Who Guidelines On Tularaemia
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Who Guidelines On Tularaemia
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2007-12-15
Who Guidelines On Tularaemia written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-15 with Medical categories.
Tularaemia is a bacterial zoonotic disease of the northern hemisphere. The bacterium (Francisella tularensis) is highly virulent for humans and a range of animals such as rodents hares and rabbits. Humans can infect themselves by direct contact with infected animals by arthropod bites by ingestion of contaminated water or food or by inhalation of infective aerosols. There is no human-to-human transmission. In addition to its natural occurrence F. tularensis evokes great concern as a potential bioterrorism agent. F. tularensis subspecies tularensis is one of the most infectious pathogens known in human medicine. In order to avoid laboratory-associated infection safety measures are needed and consequently clinical laboratories do not generally accept specimens for culture. However since clinical management of cases depends on early recognition there is an urgent need for diagnostic services. This first edition of WHO Guidelines on tularaemia provides background information on the disease describes the current best practices for its diagnosis and treatments in humans suggests measures to be taken in case of epidemics and provides guidance on how to handle F. tularensis in the laboratory. The target audience includes clinicians laboratory personnel public health workers veterinarians and any other person with an interest in zoonoses.
Who Guidelines On Tularaemia
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Author : Organizzazione mondiale della sanità
language : en
Publisher:
Release Date : 2008
Who Guidelines On Tularaemia written by Organizzazione mondiale della sanità and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
Human Diseases From Wildlife
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Author : Michael R. Conover
language : en
Publisher: CRC Press
Release Date : 2014-09-18
Human Diseases From Wildlife written by Michael R. Conover and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-18 with Medical categories.
Human Diseases from Wildlife presents information on the most prevalent and serious zoonotic diseases in the US and Canada, some of which have been national headline news like anthrax, influenza, and West Nile virus. Diseases that are caused by pathogens with the ability to infect both humans and animals are known as zoonotic diseases, which litera
Tularemia Epidemiology Ecology Genomics Immunity And Pathogenesis
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Author : Marina Santic
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-22
Tularemia Epidemiology Ecology Genomics Immunity And Pathogenesis written by Marina Santic and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-22 with categories.
Tularemia is a severe anthropozoonosis caused by Francisella tularensis. The genus Francisella contains five species: F. tularensis, F. philomiragia, F. hispaniensis, F. noatunensis and F. novicida. First described in 1911 in Tulare County, California, it has since been reported worldwide, capable of infecting more than 250 vertebrates and invertebrate species. Although it causes disease in various animal species, no animal has been identified as a main reservoir of this pathogen. Humans acquire infection by several routes, including direct contact with infected animals, ingestion of water or food contaminated by infected animals, exposure to infected arthropod vectors or by inhalation of infective aerosols resulting in pneumonic, oropharyngeal, glandular, ulceroglandular or oculoglandular tularemia. The clinical presentation of human tularemia depends on route of the infection, the causative Francisella strain, and the immune response of the host. A live attenuated vaccine (LVS) has been available for more than 50 years, however, unlikely to become licensed in the future due to a lack of understanding of the genetic basis for its attenuation. Due to the ease of its dissemination, its multiple routes of infection, its low dose of infection, severe morbidity, and high rate of mortality, F. tularensis subsp. tularensis has been classified as a category A bioterrorism agent by the CDC. Many virulence factors of F. tularensis have been discovered and investigated, but more in-depth host pathogen interaction analyses are needed to define mechanisms of pathogenicity and virulence of this unique pathogen.
Hunter S Tropical Medicine And Emerging Infectious Diseases E Book
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Author : Edward T Ryan
language : en
Publisher: Elsevier Health Sciences
Release Date : 2019-03-25
Hunter S Tropical Medicine And Emerging Infectious Diseases E Book written by Edward T Ryan and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-25 with Medical categories.
New emerging diseases, new diagnostic modalities for resource-poor settings, new vaccine schedules ... all significant, recent developments in the fast-changing field of tropical medicine. Hunter’s Tropical Medicine and Emerging Infectious Diseases, 10th Edition, keeps you up to date with everything from infectious diseases and environmental issues through poisoning and toxicology, animal injuries, and nutritional and micronutrient deficiencies that result from traveling to tropical or subtropical regions. This comprehensive resource provides authoritative clinical guidance, useful statistics, and chapters covering organs, skills, and services, as well as traditional pathogen-based content. You’ll get a full understanding of how to recognize and treat these unique health issues, no matter how widespread or difficult to control. Includes important updates on malaria, leishmaniasis, tuberculosis and HIV, as well as coverage of Ebola, Zika virus, Chikungunya, and other emerging pathogens. Provides new vaccine schedules and information on implementation. Features five all-new chapters: Neglected Tropical Diseases: Public Health Control Programs and Mass Drug Administration; Health System and Health Care Delivery; Zika; Medical Entomology; and Vector Control – as well as 250 new images throughout. Presents the common characteristics and methods of transmission for each tropical disease, as well as the applicable diagnosis, treatment, control, and disease prevention techniques. Contains skills-based chapters such as dentistry, neonatal pediatrics and ICMI, and surgery in the tropics, and service-based chapters such as transfusion in resource-poor settings, microbiology, and imaging. Discusses maladies such as delusional parasitosis that are often seen in returning travelers, including those making international adoptions, transplant patients, medical tourists, and more.
Molecular Detection Of Human Bacterial Pathogens
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Author : Dongyou Liu
language : en
Publisher: CRC Press
Release Date : 2011-04-18
Molecular Detection Of Human Bacterial Pathogens written by Dongyou Liu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-18 with Medical categories.
As more original molecular protocols and subsequent modifications are described in the literature, it has become difficult for those not directly involved in the development of these protocols to know which are most appropriate to adopt for accurate identification of bacterial pathogens. Molecular Detection of Human Bacterial Pathogens addresses this issue, with international scientists in respective bacterial pathogen research and diagnosis providing expert summaries on current diagnostic approaches for major human bacterial pathogens. Each chapter consists of a brief review on the classification, epidemiology, clinical features, and diagnosis of an important pathogenic bacterial genus, an outline of clinical sample collection and preparation procedures, a selection of representative stepwise molecular protocols, and a discussion on further research requirements relating to improved diagnosis. This book represents a reliable and convenient reference on molecular detection and identification of major human bacterial pathogens; an indispensable tool for upcoming and experienced medical, veterinary, and industrial laboratory scientists engaged in bacterial characterization; and an essential textbook for undergraduate and graduate students in microbiology.
Treatment Of Skin Disease E Book
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Author : Mark G. Lebwohl
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-09-19
Treatment Of Skin Disease E Book written by Mark G. Lebwohl and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-19 with Medical categories.
Covering more than 250 of the most common dermatologic conditions from A to Z, Treatment of Skin Disease, 5th Edition, by Drs. Mark G. Lebwohl, Warren R. Heymann, John Berth-Jones, and Ian Coulson, is your go-to resource for authoritative, evidence-based treatment strategies in your daily practice. This award-winning text provides guidance on the fast-moving dermatological therapy options for virtually any skin disease you’re likely to encounter, including third-line and unusual therapies when initial options have not been successful. Summaries of each treatment strategy are accompanied by detailed discussions of treatment choices, with ratings on a consistent scale ranging from clinical studies to anecdotal reports. Puts every possible therapeutic option at your disposal – including management strategies and first- to third-line therapies – for a truly complete guide to the vast array of dermatologic treatment options. Presents information in a consistent, tabular format, with checklists of diagnostic and investigative pearls and color-coded boxes for quick reference. Offers the combined knowledge and expertise of the world’s leading authorities in dermatology. Features eight all-new chapters on Atypical Fibroxanthoma, Confluent and Reticulated Papillomatosis, Cryopyrin Associated Periodic Syndromes (CAPS), Hypopigmented Dermatoses, Nail Psoriasis, Necrolytic Acral Erythema, Post-inflammatory Hyperpigmentation, and Regional Pain. Provides more than 250 full-color clinical images of skin diseases, most of which are new to this edition. Includes off-label uses, new treatments like therapeutic antibodies and hedgehog inhibitors, and new indications for existing treatments.
Manual Of Security Sensitive Microbes And Toxins
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Author : Dongyou Liu
language : en
Publisher: CRC Press
Release Date : 2014-04-08
Manual Of Security Sensitive Microbes And Toxins written by Dongyou Liu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-08 with Medical categories.
Security sensitive microbes (viruses, bacteria, fungi, and parasites) and toxins, which are often referred to as the select agents and toxins, have the capacity to cause serious illness and death in humans, animals, and plants. Throughout history, these microbes and toxins have been exploited in one form or another as biowarfare and bioterror agents that create fear and panic well beyond any actual physical damages they might cause. Manual of Security Sensitive Microbes and Toxins provides comprehensive, state-of-the-art coverage of microbes and toxins of biosecurity concern. The ultimate goal is to increase our awareness of these agents and enhance our preparedness against any future bio-emergencies. The book begins with an introduction containing a brief overview of the historical aspects of security sensitive microbes and toxins. This is followed by a concise summary of the current status in relation to the regulation of security sensitive microbes and toxins and a discussion of future development trends. The book is divided into seven parts: Microbes and Toxins Affecting Humans and Animals: Viruses Microbes and Toxins Affecting Human and Animals: Bacteria Microbes and Toxins Affecting Human and Animals: Fungus and Parasite Microbes and Toxins Affecting Human and Animals: Toxins Microbes Affecting Animals: Viruses Microbes Affecting Animals: Bacteria Microbes Affecting Plants Written by experts in the relevant areas of research, the chapters are authoritative reviews, each one covering a single microbe or toxin with respect to its classification, biology, epidemiology, pathogenesis, identification, diagnosis, treatment, and prevention. The chapters also discuss the limitations of our current knowledge and challenges relating to improved detection and control of the microbe or toxin.
New Anti Infective Strategies For Treatment Of Tularemia
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Author : Max Maurin
language : en
Publisher: Frontiers E-books
Release Date : 2014-11-21
New Anti Infective Strategies For Treatment Of Tularemia written by Max Maurin and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-21 with Infectious and parasitic diseases categories.
Francisella tularensis, the causative agent of tularemia, is a paradigm among human pathogens. This Gram-negative bacterium has an intracellular lifestyle, which probably reflects an adaptation to its natural animal and protozoa reservoirs. This is one of the most infectious agents in humans and animals; only a few bacteria are needed to induce a severe infection in both types of hosts. The clinical presentation and severity of human tularemia varies according to the portal of entry of bacteria, the bacterial inoculum, the virulence of the infecting strain, and the immune response of the host. Although most infections occur after direct inoculation of bacteria through the skin (through skin wounds or bites of arthropods), pneumonia due to inhalation of infected aerosols is the most feared of the clinical forms of the disease, particularly in the context of biological threat. Two subspecies are responsible for tularemia (subsp. tularensis and subsp. holarctica), and several clades have been described for each, which might be associated with changes in disease severity in humans. Tularemia is also more severe in people with an impaired immune response. No safe vaccine is currently available for prophylaxis of tularemia in humans. On the other hand, control of proliferation of F. tularensis in wildlife is not feasible. Thus, only the anti-infective agents are used for treatment and prophylaxis of human tularemia. The standard options include aminoglycosides (gentamicin), tetracyclines (eg, doxycycline) and fluoroquinolones (eg, ciprofloxacin). The selection of acquired resistance to these antibiotics in F. tularensis, especially in the context of a biological threat, may quickly limit the therapeutic options. New prophylactic and therapeutic alternatives must be developed rapidly. The present Research Topic focuses on potential new strategies for treatment of tularemia, including the development and evaluation of new compounds having proper antibacterial activity, reducing the virulence of F. tularensis or enhancing the immune host response.
Handbook Of Foodborne Diseases
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Author : Dongyou Liu
language : en
Publisher: CRC Press
Release Date : 2018-10-29
Handbook Of Foodborne Diseases written by Dongyou Liu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-29 with Medical categories.
Clearly linked to consumption of foods, beverages, and drinking water that contain pathogenic microbes, toxins, or other toxic agents, foodborne diseases have undergone a remarkable change of fortune in recent decades, from once rare and insignificant malaises to headline-grabbing and deadly outbreaks. Unquestionably, several factors have combined to make this happen. These include a prevailing demand for the convenience of ready-to-eat or heat-and-eat manufactured food products that allow ready entry and survival of some robust, temperature-insensitive microorganisms; a drastic reduction in the costs of air, sea, and road transportation that has taken some pathogenic microorganisms to where they were absent previously; an expanding world population that has stretched the boundary of human activity; and an ageing population whose weakened immune functions provide a fertile ground for opportunistic pathogens to invade and thrive. Given the diversity of causative agents (ranging from viruses, bacteria, yeasts, filamentous fungi, protozoa, helminthes, toxins, to toxic agents), and the ingenuity of pathogenic microbes to evolve through genetic reassortment, horizontal gene transfer, and/or random genetic mutation, it has become an enormous challenge to understand how foodborne agents are able to evade host immune defenses and induce diseases, and also to develop and apply innovative approaches for improved diagnosis, treatment, and prevention of foodborne diseases. Handbook of Foodborne Diseases summarizes the latest findings on more than 100 foodborne diseases and their causative agents. With contributions from international experts on foodborne pathogens, toxins, and toxic agents research, this volume provides state-of-the-art overviews on foodborne diseases in relation to their etiology, biology, epidemiology, clinical presentation, pathogenesis, diagnosis, treatment, and prevention. Apart from offering a comprehensive textbook for undergraduate and postgraduate students in food, medical, and veterinary microbiology, this volume constitutes a valuable reference on foodborne diseases for medical professionals and health authorities, and forms an informative educational resource for the general public.