Albumin Based Drug Delivery Systems
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Albumin Based Drug Delivery Systems
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Author : Gabor Katona
language : en
Publisher:
Release Date : 2022-05-03
Albumin Based Drug Delivery Systems written by Gabor Katona and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-03 with categories.
Albumin is playing an increasing role as a versatile, biodegradable drug carrier in clinical theranostics. By applying different techniques, smart drug-delivery systems can be developed from albumin in order to improve drug delivery of different active pharmaceutical ingredients, even small-molecule drugs, peptides or enzymes. Principally, three drug delivery technologies can be distinguished for binding small-molecule or peptide drugs through the charged amino acids, carboxyl, and amino groups of albumin: physical or covalent binding of the drug to albumin through a ligand- or protein-binding group, the fusion of drug with albumin or the encapsulation of drugs into albumin nanoparticles. The accumulation of albumin in inflamed tissues and solid tumours forms the rationale for developing albumin-based drug delivery systems for targeted drug delivery. Besides tumour therapy, albumin-based drug delivery systems can be successfully applied as anti-inflammatory and anti-thrombotic coating for medical devices. The development and optimization of albumin nanoparticles may also be a rational and promising tool for conventional or alternative administration routes in order to improve therapy. This collection provides an overview of the significant scientific research works in this field, which may inspire researchers towards further development and utilization of these smart drug delivery systems.
Albumin Based Drug Delivery Systems
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Author : Gábor Katona
language : en
Publisher:
Release Date : 2022
Albumin Based Drug Delivery Systems written by Gábor Katona and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.
Albumin is playing an increasing role as a versatile, biodegradable drug carrier in clinical theranostics. By applying different techniques, smart drug-delivery systems can be developed from albumin in order to improve drug delivery of different active pharmaceutical ingredients, even small-molecule drugs, peptides or enzymes. Principally, three drug delivery technologies can be distinguished for binding small-molecule or peptide drugs through the charged amino acids, carboxyl, and amino groups of albumin: physical or covalent binding of the drug to albumin through a ligand- or protein-binding group, the fusion of drug with albumin or the encapsulation of drugs into albumin nanoparticles. The accumulation of albumin in inflamed tissues and solid tumours forms the rationale for developing albumin-based drug delivery systems for targeted drug delivery. Besides tumour therapy, albumin-based drug delivery systems can be successfully applied as anti-inflammatory and anti-thrombotic coating for medical devices. The development and optimization of albumin nanoparticles may also be a rational and promising tool for conventional or alternative administration routes in order to improve therapy. This collection provides an overview of the significant scientific research works in this field, which may inspire researchers towards further development and utilization of these smart drug delivery systems.
Drug Delivery Systems
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Author : Kewal K. Jain
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-03-07
Drug Delivery Systems written by Kewal K. Jain and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-07 with Science categories.
In this concise and systematic book, a team of experts select the most important, cutting-edge technologies used in drug delivery systems. They take into account significant drugs, new technologies such as nanoparticles, and therapeutic applications. The chapters present step-by-step laboratory protocols following the highly successful Methods in Molecular BiologyTM series format, offering readily reproducible results vital for pharmaceutical physicians and scientists.
Human Serum Albumin Hsa
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Author : Travis Stokes
language : en
Publisher:
Release Date : 2015
Human Serum Albumin Hsa written by Travis Stokes and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with SCIENCE categories.
Human Serum Albumin (HSA) is the most abundant plasma protein. It has been widely used for drug delivery systems and has recently emerged as a versatile carrier for therapeutic agents against diabetes, cancer and infectious diseases. This book provides an overview of the expanding field of preclinical and clinical applications and developments that use albumin as a carrier of drug delivery systems. The authors' discuss the properties of drug binding sites within the structure of HSA, discuss new possibilities for the therapeutic potential of HSA and analyze recently reported HSA-drug complexes including HSA-antibody conjugates. Novel investigations on the applications of albumin fusion proteins are discussed as well, with a focus on tumor targeting and intracellular delivery. Other chapters examine the different aspects of albumin glycation and oxidation, the changes in the structure of human serum albumin determined from infrared spectroscopy and a review of CAPIDAN, a special fluorescent dye, which attaches to drug binding sites of human serum albumin.
Silk Based Drug Delivery Systems
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Author : Elia Bari
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-10-07
Silk Based Drug Delivery Systems written by Elia Bari and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-07 with Science categories.
Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin.
Recent Advances In Drug Delivery Systems
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Author : James M. Anderson
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Recent Advances In Drug Delivery Systems written by James M. Anderson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The evident rapid expansion of scientific work and intense interest in both experimental and clinical aspects of new drug delivery systems provided strong motivation for planning this symposium. In designing the program, speakers were identified for their particular expertise in a wide range of topics such as dermal delivery systems, pro-drugs, oral prolonged release, rate-controlled drug delivery, the pharmacokinetics of drug release systems, the synthesis of polymeric drug carriers and the refinement of drug delivery pumps. Because of the considerable involvement of diverse scientists from laboratories around the world where investigations relevant to the topic are now being pursued, a deliberate effort was made to invite international leaders in the field to share their knowledge and experimental outcomes. Thus, plenary papers and panel discussions were offered by organic chemists, bioengineers, patholo gists, material scientists, physical chemists, and pharmacokineti cists from academic and industrial laboratories in some dozen countries. This book which records the presentations offered at the sym posium covers a broad array of topics ranging from general overviews of the physicochemical concepts and analytical methodology which underpin the refinement of drug delivery systems and the tissue responses associated with the use of such systems through detailed discussions of a variety of current approaches employed in the development of new systems.
Polymers In Controlled Drug Delivery
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Author : Lisbeth Illum
language : en
Publisher: Butterworth-Heinemann
Release Date : 1987
Polymers In Controlled Drug Delivery written by Lisbeth Illum and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.
Albumin In Medicine
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Author : Masaki Otagiri
language : en
Publisher: Springer
Release Date : 2016-11-01
Albumin In Medicine written by Masaki Otagiri and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-01 with Medical categories.
This book presents a comprehensive overview of medical and pharmaceutical applications of human serum albumin (HSA), with updates on structural aspects of albumin from the perspectives of X-ray crystallography and NMR, endogenous and exogenous ligand binding of albumin in various pathological conditions, and genetic variants and their phenotypes. Rapid progress and development of its applications have resulted in outstanding results for which albumin has clearly been proven to be a robust biomaterial. Contributions from leading international experts in this field show how HSA is applied to diagnosis, therapy, drugs, and treatment, with a comprehensive introduction of HSA. This volume will appeal to scientists in pharmaceutical and medical research including pharmaceutical chemists, pharmacokineticists, toxicologists, and biochemists not only in academia but also in industry. Readers can effectively acquire the most recent knowledge of applications of HSA and its impact on human health in a single volume.
Protein And Peptide Nanoparticles For Drug Delivery
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-03-26
Protein And Peptide Nanoparticles For Drug Delivery written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-26 with Science categories.
Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in application of powerful techniques in a wide bioscience area Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables
Colloidal Drug Delivery Systems
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Author : Jorg Kreuter
language : en
Publisher: CRC Press
Release Date : 2014-07-22
Colloidal Drug Delivery Systems written by Jorg Kreuter and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-22 with Science categories.
This volume provides a single-source of reviews for all the important colloidal drug delivery systems, including nanoparticles, liposomes, niosomes, microemulsions and ointments. Over 1000 bibliographic citations, as well as tables, drawings, equations and photographs, are provided. Arranged in order of increasing physical complexity, this work ana
