Aliphatic Polyester Nanoparticles For Drug Delivery Systems
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Aliphatic Polyester Nanoparticles For Drug Delivery Systems
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Author : Narumol Kreua-ongarjnukool
language : en
Publisher:
Release Date : 2019
Aliphatic Polyester Nanoparticles For Drug Delivery Systems written by Narumol Kreua-ongarjnukool and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Medical categories.
Drug delivery systems using aliphatic polyester nanoparticles are usually prepared via an emulsion process. These nanoparticles can control drug release and improve pharmacokinetics. Aliphatic polyesters are linear polymers containing ester linkages, showing sensitivity to hydrolytic degradation. The byproducts then promote autocatalytic degradation. These byproducts could enter the Krebs cycle and be eliminated from the body, resulting in the high biocompatibility of these nanoparticles. The properties of these polyesters are linked to the drug release rate due to biodegradation, i.e., polymer crystallinity, glass transition temperature, polymer hydrophobicity, and molecular weight (MW), all of which relatively influence hydrolysis. Mathematical equations have been used to study the factors and mechanisms that affect drug dissolution compared to experimental release data. The equations used as models for predicting the kinetics of drug release include the zero-order, first-order, Higuchi, Hixson-Crowell, and Korsmeyer-Peppas equations. Aliphatic polyester-based controlled drug delivery has surrounded much of the current activity in the estimation parameters of nanoparticles and stimulated additional research. Polymeric nanoparticles have potential in a wide range of applications, such as in biotechnology, vaccine systems, and the pharmaceutical industry. The main goal of this chapter is to discuss aliphatic polyester nanoparticles as drug carrier systems.
Handbook Of Polyester Drug Delivery Systems
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Author : M. N. V. Ravi Kumar
language : en
Publisher: CRC Press
Release Date : 2017-03-27
Handbook Of Polyester Drug Delivery Systems written by M. N. V. Ravi Kumar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-27 with Medical categories.
In the quest for innovative drug delivery systems attempting to meet the unmet needs in pharmaceutical space, research has taken a much more complicated path that poses a significant challenge for translation. Despite the progress made with novel materials, polyesters still remain at the helm of drug delivery technologies. This book provides a single source of reference of polyester drug delivery systems that covers a broad spectrum of materials design, manufacturing techniques, and applications.
Polymers In Nanomedicine
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Author : Shigeru Kunugi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-02-02
Polymers In Nanomedicine written by Shigeru Kunugi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-02 with Technology & Engineering categories.
Functional Polymer Conjugates for Medicinal Nucleic Acid Delivery, by Ernst Wagner Biodegradable Nanoparticles as Vaccine Adjuvants and Delivery Systems: Regulation of Immune Responses by Nanoparticle-Based Vaccine, by Takami Akagi, Masanori Baba and Mitsuru Akashi Biodegradable Polymeric Assemblies for Biomedical Materials, by Yuichi Ohya, Akihiro Takahashi and Koji Nagahama PEGylation Technology in Nanomedicine, by Yutaka Ikeda and Yukio Nagasaki Cytocompatible Hydrogel Composed of Phospholipid Polymers for Regulation of Cell Functions, by Kazuhiko Ishihara, Yan Xu and Tomohiro Konno Design of Biointerfaces for Regenerative Medicine, by Yusuke Arima, Koichi Kato, Yuji Teramura and Hiroo Iwata Advances in Tissue Engineering Approaches to Treatment of Intervertebral Disc Degeneration: Cells and Polymeric Scaffolds for Nucleus Pulposus Regeneration, by Jeremy J. Mercuri and Dan T. Simionescu Functionalized Biocompatible Nanoparticles for Site-Specific Imaging and Therapeutics, by Ranu K. Dutta, Prashant K. Sharma, Hisatoshi Kobayashi and Avinash C. Pandey
Nanoparticulate Drug Delivery Systems
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Author : Deepak Thassu
language : en
Publisher: CRC Press
Release Date : 2007-03-30
Nanoparticulate Drug Delivery Systems written by Deepak Thassu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-30 with Medical categories.
With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and e
Biodegradable Polyesters
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Author : Stoyko Fakirov
language : en
Publisher: John Wiley & Sons
Release Date : 2015-04-06
Biodegradable Polyesters written by Stoyko Fakirov and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-06 with Technology & Engineering categories.
Collating otherwise hard-to-get and recently acquired knowledge in one work, this is a comprehensive reference on the synthesis, properties, characterization, and applications of this eco-friendly class of plastics. A group of internationally renowned researchers offer their first-hand experience and knowledge, dealing exclusively with those biodegradable polyesters that have become increasingly important over the past two decades due to environmental concerns on the one hand and newly-devised applications in the biomedical field on the other. The result is an unparalleled overview for the industrial chemist and materials scientist, as well as for developers and researchers in industry and academia alike.
Silk Based Drug Delivery Systems
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Author : Elia Bari
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-10-07
Silk Based Drug Delivery Systems written by Elia Bari and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-07 with Science categories.
Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin.
Polyester Drug Delivery Systems
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Author : Trystan Worrell
language : en
Publisher: Foster Academics
Release Date : 2023-09-26
Polyester Drug Delivery Systems written by Trystan Worrell and has been published by Foster Academics this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-26 with Medical categories.
Polyester refers to a category of synthetic polymers built up from several chemical repeating units connected together by ester (CO-O) groups. They include both naturally occurring chemicals like those found in insects and plants, and synthetic chemicals like polybutyrate. Polyesters exhibit a diverse range of properties and useful applications. They are used as building blocks in drug delivery vehicles due to their properties of biodegradability and biocompatibility. Poly(caprolactones) (PCL), poly(dioxanone)s (PDO), poly(valerolactone)s (PVL), poly(lactide)s (PLA), poly(lactide-co-glycolide) (PLGA), poly(butyrolactone)s (PBL) and poly(glycolide)s (PGA) are some common polyesters utilized in drug delivery applications. The usage of polyester drug delivery systems may enhance bioavailability and pharmacokinetic properties, enable local administration, and prevent medication deactivation. This book elucidates prospective developments with respect to polyester drug delivery systems. Scientists and students actively engaged in the study of these drug delivery systems will find it full of crucial and unexplored concepts.
Degradable Aliphatic Polyesters
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Author : A.-C. Albertsson
language : en
Publisher: Springer
Release Date : 2003-07-03
Degradable Aliphatic Polyesters written by A.-C. Albertsson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07-03 with Technology & Engineering categories.
A renewed interest in aliphatic polyesters has resulted in developing materials important in the biomedical and ecological fields. Mainly materials such as PLA and PCL homopolymers have so far been used in most applications. There are many other monomers which can be used. Different molecular structures give a wider range of physical properties as well as the possibility of regulating the degradation rate. By using different types of initiators and catalysts, ring-opening polymerization of lactones and lactides provides macromolecules with advanced molecular architectures. In the future, new degradable polymers should be able to participate in the metabolism of nature. Some examples of novel polymers with inherent environmentally favorable properties such as renewability and degradability and a series of interesting monomers found in the metabolisms and cycles of nature are given.
Drug Delivery Systems
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Author : Stroeve Pieter
language : en
Publisher: World Scientific
Release Date : 2017-11-27
Drug Delivery Systems written by Stroeve Pieter and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-27 with Technology & Engineering categories.
With the alarming increase in cancer diagnoses and genetic illnesses, traditional drug agents and their delivery media need to be re-evaluated to address a quickly evolving field. With newer smart materials for the controlled release of macromolecules, peptides, genetic material, etc. further complications arise, such as material performance, synthesis, functionalization and targeting, biological identity, and biocompatibility. The book provides a comprehensive overview of the recent developments on "smart" targeting and drug delivery systems with a variety of carriers like nanoparticles, membranes, and hydrogels. It contains detailed descriptions on the recent trends in this field in the ongoing battle with catastrophic diseases like cancer. This field of research has been in its infancy and continues to face growth, and with it, further challenges and difficulties along the way toward maturity, which are accurately introduced in this book. Contents: Drug Delivery Systems: Possibilities and Challenges (Ryan Spitler, Saeid Zanganeh, Tahereh Jafari, Nasser Khakpash, Mohsen Erfanzadeh, Jim Q Ho, and Nastaran Sakhaie)Nanoparticles in Circulation: Blood Stability (Saeid Zanganeh, Tahereh Jafari, Nasser Khakpash, Mohsen Erfanzadeh, and Jim Q Ho)How do Nanoparticles (NPs) Pass Barriers? (Saeid Zanganeh, Ryan Spitler, Najme Javdani, and Jim Q Ho)Gated Porous Materials for Biomedical Application (Félix Sancenón, Erick Yu, Elena Aznar, M Dolores Marcos, and Ramón Martínez-Máñez)Controlled Release from Iron Oxide Nanoparticles (Masoud Rahman)The Reverse of Controlled Release: Controlled Sequestration of Species and Biotoxins into Nanoparticles (NPs) (Jenifer Gómez-Pastora, Eugenio Bringas, María Lázaro-Díez, José Ramos-Vivas, and Inmaculada Ortiz)Membranes for Controlled Release (Vida Araban, Neda Aslankoohi, and Mohammad Raoufi)Controlled Released from Hydrogel (Hossein Riahinezhad, Vida Araban, and Mohammad Raoufi)Nano Delivery Systems (Sophie Laurent, Afsaneh Lahooti, Saeed Shanehsazzadeh, and Robert N Muller)Legal Framework for Protection of Pharmaceutical Trade Marks in Europe and USA (Mohammad Hossein Erfanmanesh, and Shirin Sharifzadeh)Future Perspective on the Smart Delivery of Biomolecules (Erick Yu, Félix Sancenón, Elena Aznar, Ramón Martínez-Máñez, María Dolores Marcos, Mohammad J Hajipour, Morteza Mahmoudi, and Pieter Stroeve) Readership: Nanotechnologists; biomedical engineers; chemical engineers; materials scientists; biotechnology researchers; chemists; biological scientists; cell physiologists; medical scientists; gene therapists. Keywords: Drug Delivery Systems;Nanoparticles;Biomaterials;TargetingReview: Key Features: Comprehensive overview on "smart" targeting and drug delivery systemsUnderstanding of the biological identity of nanoparticles for drug delivery applicationsDetailed information on the legal framework for protection of pharmaceutical trade mark in Europe and the United States
Engineering Polymer Systems For Improved Drug Delivery
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Author : Rebecca A. Bader
language : en
Publisher: John Wiley & Sons
Release Date : 2014-01-17
Engineering Polymer Systems For Improved Drug Delivery written by Rebecca A. Bader and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-17 with Social Science categories.
Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.