A Holistic Approach To Organic Synthesis
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A Holistic Approach To Organic Synthesis
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Author : Philip Garner
language : en
Publisher: CRC Press
Release Date : 2024-02-23
A Holistic Approach To Organic Synthesis written by Philip Garner and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-23 with Medical categories.
Synthesis is one of the distinguishing features of chemistry as a science. It is the synthetic chemist who uses their intimate understanding of molecular structure and properties to produce materials of great value to society. Thus, it is important for students of chemistry to study synthesis and acquire a working knowledge that enables them to address the following question: given a specific molecular target, how does one formulate a plan for its synthesis? This synthesis primer provides students who have taken introductory organic chemistry with a set of tools that can be used to plan a synthesis. It may be used in conjunction with a synthetic methods course, or it can stand alone. Features: Provides students who have taken introductory organic chemistry with a set of tools that can be used to plan a synthesis Serves to help organic chemists at all levels to better understand published syntheses Focuses on natural products, their complexity, and diverse structures which challenge and inspire the chemists preparing them Succinct, readable treatment of important concepts and applications geared towards advanced undergraduates and graduate students Each synthesis covered begins with a brief discussion of the target molecule and challenges they present, followed by retrosynthetic considerations
Organic Synthesis
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Author : Stuart Warren
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-24
Organic Synthesis written by Stuart Warren and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-24 with Science categories.
One approach to organic synthesis is retrosynthetic analysis. With this approach a chemist will start with the structure of their target molecule and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. This “disconnection” approach to synthesis is now a fundamental part of every organic synthesis course. Organic Synthesis: The Disconnection Approach, 2nd Edition introduces this important technique, to help students to design their own organic syntheses. There are forty chapters: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. This second edition has been fully revised and updated with a modern look. Recent examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, “Organic Synthesis: Strategy and Control”. Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry. Organic Synthesis: The Disconnection Approach, 2nd edition provides a full course in retrosynthetic analysis for chemistry and biochemistry students and a refresher for organic chemists working in industry and academia.
Advanced Organic Chemistry I
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Author : Habtamu Abebe Agisho (PhD)
language : en
Publisher: JEC PUBLICATION
Release Date :
Advanced Organic Chemistry I written by Habtamu Abebe Agisho (PhD) and has been published by JEC PUBLICATION this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medical categories.
Welcome to "Advanced Organic Chemistry - I." This book is a culmination of my passion for organic chemistry and the recognition of the challenges students face in navigating the intricacies of this subject. As an author, my primary goal is to provide a resource that not only covers the essential principles but also instils a deep appreciation for the beauty and significance of advanced organic chemistry. In crafting this guide, I've drawn upon years of experience in teaching and research, aiming to strike a balance between theoretical concepts and practical applications. Each chapter is tailored to align with the as per curriculum, offering a structured approach to learning while encouraging critical thinking. The content is presented in a manner that I hope will demystify complex topics, making them more accessible and engaging for students. I would like to express my gratitude to my family for their meticulous efforts in refining the content, ensuring clarity, and maintaining a cohesive narrative. Additionally, I extend my appreciation to my institute for providing the necessary support and fostering an environment conducive to academic endeavours. It is my sincere hope that this book serves as a valuable companion for students undertaking organic chemistry sparking curiosity, facilitating a deeper understanding of organic chemistry, and ultimately contributing to a fulfilling academic journey.
Organic Synthesis
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Author : W A Smit
language : en
Publisher: Royal Society of Chemistry
Release Date : 2007-10-31
Organic Synthesis written by W A Smit and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-31 with Science categories.
The view of organic synthesis as "a concentrated expression of predictive ability and creative capacity" was advocated in the early 1950s. A concise and readable account of the role of synthesis in modern science, Organic Synthesis: The Science Behind the Art presents the general ideology of pursuits in the area of organic synthesis, and examines the methodologies that have evolved in the search for solutions to synthetic problems. This unique book details outstanding achievements of modern organic synthesis, not only for their scientific merits, but also for the aesthetic appeal of the target molecules chosen and the intrinsic beauty of the solutions to the problems posed. By judicious selection of data covering the main areas of synthetic explorations, this book serves to illustrate both the evolution of well-known approaches as well as recently emerged trends most likely to determine the future development of organic synthesis. Special attention is given to the consideration of principles of molecular design in promising and challenging areas of current research. Primarily aimed at advanced undergraduate and graduate students, Organic Synthesis: The Science Behind the Art will also be of interest to teachers, researchers and anyone requiring an introduction to the problems of organic synthesis.
Workbook For Organic Synthesis The Disconnection Approach
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Author : Stuart Warren
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-24
Workbook For Organic Synthesis The Disconnection Approach written by Stuart Warren and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-24 with Science categories.
One approach to organic synthesis is retrosynthetic analysis. With this approach chemists start with the structures of their target molecules and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. This “disconnection” approach to synthesis is now a fundamental part of every organic synthesis course. Workbook for Organic Synthesis: The Disconnection Approach, 2nd Edition This workbook provides a comprehensive graded set of problems to illustrate and develop the themes of each of the chapters in the textbook Organic Synthesis: The Disconnection Approach, 2nd Edition. Each problem is followed by a fully explained solution and discussion. The examples extend the student’s experience of the types of molecules being synthesised by organic chemists, and the strategies they employ to control their syntheses. By working through these examples students will develop their skills in analysing synthetic challenges, and build a toolkit of strategies for planning new syntheses. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. Together the workbook and textbook provide a complete course in retrosynthetic analysis. Organic Synthesis: The Disconnection Approach, 2nd Edition There are forty chapters in Organic Synthesis: The Disconnection Approach, 2nd Edition: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. In its second edition updated examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, Organic Synthesis: Strategy and Control. Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry. Workbook for Organic Synthesis: The Disconnection Approach, 2nd edition, combined with the main textbook, provides a full course in retrosynthetic analysis for chemistry and biochemistry students, and a refresher course for organic chemists working in industry and academia.
Strategies And Tactics In Organic Synthesis
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Author : Michael Harmata
language : en
Publisher: Academic Press
Release Date : 2012
Strategies And Tactics In Organic Synthesis written by Michael Harmata and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Chemistry, Organic categories.
A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, this book vividly demonstrates through first hand accounts how synthesis is really done and how by discovering new reactions, creating new designs and building molecules with atom and step economies, the advancement of the science of organic synthesis is providing solutions through function to create a better world. Presents state-of-the-art developments in organic synthesisProvides insight and offers new perspective to problem-solvingWritten by leading experts in the field.
Strategies And Tactics In Organic Synthesis
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Author : Michael Harmata
language : en
Publisher: Elsevier
Release Date : 2015-08-13
Strategies And Tactics In Organic Synthesis written by Michael Harmata and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-13 with Technology & Engineering categories.
Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, this classic provides stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project tell of the excitement of conception, the frustration of failure, and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project. This book series shows how synthesis is really done. Readers will be educated, challenged, and inspired by these accounts, which portray the idea that triumphs do not come without challenges. This innovative approach also helps illustrate how challenges to further advance the science and art of organic synthesis can be overcome, driving the field forward to meet the demands of society by discovering new reactions, creating new designs, and building molecules with atom and step economies that provide functional solutions to create a better world. Presents state-of-the-art developments in organic synthesis Provides insight and offers new perspective to problem-solving Written by leading experts in the field Uses firsthand narrative accounts to illustrate vividly the challenges and joys involved in advancing the science of organic synthesis
Strategies And Tactics In Organic Synthesis
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Author : Michael Harmata
language : en
Publisher:
Release Date : 2004
Strategies And Tactics In Organic Synthesis written by Michael Harmata and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Electronic books categories.
A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world. - Personal accounts of research in organic chemistry. - Written by internationally renowned scientists. - Details state of the art organic synthesis.
Total Synthesis Of Natural Products The Chiron Approach
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Author : Stephen Hanessian
language : en
Publisher: Pergamon
Release Date : 1983
Total Synthesis Of Natural Products The Chiron Approach written by Stephen Hanessian and has been published by Pergamon this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Science categories.
Green Techniques For Organic Synthesis And Medicinal Chemistry
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Author : Wei Zhang
language : en
Publisher: John Wiley & Sons
Release Date : 2012-07-23
Green Techniques For Organic Synthesis And Medicinal Chemistry written by Wei Zhang and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-23 with Medical categories.
Green chemistry is a new way of looking at organic synthesis and the design of drug molecules, offering important environmental and economic advantages over traditional synthetic processes. Pharmaceutical companies are increasingly turning to the principles of green chemistry in an effort to reduce waste, reduce costs and develop environmentally benign processes. Green Techniques for Organic Synthesis and Medicinal Chemistry presents an overview of the established and emerging techniques in green organic chemistry, highlighting their applications in medicinal chemistry. The book is divided into four parts: Introduction: Introduces the reader to the toxicology of organic chemicals,their environmental impact, and the concept of green chemistry. Green Catalysis: Covers a variety of green catalytic techniques including organocatalysis, supported catalysis, biocatalysis, fluorous catalysis, and catalytic direct C-H bond activation reactions. Green Synthetic Techniques: Presents a series of new techniques, assessing the green chemistry aspects and limitations (i.e. cost, equipment, expertise). Techniques include reactions in alternative solvents, atom economic multicomponent reactions, microwave and ultrasonic reactions, solid-supported synthesis, fluorous and ionic liquid-based recycling techniques, and flow reactors. Green Techniques in Pharmaceutical Industry: Covers applications of green chemistry concepts and special techniques for medicinal chemistry, including synthesis, analysis, separation, formulation, , and drug delivery. Process and business case studies are included to illustrate the applications in the pharmaceutical industry. Green Techniques for Organic Synthesis and Medicinal Chemistry is an essential resource on green chemistry technologies for academic researchers, R&D professionals and students working in organic chemistry and medicinal chemistry.