Aacr 2017 Proceedings Abstracts 1 3062

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Aacr 2017 Proceedings Abstracts 1 3062

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Author : American Association for Cancer Research
language : en
Publisher: CTI Meeting Technology
Release Date : 2017-03-13

Aacr 2017 Proceedings Abstracts 1 3062 written by American Association for Cancer Research and has been published by CTI Meeting Technology this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-13 with Medical categories.

The AACR Annual Meeting highlights the best cancer science and medicine from institutions all over the world. Attendees are invited to stretch their boundaries, form collaborations, attend sessions outside their own areas of expertise, and learn how to apply exciting new concepts, tools, and techniques to their own research. Part A contains abstracts 1-3062 accepted for the 2017 meeting.

Innovations For Next Generation Antibody Drug Conjugates

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Author : Marc Damelin
language : en
Publisher: Humana Press
Release Date : 2018-06-14

Innovations For Next Generation Antibody Drug Conjugates written by Marc Damelin and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-14 with Medical categories.

Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.

Allogeneic Stem Cell Transplantation

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Author : Hillard M. Lazarus
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-02

Allogeneic Stem Cell Transplantation written by Hillard M. Lazarus and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-02 with Medical categories.

Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.

Evolution Of Translational Omics

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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2012-09-13

Evolution Of Translational Omics written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-13 with Science categories.

Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Inflammation And Cancer

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Author : Bharat B. Aggarwal
language : en
Publisher: Springer
Release Date : 2014-05-12

Inflammation And Cancer written by Bharat B. Aggarwal and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-12 with Medical categories.

This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.

Adenosine Receptors

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Author : Gyorgy Hasko
language : en
Publisher: CRC Press
Release Date : 2006-07-20

Adenosine Receptors written by Gyorgy Hasko and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-20 with Medical categories.

After a century of research, several lines of evidence now indicate that the ability of adenosine to directly control inflammatory cells has a major impact on the functions of the inflammatory and immune systems. Consequently, many promising therapeutic approaches are beginning to emerge that focus on the modulation of adenosine, including the deve

Preceptor S Handbook For Pharmacists

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Author : Lourdes M. Cuellar
language : en
Publisher: ASHP
Release Date : 2015-12-18

Preceptor S Handbook For Pharmacists written by Lourdes M. Cuellar and has been published by ASHP this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-18 with Medical categories.

Being a preceptor is hard work. Let ASHP help you become a great leader with the new Preceptor's Handbook for Pharmacists, Third Edition, by Lourdes Cuéllar and Diane Ginsburg. You'll quickly get up to speed on helping students and residents prepare to become effective pharmacists and master patient care. This updated guide will show you how to: Integrate pharmacy students and residents into your practice Improve essential communication, teaching, and leadership skills Motivate and challenge students, set expectations, and acknowledge and understand generational issues and perspectives Establish a professional attitude and bearing in your students Develop your students' cultural competency Grasp essential teaching skills fundamental to your students' success Master the administrative detail of being a pharmacy preceptor Understand the skills needed to mentor pharmacy residents and those in fellowships In the changing world of pharmacy practice, the need for effective preceptors to help prepare both students and residents has never been greater. The Preceptor's Handbook for Pharmacists remains the go-to, authoritative resource for both new and experienced pharmacy preceptors. When you are a preceptor, you create a lifelong impact on young pharmacists.