Zbinden S Progress
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Fortschritte Der Arzneimittelforschung Progress In Drug Research Progr S Des Recherches Pharmaceutiques
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Author : JUCKER
language : en
Publisher: Birkhäuser
Release Date : 2013-03-08
Fortschritte Der Arzneimittelforschung Progress In Drug Research Progr S Des Recherches Pharmaceutiques written by JUCKER and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-08 with Science categories.
Zbinden S Progress
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Author : Christoph Simon
language : en
Publisher:
Release Date : 2012
Zbinden S Progress written by Christoph Simon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Older men categories.
"...little Odyssey, a little Ulysses; the story of one day's journey, skillfully playing in tandem with another, life-long journey."
Progress In Toxicology
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Author : Gerhard Zbinden
language : de
Publisher: Springer-Verlag
Release Date : 2013-03-07
Progress In Toxicology written by Gerhard Zbinden and has been published by Springer-Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-07 with Science categories.
THE STATE OF THE ART The recent seventies have not been good times for toxicologists. Public confidence in us is shaken, mostly as a consequence of an unhappy sequence of spectacular failures: we have been surprised by a tragic transplacental carcinogenic effect of diethylstilbestrol, an old and widely prescribed synthetic estrogen. We are confronted with a small epidemic of an unusual liver tumor, angiosarcoma, induced by a simple chemical, vinylchloride, whose insiduous toxic potential we failed to "recognize for years. Our clinical colleagues had to tell us about the ulcerogenic effect of as simple a substance as potassium chloride. We also just learned of an unusual toxic reaction, pseudolupus, developing in people taking a popular fixed-combination drug, venocuran~ Admit tedly, we could not have predicted this syndrome, even if we had con sidered the possibility. We are still unable (to continue this self-flagellation) to explain the relationship between the appetite suppressant arninorex and the sud denly increased occurrence of a lung disease posing as primary pulmonary hypertension. And worse yet, we have no way to evaluate a new deriva tive of this class, and to predict whether or not it, too, will produce the deadly condition. We still, to my knowledge, have no plausible ex planation why and how thalidomide caused phocomelia. Of course, we do diligently a set of teratological experiments with each new drug; we follow a protocol which has the blessing of all governmental regulatory agencies.
Progress In Chemokine Research
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Author : W. P. Linkes
language : en
Publisher: Nova Publishers
Release Date : 2007
Progress In Chemokine Research written by W. P. Linkes and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
Chemokines are the cytokines that may activate or chemoattract leukocytes. Each chemokine contains 65 ~ 120 amino acids, with molecular weight of 8-10 kD. Their receptors belong to G-protein-coupled receptors. Inflammatory chemokines are released from a wide variety of cells in response to bacterial infection, viruses and agents that cause physical damage such as silica or the urate crystals that occur in gout. They function mainly as chemoattractants for leukocytes, recruiting monocytes, neutrophils and other effector cells from the blood to sites of infection or damage. They can be released by many different cell types and serve to guide cells involved in innate immunity and also the lymphocytes of the adaptive immune system. The cells that are attracted by chemokines follow a signal of increasing chemokine concentration to the site of infection or tissue injury. Some chemokines also have roles in the development of lymphocytes, migration and angiogenesis (the growth of new blood vessels).Since the entry of HIV into host cells requires chemokine receptors, their antagonists are being developed to treat AIDS. This book presents leading research from around the globe in this field.
Progress In In Vitro Toxicology Volume 6
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Author : AM Goldberg (Ed)
language : en
Publisher:
Release Date : 1988
Progress In In Vitro Toxicology Volume 6 written by AM Goldberg (Ed) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with categories.
Progress In Drug Research
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Author :
language : en
Publisher: Birkhäuser
Release Date : 2012-12-06
Progress In Drug Research written by and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Hepatitis C virus (HCV) was first identified in 1989 as the etiologic agent of non-A, non-B hepatitis [1] and is currently recognized as the leading cause of chronic liver disease worldwide. In contrast to hepatitis B virus infection, in which only about 5% of adult infections become chronic, more than 80% of HCV-infected patients develop chronic hepatitis. Moreover, 20-50% of those persistently infected with HCV will develop liver cirrhosis and hepatocellu lar carcinoma (HCC) [2]. It is estimated that there are 10,000 deaths in the USA per year due to chronic liver failure or HCC [3]. In addition, HCV dis 25-50% of all liver transplants in US centers, and the ease is responsible for recurrence of HCV infection following liver transplantation is universal [4]. Typically, HCV disease emerges after a 10-20 year period during which symp toms, if they exist at all, are mild and non-specific. Although the prevalence varies greatly among different countries, it has been estimated that up to 170 million people (3% of the world's population), are infected with HCV [5]. A recent study in the USA found that 65% of all HCV-infected persons are 30 to 49 years old [6].
Progress In Optics
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Author :
language : en
Publisher: Elsevier
Release Date : 2001-12-17
Progress In Optics written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-12-17 with Science categories.
This volume presents six review articles devoted to various topics of current interest both in classical and in quantum optics. The first article, by S. Ya. Kilin, entitled "Quanta and Information", is concerned with a multidisciplinary subject which involves optics, information theory, programming and discrete mathematics. The second article, "Optical Solitons in Periodic Media with Resonant and Off-Resonant Nonlinearities", by G. Kurizki, A.E. Kozhekin, T. Optatrny and B. Malomed, reviews the properties of optical solitons in periodic nonlinear media. The article which follows deals with an effect and its inverse which is a manifestation of hindrance and enhancement, respectively, of the evolution of a quantum system by an external agent, such as a detection apparatus. The fourth article discusses the current status of a relatively new branch of physical optics, sometimes called singular optics. The next two articles respectively present a review of advances in two-photon interferometry and their relation to investigations of the foundations of quantum theory and an examination of transverse mode shaping and selection in laser resonators.
Progress In Optics
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Author : Emil Wolf
language : en
Publisher: Elsevier
Release Date : 2006-10-03
Progress In Optics written by Emil Wolf and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-03 with Science categories.
In the thirty-seven years that have gone by since the first volume of Progress in Optics was published, optics has become one of the most dynamic fields of science. At the time of inception of this series, the first lasers were only just becoming operational, holography was in its infancy, subjects such as fiber optics, integrated optics and optoelectronics did not exist and quantum optics was the domain of only a few physicists. The term photonics had not yet been coined. Today these fields are flourishing and have become areas of specialisation for many science and engineering students and numerous research workers and engineers throughout the world. Some of the advances in these fields have been recognized by awarding Nobel prizes to seven physicists in the last twenty years. The volumes in this series which have appeared up to now contain nearly 190 review articles by distinguished research workers, which have become permanent records for many important developments. They have helped optical scientists and optical engineers to stay abreast of their fields. There is no sign that developments in optics are slowing down or becoming less interesting. - Gaussian apodization and beam propagation - Electromagnetically-induced transparency - Three-dimensional electromagnetic fields - Quantum cryptography - Optical quantum cloning
International Union Of Pharmacology
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Author : Paul Turner
language : en
Publisher: Springer
Release Date : 2015-12-31
International Union Of Pharmacology written by Paul Turner and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-31 with Medical categories.
Coronary Vasculature
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Author : Robert J. Tomanek
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-10-19
Coronary Vasculature written by Robert J. Tomanek and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-19 with Medical categories.
Ischemic heart disease is the leading cause of morbidity and mortality in the developed world. The high metabolism and oxygen demand of the cardiac myocardium depends on both a high blood flow and a rich capillary density. For this reason, the growth of the coronary vasculature is vital, not only in early development, but also in the adult faced with various stresses. Novel technologies have enabled the discovery of the molecular mechanisms underlying the growth and assembly coronary vessels, and this volume covers the hierarchy of the coronary vasculature from its embryonic origins through its postnatal growth, adulthood, and senescence. Chapters address normal coronary development, coronary anomalies and their possible underlying developmental errors, coronary vessel adaptations to exercise training, aging, hypoxia, myocardial ischemia, and cardiac hypertrophy. This comprehensive overview of current research in coronary vessels and myocardial perfusion was written by Dr. Robert J. Tomanek, Emeritus Professor of Anatomy and Cell Biology at the University of Iowa. The book reviews, discusses, and integrates findings from various areas of coronary vasculature research, and as a result, will be a valuable reference source for cardiovascular scientists and physicians for many years to come.