Neurodegenerative Diseases


Neurodegenerative Diseases
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Neurodegenerative Diseases


Neurodegenerative Diseases
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Author : M. Flint Beal
language : en
Publisher: Cambridge University Press
Release Date : 2005-06-02

Neurodegenerative Diseases written by M. Flint Beal and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-06-02 with Medical categories.


Neurodegenerative diseases are major contributors to disability and disease, with Alzheimer's and Parkinson's diseases the most prevalent. This major reference reviews the rapidly advancing knowledge of pathogenesis and treatment of neurodegenerative diseases in the context of a comprehensive survey of each disease and its clinical features. The editors and contributors are among the leading experts in the field internationally. Covering basic science, diagnostic tools and therapeutic approaches, the book focuses on all aspects of neurodegenerative disease, including the normal aging process. The dementias, prion diseases, Parkinson's disease and atypical parkinsonisms, neurodegenerative ataxias, motor neuron diseases, degenerative diseases with chorea, iron and copper disorders, and mitochondrial diseases, are all methodically presented and discussed, with extensive illustrations. In each case the underlying genetics, neuropathological and clinical issues are fully reviewed, making this the most complete as well as the most authoritative reference available to clinicians and neuroscientists.



Neurodegeneration


Neurodegeneration
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Author : Anthony Schapira
language : en
Publisher: John Wiley & Sons
Release Date : 2017-02-13

Neurodegeneration written by Anthony Schapira and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-13 with Medical categories.


This book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject. Presents a clinically oriented guide to the diseases caused by neurodegeneration Templated chapters combine clinical and research information on neurodegenerative diseases beginning with the common elements before treating each disease individually Diseases are grouped by anatomical regions of degeneration and include common disorders such as Parkinson’s Disease, Alzheimer’s Disease, Amyotrophic Lateral Sclerosis/Motor Neuron Disease, and Multiple Sclerosis as well as less common diseases Edited by globally leading authorities on the subject, and written by expert contributing authors



Neurodegenerative Diseases Biomarkers


Neurodegenerative Diseases Biomarkers
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Author : Philip V. Peplow
language : en
Publisher:
Release Date : 2021

Neurodegenerative Diseases Biomarkers written by Philip V. Peplow and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Biochemical markers categories.


This volume presents recent data on the latest achievements in new and emerging technologies for biomarkers and for innovations in their assessment. The chapters cover topics such as activation of microglia and macrophages in neurodegenerative diseases; oxidative stress and cellular dysfunction in neurodegenerative diseases; TSPO PET imaging as a biomarker of neuroinflammation in neurodegenerative disorders; and imaging biomarkers in Huntington's disease and amyotrophic lateral sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Neurodegenerative Diseases Biomarkers: Towards Translating Research to Clinical Practice is a valuable resource for both experimental and clinical experts in the field of neurodegenerative diseases who are looking to expand their knowledge of novel biomarkers in different types of neurodegenerative diseases.



Biometals In Neurodegenerative Diseases


Biometals In Neurodegenerative Diseases
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Author : Anthony R. White
language : en
Publisher: Academic Press
Release Date : 2017-04-28

Biometals In Neurodegenerative Diseases written by Anthony R. White and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-28 with Medical categories.


Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer’s Disease, Parkinson’s Disease, Motor Neuron Disease, Autism and lysosomal storage disorders. This book is written for academic researchers, clinicians and advanced graduate students studying or treating patients in neurodegeneration, neurochemistry, neurology and neurotoxicology. The scientific literature in this field is advancing rapidly, with approximately 300 publications per year adding to our knowledge of how biometals contribute to neurodegenerative diseases. Despite this rapid increase in our understanding of biometals in brain disease, the fields of biomedicine and neuroscience have often overlooked this information. The need to bring the research on biometals in neurodegeneration to the forefront of biomedical research is essential in order to understand neurodegenerative disease processes and develop effective therapeutics. Authoritative and timely resource bringing together the major findings in the field for those with an interest in metals and their role in the brain function, disease, and as therapeutic targets Written for academic researchers, clinicians and advanced graduate students studying, or treating, patients in neurodegeneration, neurochemistry, neurology and neurotoxicology Edited by international leaders in the field who have contributed greatly to the study of metals in neurodegenerative diseases



Neurodegenerative Diseases


Neurodegenerative Diseases
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Author : Jeffrey L. Cummings
language : en
Publisher: Oxford University Press
Release Date : 2016-11-14

Neurodegenerative Diseases written by Jeffrey L. Cummings and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-14 with Medical categories.


'Neurodegenerative Diseases' is the result of a conceptual revolution over the last decade in our understanding of neurodegenerative diseases as sharing unifying features. There is an increasing appreciation of the common biological and pathological features across seemingly varied neurodegenerative diseases that entail protein misfolding dysfunction and its consequences over time. Providing an overview of this conceptual change is the main theme for this work.



Pathogenesis Of Neurodegenerative Disorders


Pathogenesis Of Neurodegenerative Disorders
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Author : Mark P. Mattson
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-06-01

Pathogenesis Of Neurodegenerative Disorders written by Mark P. Mattson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-06-01 with Medical categories.


As the average life expectancy of many populations throughout the world increases, so to does the incidence of such age-related neurodegenerative disorders as Alzheimer's, Parkinson's, and Huntington's diseases. Rapid advances in our understanding of the molecular genetics and environmental factors that either cause or increase risk for age-related neurodegenerative disor ders have been made in the past decade. The ability to evaluate, at the cellular and molecular level, abnormalities in postmortem brain tissue from patients, when taken together with the development of valuable animal and cell-culture models of neurodegenerative disorders has allowed the identification of sequences of events within neurons that result in their demise in specific neurodegenerative disorders. Though the genetic and environmental factors that pro mote neurodegeneration may differ among disorders, shared biochemical cascades that will ultimately lead to the death of neurons have been identified. These cascades involve oxyradical production, aberrant regulation of cellular ion homeostasis and activation of a stereotyped sequence of events involving mitochondrial dysfunction and activa tion of specific proteases. Pathogenesis of Neurodegenerative Disorders provides a timely compilation of articles that encompasses fundamental mechanisms involved in neurodegenerative disorders. In addition, mechanisms that may prevent age-related neurodegenerative disorders are presented. Each chapter is written by an expert in the particular neurodegenerative disorder or mechanism or neuronal death discussed.



Neurodegenerative Diseases


Neurodegenerative Diseases
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Author : Jagan A Pillai PhD
language : en
Publisher: Oxford University Press
Release Date : 2016-10-17

Neurodegenerative Diseases written by Jagan A Pillai PhD and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-17 with Medical categories.


As the global population ages the impact of neurodegenerative diseases like Alzheimer's disease and Parkinson's disease are significant forces in shaping human health and quality of life in the 21st century. Insights into understanding these diseases, and knowing how to treat them are major frontiers of scientific research. Neurodegenerative Diseases: Unifying Principles is the result of a conceptual revolution over the last decade in our understanding of neurodegenerative diseases as sharing unifying features. There is an increasing appreciation of the common biological and pathological features across seemingly varied neurodegenerative diseases that entail protein misfolding dysfunction and its consequences over time. Providing an overview of this conceptual change is the main theme for the book. Conventional approach emphasize the differences among neurodegenerative disorders, here Drs. Cummings and Pillai compile the increasingly compelling evidence that these disorders share many features and that insights in one may be rapidly translated into advances in another. The goal is to accelerate understanding by showing linkages among biological, pathological, can clinical aspects of this class of diseases. This collection of 19, inter-related chapters, articulates and broadens our view of the unifying features that initiate and drive disease progression across a variety of neurodegenerative diseases over time. This book will serve as an outstanding sourcebook of insights from experts that have played key roles in this story.



Pathology Prevention And Therapeutics Of Neurodegenerative Disease


Pathology Prevention And Therapeutics Of Neurodegenerative Disease
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Author : Sarika Singh
language : en
Publisher: Springer
Release Date : 2018-09-24

Pathology Prevention And Therapeutics Of Neurodegenerative Disease written by Sarika Singh and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-24 with Medical categories.


This book, written by a leading panel of experts in the field of neurosciences, provides a comprehensive overview of the pathology of neurodegenerative diseases as well as the preventive measures. Prevention is important due to the lack of early diagnostic markers and the limitations/ problems of treating neurodegenerative diseases



Neuropathology Of Neurodegenerative Diseases Book And Online


Neuropathology Of Neurodegenerative Diseases Book And Online
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Author : Gabor G. Kovacs
language : en
Publisher: Cambridge University Press
Release Date : 2014-12-04

Neuropathology Of Neurodegenerative Diseases Book And Online written by Gabor G. Kovacs and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-04 with Medical categories.


This heavily illustrated, must-have practical guide aids medical specialists and trainees in the diagnosis of neurodegenerative diseases. Includes diagnostic algorithms.



The Molecular And Clinical Pathology Of Neurodegenerative Disease


The Molecular And Clinical Pathology Of Neurodegenerative Disease
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Author : Patrick A. Lewis
language : en
Publisher: Academic Press
Release Date : 2018-11-16

The Molecular And Clinical Pathology Of Neurodegenerative Disease written by Patrick A. Lewis and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-16 with Science categories.


The Molecular and Clinical Pathology of Neurodegenerative Disease brings together in one volume our current understanding of the molecular basis of neurodegeneration in humans, targeted at neuroscientists and graduate students in neuroscience, and the biomedical and biological sciences. Bringing together up-to-date molecular biology data with clinical evidence, this book sheds a light on common molecular mechanisms that underlie many different neurodegenerative diseases and addresses the molecular pathologies in each. The combined research and clinical background of the authors provides a unique perspective in relating clinical experiences with the molecular understanding needed to examine these diseases and is a must-read for anyone who wants to learn more about neurodegeneration. Provides an up-to-date summary of neurodegeneration at a molecular, cellular, and tissue level for the most common human disorders Describes the clinical background and underlying molecular processes for Alzheimer’s disease, Parkinson’s, Prion, Motor Neuron, Huntington’s, and Multiple Sclerosis Highlights the state-of-the-art treatment options for each disorder Details examples of relevant cutting edge experimental systems, including genome editing and human pluripotent stem cell-derived neuronal models