Silk Based Drug Delivery Systems
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Silk Based Drug Delivery Systems
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Author : Elia Bari
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-10-05
Silk Based Drug Delivery Systems written by Elia Bari and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-05 with Technology & Engineering categories.
Silk proteins show excellent biocompatibility, controllable biodegradability and non-immunogenicity, and as such are studied extensively worldwide for biomedical applications. In particular, there is increasing interest in their use for drug delivery systems. This focussed book on silk proteins for drug delivery systems, delves into a key emerging area to outline the concepts and define the field. Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin. Showing how these proteins are employed in micro and nano drug delivery systems, their use in pre-clinical and clinical trials, and closing with chapter on sustainability- driven innovation in the pharma industry, this book is ideal for graduates and researchers in biomaterials science and pharmaceutical science.
Functional Biomaterials
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Author : Sougata Jana
language : en
Publisher: Springer Nature
Release Date : 2022-03-29
Functional Biomaterials written by Sougata Jana and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-29 with Science categories.
This book explores in depth a wide range of functional biomaterials-based systems for drug, gene delivery, and biomedical aspects. The chapters cover newer technologies such as polymeric micelle, pH-responsive biomaterials, stimuli-responsive hydrogels, silk fibroin, inorganic biomaterials, synthetic biomaterials, 3D printed biomaterials, metallic biomaterials, ceramic and hybrid biomaterials. It also describes the theranostic approaches for cancer therapy, the biomaterials-based nanofibers scaffolds in tissue engineering, as well as the strategies applications of metallic biomaterials for the medical and dental prosthetic field. This newer and updated approach will be attractive for biomedical engineering students working on materials science in the development of novel drug delivery strategies. The book will be an important reference for researchers and professionals working on biomaterial research in the pharmaceutical and medical fields.
Drug Delivery Systems
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Author : Stroeve Pieter
language : en
Publisher: World Scientific
Release Date : 2017-11-27
Drug Delivery Systems written by Stroeve Pieter and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-27 with Technology & Engineering categories.
With the alarming increase in cancer diagnoses and genetic illnesses, traditional drug agents and their delivery media need to be re-evaluated to address a quickly evolving field. With newer smart materials for the controlled release of macromolecules, peptides, genetic material, etc. further complications arise, such as material performance, synthesis, functionalization and targeting, biological identity, and biocompatibility. The book provides a comprehensive overview of the recent developments on "smart" targeting and drug delivery systems with a variety of carriers like nanoparticles, membranes, and hydrogels. It contains detailed descriptions on the recent trends in this field in the ongoing battle with catastrophic diseases like cancer. This field of research has been in its infancy and continues to face growth, and with it, further challenges and difficulties along the way toward maturity, which are accurately introduced in this book. Contents: Drug Delivery Systems: Possibilities and Challenges (Ryan Spitler, Saeid Zanganeh, Tahereh Jafari, Nasser Khakpash, Mohsen Erfanzadeh, Jim Q Ho, and Nastaran Sakhaie)Nanoparticles in Circulation: Blood Stability (Saeid Zanganeh, Tahereh Jafari, Nasser Khakpash, Mohsen Erfanzadeh, and Jim Q Ho)How do Nanoparticles (NPs) Pass Barriers? (Saeid Zanganeh, Ryan Spitler, Najme Javdani, and Jim Q Ho)Gated Porous Materials for Biomedical Application (Félix Sancenón, Erick Yu, Elena Aznar, M Dolores Marcos, and Ramón Martínez-Máñez)Controlled Release from Iron Oxide Nanoparticles (Masoud Rahman)The Reverse of Controlled Release: Controlled Sequestration of Species and Biotoxins into Nanoparticles (NPs) (Jenifer Gómez-Pastora, Eugenio Bringas, María Lázaro-Díez, José Ramos-Vivas, and Inmaculada Ortiz)Membranes for Controlled Release (Vida Araban, Neda Aslankoohi, and Mohammad Raoufi)Controlled Released from Hydrogel (Hossein Riahinezhad, Vida Araban, and Mohammad Raoufi)Nano Delivery Systems (Sophie Laurent, Afsaneh Lahooti, Saeed Shanehsazzadeh, and Robert N Muller)Legal Framework for Protection of Pharmaceutical Trade Marks in Europe and USA (Mohammad Hossein Erfanmanesh, and Shirin Sharifzadeh)Future Perspective on the Smart Delivery of Biomolecules (Erick Yu, Félix Sancenón, Elena Aznar, Ramón Martínez-Máñez, María Dolores Marcos, Mohammad J Hajipour, Morteza Mahmoudi, and Pieter Stroeve) Readership: Nanotechnologists; biomedical engineers; chemical engineers; materials scientists; biotechnology researchers; chemists; biological scientists; cell physiologists; medical scientists; gene therapists. Keywords: Drug Delivery Systems;Nanoparticles;Biomaterials;TargetingReview: Key Features: Comprehensive overview on "smart" targeting and drug delivery systemsUnderstanding of the biological identity of nanoparticles for drug delivery applicationsDetailed information on the legal framework for protection of pharmaceutical trade mark in Europe and the United States
Polymeric Drugs And Drug Delivery Systems
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Author : Raphael M. Ottenbrite
language : en
Publisher: CRC Press
Release Date : 2019-04-30
Polymeric Drugs And Drug Delivery Systems written by Raphael M. Ottenbrite and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-30 with Science categories.
Polymeric materials are now playing an increasingly important role in pharmaceuticals, as well as in sensing devices, in situ prostheses and probes, and microparticle diagnostic agents. This new volume consists of twenty-two recent research-based reports on the developments in these areas of pharmaceutical and biomaterials technology. The reports w
Molecularly Imprinted Polymers As Advanced Drug Delivery Systems
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Author : Zhaosheng Liu
language : en
Publisher: Springer Nature
Release Date : 2021-04-23
Molecularly Imprinted Polymers As Advanced Drug Delivery Systems written by Zhaosheng Liu and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-23 with Medical categories.
This book summarizes the recent advancements for drug delivery systems (DDS) in terms of fundamental principles, rapidly emerging techniques and developing frontiers of molecular imprinting. Especially with the combination of enantioselective molecularly imprinted polymers and water compatible molecularly imprinted polymers, stimuli responsive imprinted DDS have been innovated and applied to dermal delivery, ophthalmic drugs and cancer treatment. This philosophy comprehensively revolutionizes the treatment strategy of human healthcare and provides the possibility to re-trigger in vivo an exhaust system after the complete release of the starting drug cargo, thus enabling precision medicine. To this end, the following unique features will be discussed and concluded: 1) State-of-the-art definition of MIP as drug delivery systems. 2) Advanced techniques and clinical applications of MIP as drug delivery systems in the past decade. 3) Novel frontiers and brand-new technologies, for example, drug delivery devices for zero-order sustained release and stimuli responsive imprinted DDS. 4) Revolutionary impact on dermal delivery, ophthalmic drugs and cancer treatment. 5) Future challenges and perspectives
Advanced Drug Delivery
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Author : Ashim Mitra
language : en
Publisher: John Wiley & Sons
Release Date : 2013-08-26
Advanced Drug Delivery written by Ashim Mitra and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-26 with Medical categories.
Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.
Liposome Based Drug Delivery Systems
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Author : Wan-Liang Lu
language : en
Publisher: Springer
Release Date : 2021-07-01
Liposome Based Drug Delivery Systems written by Wan-Liang Lu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-01 with Technology & Engineering categories.
This volume describes the protocols for fabrication of liposomal drug delivery system, and consists of two parts. The first part emphasizes the basic protocols and concepts for fabrication of drug-loaded liposomes. For new investigators, laying the groundwork is the first step. This part focuses on the fabrication details in liposomes formulations, which are the so-called small tricks while usually not disclosed in mostly published research articles. However, these processing details are crucial for the preparation of liposomes. And the second part focuses on the strategies in modified and/or functionalized liposomes to adapt to pathophysiological environment, as well as their application in treating diseases. As new analytical and synthetic technologies become available, and improved understanding of pathophysiology, various functionalized drug liposomes are developing to fit the requirements of different therapeutic purposes, exhibiting a broad range of applications. Accordingly, the objectives of this part are aimed at deeply unearthing the formulation of drug-loaded liposomes, describing the detailed operation of liposomal formulation, and further demonstrating their potential applications. Therefore, this volume shows the features of experimental report or protocol for proving a guide to scientists, research students, and young investigators in pharmaceutical enterprises.
Antibody Mediated Drug Delivery Systems
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Author : Yashwant V. Pathak
language : en
Publisher: John Wiley & Sons
Release Date : 2012-04-17
Antibody Mediated Drug Delivery Systems written by Yashwant V. Pathak and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-17 with Science categories.
This book covers various aspects of antibody mediated drug delivery systems – theoretical aspects, processing, viral and non-viral vectors, and fields where these systems find and /or are being evaluated for applications as therapeutics and diagnostic treatment. Chapters discuss actual applications of techniques used for formulation and characterization. Applications areas include cancer, pulmonary, ocular diseases; brain drug delivery; and vaccine delivery. The contributing authors represent over 10 different countries, covering recent developments happening around the globe.
Hydrogels
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Author : Thakur Raghu Raj Singh
language : en
Publisher: CRC Press
Release Date : 2018-02-28
Hydrogels written by Thakur Raghu Raj Singh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-28 with Medical categories.
Hydrogels are crosslinked, macromolecular polymeric materials arranged in a three-dimensional network, which can absorb and retain large amounts of water. Hydrogels are commonly used in clinical practice and experimental medicine for a wide range of applications, including drug delivery, tissue engineering and regenerative medicine, diagnostics, cellular immobilization, separation of biomolecules or cells, and barrier materials to regulate biological adhesions. This book elucidates the underlying concepts and emerging applications of hydrogels and will provide key case studies and critical analysis of the existing research.
Drug Delivery Systems In Cancer Therapy
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Author : Dennis M. Brown
language : en
Publisher: Springer Science & Business Media
Release Date : 2004
Drug Delivery Systems In Cancer Therapy written by Dennis M. Brown and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.
A major difficulty in successfully treating cancer with drugs is achieving adequate drug concentrations in the diseased areas without overexposing drug-sensitive normal tissues. In a number of cases, specialized drug delivery systems are required to realize a therapeutic gain. In Drug Delivery Systems in Cancer Therapy, Dennis M. Brown has assembled a panel of leading experts to survey all the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. They also profile the use of novel formulation technologies-including synthetic polymers and biomaterials for sustained drug release to achieve greater therapeutic effect-that have demonstrated efficacy in a number of approved and late-stage clinical products. They also consider the benefits of, and future opportunities for, various drug delivery systems, as well as the experimental techniques used in their evaluation. Although the focus is primarily on small molecule delivery, many of the technologies described can also be effective in delivering larger biomolecules. Comprehensive, cutting-edge, and highly practical, Drug Delivery Systems in Cancer Therapy captures for experimental oncologists, medicinal chemists, and pharmacologists the universe of approaches, technologies, and systems available for substantially enhancing the therapeutic outcome of anticancer drug delivery today.