Viruses And Interferon
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Viruses And Interferon
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Author : Karen Mossman
language : en
Publisher: Caister Academic Press Limited
Release Date : 2011
Viruses And Interferon written by Karen Mossman and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.
Interferons (IFNs) play pivotal roles in shaping the immune responses in mammals and are particularly important for the control of viral infections and cell growth, and immune regulation. These proteins rapidly induce an 'anti-viral state' in cells that surround infected cells. In order to survive, viruses have evolved multiple strategies to evade the anti-viral effects of IFNs. Elucidating the molecular and cellular biology of the virus-interferon interaction is key to understanding issues such as viral pathogenesis, latency, and the development of novel antivirals. In this book, a panel of international experts reviews the current hot-topics, producing a timely overview of this exciting field. The book opens with a chapter that comprehensively reviews the antiviral effects of extracellular double-stranded RNA, the 'viral toxin'. This is followed by chapters that review the properties of type I and type III interferons, and the role of interferon-stimulated genes. The next five chapters are devoted to understanding the diverse strategies used by clinically relevant human viruses to subvert host interferon responses. The closing chapter provides an interesting overview of the clinical application of interferon as antiviral and anticancer agents. Essential reading for every scientist involved in interferon or antiviral research and a recommended text for all virology laboratories.
Viruses And Interferon
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Author : Karen Mossman
language : en
Publisher:
Release Date : 2011
Viruses And Interferon written by Karen Mossman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.
In this book, a panel of international experts reviews the current hot-topics, producing a timely overview of this exciting field. The book opens with a chapter that comprehensively reviews the antiviral effects of extracellular double-stranded RNA, the 'viral toxin'. This is followed by chapters that review the properties of type I and type III interferons, and the role of interferon-stimulated genes. The next five chapters are devoted to understanding the diverse strategies used by clinically relevant human viruses to subvert host interferon responses. The closing chapter provides an interes.
Viral Interference And Interferon
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Author : R. D. Andrews
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Viral Interference And Interferon written by R. D. Andrews and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
Viral Interference and Interferon details the developments in the control of virus infections by natural means. The book is comprised of eight chapters that discuss various aspects of interferon. The text first introduces the main concepts of the subject matter. The succeeding chapter discusses various concerns about interferon, including the production, nature, mechanisms, and mode of actions. The book also covers interferon in humans and animals, and its significance. The text will be of great use to students of microbiology, virology, genetics, and immunology.
Effects Of Interferon On Cells Viruses And The Immune System
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Author : A. Geraldes
language : en
Publisher:
Release Date : 1975
Effects Of Interferon On Cells Viruses And The Immune System written by A. Geraldes and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Cellular immunity categories.
Interferons And Interferon Inducers
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Author : Norman B. Finter
language : en
Publisher:
Release Date : 1973
Interferons And Interferon Inducers written by Norman B. Finter and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1973 with Medical categories.
Virus And Interferon
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Author : Han Xiao
language : en
Publisher:
Release Date : 2011
Virus And Interferon written by Han Xiao and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Antiviral agents categories.
Antiviral Substances Including Interferon
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Author :
language : en
Publisher:
Release Date : 1977
Antiviral Substances Including Interferon written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Interferon categories.
Gamma Interferon In Antiviral Defense
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Author : Gunasegaran Karupiah
language : en
Publisher: Landes Bioscience
Release Date : 1997
Gamma Interferon In Antiviral Defense written by Gunasegaran Karupiah and has been published by Landes Bioscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.
Interferons A Primer
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Author : Robert Friedman
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Interferons A Primer written by Robert Friedman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.
Interferons: A Primer covers general information on interferon, including analysis, purification, production, properties, mechanism of action, and clinical uses. Organized into 10 chapters, the book starts with a short history of interferon’s discovery by Isaacs and Lindenmann, followed by topics on assays for interferon, such as factors affecting interferon assays and rapid biological assay. Chapters 3 to 6 discuss the purification, properties, production, antiviral action, and other functions of interferon. Chapters 7 and 8 examine the recovery from viral infection and clinical uses of interferon, with emphasis on treatment of human cancer. The concluding chapters focus on the application of interferon studies on two revolutionizing fields of biology, namely, the cloning of animal genes in microorganisms and the production of monoclonal antibodies. This book is intended for students, scientists, physicians, or educated laypersons who wish to know something about interferons, but do not plan carrying out research in this area.
Antiviral Drugs And Interferon The Molecular Basis Of Their Activity
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Author : Yechiel Becker
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Antiviral Drugs And Interferon The Molecular Basis Of Their Activity written by Yechiel Becker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Research on antiviral drugs and their mode of action in infected cells. in animals and in man. has led to a better understanding of the molecular pro cesses involved in virus replication. Screeninq of large numbers of natural and semisynthetic compounds resulted in the characterization of certain sub stances that had a limited efficiency as antiviral druqs. A few chemically synthesized compounds were also found to be effective as antiviral agents in the chemotherapy of human virus diseases. A major difficulty in the develop ment of effective antiviral agents has been the lack of selectivity. and toxicity for uninfected cells. of drugs that effectively inhibited virus replication in vitro. Further understanding of the molecular processes of virus replication in infected cells has resulted in the development of new antivirals directed at virus-coded enzymes or proteins. Recent studies on antivirals that are activated by the herpes simplex virus type l-coded thy midine kinase from a prod rug to an antiviral drug have opened new directions in the development of effective antiviral drugs. The present book deals with a number of antiviral drugs effective against herpes simplex viruses and provides some insight into the molecular aspects of virus replication. It also throws light on the new approaches to the development of antiviral drugs. The molecular basis of the antiviral activity of new and known drugs and their possible use in chemotherapy of viral disease are presented in this book.