10 Years Of Frontiers In Genetics Past Discoveries Current Challenges And Future Perspectives
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10 Years Of Frontiers In Genetics Past Discoveries Current Challenges And Future Perspectives
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Author : William C. Cho
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-02
10 Years Of Frontiers In Genetics Past Discoveries Current Challenges And Future Perspectives written by William C. Cho and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-02 with Science categories.
Genomic Advances And Challenges In Old And New World Camelids
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Author : Pamela Burger
language : en
Publisher: Frontiers Media SA
Release Date : 2020-09-11
Genomic Advances And Challenges In Old And New World Camelids written by Pamela Burger and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-11 with Science categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Genetically Engineered Crops
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2016-12-28
Genetically Engineered Crops written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-28 with Science categories.
Genetically engineered (GE) crops were first introduced commercially in the 1990s. After two decades of production, some groups and individuals remain critical of the technology based on their concerns about possible adverse effects on human health, the environment, and ethical considerations. At the same time, others are concerned that the technology is not reaching its potential to improve human health and the environment because of stringent regulations and reduced public funding to develop products offering more benefits to society. While the debate about these and other questions related to the genetic engineering techniques of the first 20 years goes on, emerging genetic-engineering technologies are adding new complexities to the conversation. Genetically Engineered Crops builds on previous related Academies reports published between 1987 and 2010 by undertaking a retrospective examination of the purported positive and adverse effects of GE crops and to anticipate what emerging genetic-engineering technologies hold for the future. This report indicates where there are uncertainties about the economic, agronomic, health, safety, or other impacts of GE crops and food, and makes recommendations to fill gaps in safety assessments, increase regulatory clarity, and improve innovations in and access to GE technology.
Precision Medicine Recent Advances Current Challenges And Future Perspectives
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Author : Oriana Awwad
language : en
Publisher: Frontiers Media SA
Release Date : 2024-06-18
Precision Medicine Recent Advances Current Challenges And Future Perspectives written by Oriana Awwad and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-18 with Science categories.
Personalized medicine (precision medicine) is an evolving field that comprises medical interventions tailored to individuals or groups of patients. It is designed to facilitate enhanced screening and earlier disease detection, more precise disease diagnosis, and improved treatment. Personalized medicine allows patients to receive specific therapies that work best for them aiming for more effective treatment, better outcomes, safer clinical managements and more efficient health systems.
Insights In Synthetic Biology 2021 Novel Developments Current Challenges And Future Perspectives
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Author : Jean Marie François
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-05
Insights In Synthetic Biology 2021 Novel Developments Current Challenges And Future Perspectives written by Jean Marie François and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-05 with Science categories.
Insights In Pediatric Neurology 2021
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Author : Hong Ni
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-30
Insights In Pediatric Neurology 2021 written by Hong Ni and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-30 with Medical categories.
Targeting Ion Channels For Drug Discovery Emerging Challenges For High Throughput Screening Technologies
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Author : Ciria Hernandez
language : en
Publisher: Frontiers Media SA
Release Date : 2024-06-07
Targeting Ion Channels For Drug Discovery Emerging Challenges For High Throughput Screening Technologies written by Ciria Hernandez and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-07 with Science categories.
Ligand and voltage-gated ion channels are highly regulated protein molecules that cross the cell membrane allowing ion flow from one side of the membrane to the other. They are ubiquitously expressed in human tissues and consist of one of the largest and best understood functional groups of proteins, with more than 400 members spanning nearly 1% of the human genome. They are involved in a variety of fundamental physiological processes, and their malfunction causes numerous diseases. In terms of the challenges faced in the effort to discover specific drugs in ancient and emerging diseases, ion channels are the third-largest class of target proteins after G-protein-coupled receptors (GPCRs) and kinases. 15% of small molecule drug targets have been reported to be voltage- or ligand-gated ion channels, resulting in approximately 150 new drug candidates in preclinical and clinical studies. Of the ion channel targeting drugs found on the market, these were identified more than a decade ago, and many of the current studies are at various stages of scientific approval. Overcoming these challenges has led the field of ion channel drug discovery to transform over the past 15 years through major advancements in genetic target detection, validation, structure-based drug design, and drug modeling of cell-based diseases.
Recent Advances In Understanding The Genetics Of Immunological Disorders
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Author : Che Kang Lim
language : en
Publisher: Frontiers Media SA
Release Date : 2024-12-13
Recent Advances In Understanding The Genetics Of Immunological Disorders written by Che Kang Lim and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-13 with Science categories.
Immunological disorders are diseases or conditions due to the dysfunction of the immune system. They include primary immunodeficiency syndromes, autoimmune diseases, asthma, allergy, and autoinflammatory syndromes. These disorders disrupt our body’s ability to defend against pathogens. In addition, it may lead to exaggerated chronic inflammatory responses and tissue damage. Immunological disorders are clinically and genetically heterogeneous. The phenotypic spectrum of the diseases is broad in some of the disorders. On the other hand, the clinical phenotype derived from distinct genotypes can overlap, and the same phenotype can be cross-shared in different disorders. Therefore, accurate diagnosis and effective management are challenging. Over the last decade, advances in genomics and sequencing platforms have accelerated the understanding of how candidate genes contribute to the development of immunological disorders. Significant progress has been made in discovering disease-causing genes for rare monogenic immunological disorders, especially in immunodeficiency syndrome. These findings shed insights into disease mechanisms and facilitated the identification of new biomarkers that can help in diagnosis, prognosis, and development of novel clinical therapeutic approaches.
Advances In Host Genetics And Microbiome In Colorectal Cancer Related Phenotypes
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Author :
language : en
Publisher: Elsevier
Release Date : 2024-10-11
Advances In Host Genetics And Microbiome In Colorectal Cancer Related Phenotypes written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-11 with Science categories.
Advances in Host Genetics and Microbiome in Colorectal Cancer-Related Phenotypes, Volume 112 in the Advances in Genetics series, highlights new advances in the field with this new volume presenting interesting chapters on topics such as What we need in colorectal cancer research, and why?, Host Genetics and Microbiota procedures in colorectal cancer research, Host Genetics-associated mechanisms in colorectal cancer, Microbiota-associated mechanisms in colorectal cancer, Inflammation regulation in colorectal cancer, Microbiota and detrimental protein metabolites in colorectal cancer, Microbiota and other detrimental metabolites in colorectal cancer, Microbiota and beneficial metabolites in colorectal cancer, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Advances in Genetics series - Includes the latest information on new advancements in the study of genetics
Computational Drug Discovery
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Author : Pooja A. Chawla
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2024-10-07
Computational Drug Discovery written by Pooja A. Chawla and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-07 with Science categories.
Computational methods and understanding computational models are important in modern drug discovery. The book focuses on computational approaches that can improve the development of in silico methodologies. It includes lead hit methods, docking algorithms, computational chiral compounds, structure-based drug design, GROMACS and NAMD, structural genomics, toxicity prediction, enzyme inhibitors and peptidomimetic therapeutics