-07-25

Management Of Bone Metastases written by Vincenzo Denaro and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-25 with Medical categories.


This highly informative book provides a comprehensive, up-to-date and practical reference for daily clinical practice in the management of patients affected by bone metastases. Written by renowned orthopedic surgeons and leading doctors in the respective fields of expertise, it offers a transversal review of the current medical and surgical treatments to allow a real interdisciplinary approach to the oncologic patient according to the highest current standards. The book illustrates all the fundamental medical treatments for metastatic bone diseases and provides an overview of pathology issues related to this condition. An entire section is devoted to main different methods of patients approach. It also provides guidance on all current surgical procedures and minimally invasive treatment techniques. Using a common language and recognizing the different osteoncologic competences, this work allows surgeons, oncologists, radiologists, pathologists and physiatricians to update their expertise and broaden their understanding of how a real team approach can improve the management of these oncology patients.



Vertebral Tumors


Vertebral Tumors
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Author : Robert Gunzburg
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2008

Vertebral Tumors written by Robert Gunzburg and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.


This volume is a comprehensive review of the state of the art in the management of spinal tumors. Leading experts from the United States, Europe, and India present the latest concepts and findings on the epidemiology, classification, diagnosis, radiation therapy, and surgical treatment of primary and metastatic tumors of the spine. A major portion of the book focuses on current strategies for surgical treatment.



Bone Metastases


Bone Metastases
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Author : Maria Teresa Valenti
language : en
Publisher: Frontiers Media SA
Release Date : 2021-09-28

Bone Metastases written by Maria Teresa Valenti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-28 with Science categories.