Airway Smooth Muscle In Health And Disease
DOWNLOAD
Download Airway Smooth Muscle In Health And Disease PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Airway Smooth Muscle In Health And Disease book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Airway Smooth Muscle In Health And Disease
DOWNLOAD
Author : R.F. Coburn
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Airway Smooth Muscle In Health And Disease written by R.F. Coburn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
I organized this book because there is a need to put together in book form recent advances in our knowledge of how airway smooth muscle:works in health and in disease. After a period when it seemed that progress was very slow, there has been in the past few years an incredibly rapid gathering of knowledge in this area. In particular, our understanding has improved regarding the cascades of events that follow the initial binding of agonist to plasma membrane receptors and that lead to the cross-bridge movements that determine contraction. This advance in our knowledge was stimulated by use of single-and whole-cell channel recordings of plasma membrane currents and by description of the l3-receptor-GTP-binding protein-adenylate cyclase-cAMP coupling system, which serves as a model for other coupling mechanisms. The discovery of the receptor-activated inositol phospholipid transduction system has greatly stimulated research and led to advances in our understanding of mechanisms involved in smooth muscle con traction. Major advances were also triggered by the development of indicators for measuring free cytosolic calcium concentration and starting the unraveling of 2 the events involved in Ca + -dependent activation of contractile proteins. Al though most of the studies that led to our current understanding of these areas were performed on nonairway smooth muscle, these studies usually add to our understanding of airway smooth muscle, and there is an enlarging body of data that have been obtained on airway smooth muscle.
Airway Smooth Muscle In Asthma And Copd
DOWNLOAD
Author : Kian Fan Chung
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-30
Airway Smooth Muscle In Asthma And Copd written by Kian Fan Chung and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Science categories.
In this book, leading researchers in medicine and molecular pharmacology explain the cellular mechanisms that control airway smooth muscle. The means by which these are disrupted in disease, and the pharmacologic strategies by which they may be modified are discussed and future therapeutic interventions are identified. Aimed at specialists in pulmonology, this volume provides the clinician with the most up to date information on one of the core physiological processes in airway disease, and offers insights into current and future approaches to management. Authoritative update on key mechanisms of airway constriction in Asthma and COPD Relates latest research to bronchodilator therapy Multi-contributed text, co-coordinated by two of the leading authorities in the field.
Smooth Muscle Spontaneous Activity
DOWNLOAD
Author : Hikaru Hashitani
language : en
Publisher: Springer
Release Date : 2019-06-10
Smooth Muscle Spontaneous Activity written by Hikaru Hashitani and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-10 with Medical categories.
This book presents the commonality and heterogeneity of the mechanisms underlying smooth muscle spontaneous activity in various smooth muscle organs and in addition discusses their malfunctions in disease and their potential as novel therapeutic targets. To facilitate understanding, the volume is divided into five parts and covers 16 organs: airways, gastrointestinal tract (phasic muscle, tonic muscle), renal pelvis, ureter, urinary bladder, urethra, corporal tissue, prostate, uterus, oviducts, seminal vesicle, artery, vein, microvasculature, and lymphatic vessels. This structure will help readers to comprehend the most up-to-date information on the similarities and differences in the contractile mechanisms driving various smooth muscles as well as their potential manipulations in particular visceral organ pathologies. The vast advancements in gene, electrical recording, and imaging technologies in this field are also discussed, with review of past achievements and consideration of likely future developments. This book will be of worldwide interest to clinicians, students, and researchers alike.
Airways Smooth Muscle Biochemical Control Of Contraction And Relaxation
DOWNLOAD
Author : David Raeburn
language : en
Publisher: Birkhäuser
Release Date : 2013-11-11
Airways Smooth Muscle Biochemical Control Of Contraction And Relaxation written by David Raeburn and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
Airway Smooth Muscle
DOWNLOAD
Author : Devendra K. Agrawal
language : en
Publisher: CRC Press
Release Date : 1990-10-24
Airway Smooth Muscle written by Devendra K. Agrawal and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-10-24 with Medical categories.
Airway smooth muscle plays a dominant role in bronchial asthma, as well as a significant role in various pulmonary diseases, such as chronic bronchitis, cystic fibrosis and emphysema. Myogenic, neurogenic, and humoral factors control airway smooth-muscle tone. This text provides a state-of-the-art summary and critical discussion of airway smooth muscle from a multidisciplinary point of view. Topics discussed include morphology, biochemical regulation, mechanical and electrophysiological behavior and reflex control of smooth muscle; the epithelium-derived relaxing factor; and methods to measure smooth muscle function in vivo in humans and experimental animals, as well as in vitro in isolated airway tissues. Also discussed are calcium and potassium channels and receptors for adrenergic, cholinergic and histaminergic systems in modulating receptor-response coupling in airway smooth muscle. Airway Smooth Muscle: Modulation of Receptors and Response provides essential information for researchers, teachers, pulmonary specialists and allergists, and students interested in learning about airway smooth muscle.
Airway Calibre In Health And Disease
DOWNLOAD
Author : Alastair Heriot Campbell
language : en
Publisher: Elsevier Publishing Company
Release Date : 1988
Airway Calibre In Health And Disease written by Alastair Heriot Campbell and has been published by Elsevier Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medical categories.
Airways Smooth Muscle
DOWNLOAD
Author : David Raeburn
language : en
Publisher: Birkhäuser
Release Date : 2013-03-09
Airways Smooth Muscle written by David Raeburn and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
Many factors may influence the release of neurotransmitters from airway nerves [1]. This is likely to be important in physiological control of airway functions and may be particularly relevant in airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD). Neural elements in airways interact in a complex manner and the activation of certain neural pathways may profoundly influence the release of transmitters from other neural pathways. Similarly inflamma tory mediators released from inflammatory cells in the airways may also modulate neurotransmitter release. There are marked differences be tween species in airway innervation and in neuromodulatory effects and, wherever possible, studies in human airways have been emphasised, although information on neuromodulation in human airways is some what limited at present. Release of neurotransmitters from nerve terminals occurs via a Ca2+ dependent secretion evoked by a nerve action potential, but may also be evoked experimentally by a high extracellular K + concentration which directly depolarises the nerve terminal membrane. Modulation refers to the alteration of neurotransmitter release, which may either be increased (facilitation) or reduced (inhibition) by the action of a particular agent, thus changing the magnitude of the neurally-mediated response. Such agents would normally act on receptors on the nerve terminal which are referred to as pre-junctional (or presynaptic) receptors, in contrast to post-junctional (or post-synaptic) receptors located on the target cells which are influenced by that particular transmitter.
Pulmonary Biology In Health And Disease
DOWNLOAD
Author : Edward E. Bittar
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-28
Pulmonary Biology In Health And Disease written by Edward E. Bittar and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-28 with Science categories.
Pulmonary Biology in Health and Disease was conceived as a companion to a handful of expensive, multivolume textbooks. This is part of the promising trend to publish shorter textbooks on the subjects of lung biology and remodeling. Whoever is familiar with human biology and the far-reaching consequences of the genome and postgenome revolutions is apt to concede that the centerpiece in remodeling lies in the ?eld of m- ecular cardiobiology. The ?eld of molecular cardiobiology includes the syndrome of chronic heart failure as well as ischemic cardioprotection. By analogy, the centerpiece in pulmonobiology is chronic asthma. Key topics in the present volume include s- naling mechanisms regulating the endothelium and smooth muscle cells,in?ammatory cells, mediators, airway surface liquid, and pharmacological therapy that focuses on how in?amed airways are altered. Written primarily for predoctoral and postdoctoral graduates in the basic medical sciences, the medical student and postdoctoral physician, graduates in the allied s- ences, nurses, pulmonologists, and physicians in critical care medicine, this book p- vides many of the fundamentals of contemporary pulmonology. It is divided into several parts devoted to the control of respiration, arterial chemoreceptors,muscles of ventilation, pulmonary physiology, and gas exchange in health, exercise, and disease. Special emphasis is placed on emphysema and its pathobiology, acute lung injury, asthma and inhaled toxicants. Because the ?eld is always evolving, each chapter includes recommended readings that lead the reader to sources of additional information, such as the review on remodeling of the blood gas barrier by West and Mathieu-Costello.
Physiology And Pharmacology Of The Airways
DOWNLOAD
Author : Jay A. Nadel
language : en
Publisher:
Release Date : 1980
Physiology And Pharmacology Of The Airways written by Jay A. Nadel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Airway (Medicine) categories.
An Introduction To Smooth Muscle Mechanics 2nd Edition
DOWNLOAD
Author : Chun Y. Seow
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2020-11-13
An Introduction To Smooth Muscle Mechanics 2nd Edition written by Chun Y. Seow and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-13 with Medical categories.
This second edition is an updated version of an introductory level textbook intended for students who are interested in understanding the mechanical properties of smooth muscle. Compared with skeletal and cardiac muscles, smooth muscle is the least understood in terms of its contraction mechanism and the structure of its contractile apparatus. Nevertheless, it is an important tissue that is vital in many organ functions, such as blood pressure control, intestinal peristalsis, and the emptying of the bladder. Dysfunction of the muscle has been implicated in many diseases such as high blood pressure, asthma, and overactive bladders. This is the only book-length treatment of functional models of a variety of smooth muscle behaviors with their corresponding mathematical descriptions, and offers an easy-to-follow, step-by-step mathematical derivation that will help students to appreciate the muscle cell as a fine-tuned aggregate of mechanisms governed by the fundamental laws of physics. In addition to providing a detailed description of the known subcellular structure and mechanical function of the contractile apparatus of smooth muscle, it also covers experimentation techniques, instrumentation, and data analysis. The book is a must-have information source for anyone interested in smooth muscle cell ultrastructure, physiology, biochemistry, and pharmacology.