Inside Out Vs Outside In Paradigms In Multiple Sclerosis Etiopathogenesis
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Inside Out Vs Outside In Paradigms In Multiple Sclerosis Etiopathogenesis
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Author : Antonio Luchicchi
language : en
Publisher: Frontiers Media SA
Release Date : 2021-04-12
Inside Out Vs Outside In Paradigms In Multiple Sclerosis Etiopathogenesis written by Antonio Luchicchi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-12 with Science categories.
Topic Editor Paolo Preziosa received speaker honoraria from Biogen Idec, Novartis, Merck Serono and ExceMED. The rest of Topic Editors declare no competing interests with regards to the Research Topic.
Clinical Aspects Of Multiple Sclerosis Essentials And Current Updates
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Author : Shitiz Sriwastava
language : en
Publisher: Elsevier
Release Date : 2024-01-13
Clinical Aspects Of Multiple Sclerosis Essentials And Current Updates written by Shitiz Sriwastava and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-13 with Medical categories.
Multiple Sclerosis (MS) is an inflammatory autoimmune disease affecting the brain and spinal cord. Despite significant advances in treatment modalities the prognosis of this patient population is still poor. New Updates on Clinical Aspects of Multiple Sclerosis reviews the clinical guidelines for diagnosis and treatment management for both pediatric and adult patients with Multiple sclerosis (MS). Multiple chapters present the various subtypes of MS in a case-based format, providing readers with the presentation of differential diagnosis. This book will also review the advancements in methods of assessing demyelinating plaques including, 7T MRI, DTI, PET, and MR spectroscopy. Multi-contributed, this book will become the essential guide for anyone in the field of MS Explores the practical applications of optical coherence tomography (OCT) and OCT angiography (OCTA) in assessing MS. Delves into utilizing advanced imaging modalities and corresponding radiological findings for the diagnosis and monitoring. Includes cutting-edge technologies: 7 Tesla (7T) magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), positron emission tomography (PET), and magnetic resonance spectroscopy (MR spectroscopy).
Damage Associated Molecular Patterns In Human Diseases
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Author : Walter Gottlieb Land
language : en
Publisher: Springer Nature
Release Date : 2023-03-10
Damage Associated Molecular Patterns In Human Diseases written by Walter Gottlieb Land and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-10 with Medical categories.
The core of this three-volume book deals with damage-associated molecular patterns abbreviated “DAMPs”, which are unique molecules that save life and fight for survival of all organisms on this planet by triggering robust inflammatory/immune defense responses upon any injury, including those caused by pathogens such as viruses and bacteria. However, these molecules also have a dark side: when produced in excess upon severe insults, they can trigger serious human diseases. The three volumes present current understanding of the importance of DAMP-promoted immune responses in the etiopathogenesis of human diseases and explore how this understanding is impacting diagnosis, prognosis, and future treatment. This third volume addresses the potential of DAMPs in clinical practice, as therapeutic targets and therapeutics, by focusing on a description of antigen-related diseases, which are pathogenetically dominated by DAMPs, that is, infectious and autoimmune disorders and allograft rejection (as an undesired function of these molecules), as well as tumor rejection (as the desired function of these molecules). The book is written for professionals from all medical and paramedical disciplines who are interested in the introduction of innovative data from modern inflammation and immunity research into clinical practice. In this sense, the book reflects an approach to translational medicine. The readership will include all practitioners and clinicians, in particular, ICU clinicians, infectiologists, microbiologists, virologists, hematologists, rheumatologists, diabetologists, neurologists, transplantologists, oncologists, and pharmacists. Also available: Damage-Associated Molecular Patterns in Human Diseases - Vol. 1: Injury-Induced Innate Immune Responses; Damage-Associated Molecular Patterns in Human Diseases - Vol. 2: Danger Signals as Diagnostics, Prognostics, and Therapeutic Targets.
Clinical Molecular And Adverse Responses To B Cell Therapies In Autoimmune Disease
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Author : Mohammed Yousuf Karim
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-03
Clinical Molecular And Adverse Responses To B Cell Therapies In Autoimmune Disease written by Mohammed Yousuf Karim and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-03 with Medical categories.
Multiple Sclerosis
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2001-08-10
Multiple Sclerosis written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-08-10 with Medical categories.
Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.
Automated Reasoning For Systems Biology And Medicine
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Author : Pietro Liò
language : en
Publisher: Springer
Release Date : 2019-06-11
Automated Reasoning For Systems Biology And Medicine written by Pietro Liò and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-11 with Computers categories.
This book presents outstanding contributions in an exciting, new and multidisciplinary research area: the application of formal, automated reasoning techniques to analyse complex models in systems biology and systems medicine. Automated reasoning is a field of computer science devoted to the development of algorithms that yield trustworthy answers, providing a basis of sound logical reasoning. For example, in the semiconductor industry formal verification is instrumental to ensuring that chip designs are free of defects (or “bugs”). Over the past 15 years, systems biology and systems medicine have been introduced in an attempt to understand the enormous complexity of life from a computational point of view. This has generated a wealth of new knowledge in the form of computational models, whose staggering complexity makes manual analysis methods infeasible. Sound, trusted, and automated means of analysing the models are thus required in order to be able to trust their conclusions. Above all, this is crucial to engineering safe biomedical devices and to reducing our reliance on wet-lab experiments and clinical trials, which will in turn produce lower economic and societal costs. Some examples of the questions addressed here include: Can we automatically adjust medications for patients with multiple chronic conditions? Can we verify that an artificial pancreas system delivers insulin in a way that ensures Type 1 diabetic patients never suffer from hyperglycaemia or hypoglycaemia? And lastly, can we predict what kind of mutations a cancer cell is likely to undergo? This book brings together leading researchers from a number of highly interdisciplinary areas, including: · Parameter inference from time series · Model selection · Network structure identification · Machine learning · Systems medicine · Hypothesis generation from experimental data · Systems biology, systems medicine, and digital pathology · Verification of biomedical devices “This book presents a comprehensive spectrum of model-focused analysis techniques for biological systems ...an essential resource for tracking the developments of a fast moving field that promises to revolutionize biology and medicine by the automated analysis of models and data.”Prof Luca Cardelli FRS, University of Oxford
Scleroderma
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Author : John Varga
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-12-21
Scleroderma written by John Varga and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-21 with Medical categories.
This essential book examines the most up-to-date information on scleroderma, offering a clear and concise synthesis of current concepts in pathogenesis and modern approaches to management. Presents a multidisciplinary approach to scleroderma care.
Textbook Of Neural Repair And Rehabilitation
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Author : Michael Selzer
language : en
Publisher: Cambridge University Press
Release Date : 2014-04-24
Textbook Of Neural Repair And Rehabilitation written by Michael Selzer and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-24 with Medical categories.
Volume 1 of the Textbook of Neural Repair and Rehabilitation covers the basic sciences relevant to recovery of function following injury to the nervous system.
The Neurology Of Religion
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Author : Alasdair Coles
language : en
Publisher: Cambridge University Press
Release Date : 2019-11-07
The Neurology Of Religion written by Alasdair Coles and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-07 with Medical categories.
Examines what can be learnt about the brain mechanisms underlying religious practice from studying people with neurological disorders.
Tuberculosis Of The Central Nervous System
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Author : Mehmet Turgut
language : en
Publisher: Springer
Release Date : 2017-06-13
Tuberculosis Of The Central Nervous System written by Mehmet Turgut and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-13 with Medical categories.
Written and edited by leading international authorities in the field, this book provides an in-depth review of knowledge of tuberculosis of the central nervous system, with emphasis on clinical, diagnostics, and therapeutic features. Tuberculosis, one of the most lethal diseases in human history, still poses a serious threat in the world together with economic and social problems, although a great progress in the fight against this infectious disease in the last century. It covers the full range of tuberculosis of central nervous system and the chapters are organized into six sections: (1) the cranial; (2) the spinal; and (3) the peripheral portions of the nervous system; followed by (4) a section on the laboratory studies in tuberculosis; (5) a section on medical and surgical therapy; and (6) further insights into tuberculosis. This comprehensive reference book will be an ideal source for neurosurgeons, neurologists and specialists upon infectious diseases seeking both basic and more sophisticated information and surgical procedures relating to the complications associated with tuberculosis involving the spine, brain and peripheral nerves.