Advances In The Understanding Of Biological Sciences Using Next Generation Sequencing Ngs Approaches
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Advances In The Understanding Of Biological Sciences Using Next Generation Sequencing Ngs Approaches
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Author : Gaurav Sablok
language : en
Publisher: Springer
Release Date : 2015-07-16
Advances In The Understanding Of Biological Sciences Using Next Generation Sequencing Ngs Approaches written by Gaurav Sablok and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-16 with Science categories.
Provides a global view of the recent advances in the biological sciences and the adaption of the pathogen to the host plants revealed using NGS. Molecular Omic’s is now a major driving force to learn the adaption genetics and a great challenge to the scientific community, which can be resolved through the application of the NGS technologies. The availability of complete genome sequences, the respective model species for dicot and monocot plant groups, presents a global opportunity to delineate the identification, function and the expression of the genes, to develop new tools for the identification of the new genes and pathway identification. Genome-wide research tools, resources and approaches such as data mining for structural similarities, gene expression profiling at the DNA and RNA level with rapid increase in available genome sequencing efforts, expressed sequence tags (ESTs), RNA-seq, gene expression profiling, induced deletion mutants and insertional mutants, and gene expression knock-down (gene silencing) studies with RNAi and microRNAs have become integral parts of plant molecular omic’s. Molecular diversity and mutational approaches present the first line of approach to unravel the genetic and molecular basis for several traits, QTL related to disease resistance, which includes host approaches to combat the pathogens and to understand the adaptation of the pathogen to the plant host. Using NGS technologies, understanding of adaptation genetics towards stress tolerance has been correlated to the epigenetics. Naturally occurring allelic variations, genome shuffling and variations induced by chemical or radiation mutagenesis are also being used in functional genomics to elucidate the pathway for the pathogen and stress tolerance and is widely illustrated in demonstrating the identification of the genes responsible for tolerance in plants, bacterial and fungal species.
Next Generation Sequencing
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Author : Jerzy Kulski
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-01-14
Next Generation Sequencing written by Jerzy Kulski and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-14 with Medical categories.
Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.
The Spruce Genome
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Author : Ilga M. Porth
language : en
Publisher: Springer Nature
Release Date : 2020-08-01
The Spruce Genome written by Ilga M. Porth and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-01 with Science categories.
This book offers comprehensive information on the genomics of spruces (Picea spp.), naturally abundant conifer tree species that are widely distributed in the Northern Hemisphere. Due to their tremendous ecological and economic importance, the management of forest genetic resources has chiefly focused on conservation and tree improvement. A draft genome sequence of the 20-gigabase Norway spruce genome was published in the journal Nature in 2013. Continuous efforts to improve the spruce genome assembly are underway, but are hindered by the inherent characteristics of conifer genomes: high amounts of repetitive sequences (introns and transposable elements) in the genome and large gene family expansions with regards to abiotic stress, secondary metabolism and spruces' defense responses to pathogens and herbivory. This book presents the latest information on the status of genome assemblies, provides detailed insights into transposable elements and methylation patterns, and highlights the extensive genomic resources available for inferring population genomics and climate adaptation, as well as emerging genomics tools for tree improvement programs. In addition, this volume features whole-genome comparisons among conifer species, and demonstrates how functional genomics can be used to improve gene function annotations. The book closes with an outlook on emerging fields of research in spruce genomics.
Clinical Applications For Next Generation Sequencing
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Author : Urszula Demkow
language : en
Publisher: Academic Press
Release Date : 2015-09-10
Clinical Applications For Next Generation Sequencing written by Urszula Demkow and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-10 with Science categories.
Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments. Rooted in both medical genetics and clinical medicine, the book fills the gap between state-of-the-art technology and evidence-based practice, providing an educational opportunity for users to advance patient care by transferring NGS to the needs of real-world patients. The book builds an interface between genetic laboratory staff and clinical health workers to not only improve communication, but also strengthen cooperation. Users will find valuable tactics they can use to build a systematic framework for understanding the role of NGS testing in both common and rare diseases and conditions, from prenatal care, like chromosomal abnormalities, up to advanced age problems like dementia. - Fills the gap between state-of-the-art technology and evidence-based practice - Provides an educational opportunity which advances patient care through the transfer of NGS to real-world patient assessment - Promotes a practical tool that clinicians can apply directly to patient care - Includes a systematic framework for understanding the role of NGS testing in many common and rare diseases - Presents evidence regarding the important role of NGS in current diagnostic strategies
Omics And Genome Editing
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Author : Kartika Sharma
language : en
Publisher: Springer Nature
Release Date : 2025-03-15
Omics And Genome Editing written by Kartika Sharma and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-15 with Science categories.
This book offers up-to-date research on genome editing and omics technologies from renowned academics with established backgrounds from throughout the globe. The world population is expected to touch 9–10 billion by 2050 and to feed the growing population, 50% more food must be produced globally than is currently produced. Nonetheless, it is a difficult challenge to increase the food output of the currently existing crops on available land. Over the past few decades, traditional crop enhancement techniques like plant breeding and other agricultural technology have made a significant contribution to food and nutritional security. With the use of strong technologies, genome editing strategies can significantly improve the productivity and efficiency of current agricultural practices. Discovering the underlying mechanisms influencing features of economic value has been made possible through genome editing through CRISPR/Cas9, primer and base editing, and OMICs through genomics, proteomics, metabolomics, transcriptomics, and phenomics. This book provides a wealth of information on omics and genome editing approaches and their application to develop abiotic, biotic, and climate-tolerant crops, as well as RNA interference, next-generation sequencing, and metabolomics for sustainable crop production. Researchers are actively using both genome editing and omics for crop improvement; however, there is limited literature offered in a single source. Undergraduate and postgraduate students, researchers, policymakers, and stakeholders will find this book to be an invaluable resource.
Plant Genetics And Biotechnology In Biodiversity
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Author : Rosa Rao
language : en
Publisher: MDPI
Release Date : 2018-08-09
Plant Genetics And Biotechnology In Biodiversity written by Rosa Rao and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-09 with Science categories.
This book is a printed edition of the Special Issue "Plant Genetics and Biotechnology in Biodiversity" that was published in Diversity
The Date Palm Genome Vol 2
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Author : Jameel M. Al-Khayri
language : en
Publisher: Springer Nature
Release Date : 2021-06-12
The Date Palm Genome Vol 2 written by Jameel M. Al-Khayri and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-12 with Science categories.
This book is the first comprehensive assemblage of contemporary knowledge relevant to genomics and other omics in date palm. Volume 2 consists of 11 chapters. Part I, Nutritional and Pharmaceuticals Properties, covers the utilization of date palm as an ingredient of various food products, a source of bioactive compounds and the production of nanomaterials. Part II, Omics Technologies, addresses omics resources, proteomics and metabolomics. Part III, Molecular Breeding and Genome Modification, focuses on genetic improvement technologies based on mutagenesis, quantitative traits loci and genome editing. Part IV, Genomics of Abiotic and Biotic Stress, covers metagenomics of beneficial microbes to enhance tolerance to abiotic stress and the various genomics advances as they apply to insect control. This volume represents the efforts of 34 international scientists from 12 countries and contains 65 figures and 19 tables to illustrate presented concepts. Volume 1 is published under the title: Phylogeny, Biodiversity and Mapping.
Bioinformatics In Rice Research
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Author : Manoj Kumar Gupta
language : en
Publisher: Springer Nature
Release Date : 2021-09-24
Bioinformatics In Rice Research written by Manoj Kumar Gupta and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-24 with Science categories.
This book provides an up-to-date review of classic and advanced bioinformatics approaches and their utility in rice research. It summarizes databases and tools for analyzing DNA, proteins and gene expression profiles, mapping genetic variations, annotation of protein and RNA molecules, phylogenetic analysis, and pathway enrichment. In addition, it presents high-throughput technologies that are widely used to provide deep insights into the genetic architecture of important traits in the rice genome. The book subsequently discusses techniques for identifying RNA-protein, DNA-protein interactions, and molecular markers, including SNP and microsatellites, in the contexts of rice breeding and genetics. Lastly, it explores various tools that are used to identify and characterize non-coding RNA in rice and their potential role in rice research.
Somatic Embryogenesis Fundamental Aspects And Applications
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Author : Víctor M Loyola-Vargas
language : en
Publisher: Springer
Release Date : 2016-06-06
Somatic Embryogenesis Fundamental Aspects And Applications written by Víctor M Loyola-Vargas and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-06 with Science categories.
This book discusses basic and applied aspects of somatic embryogenesis, one of the most powerful tools in plant biotechnology. It is divided into three parts; Part I includes topics such as the history of this research field, how differentiated plant cells can (re)acquire totipotency, molecular features, as well as the epigenetics and proteomics of somatic embryogenesis. Part II covers the somatic embryogenesis of different crops, such as Agave spp. maize, Cocos nucifera, Bixa orellana, Capsicum spp., Coffea spp., Musa spp., Pinus spp., and Arabidopsis thaliana. Various applications, like scale-up propagation and genetic engineering are discussed in detail in Part III. The book will appeal to plant scientists, plant breeders and experts working in industry.
More Food Road To Survival
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Author : Roberto Pilu
language : en
Publisher: Bentham Science Publishers
Release Date : 2017-06-16
More Food Road To Survival written by Roberto Pilu and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-16 with Technology & Engineering categories.
More Food: Road to Survival is a comprehensive analysis of agricultural improvements which can be achieved through scientific methods. This reference book gives information about strategies for increasing plant productivity, comparisons of agricultural models, the role of epigenetic events on crop production, yield enhancing physiological events (photosynthesis, germination, seedling emergence, seed properties, etc.), tools enabling efficient exploration of genetic variability, domestication of new species, the detection or induction of drought resistance and apomixes and plant breeding enhancement (through molecularly assisted breeding, genetic engineering, genome editing and next generation sequencing). The book concludes with a case study for the improvement of small grain cereals. Readers will gain an understanding of the biotechnological tools and concepts central to sustainable agriculture More Food: Road to Survival is, therefore, an ideal reference for agriculture students and researchers as well as professionals involved sustainability studies.