Viral Transformation And Endogenous Viruses
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Viral Transformation And Endogenous Viruses
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Author : Albert Kaplan
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Viral Transformation And Endogenous Viruses written by Albert Kaplan and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.
Viral Transformation and Endogenous Viruses is a collection of papers presented at the symposium on ""Viral Transformation and Endogenous Viruses"" held at Vanderbilt University on April 1-2, 1974. Contributors discuss the viral function(s) responsible for the transformation of the cells that are infected with oncogenic viruses, emphasizing the type of changes that characterize transformed cells and the regulatory mechanisms that are altered after malignant transformations. This volume is organized into 10 chapters and begins with an overview of DNA-containing tumor viruses, particularly Simian Virus 40 (SV40) and its mutants with DNA deletions, insertions, and duplications. The integration and transcription of adenovirus DNA is considered, along with the characteristics of temperature-sensitive mutants of these viruses. The reader is then introduced to the chemistry and biology of RNA-containing tumor viruses, which are useful reagents to study neoplastic transformation both in vivo and in vitro. A major aspect of these viruses concerns the analysis of their genome at the chemical and genetic levels. The last part of the book is devoted to biochemical and genetic analyses of endogenous viruses isolated from avian cells. This book is a valuable resource for scientists and investigators in fields such as pathology, molecular virology, molecular biology, microbiology, oncology, and biochemistry.
Retrovirus Genes In Lymphocyte Function And Growth
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Author : E. Wecker
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Retrovirus Genes In Lymphocyte Function And Growth written by E. Wecker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
All but one* of the following articles represent comprehensive reports on a workshop held between 7 and 9 May 1981 at the Institute of Virology and Immunobiology, University of Wfuzburg, Federal Republic of Germany. The title of the workshop was "The Involvement of Endogenous Retroviruses inN ormalFunction and Pathological Growth of Lymphocytes." Rather than collecting and printing manuscripts of the individual communications, the organizers asked selected parti cipants to write, after the workshop, concise articles each compris ing several contributions and discussions on major topics. In so doing, we hope to present to a larger audience a synopsis of the various information and views exchanged at the meeting. Such a procedure seemed the more appropriate as the workshop was intended to bring together specialists from two rather diverse fields: RNA-tumor virology and immunobiology. While this created some initial problems of terminology, it was quite effective in making representatives of one field more aware of the significance and the contributions ofthe other. It also great ly contributed to realization of the complexity of the problems involved in virus-induced leukemogenesis.
The Nature And Organization Of Retroviral Genes In Animal Cells
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Author : David R. Strayer
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-07
The Nature And Organization Of Retroviral Genes In Animal Cells written by David R. Strayer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-07 with Medical categories.
l RNA tumor viruses have become increasingly utilized in studies of cellular transformation and gene regulation. The genes of retroviruses exist in two forms; as extrachromosomal, RNA-containing, infectious particles and as DNA pro 2 viruses stably associated with cell genes. Components from the extracellular form can be collected in large quantity and purified for the preparation of molec ular probes. These probes can be used to dissect the sequence of events required for the establishment and expression of the integrated form. Furthermore the 2 genomes of retroviruses originated from normal cell genes, genes called virogenes • The nucleic acid and protein probes isolated from these viruses are therefore useful for studying the nature and expression of this normal cell gene and in elucidating the physiological role of its products. RNA tumor viruses perhaps offer us one of the most complete sets of biochemical reagents and biological responses for examining gene regulation in vertebrates and for studying the consequences of aberrant gene regulation on cell growth in tissue culture and in animals. Further more, there is an increasing conviction that virogenes play an important role in normal development and/or differentiation (RISSER, STOCKERT and OLD, 1978). Consequently, there is a growing feeling that DNA proviruses are altered viro genes and are capable of interfering with normal development or differentiation, causing reprogrammed growth or the incapacity to specialize.
Human Retroviruses
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Author : Bryan Cullen
language : en
Publisher: Oxford University Press
Release Date : 1993
Human Retroviruses written by Bryan Cullen and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Gene Expression Regulation. categories.
The first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.
Modern Trends In Human Leukemia Iv
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Author : R. Neth
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Modern Trends In Human Leukemia Iv written by R. Neth and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Organized on behalf of the Deutsche Gesellschaft für Hämatologie und Onkologie. Wilsede, June 21-23, 1982
Discovering Retroviruses
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Author : Anna Marie Skalka
language : en
Publisher: Harvard University Press
Release Date : 2018-10-22
Discovering Retroviruses written by Anna Marie Skalka and has been published by Harvard University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-22 with Science categories.
Eight percent of our DNA contains retroviruses that are millions of years old. Anna Marie Skalka explains how our evolving knowledge of these particles has advanced genetic engineering, gene delivery systems, and precision medicine. Retroviruses cause disease but also hold clues to prevention and treatment possibilities that are anything but retro.
Retroviruses 1
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Author : P.K. Vogt
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Retroviruses 1 written by P.K. Vogt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
1. 1 Scope of the Review This review was intended initially as a reference source for those interested in the origins and fITst descriptions ofthe defective avian sarcoma viruses. Quite a few of these viruses have been characterized in the past few years and their varied nomenclature according to source, discoverer, date of isolation or biological properties could result in some con fusion among those attempting to follow the literature. Information will be included on the molecular biology of the sarcoma viruses, rather more of which is available than when the review was fITst conceived, although in this respect the review will inevitably be out of date by the time of publication. If any bias of content is introduced, this will be towards a more detailed coverage of the author's own area of interest, the gene products of the defective sarcoma viruses. Rous sarcoma virus (RSV) serves as the model for much of this work and will frequently be referred to for comparative purposes, as will the mammalian defective transforming viruses. Recent reviews provide more complete coverage of these topics (l-4a). This review is complemented by a discussion ofthe avian acute leukaemia viruses, which appears elsewhere in this volume [5]. As will be seen, concentrating primarily on the defective sarcoma viruses and comparing them to RSV can be justified in terms of their biochemical properties as well as their similar biology.
Oncogenic Viruses Advances In Research And Treatment 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Oncogenic Viruses Advances In Research And Treatment 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Oncogenic Viruses: Advances in Research and Treatment: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Oncogenic Viruses in a concise format. The editors have built Oncogenic Viruses: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Oncogenic Viruses in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Oncogenic Viruses: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
International Symposium Retroviruses And Human Pathology
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Author : Robert C. Gallo
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
International Symposium Retroviruses And Human Pathology written by Robert C. Gallo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presence of retroviruses in numerous animal species and proved their etiological role in some related diseases. Corresponding findings in humans were somewhat discouraging. Although financial support for this line· of research declined, a few dedicated retrovirologists survived and continued to collect more biological information and technological expertise that opened a new approach to the search for a human retrovirus. The rewards came with the discovery that the genes responsible for neoplastic transformation (oncogenes) are of cellular origin and can be shuttled about by retroviruses, and with the identification of a new family of Human T-cell Lymphotrophic retroViruses (HTLV) from patients with diseases ranging from leukemia to the acquired immunodeficiency syndrome (AIDS). An understanding of the role and significance of retroviruses in human pathology requires basic knowledge of the major animal systems studied. With this perspective in mind, we present here a survey that includes general overviews, minireviews on each animal system studied with selected experimental reports and, finally, a stimulating review of the field of human retrovirology by many of the pioneer scientists who created it. We are especially grateful to Profs. C. A. Romanzi and G. C. Schito for promoting the organization of the Symposium. On behalf of the Sym posium Committee, we thank E. Soeri, L. Casarino, G. P. Gesu, M.
Retroviruses And Insights Into Cancer
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Author : Jaquelin Dudley
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-22
Retroviruses And Insights Into Cancer written by Jaquelin Dudley and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-22 with Medical categories.
This book will contain a series of review articles that focus on retroviral models of human and animal cancers. Each article will be written by an expert in the field of retrovirology. The reviews will summarize current work on a particular retrovirus, with particular emphasis on the relevance of this research to human disease.