Smooth Muscle Spontaneous Activity
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Smooth Muscle Spontaneous Activity
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Author : Hikaru Hashitani
language : en
Publisher: Springer
Release Date : 2019-06-10
Smooth Muscle Spontaneous Activity written by Hikaru Hashitani and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-10 with Medical categories.
This book presents the commonality and heterogeneity of the mechanisms underlying smooth muscle spontaneous activity in various smooth muscle organs and in addition discusses their malfunctions in disease and their potential as novel therapeutic targets. To facilitate understanding, the volume is divided into five parts and covers 16 organs: airways, gastrointestinal tract (phasic muscle, tonic muscle), renal pelvis, ureter, urinary bladder, urethra, corporal tissue, prostate, uterus, oviducts, seminal vesicle, artery, vein, microvasculature, and lymphatic vessels. This structure will help readers to comprehend the most up-to-date information on the similarities and differences in the contractile mechanisms driving various smooth muscles as well as their potential manipulations in particular visceral organ pathologies. The vast advancements in gene, electrical recording, and imaging technologies in this field are also discussed, with review of past achievements and consideration of likely future developments. This book will be of worldwide interest to clinicians, students, and researchers alike.
Smooth Muscle Spontaneous Activity
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Author : Hikaru Hashitani
language : en
Publisher:
Release Date : 2019
Smooth Muscle Spontaneous Activity written by Hikaru Hashitani and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Human physiology categories.
This book presents the commonality and heterogeneity of the mechanisms underlying smooth muscle spontaneous activity in various smooth muscle organs and in addition discusses their malfunctions in disease and their potential as novel therapeutic targets. To facilitate understanding, the volume is divided into five parts and covers 16 organs: airways, phasic muscle, tonic muscle, renal pelvis, ureter, urinary bladder, urethra, corporal tissue, prostate, uterus, oviducts, seminal vesicle, artery, vein, microvasculature, and lymphatic vessels. This structure will help readers to comprehend the most up-to-date information on the similarities and differences in the contractile mechanisms driving various smooth muscles as well as their potential manipulations in particular visceral organ pathologies. The vast advancements in gene, electrical recording, and imaging technologies in this field are also discussed, with review of past achievements and consideration of likely future developments. This book will be of worldwide interest to clinicians, students, and researchers alike.
Smooth Muscle
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Author : Edith Bülbring
language : en
Publisher: Hodder Education
Release Date : 1970
Smooth Muscle written by Edith Bülbring and has been published by Hodder Education this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with Science categories.
Extracellular Osmolality And Vascular Smooth Muscle Activity
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Author : Olof Jonsson
language : en
Publisher:
Release Date : 1970
Extracellular Osmolality And Vascular Smooth Muscle Activity written by Olof Jonsson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with Osmoregulation categories.
Pharmacology Of Smooth Muscle Ed By Edith Bulbring 1962
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Author :
language : en
Publisher:
Release Date : 1964
Pharmacology Of Smooth Muscle Ed By Edith Bulbring 1962 written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1964 with categories.
Colonic Motility
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Author : Sushil K. Sarna
language : en
Publisher: Biota Publishing
Release Date : 2010-11-01
Colonic Motility written by Sushil K. Sarna and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-01 with Medical categories.
Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.
Keynes Aidley S Nerve And Muscle
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Author : Christopher L.-H. Huang
language : en
Publisher: Cambridge University Press
Release Date : 2020-11-19
Keynes Aidley S Nerve And Muscle written by Christopher L.-H. Huang and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-19 with Medical categories.
Editions previous to this one had R.D. Keynes and David J. Aidley as primary and secondary authors.
Pharmacology Of Smooth Muscle Edited By Edith B Lbring
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Author : Helena Rašková
language : en
Publisher:
Release Date : 1964
Pharmacology Of Smooth Muscle Edited By Edith B Lbring written by Helena Rašková and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1964 with Pharmacology categories.
Calcium Channel Activity And Force Regulation In Smooth Muscle
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Author : Maria Gomez
language : en
Publisher:
Release Date : 1998
Calcium Channel Activity And Force Regulation In Smooth Muscle written by Maria Gomez and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Calcium channels categories.
Airways Smooth Muscle Development And Regulation Of Contractility
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Author : David Raeburn
language : en
Publisher: Birkhäuser
Release Date : 2013-03-08
Airways Smooth Muscle Development And Regulation Of Contractility written by David Raeburn and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-08 with Medical categories.
Most studies on autonomic innervation of smooth muscle have focused on the short-term mechanisms involved in neurotransmission in physiological and pathophysiological conditions. However recent obser vations of the long-term plasticity of this system, i. e. its capacity for regeneration and for compensatory change in pattern of innervation and expression of cotransmitters and receptors in ageing, following surgery, trauma or in disease, have indicated that an understanding of the mechanisms involved could influence the design of therapeutic regimes. There is increasing evidence for long-term communication between nerves and smooth muscle cells during development and throughout adult life. To date, the trophic interactions between nerves and airway musculature have attracted little interest, consequently, much of the information presented here is drawn from studies using other smooth muscles. However, the questions posed about trophic interactions dur ing development apply as much to airways smooth muscle neuroeffector systems as to other autonomic neuroeffector systems. These are: i) How do developing nerve fibres know where to go and how do they reach their target sites? ii) What determines the density and pattern of inner vation at reaching the effector? iii) How do the nerves survive and maintain their position once established? iv) What factors influence neurochemical differentiation such that genetically multipotential neu rones are triggered to synthesize one or combinations of neurotransmit ters? v) What influence do nerves have on the structure, function and receptor expression of their effector cells? vi) How do diseases interrupt these processes? - see [1].