Advances In Bioinformatics Biostatistics And Omic Sciences

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Advances In Bioinformatics Biostatistics And Omic Sciences

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Author : Luigi Donato
language : en
Publisher: Bentham Science Publishers
Release Date : 2020-11-30

Advances In Bioinformatics Biostatistics And Omic Sciences written by Luigi Donato and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-30 with Computers categories.

Bioinformatics, and by extension omic sciences – the collective disciplines that are dependent on the use of extensive datasets of biological information – present a challenge of data management for researchers all over the world. Big data collected as part of research projects and experiments can be complex, with several kinds of variables involved. Coupled with continuously changing bioinformatics and information technology tools, there is a need to bring a multidisciplinary approach into these fields. Advances in Bioinformatics, Biostatistics and Omic Sciences attempts to realize an integrated approach between all omic sciences, exploring innovative bioinformatics and biostatistical methodologies which enable researchers to unveil hidden sides of biological phenomena. This volume presents reviews on the following topics which give a glimpse of recent advances in the field: - New Integrated Mitochondrial DNA Bioinformatics Pipeline to Improve Quality Assessment of Putative Pathogenic Variants from NGS Experiments - Variant Calling on RNA Sequencing Data: State of Art and Future Perspectives - An innovative Gene Prioritization Pipeline for WES analyses - New Integrated Differential Expression Approach for RNA-Seq Data Analysis - Innovations in Data Visualization for Straightforward Interpretation of Nucleic Acid Omics Outcomes This volume serves as a guide for graduate students in bioinformatics as well as researchers planning new projects as a part of their professional and academic activities.

Bioinformatics

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Author : M. H. Fulekar
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-03-24

Bioinformatics written by M. H. Fulekar and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-24 with Computers categories.

Bioinformatics, computational biology, is a relatively new field that applies computer science and information technology to biology. In recent years, the discipline of bioinformatics has allowed biologists to make full use of the advances in Computer sciences and Computational statistics for advancing the biological data. Researchers in life sciences generate, collect and need to analyze an increasing number of different types of scientific data, DNA, RNA and protein sequences, in-situ and microarray gene expression including 3D protein structures and biological pathways. This book is aiming to provide information on bioinformatics at various levels. The chapters included in this book cover introductory to advanced aspects, including applications of various documented research work and specific case studies related to bioinformatics. This book will be of immense value to readers of different backgrounds such as engineers, scientists, consultants and policy makers for industry, government, academics and social and private organisations.

Statistical Analysis Of Proteomics Metabolomics And Lipidomics Data Using Mass Spectrometry

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Author : Susmita Datta
language : en
Publisher: Springer
Release Date : 2016-12-22

Statistical Analysis Of Proteomics Metabolomics And Lipidomics Data Using Mass Spectrometry written by Susmita Datta and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-22 with Medical categories.

This book presents an overview of computational and statistical design and analysis of mass spectrometry-based proteomics, metabolomics, and lipidomics data. This contributed volume provides an introduction to the special aspects of statistical design and analysis with mass spectrometry data for the new omic sciences. The text discusses common aspects of design and analysis between and across all (or most) forms of mass spectrometry, while also providing special examples of application with the most common forms of mass spectrometry. Also covered are applications of computational mass spectrometry not only in clinical study but also in the interpretation of omics data in plant biology studies. Omics research fields are expected to revolutionize biomolecular research by the ability to simultaneously profile many compounds within either patient blood, urine, tissue, or other biological samples. Mass spectrometry is one of the key analytical techniques used in these new omic sciences. Liquid chromatography mass spectrometry, time-of-flight data, and Fourier transform mass spectrometry are but a selection of the measurement platforms available to the modern analyst. Thus in practical proteomics or metabolomics, researchers will not only be confronted with new high dimensional data types—as opposed to the familiar data structures in more classical genomics—but also with great variation between distinct types of mass spectral measurements derived from different platforms, which may complicate analyses, comparison, and interpretation of results.

Evolution Of Translational Omics

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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2012-09-13

Evolution Of Translational Omics written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-13 with Science categories.

Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Advanced Methodologies And Technologies In Medicine And Healthcare

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Author : Khosrow-Pour, D.B.A., Mehdi
language : en
Publisher: IGI Global
Release Date : 2018-10-05

Advanced Methodologies And Technologies In Medicine And Healthcare written by Khosrow-Pour, D.B.A., Mehdi and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-05 with Medical categories.

Advancements in medical and healthcare technologies pave the way to improving treatments and diagnoses while also streamlining processes to ensure the highest quality care is given to patients. In the last few decades, revolutionary technology has radically progressed the healthcare industry by increasing life expectancy and reducing human error. Advanced Methodologies and Technologies in Medicine and Healthcare provides emerging research on bioinformatics, medical ethics, and clinical science in modern applications and settings. While highlighting the challenges medical practitioners and healthcare professionals face when treating patients and striving to optimize their processes, the book shows how revolutionary technologies and methods are vastly improving how healthcare is implemented globally. This book is an important resource for medical researchers, healthcare administrators, doctors, nurses, biomedical engineers, and students looking for comprehensive research on the advancements in healthcare technologies.

Advanced Statistical Methods In Life Science

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Author : Basavarajaiah D.M
language : en
Publisher: CRC Press
Release Date : 2025-07-25

Advanced Statistical Methods In Life Science written by Basavarajaiah D.M and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-25 with Mathematics categories.

This book introduces the principles and foundations of advanced statistical methods for designing experiments and testing hypotheses in life sciences. Advanced statistical methods, such as testing of hypotheses, recent methods of sample size determination/imputation, estimation techniques, probability distributions, and univariate analysis demonstrated with real data, and their integration into life sciences are included in this book. Advanced topics are presented with sufficient conceptual depth and examples to explain the use of recent statistical techniques and to demonstrate what conclusions can be drawn at the right time using modeling in life science research. Key features: Explains the derivation of statistical models to prove disease transmission using massive real-world datasets to explore practical applicability Incorporates the application of innovative advanced statistical and epidemiological models and demonstrates the possible solutions for public health policy intervention Helps to understand the process of hypothesis testing in small or larger observations by using weighted parameters Presents suitable examples and real-life research datasets, and all models can easily be followed in formulating statistical and mathematical derivations and key points Includes machine learning (ML), statistical methods for meta-analysis, testing of hypotheses, methods of imputation, estimation techniques, probability distributions, univariate analysis, and recent nonparametric methods, all illustrated through actual data This textbook is for students and scholars of various courses in life sciences, medicine, mathematics, and statistical science. It will also help academicians and researchers to understand the foundation of this topic.

Computational Intelligence Methods For Bioinformatics And Biostatistics

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Author : Claudia Angelini
language : en
Publisher: Springer
Release Date : 2016-07-30

Computational Intelligence Methods For Bioinformatics And Biostatistics written by Claudia Angelini and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-30 with Computers categories.

This book constitutes the thoroughly refereed post-conference proceedings of the 12th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2015, held in Naples, Italy, in September, 2015. The 21 revised full papers presented were carefully reviewed and selected from 24 submissions. They present problems concerning computational techniques in bioinformatics, systems biology and medical informatics discussing cutting edge methodologies and accelerate life science discoveries, as well as novel challenges with an high impact on molecular biology and translational medicine.

Advances In Genetics

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Author :
language : en
Publisher: Academic Press
Release Date : 2016-02-23

Advances In Genetics written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-23 with Science categories.

Advances in Genetics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions. - Critically analyzes future directions for the study of clinical genetics - Written and edited by recognized leaders in the field - Presents new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics

Essentials Of Bioinformatics Volume Iii

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Author : Khalid Rehman Hakeem
language : en
Publisher: Springer Nature
Release Date : 2019-11-01

Essentials Of Bioinformatics Volume Iii written by Khalid Rehman Hakeem and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-01 with Science categories.

Bioinformatics is an integrative field of computer science, genetics, genomics, proteomics, and statistics, which has undoubtedly revolutionized the study of biology and medicine in past decades. It mainly assists in modeling, predicting and interpreting large multidimensional biological data by utilizing advanced computational methods. Despite its enormous potential, bioinformatics is not widely integrated into the academic curriculum as most life science students and researchers are still not equipped with the necessary knowledge to take advantage of this powerful tool. Hence, the primary purpose of our book is to supplement this unmet need by providing an easily accessible platform for students and researchers starting their career in life sciences. This book aims to avoid sophisticated computational algorithms and programming. Instead, it will mostly focus on simple DIY analysis and interpretation of biological data with personal computers. Our belief is that once the beginners acquire these basic skillsets, they will be able to handle most of the bioinformatics tools for their research work and to better understand their experimental outcomes. The third volume is titled In Silico Life Sciences: Agriculture. It focuses on plant genetic, genomic, transcriptomic, proteomic and metabolomics data. Using examples of new crop diseases-emergence, crop productivity and biotic/abiotic stress tolerance, this book illustrates how bioinformatics can be an integral components of modern day plant science research.

Computational Intelligence Methods For Bioinformatics And Biostatistics

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Author : Paolo Cazzaniga
language : en
Publisher: Springer Nature
Release Date : 2020-12-09

Computational Intelligence Methods For Bioinformatics And Biostatistics written by Paolo Cazzaniga and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-09 with Computers categories.

This book constitutes revised selected papers from the 16th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2019, which was held in Bergamo, Italy, during September 4-6, 2019. The 28 full papers presented in this volume were carefully reviewed and selected from 55 submissions. The papers are grouped in topical sections as follows: Computational Intelligence Methods for Bioinformatics and Biostatistics; Algebraic and Computational Methods for the Study of RNA Behaviour; Intelligence methods for molecular characterization medicine; Machine Learning in Healthcare Informatics and Medical Biology; Modeling and Simulation Methods for Computational Biology and Systems Medicine.