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Albumin In Medicine


Albumin In Medicine
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Albumin In Medicine


Albumin In Medicine
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Author : Masaki Otagiri
language : en
Publisher: Springer
Release Date : 2016-11-01

Albumin In Medicine written by Masaki Otagiri and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-01 with Medical categories.


This book presents a comprehensive overview of medical and pharmaceutical applications of human serum albumin (HSA), with updates on structural aspects of albumin from the perspectives of X-ray crystallography and NMR, endogenous and exogenous ligand binding of albumin in various pathological conditions, and genetic variants and their phenotypes. Rapid progress and development of its applications have resulted in outstanding results for which albumin has clearly been proven to be a robust biomaterial. Contributions from leading international experts in this field show how HSA is applied to diagnosis, therapy, drugs, and treatment, with a comprehensive introduction of HSA. This volume will appeal to scientists in pharmaceutical and medical research including pharmaceutical chemists, pharmacokineticists, toxicologists, and biochemists not only in academia but also in industry. Readers can effectively acquire the most recent knowledge of applications of HSA and its impact on human health in a single volume.



All About Albumin


All About Albumin
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Author : Theodore Peters Jr.
language : en
Publisher: Academic Press
Release Date : 1995-12-21

All About Albumin written by Theodore Peters Jr. and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-12-21 with Science categories.


The first of its kind, All About Albumin summarizes the chemistry, genetics, metabolism, clinical implications, and commercial aspects of albumin. It provides the most up-to-date sequences, structures, and compositions of many species, and includes more than 2000 references. Includes up-to-date sequences, structures, and compositions of many species Reviews the protein chemistry, genetic control, and metabolism of albumin Covers medical and cell culture applications in vivo and in vitro, with a section on handling albumin in the laboratory Presents the relationship of albumin to its superfamily with an updated scheme for their evolution First complete coverage of all aspects of serum albumin in one volume, with more than 2000 references



Clinical Aspects Of Albumin


Clinical Aspects Of Albumin
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Author : S.H. Yap
language : en
Publisher: Springer
Release Date : 2011-12-14

Clinical Aspects Of Albumin written by S.H. Yap and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-14 with Medical categories.


Albumin is the most abundant serum protein produced by the liver. In clinical practice the serum level of albumin continues to be used as an important marker of the presence, progress or ofthe improvement of many diseases, even though it is the complex end result of synthesis, degradation a. nd distribution between intra- and extravascular space. The clinical history of albumin began as early as in 1837, when Ancell first recognized "albumen" and noted that this protein is needed for trans port functions, for maintaining fluidity of the vascular system and for the prevention of edema. However, the important physiological properties of serum proteins and their role in the regulation ofthe oncotic pressure were demonstrated later by the physiologist E. H. Starling in 1895. In 1917 the clinician A. A. Epstein first described the edema in patients with the nephro tic syndrome as being a result of a very low level of serum albumin. Al though the determination of serum albumin concentration became more popular after Howe in 1921 introduced the technique of separation of serum globulins from albumin by sodium sulfate, the first preparations of human serum albumin were made available for clinical use in only 1941 by the development of plasma fractionation by Cohn and his coworkers at Harvard Medical School.



Transactions Of The Section On Practice Of Medicine Of The American Medical Association


Transactions Of The Section On Practice Of Medicine Of The American Medical Association
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Author :
language : en
Publisher:
Release Date : 1905

Transactions Of The Section On Practice Of Medicine Of The American Medical Association written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1905 with categories.




Albumin Based Drug Delivery Systems


Albumin Based Drug Delivery Systems
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Author : Gábor Katona
language : en
Publisher:
Release Date : 2022

Albumin Based Drug Delivery Systems written by Gábor Katona and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.


Albumin is playing an increasing role as a versatile, biodegradable drug carrier in clinical theranostics. By applying different techniques, smart drug-delivery systems can be developed from albumin in order to improve drug delivery of different active pharmaceutical ingredients, even small-molecule drugs, peptides or enzymes. Principally, three drug delivery technologies can be distinguished for binding small-molecule or peptide drugs through the charged amino acids, carboxyl, and amino groups of albumin: physical or covalent binding of the drug to albumin through a ligand- or protein-binding group, the fusion of drug with albumin or the encapsulation of drugs into albumin nanoparticles. The accumulation of albumin in inflamed tissues and solid tumours forms the rationale for developing albumin-based drug delivery systems for targeted drug delivery. Besides tumour therapy, albumin-based drug delivery systems can be successfully applied as anti-inflammatory and anti-thrombotic coating for medical devices. The development and optimization of albumin nanoparticles may also be a rational and promising tool for conventional or alternative administration routes in order to improve therapy. This collection provides an overview of the significant scientific research works in this field, which may inspire researchers towards further development and utilization of these smart drug delivery systems.



Albumin Based Drug Delivery Systems


Albumin Based Drug Delivery Systems
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Author : Gabor Katona
language : en
Publisher:
Release Date : 2022-05-03

Albumin Based Drug Delivery Systems written by Gabor Katona and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-03 with categories.


Albumin is playing an increasing role as a versatile, biodegradable drug carrier in clinical theranostics. By applying different techniques, smart drug-delivery systems can be developed from albumin in order to improve drug delivery of different active pharmaceutical ingredients, even small-molecule drugs, peptides or enzymes. Principally, three drug delivery technologies can be distinguished for binding small-molecule or peptide drugs through the charged amino acids, carboxyl, and amino groups of albumin: physical or covalent binding of the drug to albumin through a ligand- or protein-binding group, the fusion of drug with albumin or the encapsulation of drugs into albumin nanoparticles. The accumulation of albumin in inflamed tissues and solid tumours forms the rationale for developing albumin-based drug delivery systems for targeted drug delivery. Besides tumour therapy, albumin-based drug delivery systems can be successfully applied as anti-inflammatory and anti-thrombotic coating for medical devices. The development and optimization of albumin nanoparticles may also be a rational and promising tool for conventional or alternative administration routes in order to improve therapy. This collection provides an overview of the significant scientific research works in this field, which may inspire researchers towards further development and utilization of these smart drug delivery systems.



Cooperation Of Liver Cells In Health And Disease


Cooperation Of Liver Cells In Health And Disease
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Author : Z. Kmiec
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Cooperation Of Liver Cells In Health And Disease written by Z. Kmiec and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.


It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.



Transactions Of The College Of Physicians Of Philadelphia


Transactions Of The College Of Physicians Of Philadelphia
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Author : College of Physicians of Philadelphia
language : en
Publisher:
Release Date : 1894

Transactions Of The College Of Physicians Of Philadelphia written by College of Physicians of Philadelphia and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1894 with Medicine categories.




Monitoring And Intervention For The Critically Ill Small Animal


Monitoring And Intervention For The Critically Ill Small Animal
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Author : Rebecca Kirby
language : en
Publisher: John Wiley & Sons
Release Date : 2016-12-19

Monitoring And Intervention For The Critically Ill Small Animal written by Rebecca Kirby and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-19 with Medical categories.


Monitoring and Intervention for the Critically Ill Small Animal: The Rule of 20 offers guidance for assessing the patient, interpreting diagnostic test results, and selecting appropriate monitoring procedures. Based on Rebecca Kirby’s time-tested Rule of 20, with a chapter devoted to each item on the checklist Provides comprehensive guidance for monitoring a critically ill small animal patient Emphasizes the interplay of each parameter with one another Designed for fast access on the clinic floor, with potentially life-saving ideas, tips, lists and procedures Presents tables, schematics, algorithms, and drawings for quick reference



Clinical Methods


Clinical Methods
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Author : Henry Kenneth Walker
language : en
Publisher: Butterworth-Heinemann
Release Date : 1990

Clinical Methods written by Henry Kenneth Walker and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medical categories.


A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR