A Differential Evolution Approach To Feature Selection In Genomic Prediction
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A Differential Evolution Approach To Feature Selection In Genomic Prediction
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Author : Ian Whalen
language : en
Publisher:
Release Date : 2018
A Differential Evolution Approach To Feature Selection In Genomic Prediction written by Ian Whalen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Electronic dissertations categories.
The use of genetic markers has become widespread for prediction of genetic merit in agricultural applications and is a beginning to show promise for estimating propensity to disease in human medicine. This process is known as genomic prediction and attempts to model the mapping between an organism's genotype and phenotype. In practice, this process presents a challenging problem. Sequencing and recording phenotypic traits are often expensive and time consuming. This leads to datasets often having many more features than samples. Common models for genomic prediction often fall victim to overfitting due to the curse of dimensionality. In this domain, only a fraction of the markers that are present significantly affect a particular trait. Models that fit to non-informative markers are in effect fitting to statistical noise, leading to a decrease in predictive performance. Therefore, feature selection is desirable to remove markers that do not appear to have a significant effect on the trait being predicted. The method presented here uses differential evolution based search for feature selection. This study will characterize differential evolution's efficacy in feature selection for genomic prediction and present several extensions to the base search algorithm in an attempt to apply domain knowledge to guide the search toward better solutions.
Evolution In Action Past Present And Future
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Author : Wolfgang Banzhaf
language : en
Publisher: Springer Nature
Release Date : 2020-07-08
Evolution In Action Past Present And Future written by Wolfgang Banzhaf and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-08 with Computers categories.
This edited research monograph brings together contributions from computer scientists, biologists, and engineers who are engaged with the study of evolution and how it may be applied to solve real-world problems. It also serves as a Festschrift dedicated to Erik D. Goodman, the founding director of the BEACON Center for the Study of Evolution in Action, a pioneering NSF Science and Technology Center headquartered at Michigan State University. The contributing authors are leading experts associated with the center, and they serve in top research and industrial establishments across the US and worldwide. Part I summarizes the history of the BEACON Center, with refreshingly personal chapters that describe Erik's working and leadership style, and others that discuss the development and successes of the center in the context of research funding, projects, and careers. The chapters in Part II deal with the evolution of genomes and evolvability. The contributions in Part III discuss the evolution of behavior and intelligence. Those in Part IV concentrate on the evolution of communities and collective dynamics. The chapters in Part V discuss selected evolutionary computing applications in domains such as arts and science, automated program repair, cybersecurity, mechatronics, and genomic prediction. Part VI deals with evolution in the classroom, using creativity in research, and responsible conduct in research training. The book concludes with a special chapter from Erik Goodman, a short biography that concentrates on his personal positive influences and experiences throughout his long career in academia and industry.
Genomic Intelligence
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Author : Sheetanshu Gupta
language : en
Publisher: CRC Press
Release Date : 2024-12-06
Genomic Intelligence written by Sheetanshu Gupta and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-06 with Science categories.
The field of metagenomics has revolutionized our comprehension of microbial diversity and function across various habitats, from the human body to terrestrial and aquatic environments. Simultaneously, advancements in AI have empowered researchers to analyze vast troves of genomic data with unprecedented speed and precision, facilitating new insights into the complex interplay between microorganisms and their surroundings. The subject matter in this book provides an overview of metagenomics and discusses the combination of metagenomics and AI and its significant consequences for advancements in science. The chapters examine the approaches, difficulties, and revolutionary uses of AI in metagenomics and provide insight into the convergence of genomics, metagenomics, and AI’s potential to revolutionize diverse fields from healthcare to environmental. Print edition not for sale in South Asia (India, Sri Lanka, Nepal, Bangladesh, Pakistan or Bhutan)
Machine Learning And Autonomous Systems
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Author : Joy Iong-Zong Chen
language : en
Publisher: Springer Nature
Release Date : 2022-02-10
Machine Learning And Autonomous Systems written by Joy Iong-Zong Chen and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-10 with Technology & Engineering categories.
This book involves a collection of selected papers presented at International Conference on Machine Learning and Autonomous Systems (ICMLAS 2021), held in Tamil Nadu, India, during 24–25 September 2021. It includes novel and innovative work from experts, practitioners, scientists and decision-makers from academia and industry. It covers selected papers in the area of emerging modern mobile robotic systems and intelligent information systems and autonomous systems in agriculture, health care, education, military and industries.
Computational Intelligence And Pattern Analysis In Biology Informatics
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Author : Ujjwal Maulik
language : en
Publisher: John Wiley & Sons
Release Date : 2011-03-21
Computational Intelligence And Pattern Analysis In Biology Informatics written by Ujjwal Maulik and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-21 with Medical categories.
An invaluable tool in Bioinformatics, this unique volume provides both theoretical and experimental results, and describes basic principles of computational intelligence and pattern analysis while deepening the reader's understanding of the ways in which these principles can be used for analyzing biological data in an efficient manner. This book synthesizes current research in the integration of computational intelligence and pattern analysis techniques, either individually or in a hybridized manner. The purpose is to analyze biological data and enable extraction of more meaningful information and insight from it. Biological data for analysis include sequence data, secondary and tertiary structure data, and microarray data. These data types are complex and advanced methods are required, including the use of domain-specific knowledge for reducing search space, dealing with uncertainty, partial truth and imprecision, efficient linear and/or sub-linear scalability, incremental approaches to knowledge discovery, and increased level and intelligence of interactivity with human experts and decision makers Chapters authored by leading researchers in CI in biology informatics. Covers highly relevant topics: rational drug design; analysis of microRNAs and their involvement in human diseases. Supplementary material included: program code and relevant data sets correspond to chapters.
Harnessing Ai And Machine Learning For Precision Wellness
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Author : Ghosh, Joyeta
language : en
Publisher: IGI Global
Release Date : 2025-03-05
Harnessing Ai And Machine Learning For Precision Wellness written by Ghosh, Joyeta and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-05 with Computers categories.
Advancements in artificial intelligence and machine learning are reshaping healthcare by enabling highly personalized wellness strategies tailored to individual needs. By analyzing vast datasets, including genetic, biometric, and lifestyle information, these technologies can predict disease risks, optimize treatment plans, and recommend proactive health interventions. Precision wellness moves beyond traditional healthcare models, offering dynamic, adaptive solutions that evolve with new scientific discoveries. This shift has the potential to reduce healthcare costs, alleviate the burden on medical systems, and improve overall health outcomes. However, ethical considerations, data privacy, and equitable access remain crucial challenges in realizing the full benefits of AI-driven healthcare. Harnessing AI and Machine Learning for Precision Wellness demystifies the complex world of AI and machine learning in healthcare, exploring how these technologies are being applied across various aspects of wellness. It delves into the mathematical foundations that underpin these technologies, examines real-world case studies, and discusses the ethical considerations that must guide their implementation. This book covers topics such as mathematics, mental health, and preventive care, and is a useful resource for medical and healthcare professionals, computer engineers, data scientists, psychologists, academicians, and researchers.
Machine Learning For Multimodal Healthcare Data
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Author : Andreas K. Maier
language : en
Publisher: Springer Nature
Release Date : 2023-11-25
Machine Learning For Multimodal Healthcare Data written by Andreas K. Maier and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-25 with Medical categories.
This book constitutes the proceedings of the First International Workshop on Machine Learning for Multimodal Healthcare Date, ML4MHD 2023, held in Honolulu, Hawaii, USA, in July 2023. The 18 full papers presented were carefully reviewed and selected from 30 submissions. The workshop's primary objective was to bring together experts from diverse fields such as medicine, pathology, biology, and machine learning. With the aim to present novel methods and solutions that address healthcare challenges, especially those that arise from the complexity and heterogeneity of patient data.
Genomic Prediction Of Complex Traits
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Author : Nourollah Ahmadi
language : en
Publisher: Springer Nature
Release Date : 2022-04-22
Genomic Prediction Of Complex Traits written by Nourollah Ahmadi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-22 with Science categories.
This volume explores the conceptual framework and the practical issues related to genomic prediction of complex traits in human medicine and in animal and plant breeding. The book is organized into five parts. Part One reminds molecular genetics approaches intending to predict phenotypic variations. Part Two presents the principles of genomic prediction of complex traits, and reviews factors that affect its reliability. Part Three describes genomic prediction methods, including machine-learning approaches, accounting for different degree of biological complexity, and reviews the associated computer-packages. Part Four reports on emerging trends such as phenomic prediction and incorporation into genomic prediction models of “omics” data and crop growth models. Part Five is dedicated to lessons learned from cases studies in the fields of human health and animal and plant breeding, and to methods for analysis of the economic effectiveness of genomic prediction. Written in the highly successful Methods in Molecular Biology series format, the book provides theoretical bases and practical guidelines for an informed decision making of practitioners and identifies pertinent routes for further methodological researches. Cutting-edge and thorough, Complex Trait Predictions: Methods and Protocols is a valuable resource for scientists and researchers who are interested in learning more about this important and developing field. Chapters 3, 9, 13, 14, and 21 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Data Science For Genomics
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Author : Amit Kumar Tyagi
language : en
Publisher: Academic Press
Release Date : 2022-11-27
Data Science For Genomics written by Amit Kumar Tyagi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-27 with Science categories.
Data Science for Genomics presents the foundational concepts of data science as they pertain to genomics, encompassing the process of inspecting, cleaning, transforming, and modeling data with the goal of discovering useful information, suggesting conclusions and supporting decision-making. Sections cover Data Science, Machine Learning, Deep Learning, data analysis, and visualization techniques. The authors then present the fundamentals of Genomics, Genetics, Transcriptomes and Proteomes as basic concepts of molecular biology, along with DNA and key features of the human genome, as well as the genomes of eukaryotes and prokaryotes. Techniques that are more specifically used for studying genomes are then described in the order in which they are used in a genome project, including methods for constructing genetic and physical maps. DNA sequencing methodology and the strategies used to assemble a contiguous genome sequence and methods for identifying genes in a genome sequence and determining the functions of those genes in the cell. Readers will learn how the information contained in the genome is released and made available to the cell, as well as methods centered on cloning and PCR. - Provides a detailed explanation of data science concepts, methods and algorithms, all reinforced by practical examples that are applied to genomics - Presents a roadmap of future trends suitable for innovative Data Science research and practice - Includes topics such as Blockchain technology for securing data at end user/server side - Presents real world case studies, open issues and challenges faced in Genomics, including future research directions and a separate chapter for Ethical Concerns
Soft Computing Methods For Genomic Analysis
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Author : Dr. Lohitha Lakshmi Kanchi and Dr. Lakshmi Praveena Tunuguntla
language : en
Publisher: Ashok Yakkaldevi
Release Date : 2023-03-11
Soft Computing Methods For Genomic Analysis written by Dr. Lohitha Lakshmi Kanchi and Dr. Lakshmi Praveena Tunuguntla and has been published by Ashok Yakkaldevi this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-11 with Art categories.
Among numerous cancers, breast cancer is one type of cancer in which most tumors are formed in females' breasts and rarely in males. Cell growth remains irregular in this type of cancer, and a cancerous tumor in the breast of women develops without a gap. The increasing occurrence of breast cancer in women typically leads to the death of females. Breast Cancer may be caused due to inherited DNA or abnormal change in DNA / RNA structure. The structure and arrangement of nucleotides in genomes decide the characteristics of living organisms. During the transition from parent to child via inheritance, certain abnormal changes in the arrangement of genes take place. The search for disease incidence and control procedures are being carried out quickly, despite considerable progress in breast cancer. It is determined that one reason for the origin and spread of breast cancer in subsequent generations is also genetic. Researchers concentrate on studying cancer cell gene sequences to detect instances of similarities and unusual changes in gene structure from parent to generation of children