Essentials Of Cancer Genomic Computational Approaches And Precision Medicine
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Essentials Of Cancer Genomic Computational Approaches And Precision Medicine
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Author : Nosheen Masood
language : en
Publisher: Springer Nature
Release Date : 2020-03-20
Essentials Of Cancer Genomic Computational Approaches And Precision Medicine written by Nosheen Masood and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-20 with Medical categories.
This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology in cancer research. Lastly, the book discusses current and potential future applications of pharmacogenomics in clinical cancer therapy and cancer drug development.
Essentials Of Cancer Genomic Computational Approaches And Precision Medicine
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Author :
language : en
Publisher:
Release Date : 2020
Essentials Of Cancer Genomic Computational Approaches And Precision Medicine written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Cancer categories.
This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology in cancer research. Lastly, the book discusses current and potential future applications of pharmacogenomics in clinical cancer therapy and cancer drug development.
Advancing Healthcare Through Personalized Medicine
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Author : Priya Hays
language : en
Publisher: Springer Nature
Release Date : 2021-09-27
Advancing Healthcare Through Personalized Medicine written by Priya Hays and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-27 with Medical categories.
This book provides a unique perspective on the biomedical and societal implications of personalized medicine and how it helps to mitigate the healthcare crisis and rein in ever-growing expenditure. It introduces the reader to the underlying concepts at the heart of personalized medicine. An innovative second edition, this book functions as an update to the successful first edition to include new, state-of-the-art information and advancements in the fast-paced field of personalized medicine. Chapters examine pharmacogenomics, targeted therapies, individualized diagnosis and treatment, and cancer immunotherapies. The book also features an essential discussion on how the advent of genomic technologies gives clinicians the capability to predict and diagnose disease more efficiently and offers a detailed up-to-date compilation of clinical trials in cancer leading to breakthrough therapies. The book also addresses the impact of Big Data on personalized medicine and the newfound applications of digital health and artificial intelligence. A work that advocates for a patient-centered approach, Advancing Healthcare Through Personalized Medicine, Second Edition is an invaluable text for clinicians, healthcare providers, and patients.
Breast Cancer From Bench To Personalized Medicine
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Author : Saima Shakil Malik
language : en
Publisher: Springer Nature
Release Date : 2022-05-14
Breast Cancer From Bench To Personalized Medicine written by Saima Shakil Malik and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-14 with Medical categories.
This book provides detailed information on the etiology, pathogenesis, diagnosis, prognosis, and treatment strategies for breast cancer. The first section of the book presents epidemiology, risk factors, histopathological, immunohistochemistry, and molecular subtypes of breast cancer based on the receptor status. It also discusses the association of breast cancer with other hormone-sensitive cancers. The second section of the book covers cover BRCA1 and BRCA2-associated breast carcinogenesis, early-stage progression of breast cancer, and noninvasive biomarkers for the early detection of breast cancer. It also discusses the role of epigenetic modifications and non-coding RNAs in breast cancer metastasis and explores these as the biomarkers and therapeutic targets for breast cancer therapy. Further, it discusses the role of fibrinolytic mechanisms and circulating tumor cells in breast cancer diagnosis, prognosis, and treatment. The book also provides an update on oral poly(ADP-ribose) polymerase (PARP) inhibitors to treat breast cancer. Finally, it offers potential new options for personalized therapies for breast cancer patients, including optimizing drug dosage and identifying genetic changes associated with cancer symptom occurrence and severity.
Epidemiology Of Endocrine Tumors
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Author : Jahangir Moini
language : en
Publisher: Elsevier
Release Date : 2021-03-03
Epidemiology Of Endocrine Tumors written by Jahangir Moini and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-03 with Medical categories.
Epidemiology of Endocrine Tumors brings current data and clinical research into one source for a multidisciplinary audience. The book discusses the prevalence, incidence, etiology, pathology, diagnosis and treatment of various endocrine tumors. With clear and focused writing, it is essential reading for healthcare professionals, endocrinologists, oncologists, and public health professionals. Users will be able to bridge the knowledge gap that exists in the comprehensive coverage surrounding the epidemiology of endocrine tumors. Globally, the prevalence and incidence of endocrine tumors is high. This audience needs a treatise where they can gain a broad overview of endocrine tumors with a focus on epidemiology. - Supplies information about the epidemiology of various endocrine tumors, both benign and malignant, to endocrinologists, oncologists and related health care professionals - Focuses on the impact upon costs and patient deaths due to complications of these tumors - Describes how endocrine tumors affect various age groups and ethnicities, discussing the prevention of endocrine tumors - Presents chapters on Cancer Problem, Specific Endocrine Tumors, Prevention, Detection and Diagnosis, and Treatment of Endocrine Tumors - Provides review questions with an answer key and detailed glossary
Drugs And A Methodological Compendium
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Author : Vikrant Singh Rajput
language : en
Publisher: Springer Nature
Release Date : 2023-09-23
Drugs And A Methodological Compendium written by Vikrant Singh Rajput and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-23 with Science categories.
This book provides a meticulous view on methodological drug discovery and development insights from bench to bedside. The current book threads almost each step encompassing drug the discovery and development of a molecule. The chapters focus on computational modus operandi, pharmacological optimization approaches, modern high-throughput screening methods and in-vitro procedures, role of structural biologists in drug discovery and development, medicinal chemistry approaches for drug design, formulation and drug delivery, in-vivo evaluations of candidate molecules, clinical trial procedures and others. The book also covers specific case studies, regulatory approval proceedings, and industrial view point alongside the aforementioned conceptual layout. And at the same time, the volume integrates medical, biological, medicinal, pharmacological and computational streams, and it is suggested as an ideal guideline to a wide audience including molecular biologists, biochemist, pharmacologists, medicinal chemist, toxicologists, drug discovery and development researchers, and all other students interested in these disciplines.
Plant Based Foods And Their Implications In Brain Health
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Author : Soumya Mukherjee
language : en
Publisher: CRC Press
Release Date : 2024-12-23
Plant Based Foods And Their Implications In Brain Health written by Soumya Mukherjee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-23 with Science categories.
Phytoconstituents are a valuable source of new lead compounds due to their structural variety. The accelerated rate of human ageing brought about by the 21st century's longer life expectancy seems to be one of the major problems facing varied cultures worldwide. Ageing and the onset of chronic diseases appear to be significantly influenced by the type of food consumption pattern that people follow throughout their lives. There is strong evidence that Mediterranean diets are linked to a lower risk of brain disorders. A greater proportion of rural communities in the Mediterranean basin eat a diet high in plant-based foods daily. Stressors like reactive oxygen and reactive nitrogen species have a major negative influence on the brain in addition to the cardiovascular system. Foods, particularly those derived from plants, are a great source of vitamins, antioxidants, polyphenols, and vital fatty acids, according to a growing body of epidemiological research. Studies indicate the effect of antioxidant vitamins on brain health, including ascorbic acid and α-tocopherol. Polyphenols and other plant-derived bioactivities influence how animal and human brains operate by reducing the amount of oxidative stress and controlling different signal transduction pathways, according to a large body of experimental evidence. The present volume provides a collation of recent developments in the field with special reference to various types of plant-based phytoconstituents. The book's content is relevant and interesting to a wide range of audiences from the backgrounds of plant sciences, pharmacy, biochemistry, and molecular biology. Apart from being a good reference material source, the book is relevant to plant biotechnologists and students/researchers in the field.
Biotechnology Of Terpenoid Production From Microbial Cell Factories
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Author : Pratima Gupta
language : en
Publisher: Academic Press
Release Date : 2021-04-17
Biotechnology Of Terpenoid Production From Microbial Cell Factories written by Pratima Gupta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-17 with Technology & Engineering categories.
Biotechnology of Terpenoid Production from Microbial Cell Factories is a unique reference to help researchers, scientists and scholars explore available strategies involved in the production of terpenoid-based, value-added compounds from GRAS status (Generally Recognized as Safe by FDA) microbes to address the associated challenges for the industry. The book covers the most up-to-date information about microbial terpenoid production, including culture condition modulation for the improved and high-specificity production of terpenoid and their in-situ extraction. Each class of terpenoid is explained in detail, including their nutritional and pharmaceutical information and their molecular aspects. - Provides an in-depth look at both the natural and metabolic engineering aspects of microbial terpenoid production - Includes production strategies and existing challenges for each class of terpenoid from microbial sources - Presents broad application opportunities of terpenoids such as food additives, pharmaceuticals and fragrances - Includes brief chapter summaries and a glossary for each chapter to simplify technical applications
Clinical Precision Medicine
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Author : Judy S. Crabtree
language : en
Publisher: Academic Press
Release Date : 2019-11-15
Clinical Precision Medicine written by Judy S. Crabtree and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-15 with Medical categories.
Clinical Precision Medicine: A Primer offers clinicians, researchers and students a practical, up-to-date resource on precision medicine, its evolving technologies, and pathways towards clinical implementation. Early chapters address the fundamentals of molecular biology and gene regulation as they relate to precision medicine, as well as the foundations of heredity and epigenetics. Oncology, an early adopter of precision approaches, is considered with its relationship to genetic variation in drug metabolism, along with tumor immunology and the impact of DNA variation in clinical care. Contributions by Stephanie Kramer, a Clinical Genetic Counselor, also provide current information on prenatal diagnostics and adult genetics that highlight the critical role of genetic counselors in the era of precision medicine. - Includes applied discussions of chromosomes and chromosomal abnormalities, molecular genetics, epigenetic regulation, heredity, clinical genetics, pharmacogenomics and immunogenomics - Features chapter contributions from leaders in the field - Consolidates fundamental concepts and current practices of precision medicine in one convenient resource
Bioinformatics And Human Genomics Research
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Author : Diego A. Forero
language : en
Publisher: CRC Press
Release Date : 2021-12-22
Bioinformatics And Human Genomics Research written by Diego A. Forero and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-22 with Science categories.
Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in human and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide expression studies and genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.