Adipose Tissue And Cancer
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Adipose Tissue And Cancer
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Author : Mikhail G. Kolonin
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-07-17
Adipose Tissue And Cancer written by Mikhail G. Kolonin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-17 with Medical categories.
Recent studies have shown that cells from adipose tissue are capable of trafficking to tumors, thus enabling paracrine action of adipokines from within the tumor microenvironment. Increased tumor vascularization, immune system suppression and direct effects on malignant cell survival and proliferation have been investigated as mechanisms regulated by adipokines. The goal of this book is to discuss data pointing to the role of adipose tissue in cancer and to dissect individual mechanisms through which adipose tissue excess or restriction could influence cancer progression.
Adipocytokines Energy Balance And Cancer
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Author : Ofer Reizes
language : en
Publisher: Springer
Release Date : 2016-10-31
Adipocytokines Energy Balance And Cancer written by Ofer Reizes and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-31 with Medical categories.
Adipocytokines provide the circuitry by which adipose tissue communicates among its component cells which include adipocytes, stromal cells, immune cells and vascular elements, with adipose tissue depots in other locations throughout the body and with other tissues in order to regulate physiologic processes of energy intake, utilization, and distribution. Since disturbances, both qualitative and quantitative, in adipocytokine function contribute significantly to many of the comorbidities associated with obesity, including diabetes, cardiovascular disease and cancer, this volume, which discusses most of the major adipocytokines independently and collectively and their roles in normal and pathologic processes, should be useful to all individuals seeking a deeper understanding of these processes. Moreover, it provides a valuable complement to the series on Energy Balance and Cancer, in which each volume is focused on a specific aspect of this process, which now constitutes an expanding problem as the obesity pandemic continues and more of the population reaches the age where cancer is most prevalent. This volume should provide a valuable resource to all clinicians and scientists engaged in caring for susceptible patients and in exploring the relation between energy balance and cancer as well as an important platform to providing the background for research development.
Obesity Inflammation And Cancer
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Author : Andrew J. Dannenberg
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-05-21
Obesity Inflammation And Cancer written by Andrew J. Dannenberg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-21 with Medical categories.
In addition to its metabolic and endocrinologic effects, obesity and adipose tissue have now been shown to be associated with low grade inflammation resulting in cellular and humoral inflammatory factors of which the latter may act by endocrine, paracrine and autocrine mechanisms. These inflammatory mediators have increasingly been suggested as contributing to the obesity link to carcinogenesis and cancer promotion. This volume of Energy Balance and Cancer will focus on recent developments and cutting edge research pointing to inflammation and inflammatory factors as key mediators of this linkage. The volume first provides information on inflammation as an important link between obesity and insulin resistance, which is in itself linked to promotion of cancer through hyperinsulinemia. The volume then covers some of the most important mechanisms by which obesity leads to inflammation, including the novel inflammasome concept, alterations in chromatin structure, circulating inflammatory factors, unique cellular interactions between adipocytes and macrophages and the direct link of dietary fat to inflammation and cancer. Overall, this volume will provide important insight to help understand how inflammation may help modulate the linkage between obesity and cancer and serve as a platform for developing future research in this area.
T Cell Alterations In Adipose Tissue During Obesity Hiv And Cancer
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Author : Dorothy Ellen Lewis
language : en
Publisher: Frontiers Media SA
Release Date : 2019-09-25
T Cell Alterations In Adipose Tissue During Obesity Hiv And Cancer written by Dorothy Ellen Lewis and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-25 with categories.
Obesity And Cancer
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Author : Shashank Kumar
language : en
Publisher: Springer Nature
Release Date : 2021-07-18
Obesity And Cancer written by Shashank Kumar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-18 with Medical categories.
This book highlights the concordance between signaling pathways that are involved in obesity and cancer cross-talks. It describes the role of cytokines, chemokines, growth factors, insulin, and adipokines in the development of obesity-associated cancers. The book reviews the role of inflammatory signaling pathways such as estrogen-mediated signaling, mTOR and AMP-activated protein kinase pathway and the involvement of adaptive and innate immunity, oxidative stress, gene polymorphism, dietary phytochemicals, and miRNAs in obesity and cancer. In addition, it covers the latest research on the drugs and natural therapeutic agents that target obesity-induced cancers and discusses various in vivo models for studying obesity and obesity-associated cancer. Lastly, it analyses the role of genetic polymorphisms in the obesity-related genes that influence cancer development. The book is a useful resource for researchers in the field of cancer, pharmacology, food chemistry, and clinical biochemistry.
Adipose Tissue Development
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Author : Claire Levy-Marchal
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2010
Adipose Tissue Development written by Claire Levy-Marchal and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
Nowadays, adipose tissue is not only regarded as an organ of storage related to fuel metabolism but also as an endocrine organ involved in the regulation of insulin sensitivity, lipids and energy metabolism.These proceedings cover the nervous regulation of both white and brown adipose tissue mass. Different physiological parameters such as metabolism (lipolysis and thermogenesis) and secretory activity (leptin and other adipokines) are reviewed. The plasticity of adipose tissue (proliferation, differentiation and apoptosis) showing the presence of a neural feedback loop between adipose tissue and the brain, which plays a major role in the regulation of energy homeostasis, is discussed.Merging basic knowledge and various clinical conditions, this thorough review is of great interest to both scientists and physicians, in particular pediatricians, interested in obesity, endocrinology and nutrition.
Macrosomy Obesity And Cancer
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Author : Lev M. Berstein
language : en
Publisher: Nova Biomedical Books
Release Date : 1996
Macrosomy Obesity And Cancer written by Lev M. Berstein and has been published by Nova Biomedical Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.
Macrosomy, Obesity & Cancer
Adipose Tissue In Health And Disease
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Author : Todd Leff
language : en
Publisher: John Wiley & Sons
Release Date : 2010-03-19
Adipose Tissue In Health And Disease written by Todd Leff and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-19 with Science categories.
This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic. Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue. The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.
Angiogenesis In Adipose Tissue
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Author : Yihai Cao
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-09-05
Angiogenesis In Adipose Tissue written by Yihai Cao and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-05 with Medical categories.
Angiogenesis has recently played a critical role in regulation of adipose tissue expansion and regression. Like most other tissues in the body, adipose expansion and regression is accompanied by alteration of blood vessel density and structures. The vascular alteration plays an active role in regulation of adipose tissue size and functions. Targeting blood vessels in the adipose tissue have demonstrated to be a novel approach for possibly treatment of cancer, obesity and other metabolic diseases. This book provides the most updated information on this type research and discusses future opportunities for therapy..
Adipose Tissue And Adipokines In Health And Disease
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Author : Giamila Fantuzzi
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-06
Adipose Tissue And Adipokines In Health And Disease written by Giamila Fantuzzi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-06 with Medical categories.
This book presents a comprehensive survey of adipose tissue, its physiological functions, and its role in disease. The volume spans the entire range of adipose tissue studies, from basic anatomical and physiological research to epidemiology and clinical studies. Groundbreaking recent studies are incorporated into traditional models of adipose tissue properties. A description of the role of macrophages in obesity and metabolism in included.