A Living History Of Immunology
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A Living History Of Immunology
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Author : Kendall Arthur Smith
language : en
Publisher: Frontiers Media SA
Release Date : 2015-11-04
A Living History Of Immunology written by Kendall Arthur Smith and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-04 with Electronic book categories.
In the highly competitive world of biomedical science, often the rush to publish and to be recognized as "first" with a new discovery, concept or method, is lost in the hurly-burly of the moment, as "the maddening crowd" moves on to the next "new thing". One of the great things about immunology today is that it has only become mature as a science within the last half-century, and especially within the past 35 years as a consequence of the revolution of molecular immunology, which has taken place only since 1980. Consequently, most of those who have contributed to our new understanding of how the immune system functions are still alive and well, and still contributing. Thus, "A Living History of Immunology" collates many stories from the investigators who actually performed the experiments that have established the frontiers of immunology. Accordingly, this volume combats "revisionist science", by those who want to alter history by telling the stories a different way than actually happened. In this regard, one of the good things about science vs. other disciplines is that we have the written record of what was done, when it was done and by whom. Even so, we do not have the complete story or narrative of how and why experiments were done, and what made the differences that led to success. This volume captures and chronicles some of these stories from the past fifty years in immunology.
A History Of Immunology
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Author : Arthur M. Silverstein
language : en
Publisher: Elsevier
Release Date : 2012-12-02
A History Of Immunology written by Arthur M. Silverstein and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.
This is a professional-level intellectual history of the development of immunology from about 1720 to about 1970. Beginning with the work and insights of the early immunologists in the 18th century, Silverstein traces the development of the major ideas which have formed immunology down to the maturation of the discipline in the decade following the Second World War. Emphasis is placed on the philosophic and sociologic climate of the scientific milieu in which immunology has developed, providing a background to the broad culture of the discipline. A professional-level intellectual history of the development of immunology from about 1720 to 1970, with emphasis placed on the social climate of the scientific milieu in which modern immunology evolved Written by an author very well known both as a historian of medical science and for his substantial research contributions to the immunopathology of the eye The only complete history of immunology available
Immunity
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Author : Alfred I. Tauber
language : en
Publisher: Oxford University Press
Release Date : 2017-01-02
Immunity written by Alfred I. Tauber and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-02 with Science categories.
Modern immunology traditionally conceives of the immune system as providing defense against pathogens. Alfred I. Tauber criticizes this conception of immunity as too narrow, because it discounts much of the immune system's other normal functions. These include active tolerance of nutritional exchanges with the environment and the stabilization of cooperative relationships with resident micro-organisms. An expanded account extends immunity's functional role from singular 'defense' to broadened discernment of environmental 'exchange.' This ecological perspective has profound theoretical implications, for the basic notion of immune identity is reconfigured: highlighting the organism as a holobiont (a consortium of diverse organisms living in cooperative relationships) challenges prevailing concepts of individuality and the self/nonself dichotomy heretofore organizing immune theory. Indeed, if theoretical interest is focused on the challenges of maintaining immune balance in the full ecological context of the organism, then immune regulation assumes new complexity. Tauber maintains that the key to unravelling that puzzle requires a critical re-assessment of the cognitive processes that underlie immune effector functions. Accordingly, he provides the outline of a re-formulated 'cognitive paradigm' that dispenses with agent-based models and adopts an ecologically conceived understanding of perception and information processing. The implications of this revised configuration of immunity and its deconstructed notions of individuality and selfhood have wide significance for philosophers and life scientists working in immunology, ecology, and the cognitive sciences.
History Of Immunology
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Author : Arthur M. Silverstein
language : en
Publisher:
Release Date : 1982
History Of Immunology written by Arthur M. Silverstein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with categories.
A History Of Medical Bacteriology And Immunology
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Author : W. D. Foster
language : en
Publisher: Butterworth-Heinemann
Release Date : 2014-05-20
A History Of Medical Bacteriology And Immunology written by W. D. Foster and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-20 with Medical categories.
A History of Medical Bacteriology and Immunology provides the account of the history of bacteriology from the year 1900 to 1938. This book presents details about the discovery of the important pathogenic bacteria of man, of how they were shown to be causally related to disease, and of the use of these discoveries in the diagnosis, treatment, and prevention of disease. Other topics discussed include the development of the germ theory of infectious diseases; contribution of Louis Pasteur and Robert Koch to medical bacteriology; and discovery of the more important human pathogenic bacteria. This text also discusses the scientific basis and practical application of immunology to medicine; main developments in bacteriology during the early 20th century; and chemotherapy of bacterial disease. This medically oriented text is beneficial for students and individuals conducting study on medical bacteriology and immunology.
A Historical Perspective On Evidence Based Immunology
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Author : Edward J. Moticka
language : en
Publisher: Newnes
Release Date : 2015-11-25
A Historical Perspective On Evidence Based Immunology written by Edward J. Moticka and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-25 with Medical categories.
A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology Presents concepts such as the division of lymphocytes into functionally different populations in their historical context Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells
A History Of Modern Immunology
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Author : Zoltan A. Nagy
language : en
Publisher: Academic Press
Release Date : 2013-10-11
A History Of Modern Immunology written by Zoltan A. Nagy and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-11 with Medical categories.
A History of Modern Immunology: A Path Toward Understanding describes, analyzes, and conceptualizes several seminal events and discoveries in immunology in the last third of the 20th century, the era when most questions about the biology of the immune system were raised and also found their answers. Written by an eyewitness to this history, the book gives insight into personal aspects of the important figures in the discipline, and its data driven emphasis on understanding will benefit both young and experienced scientists. This book provides a concise introduction to topics including immunological specificity, antibody diversity, monoclonal antibodies, major histocompatibility complex, antigen presentation, T cell biology, immunological tolerance, and autoimmune disease. This broad background of the discipline of immunology is a valuable companion for students of immunology, research and clinical immunologists, and research managers in the pharmaceutical and biotechnology industries. Contains the history of major breakthroughs in immunology featured with authenticity and insider details Gives an insight into personal aspects of the players in the history of immunology Enables the reader to recognize and select data of heuristic value which elucidate important facets of the immune system Provides good examples and guidelines for the recognition and selection of what is important for the exploration of the immune system Gives clear separation of descriptive and interpretive parts, allowing the reader to distinguish between facts and analysis provided by the author
Metchnikoff And The Origins Of Immunology
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Author : Alfred I. Tauber
language : en
Publisher: Oxford University Press
Release Date : 1991-07-25
Metchnikoff And The Origins Of Immunology written by Alfred I. Tauber and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-07-25 with Medical categories.
This fascinating intellectual history is the first critical study of the work of Elie Metchnikoff, the founding father of modern immunology. Metchnikoff authored and championed the theory that phagocytic cells actively defend the host body against pathogens and diseased cells. His program developed from comparative embryological studies that sought to establish genealogical relations between species at the dawn of the Darwinian revolution. In this scientific biography, Tauber and Chernyak explore ore Metchnikoff's development as an embryologist, showing how it prepared him to propose his theory of host-pathogen interaction. They discuss the profound impact of Darwin's theory of evolution on Metchnikoff's progress, and the influence of 19th century debates on vitalism, teleology, and mechanism. As a case study of scientific discovery, this work offers lucid insight into the process of creative science and its dependence on cultural and philosophic sources. Immunologists and historians of science and medicine will find it an absorbing and accessible account of a remarkable individual.
Avian Immunology
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Author : Bernd Kaspers
language : en
Publisher: Academic Press
Release Date : 2012-12-02
Avian Immunology written by Bernd Kaspers and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.
The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research
Species And Specificity
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Author : Pauline M. H. Mazumdar
language : en
Publisher: Cambridge University Press
Release Date : 2002-07-18
Species And Specificity written by Pauline M. H. Mazumdar and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-07-18 with Science categories.
An account of scientific disputes over the core problems of research and practice in immunology.