Advanced Optical Methods For Brain Imaging


Advanced Optical Methods For Brain Imaging
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Advanced Optical Methods For Brain Imaging


Advanced Optical Methods For Brain Imaging
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Author : Fu-Jen Kao
language : en
Publisher: Springer
Release Date : 2018-05-14

Advanced Optical Methods For Brain Imaging written by Fu-Jen Kao and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-14 with Technology & Engineering categories.


This book highlights the rapidly developing field of advanced optical methods for structural and functional brain imaging. As is known, the brain is the most poorly understood organ of a living body. It is indeed the most complex structure in the known universe and, thus, mapping of the brain has become one of the most exciting frontlines of contemporary research. Starting from the fundamentals of the brain, neurons and synapses, this book presents a streamlined and focused coverage of the core principles, theoretical and experimental approaches, and state-of-the-art applications of most of the currently used imaging methods in brain research. It presents contributions from international leaders on different photonics-based brain imaging modalities and techniques. Included are comprehensive descriptions of many of the technology driven spectacular advances made over the past few years that have allowed novel insights of the structural and functional details of neurons. The book is targeted at researchers, engineers and scientists who are working in the field of brain imaging, neuroscience and connectomics. Although this book is not intended to serve as a textbook, it will appeal to undergraduate students engaged in the specialization of brain imaging.



Imaging The Brain With Optical Methods


Imaging The Brain With Optical Methods
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Author : Anna W. Roe
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-11-11

Imaging The Brain With Optical Methods written by Anna W. Roe and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-11 with Medical categories.


Monitoring brain function with light in vivo has become a reality. The technology 33 of detecting and interpreting patterns of reflected light has reached a degree of 34 maturity that now permits high spatial and temporal resolution visualization at both 35 the systems and cellular levels. There now exist several optical imaging methodolo- 36 gies, based on either hemodynamic changes in nervous tissue or neurally induced 37 light scattering changes, that can be used to measure ongoing activity in the brain. 38 These include the techniques of intrinsic signal optical imaging, near-infrared optical 39 imaging, fast optical imaging based on scattered light, optical imaging with voltage 40 sensitive dyes, and two-photon imaging of hemodynamic signals. The purpose of 41 this volume is to capture some of the latest applications of these methodologies to 42 the study of cerebral cortical function. 43 This volume begins with an overview and history of optical imaging and its use 44 in the study of brain function. Several chapters are devoted to the method of intrin- 45 sic signal optical imaging, a method used to record the minute changes in optical 46 absorption due to hemodynamic changes that accompanies cortical activity. Since the 47 detected hemodynamic changes are highly localized, this method has excellent 48 spatial resolution (50–100 μm ), a resolution sufficient for visualization of fundamen- 49 tal modules of cerebral cortical function.



Optical Methods And Instrumentation In Brain Imaging And Therapy


Optical Methods And Instrumentation In Brain Imaging And Therapy
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Author : Steen J. Madsen
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-13

Optical Methods And Instrumentation In Brain Imaging And Therapy written by Steen J. Madsen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-13 with Science categories.


This book provides a comprehensive up-to-date review of optical approaches used in brain imaging and therapy. It covers a variety of imaging approaches including diffuse optical imaging, laser speckle imaging, photoacoustic imaging and optical coherence tomography. A number of laser-based therapeutic techniques are reviewed, including photodynamic therapy, fluorescence guided resection and photothermal therapy. Fundamental principles and instrumentation are discussed for each imaging and therapeutic approach.



In Vivo Optical Imaging Of Brain Function Second Edition


In Vivo Optical Imaging Of Brain Function Second Edition
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Author : Ron D. Frostig
language : en
Publisher: CRC Press
Release Date : 2009-05-06

In Vivo Optical Imaging Of Brain Function Second Edition written by Ron D. Frostig and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-06 with Science categories.


These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques and their applications for the growing field of functional imaging in the live brain using optical imaging techniques. New in the Second Edition: Voltage-sensitive dyes imaging in awake behaving animals Imaging based on genetically encoded probes Imaging of mitochondrial auto-fluorescence as a tool for cortical mapping Using pH-sensitive dyes for functional mapping Modulated imaging Calcium imaging of neuronal activity using 2-photon microscopy Fourier approach to optical imaging Fully updated chapters from the first edition Leading Authorities Explore the Latest Techniques Updated to reflect continuous development in this emerging research area, this new edition, as with the original, reaches across disciplines to review a variety of non-invasive optical techniques used to study activity in the living brain. Leading authorities from such diverse areas as biophysics, neuroscience, and cognitive science present a host of perspectives that range from a single neuron to large assemblies of millions of neurons, captured at various temporal and spatial resolutions. Introducing techniques that were not available just a few years ago, the authors describe the theory, setup, analytical methods, and examples that highlight the advantages of each particular method.



Advances In Brain Imaging Techniques


Advances In Brain Imaging Techniques
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Author : Nirmal Mazumder
language : en
Publisher: Springer Nature
Release Date : 2022-05-19

Advances In Brain Imaging Techniques written by Nirmal Mazumder and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-19 with Medical categories.


The book reviews the recent developments in brain imaging and their technological advancements to understand molecular mechanisms associated with neurological disorders and basic behaviors in humans and rodents at the structural, molecular, and functional levels. It discusses the usefulness of advanced optical microscopy techniques, including optical coherence tomography (OCT), miniscope, multiphoton fluorescence (2PF & 3PF), adaptive optics, harmonic generation, and Raman microscopy for understanding pathomechanism of brain disorders and pathological and physiological changes associated with neurodegenerative diseases. Also, the book presents conventional imaging modalities, including Magnetic Resonance Imaging (MRI), for delineating underlying mechanisms and precise early diagnosis of neurological disorders. This book is a useful resource for neuroscientists and researchers working in biomedical engineering and optics.



Advanced Imaging Methods In Neuroscience


Advanced Imaging Methods In Neuroscience
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Author : João O. Malva
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-11

Advanced Imaging Methods In Neuroscience written by João O. Malva and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-11 with Science categories.




Handbook Of Neurophotonics


Handbook Of Neurophotonics
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Author : Francesco S. Pavone
language : en
Publisher: CRC Press
Release Date : 2020-05-10

Handbook Of Neurophotonics written by Francesco S. Pavone and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-10 with Medical categories.


The Handbook of Neurophotonics provides a dedicated overview of neurophotonics, covering the use of advanced optical technologies to record, stimulate, and control the activity of the brain, yielding new insight and advantages over conventional tools due to the adaptability and non-invasive nature of light. Including 32 colour figures, this book addresses functional studies of neurovascular signaling, metabolism, electrical excitation, and hemodynamics, as well as clinical applications for imaging and manipulating brain structure and function. The unifying theme throughout is not only to highlight the technology, but to show how these novel methods are becoming critical to breakthroughs that will lead to advances in our ability to manage and treat human diseases of the brain. Key Features: Provides the first dedicated book on state-of-the-art optical techniques for sensing and imaging across at the cellular, molecular, network, and whole brain levels. Highlights how the methods are used for measurement, control, and tracking of molecular events in live neuronal cells, both in basic research and clinical practice. Covers the entire spectrum of approaches, from optogenetics to functional methods, photostimulation, optical dissection, multiscale imaging, microscopy, and structural imaging. Includes chapters that show use of voltage-sensitive dye imaging, hemodynamic imaging, multiphoton imaging, temporal multiplexing, multiplane microscopy, optoacoustic imaging, near-infrared spectroscopy, and miniature neuroimaging devices to track cortical brain activity.



Advances In Optical Imaging For Clinical Medicine


Advances In Optical Imaging For Clinical Medicine
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Author : Nicusor Iftimia
language : en
Publisher: John Wiley & Sons
Release Date : 2011-04-27

Advances In Optical Imaging For Clinical Medicine written by Nicusor Iftimia and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-27 with Science categories.


This book provides students, teachers, researchers and clinicians with a strong and established source of information on advanced optical technologies that show real promise of being translated to clinical use.



Dynamic Brain Imaging


Dynamic Brain Imaging
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Author : Hyder Fahmeed
language : en
Publisher: Humana Press
Release Date : 2008-11-01

Dynamic Brain Imaging written by Hyder Fahmeed and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-01 with Medical categories.


If a picture is worth a thousand words, then dynamic images of brain activity certainly warrant many, many more. This book will help users learn to decipher the dynamic imaging data that will be critical to our future understanding of complex brain functions. In recent years, there have been unprecedented methodological advancements in the imaging of brain activity. These techniques allow the measurement of everything from neural activity (e.g., membrane potential, ion ?ux, neurotransmitter ?ux) to energy metabolism (e.g., glucose consumption, oxygen consumption, creatine kinase ?ux) and functional hyperemia (e.g., blood ?ow, volume, oxygenation). This book deals with a variety of magnetic resonance, electrophysiology, and optical methods that are often used to measure some of these dynamic processes. All chapters were written by leading experts, spanning three continents, specializing in state-of-the-art methods. Brie?y, the book has ?ve sections. In the introductory section, there are two chapters; the ?rst one contains a brief pre- ble to dynamic brain imaging and the other presents a novel, analytical approach to processing of dynamically acquired data. The second section has four chapters and delves into a wide range of optical imaging methods. I am privileged to include a chapter from Lawrence B. Cohen, considered by many to be the authority on optical imaging and spectroscopy, both in vitro and in vivo [Cohen LB (1973) Physiol Rev.



Optical Imaging Of Brain Function And Metabolism


Optical Imaging Of Brain Function And Metabolism
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Author : Ulrich Dirnagl
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-21

Optical Imaging Of Brain Function And Metabolism written by Ulrich Dirnagl and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-21 with Medical categories.


• . . . . At last the doctor will be freed from the tedious interpretation of screens and photographs. Instead, he will examine and scan through his patient directly. Wearing optical-shutter spectacles and aiming a pulsed laser torch, he will be able to peer at the beating heart, study the movement of a joint or the flexing of a muscle, press on suspect areas to see how the organs beneath respond, check that pills have been correctly swallowed or that an implant is savely in place, and so on. A patient wearing white cotton or nylon clothes that scatter but hardly absorb light, may not even have to undress . . . . •. David Jones, Nature (1990) 348:290 Optical imaging of the brain is a rapidly growing field of heterogenous techniques that has attracted considerable interest recently due to a number of theoretical advantages in comparison with other brain imaging modalities: it uses non ionizing radiation, offers high spatial and temporal resolution, and supplies new types of metabolic and functional information. From a practical standpoint it is important that bedside examinations seem feasible and that the implementations will be considerably less expensive compared with competing techniques. In October 1991, a symposium was held at the Eibsee near Garmisch, Germany to bring together the leading scientists in this new field.