Zebrafish Models For Human Disease Studies
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Zebrafish Models For Human Disease Studies
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Author : Liqing Zang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-04-04
Zebrafish Models For Human Disease Studies written by Liqing Zang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-04 with Science categories.
Animal Models For The Study Of Human Disease
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Author : Angela L. Shamchuk
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-29
Animal Models For The Study Of Human Disease written by Angela L. Shamchuk and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-29 with Medical categories.
Olfactory dysfunction, although caused by many factors including physical damage and genetic abnormalities, is an early stage symptom of several neurodegenerative diseases. Not only is the olfactory system subject to the specific histological abnormalities but patients also lose the capacities to detect, identify, and discriminate among odors. In addition to olfactory deficits, motor dysfunction is another prominent manifestation of these conditions. Recent studies have begun to create zebrafish (Danio rerio) models for neurodegenerative diseases. Despite successful execution, there remains a great deal of potential in testing the models using established methods of olfactory and motion assessment. This chapter discusses the current zebrafish models and suggests olfactory and motor endpoints for Parkinson's, Alzheimer's, Huntington's, multiple system atrophy, and amyotrophic lateral sclerosis.
Zebrafish In Development And Disease
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Author : Gokhan Dalgin
language : en
Publisher: Frontiers Media SA
Release Date : 2019-12-06
Zebrafish In Development And Disease written by Gokhan Dalgin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-06 with categories.
There are only a few vertebrate systems that can be used to model human diseases for biomedical discovery. The zebrafish model provides key advantages over existing models. Their externally developing embryos provide high-throughput non-invasive imaging, chemical screening, forward and reverse genetics, and their regeneration capacity make zebrafish a valuable system for novel discovery. Developmental studies using zebrafish has influenced discoveries in many human health-related conditions. This Research Topic covers all aspects of zebrafish studies, providing developmental mechanisms to human health conditions. The aim of the Research Topic was to foster a platform to bring all levels of zebrafish research including but not limited to development, disease, regeneration, drug screening, bioinformatics and Omics studies.
Zebrafish Model For Biomedical Research
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Author : Prasan R. Bhandari
language : en
Publisher: Springer Nature
Release Date : 2022-05-30
Zebrafish Model For Biomedical Research written by Prasan R. Bhandari and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-30 with Medical categories.
This book provides the latest information on the significance of zebrafish as an ideal model for researching the biomedical field, with references. This book also focused on the evidence of zebrafish as a model in cardiovascular, neurologic, psychiatric and metabolic research. In addition, the book also includes the research carried out on zebrafish in hepatic, renal, ophthalmic, and ENT related areas. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish models including specific research in the area of skin disorders, endocrine diseases, nutritional disorders, gastrointestinal, hematological disorders and cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and its suitability for modeling various diseases, providing a critical resource on the potential attributes of the zebrafish as a pharmacological model. In terms of scope, this book is a useful tool for young researchers, professors and pharmaceutical scientists for understanding the significance of zebrafish as an emerging pharmacological model that can significantly aid in the process of drug discovery and development.
Zebrafish At The Interface Of Development And Disease Research
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Author :
language : en
Publisher: Academic Press
Release Date : 2017-03-21
Zebrafish At The Interface Of Development And Disease Research written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-21 with Science categories.
There are many shared pathways that govern development and also can contribute to disease. Zebrafish have traditionally been used to study vertebrate development, and from decades of work in this system, we have learned details about developmental processes, genes and pathways that are implicated in disease. In each chapter of this book, we interweave how studying zebrafish development has informed our understanding of diseases from the immune system, to the kidney, liver, heart and others. The subject matter is unique - no single volume has pulled together the theme of development and disease with zebrafish as a centerpiece Leading experts in the field - all of them running zebrafish focused labs for each chapter
Zebrafish
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Author : James F. Amatruda
language : en
Publisher: Springer Nature
Release Date : 2023-09-05
Zebrafish written by James F. Amatruda and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-05 with Science categories.
This fully updated edition introduces new tools, models, and analytic insights that position the zebrafish even more strongly as an engine of discovery for developmental and disease biology. Beginning with a section exploring detailed methods for use of zebrafish to model a variety of human diseases, the book continues by illuminating the key ongoing role of the fish model in studies of the vertebrate nervous system, tools and approaches using zebrafish to study stem cell and regenerative biology, as well as techniques in genetics and genomics. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Zebrafish: Methods and Protocols, Third Edition serves as an invaluable guide to propel advances in developmental biology, disease modeling, and regeneration research using zebrafish and medaka as model systems.
The Zebrafish In Biomedical Research
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Author : Samuel Cartner
language : en
Publisher: Academic Press
Release Date : 2019-11-22
The Zebrafish In Biomedical Research written by Samuel Cartner and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-22 with Science categories.
The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research. Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications Includes the work of world-renowned authors Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series
Cancer And Zebrafish
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Author : David M. Langenau
language : en
Publisher: Springer
Release Date : 2016-05-10
Cancer And Zebrafish written by David M. Langenau and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-10 with Medical categories.
This volume focuses on defining the unique attributes of using the zebrafish cancer model for discovering important pathways and potential drug targets for the treatment of human cancers. Using the zebrafish model, the volume explores oncogene and tumor suppressor discovery, chemical genetic approaches, genomics, epigenetics, cancer imaging, and cell transplantation. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish cancer models, including T cell leukemia, rhabdomyosarcoma, liver and pancreatic cancer, melanoma, neuroblastoma, germ cell tumors, and malignant peripheral sheath tumors. A chapter is also dedicated to the development and utilization of other piscine models of cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and cancer, providing a much needed resource on the powerful attributes of the zebrafish model system.
The Zebrafish Disease Models And Chemical Screens
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Author :
language : en
Publisher: Academic Press
Release Date : 2011-09-09
The Zebrafish Disease Models And Chemical Screens written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-09 with Technology & Engineering categories.
This volume of Methods in Cell Biology is the 3e, and provides comprehensive compendia of laboratory protocols and reviews covering all the new methods developed since 2004. This new volume on Disease Models and Chemical Screens, covers two rapidly emerging and compelling applications of the zebrafish. Details state-of-the art zebrafish protocols, delineating critical steps in the procedures as well as potential pitfalls This volume concentrates on Disease Models and Chemical Screens
Animal Models Of Human Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2011-03-04
Animal Models Of Human Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-04 with Science categories.
Animal experiments have contributed much to our understanding of mechanisms of disease and are important for determining new therapies. This volume reviews the latest research and developments in this field. * Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields