Zebrafish Neurobehavioral Protocols


Zebrafish Neurobehavioral Protocols
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Zebrafish Neurobehavioral Protocols


Zebrafish Neurobehavioral Protocols
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Author : Allan V. Kalueff
language : en
Publisher: Humana Press
Release Date : 2011-04-06

Zebrafish Neurobehavioral Protocols written by Allan V. Kalueff and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-06 with Medical categories.


As a model organism, zebrafish (Danio rerio) offer an opportunity to perform steadfast scientific investigations in a robust and high-throughput manner. In Zebrafish Neurobehavioral Protocols, experts in the field provide a series of detailed behavioral protocols dealing with the major current research areas in the field of behavioral neuroscience. The chapters discuss the use and interpretation of video-aided quantification of zebrafish behaviors, describe novel assays commonly used to quantify emotionality, learning, memory, and social behaviors in zebrafish, and instruct how to quantify endocrine responses and correlate them with behavior. Written in the Neuromethods series format, the chapters provide authoritative reviews of many commonly used approaches in the field today. This "how to" book will be a useful practical guide for zebrafish researchers and will complement another related book from this series, Zebrafish Models in Neurobehavioral Research. Cutting-edge and timely, Zebrafish Neurobehavioral Protocols serves as an excellent compilation epitomizing the growing potential of zebrafish in modern scientific inquiry.



Zebrafish Protocols For Neurobehavioral Research


Zebrafish Protocols For Neurobehavioral Research
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Author : Allan V. Kalueff
language : en
Publisher: Humana Press
Release Date : 2012-06-06

Zebrafish Protocols For Neurobehavioral Research written by Allan V. Kalueff and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-06 with Medical categories.


Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research. Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders. Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe.



Zebrafish Models In Neurobehavioral Research


Zebrafish Models In Neurobehavioral Research
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Author : Allan V. Kalueff
language : en
Publisher: Humana Press
Release Date : 2010-10-28

Zebrafish Models In Neurobehavioral Research written by Allan V. Kalueff and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-28 with Medical categories.


Animal models have traditionally played a crucial role in improving our understanding of brain pathogenesis. Zebrafish (Danio rerio) have generated considerable discoveries in the areas of genetics, embryology, endocrinology, and neuroscience. Zebrafish Models in Neurobehavioral Research emphasizes the growing importance of zebrafish in neurobehavioral research and portrays an extensive, thorough perspective on the emergence of zebrafish as robust and translational models. Written by leading international experts, the book covers major topics ranging from stress to learned recognition of environment, encompassing a wide spectrum of the utility of zebrafish within neurobiological disciplines. The chapters provide authoritative reviews of many zebrafish paradigms commonly used in the field today. This book will be a useful guide for zebrafish researchers, and will complement another related book from the popular Neuromethods series, Zebrafish Neurobehavioral Protocols. Comprehensive and up-to-date, Zebrafish Models in Neurobehavioral Research serves as an ideal resource for scientists new to the field as well as for established researchers seeking valuable insight into the growing utility of zebrafish in neuroscience.



Zebrafish Protocols For Neurobehavioral Research


Zebrafish Protocols For Neurobehavioral Research
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Author : Allan V. Kalueff
language : en
Publisher: Humana Press
Release Date : 2012-06-06

Zebrafish Protocols For Neurobehavioral Research written by Allan V. Kalueff and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-06 with Medical categories.


Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research. Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders. Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe.



Behavioral And Neural Genetics Of Zebrafish


Behavioral And Neural Genetics Of Zebrafish
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Author : Robert T. Gerlai
language : en
Publisher: Academic Press
Release Date : 2020-04-03

Behavioral And Neural Genetics Of Zebrafish written by Robert T. Gerlai and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-03 with Medical categories.


Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and current concepts pertinent to their neurobehavioral genetics. Discussing their natural behavior, motor function, learning and memory, this book focuses on the fry and adult zebrafish, featuring a comprehensive account of modern genetic and neural methods adapted to, or specifically developed for, Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish are presented, as is a section on bioinformatics and "big-data" related questions. Provides the most comprehensive snapshot of the fast-evolving zebrafish neurobehavior genetics field Describes behavioral, genetic and neural methods and concepts for use in adult and larval zebrafish Features examples of zebrafish models of human central nervous system disorders Discusses bioinformatics questions pertinent to zebrafish neurobehavioral genetics



The Rights And Wrongs Of Zebrafish Behavioral Phenotyping Of Zebrafish


The Rights And Wrongs Of Zebrafish Behavioral Phenotyping Of Zebrafish
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Author : Allan V. Kalueff
language : en
Publisher: Springer
Release Date : 2017-02-06

The Rights And Wrongs Of Zebrafish Behavioral Phenotyping Of Zebrafish written by Allan V. Kalueff and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-06 with Medical categories.


Animal models and tests have become increasingly important for biomedical research, enabling a better understanding of pathogenic pathways involved in various human disorders. Over the last decades, zebrafish (Danio rerio) have become a very popular model organism in biomedical research. Recently, this fish has entered the waters of neuroscience and biological psychiatry, quickly becoming an indispensable model species in this field. With a high genetic homology to humans (~75% based on coding regions), it is not surprising that humans and fish are very similar physiologically (and behaviorally). Therefore, it should not come as a surprise that zebrafish can be an excellent model of human neuropsychiatric disorders. While some classical psychiatrists may not too easily be persuaded by this generalization, the current book “The rights and wrongs of zebrafish: principles of behavioral phenotyping and CNS disease modeling” explains, in a domain-by-domain manner, how exactly zebrafish models can be used to target a wide range of human brain disorders and aberrant phenotypes. The contributors to this book are leading international scholars whose work spearheads innovative zebrafish neuroscience research around the world. Written by top experts in the field, this book makes for a useful, balanced and up-to-date reading that outlines the use of zebrafish to study the pathological mechanisms underlying neuropsychiatric disorders.



Biology Of Stress In Fish


Biology Of Stress In Fish
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Author : Carl B. Schreck
language : en
Publisher: Academic Press
Release Date : 2016-11-01

Biology Of Stress In Fish written by Carl B. Schreck and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-01 with Technology & Engineering categories.


Biology of Stress in Fish: Fish Physiology provides a general understanding on the topic of stress biology, including most of the recent advances in the field. The book starts with a general discussion of stress, providing answers to issues such as its definition, the nature of the physiological stress response, and the factors that affect the stress response. It also considers the biotic and abiotic factors that cause variation in the stress response, how the stress response is generated and controlled, its effect on physiological and organismic function and performance, and applied assessment of stress, animal welfare, and stress as related to model species. Provides the definitive reference on stress in fish as written by world-renowned experts in the field Includes the most recent advances and up-to-date thinking about the causes of stress in fish, their implications, and how to minimize the negative effects Considers the biotic and abiotic factors that cause variation in the stress response



Animal Models For The Study Of Human Disease


Animal Models For The Study Of Human Disease
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Author : Angela L. Shamchuk
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-29

Animal Models For The Study Of Human Disease written by Angela L. Shamchuk and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-29 with Medical categories.


Olfactory dysfunction, although caused by many factors including physical damage and genetic abnormalities, is an early stage symptom of several neurodegenerative diseases. Not only is the olfactory system subject to the specific histological abnormalities but patients also lose the capacities to detect, identify, and discriminate among odors. In addition to olfactory deficits, motor dysfunction is another prominent manifestation of these conditions. Recent studies have begun to create zebrafish (Danio rerio) models for neurodegenerative diseases. Despite successful execution, there remains a great deal of potential in testing the models using established methods of olfactory and motion assessment. This chapter discusses the current zebrafish models and suggests olfactory and motor endpoints for Parkinson's, Alzheimer's, Huntington's, multiple system atrophy, and amyotrophic lateral sclerosis.



Animal Models For The Study Of Human Disease


Animal Models For The Study Of Human Disease
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Author : P. Michael Conn
language : en
Publisher: Academic Press
Release Date : 2017-06-20

Animal Models For The Study Of Human Disease written by P. Michael Conn and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-20 with Medical categories.


Animal Models for the Study of Human Disease, Second Edition, provides needed information on model sharing, animal alternatives, animal ethics and access to databanks of models, bringing together common descriptions of models for busy researchers across biomedical and biological sciences. Offering easily searchable advantages and disadvantages for each animal model and organized by disease topics, this resource aids researchers in finding the best animal model for research in human disease. Organized by disease orientation for ease of searchability Provides information on locating resources, animal alternatives, and animal ethics Covers a broad range of animal models used in research for human disease Contributed by leading experts across the globe Expanded coverage of diabetes and neurological diseases



Olfaction In Animal Behaviour And Welfare


Olfaction In Animal Behaviour And Welfare
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Author : Birte L Nielsen
language : en
Publisher: CABI
Release Date : 2017-06-29

Olfaction In Animal Behaviour And Welfare written by Birte L Nielsen and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-29 with Medical categories.


Evidence-based, yet entirely practical, this important new text builds upon the basics of neuroscience to describe the links between olfaction and animal behaviour, and the effects of odours in animal welfare. Animals use smells in a multitude of ways: to orientate themselves, to create social bonds, to recognise food, to initiate reproduction, and to avoid predators and imminent threats such as fire. Starting from the scientific basis of olfaction and odour perception, the book covers pheromones and behavioural tests, before describing the role of olfaction in feeding behaviour, reproduction, disease detection, and animal housing. This is a captivating introduction to the world of smells, suitable for advanced students, researchers, and teachers of applied ethology, animal welfare and veterinary science.