Viral Fitness And Evolution
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Viral Fitness And Evolution
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Author : Esteban Domingo
language : en
Publisher: Springer Nature
Release Date : 2023-01-02
Viral Fitness And Evolution written by Esteban Domingo and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-02 with Medical categories.
This book unifies general concepts of plant and animal virus evolution and covers a broad range of topics related to theoretical and experimental aspects of virus population dynamics and viral fitness. Timely topics such as viral mechanisms to cope with antiviral agents, the adaptability of the virus to new hosts, emergence of new viral phenotypes, and the connections between short- and long-term virus evolution are included. By comparing plant and animal viruses, universal mechanisms responsible for fitness variations, viral emergence and disease mechanisms are explored. Although emphasis is put on specific plant and human viral pathogens, relevant similarities and differences to other viruses are highlighted. Additionally, readers will learn more about the adaptability of coronaviruses, including the recently emerged SARS-CoV-2, the causative agent of the COVID-19 pandemic. The book is aimed at students and scientists interested in basic and applied aspects of plant and animal virus population dynamics and evolution.
Origin And Evolution Of Viruses
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Author : Esteban Domingo
language : en
Publisher: Elsevier
Release Date : 2008-06-23
Origin And Evolution Of Viruses written by Esteban Domingo and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-23 with Science categories.
New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases. NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts
The Evolution And Emergence Of Rna Viruses
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Author : Edward C. Holmes
language : en
Publisher: Oxford University Press
Release Date : 2009-06-25
The Evolution And Emergence Of Rna Viruses written by Edward C. Holmes and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-25 with Language Arts & Disciplines categories.
While the study of viral evolution has developed rapidly in the last 30 years, little attention has been directed toward linking the mechanisms of viral evolution to the epidemiological outcomes of these processes. This book intends to fill this gap by considering the patterns and processes of viral evolution at all its spatial and temporal scales.
Fitness Landscape Red Queen Evolutionary Enigmas And Applications To Virology
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Author : Igor M. Rouzine
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2023-09-18
Fitness Landscape Red Queen Evolutionary Enigmas And Applications To Virology written by Igor M. Rouzine and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-18 with Mathematics categories.
Virus As Populations
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Author : Esteban Domingo
language : en
Publisher: Academic Press
Release Date : 2019-11-06
Virus As Populations written by Esteban Domingo and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-06 with Science categories.
Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. Features current views on key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes
Virus As Populations
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Author : Esteban Domingo
language : en
Publisher: Academic Press
Release Date : 2015-09-25
Virus As Populations written by Esteban Domingo and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-25 with Science categories.
Virus as Populations: Composition, Complexity, Dynamics, and Biological Implications explains fundamental concepts that arise from regarding viruses as complex populations when replicating in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, probability to be transmitted or response to treatment, depend on virus population numbers and in the variations of such population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, new antiviral strategies such as lethal mutagenesis, and extensions of population heterogeneity to nonviral systems are included. These main concepts of the book are framed in recent observations on general virus diversity derived from metagenomic studies, and current views on the origin of viruses and the role of viruses in the evolution of the biosphere. Features current views on the key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes
Crystallographic Analysis Of The Molecular Evolution Of Hiv 1 Proteinase
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Author : Aida Baharuddin
language : en
Publisher:
Release Date : 2007
Crystallographic Analysis Of The Molecular Evolution Of Hiv 1 Proteinase written by Aida Baharuddin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
Quasispecies Concept And Implications For Virology
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Author : Esteban Domingo
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-02-19
Quasispecies Concept And Implications For Virology written by Esteban Domingo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-02-19 with Medical categories.
Continuous genetic variation and selection of virus subpopulations in the course of RNA virus replications are intimately related to viral disease mechanisms. The central topics of this volume are the origins of the quasispecies concept, and the implications of quasispecies dynamics for viral populations.
Quasispecies And Rna Virus Evolution
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Author : Esteban Domingo
language : en
Publisher:
Release Date : 2001
Quasispecies And Rna Virus Evolution written by Esteban Domingo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Medical categories.
Viruses As Complex Adaptive Systems
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Author : Ricard Solé
language : en
Publisher: Princeton University Press
Release Date : 2018-12-11
Viruses As Complex Adaptive Systems written by Ricard Solé and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-11 with Science categories.
How complex systems theory sheds new light on the adaptive dynamics of viral populations Viruses are everywhere, infecting all sorts of living organisms, from the tiniest bacteria to the largest mammals. Many are harmful parasites, but viruses also play a major role as drivers of our evolution as a species and are essential regulators of the composition and complexity of ecosystems on a global scale. This concise book draws on complex systems theory to provide a fresh look at viral origins, populations, and evolution, and the coevolutionary dynamics of viruses and their hosts. New viruses continue to emerge that threaten people, crops, and farm animals. Viruses constantly evade our immune systems, and antiviral therapies and vaccination campaigns can be powerless against them. These unique characteristics of virus biology are a consequence of their tremendous evolutionary potential, which enables viruses to quickly adapt to any environmental challenge. Ricard Solé and Santiago Elena present a unified framework for understanding viruses as complex adaptive systems. They show how the application of complex systems theory to viral dynamics has provided new insights into the development of AIDS in patients infected with HIV-1, the emergence of new antigenic variants of the influenza A virus, and other cutting-edge advances. Essential reading for biologists, physicists, and mathematicians interested in complexity, Viruses as Complex Adaptive Systems also extends the analogy of viruses to the evolution of other replicators such as computer viruses, cancer, and languages.
