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Protein And Peptide Nanoparticles For Drug Delivery


Protein And Peptide Nanoparticles For Drug Delivery
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Protein And Peptide Nanoparticles For Drug Delivery


Protein And Peptide Nanoparticles For Drug Delivery
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-03-26

Protein And Peptide Nanoparticles For Drug Delivery written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-26 with Science categories.


Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in application of powerful techniques in a wide bioscience area Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables



Peptide And Protein Delivery


Peptide And Protein Delivery
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Author : Chris Van Der Walle
language : en
Publisher: Academic Press
Release Date : 2011-05-12

Peptide And Protein Delivery written by Chris Van Der Walle and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-12 with Science categories.


The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. A needed reference for entry level researchers and researchers working in interdisciplinary / collaborative projects, Peptide and Protein Delivery addresses the current and emerging routes for delivery of therapeutics. Covering cerebral delivery, pulmonary delivery, transdermal delivery, intestinal delivery, ocular delivery, parenteral delivery, and nasal delivery, this resource offers an overview of the main routes in therapeutics. Researchers across biochemistry, pharmaceutical, molecular biology, cell biology, immunology, chemistry and biotechnology fields will find this publication invaluable for peptide and protein laboratory research. Discusses the most recent data, ideas and concepts Presents case studies and an industrial perspective Details information from the molecular level to bioprocessing Thought provoking, for the novice to the specialist Timely, for today's biopharmaceuticals market



Nanotechnology In Drug Delivery


Nanotechnology In Drug Delivery
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Author : Saurabh Bhatia
language : en
Publisher: CRC Press
Release Date : 2017-03-03

Nanotechnology In Drug Delivery written by Saurabh Bhatia and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-03 with Medical categories.


This important new book provides the fundamental understanding of the peptide and protein drug delivery systems with a special focus on their nanotechnology applications. Addressing an increasing interest in peptide and protein drug delivery systems in both academic and industrial circles worldwide, this book fills the need for a comprehensive review and assessment of conventional and nonconventional routes of administration.



Protein And Peptide Drug Delivery


Protein And Peptide Drug Delivery
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Author : Nitai Charan Giri
language : en
Publisher:
Release Date : 2020

Protein And Peptide Drug Delivery written by Nitai Charan Giri and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Medical categories.


Protein and peptide-based drugs have great potential applications as therapeutic agents since they have higher efficacy and lower toxicity than chemical drugs. However, difficulty with their delivery has limited their use. In particular, their oral bioavailability is very low, and the transdermal delivery faces absorption limitations. Therefore, most of the protein and peptide-based drugs are administered by the parenteral route. However, this route also has some problems, such as patient discomfort, especially for pediatric use. Extensive research has been performed over the past few decades to develop protein and peptide delivery systems that circumvent the problems mentioned above. Various strategies that have been employed during this time include nanoparticle carriers, absorption enhancers, enzyme inhibitors, mucoadhesive polymers, and chemical modification of protein or peptide structures. However, most of these strategies are focused on the delivery of proteins or peptides via the oral route since it is the most preferred route considering its high level of patient acceptance, long-term compliance, and simplicity. However, other routes of administration such as transdermal, nasal, pulmonary can also be attractive alternatives for protein and peptide delivery. This chapter will discuss the most effective approaches used to develop protein and peptide drug delivery systems.



Peptide And Protein Drug Delivery


Peptide And Protein Drug Delivery
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Author : Vincent Lee
language : en
Publisher: CRC Press
Release Date : 1990-11-19

Peptide And Protein Drug Delivery written by Vincent Lee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-11-19 with Science categories.


This reference/text covers fundamentals of peptide and protein drug delivery, including such considerations as synthesis, physical chemistry and biochemistry, analysis, proteolytic and transport constraints, pharmacokinetics, and pharmacodynamics; bioavailability from routes of administration, detai



Delivery Of Protein And Peptide Drugs In Cancer


Delivery Of Protein And Peptide Drugs In Cancer
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Author : Vladimir P Torchilin
language : en
Publisher: World Scientific
Release Date : 2006-04-05

Delivery Of Protein And Peptide Drugs In Cancer written by Vladimir P Torchilin and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-05 with Medical categories.


Written by leading scientists in the field of delivery of protein and peptide drugs to tumors for cancer therapy, this important book provides a broad introduction to the field, with discussion by key experts on the physiological barriers for protein and peptide drugs in tumors, and the different approaches to stabilization of these drugs in biological surroundings, as well as their enhanced delivery to tumors and inside cancer cells.This book can be used as an advanced textbook by graduate students and young scientists and clinicians at the early stages of their career. It is also suitable for non-experts from related areas of chemistry, biochemistry, molecular biology, physiology, experimental and clinical oncology and pharmaceutical sciences, who are interested in general problems of drug delivery and drug targeting as well as in a more specialized topics of using protein and peptide drugs for tumor therapy.Prof Torchilin is an expert in Nanomedicine and a recipient of numerous awards including the Lenin Prize in Science & Technology of the former USSR, membership in the European Academy of Sciences, and AAPS Research Achievement Award in Pharmaceutics and Drug Delivery. He served as an Associate Professor of Radiology at Harvard Medical School before joining Northeastern University as the Chairman of the Department of Pharmaceutical Sciences.



Delivery Technologies For Biopharmaceuticals


Delivery Technologies For Biopharmaceuticals
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Author : Lene Jorgensen
language : en
Publisher: John Wiley & Sons
Release Date : 2009-10-23

Delivery Technologies For Biopharmaceuticals written by Lene Jorgensen and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-23 with Science categories.


Advances in biotechnology have provided scientists with an increasing number of biopharmaceuticals such as novel peptide and protein drugs as well as nucleic acid based drugs for gene therapy. However, successful delivery of these biopharmaceuticals is a major challenge because their molecular properties lead to poor physical and chemical stability in the body and limited membrane permeability. Therefore researchers are developing a range of new delivery technologies and materials to enable these new drugs to be delivered intact to their target sites. Delivery Technologies for Biopharmaceuticals describes strategies to overcome the main barriers for successful delivery of therapeutic peptides, proteins, and nucleic acid-based drugs or vaccines related to the site of administration and the target site. Many of the approaches described are reported in formulations in current clinical trials as well as in marketed products. Contents include: challenges in delivery of biopharmaceuticals novel formulation approaches for peptide and protein injectables non-viral chemical vectors and viral technology for delivery of nucleic acid based drugs immune response, adjuvants and delivery systems for vaccines several examples of delivery systems for different biopharmaceuticals a critical assessment of delivery technologies for biopharmaceuticals Delivery Technologies for Biopharmaceuticals is an essential single-volume introduction to the technologies used by researchers to ensure efficient delivery of this exciting new class of drugs. It will be of value to researchers and students working in drug delivery, formulation, biopharmaceuticals, medicinal chemistry, and new materials development.



Peptide And Protein Drug Delivery Using Polysaccharides


Peptide And Protein Drug Delivery Using Polysaccharides
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Author : Aakanchha Jain
language : en
Publisher: Elsevier
Release Date : 2023-10-10

Peptide And Protein Drug Delivery Using Polysaccharides written by Aakanchha Jain and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-10 with Science categories.


Peptide and Protein Drug Delivery Using Polysaccharides offers an interdisciplinary discussion of polysaccharides applied in peptide and protein drug delivery. Chapters consider basic biology of different polysaccharides of current interest and their production at pilot and large-scale stages by various techniques including, but not limited to, cell and hairy root cultures. Other sections examine factors affecting polysaccharide absorption, metabolism, and excretion in nascent, encapsulated, or conjugated forms, with unique coverage of vaccine absorption, metabolism, and drug delivery. A final section considers analytical methods for detection in tissue fluids and homogenates. Accessible figures, tables, and graphical abstracts are included throughout to support understanding. Specific polysaccharides discussed for therapeutic purposes include cellulose, hyaluronic acid, heparin, carageenan, alginic acid, agar and myrrh, acacia, tragacanth, ghatti gum, chitin, chitosan, starch, glycogen and dextran. Adopts an interdisciplinary approach across biochemistry, molecular biology, pharmaceutical sciences and drug delivery, and biotechnological perspectives Features accessible figures, tables and graphical abstracts across all chapters to support understanding Examines various polysaccharides of current interest and aspects affecting their absorption, metabolism, excretion and detection



Trends And Future Perspectives In Peptide And Protein Drug Delivery


Trends And Future Perspectives In Peptide And Protein Drug Delivery
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Author : Vincent Lee
language : en
Publisher: CRC Press
Release Date : 1995-02-01

Trends And Future Perspectives In Peptide And Protein Drug Delivery written by Vincent Lee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-02-01 with Medical categories.


First published in 1995. Routledge is an imprint of Taylor & Francis, an informa company.



Therapeutic Peptides And Proteins


Therapeutic Peptides And Proteins
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Author : Ajay K. Banga
language : en
Publisher: CRC Press
Release Date : 2015-04-23

Therapeutic Peptides And Proteins written by Ajay K. Banga and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-23 with Medical categories.


There are more than 500 biopharmaceuticals on the market, including more than 200 therapeutic proteins, making biologics the fastest growing sector in the biopharmaceutical market. These products include more than 40 monoclonal antibodies, for indications ranging from treatment or mitigation of various types of cancer to rheumatoid arthritis. The c