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Alternative Methods Of Variable Selection In Linear Regression Models For Incomplete Multivariate Normal Data


Alternative Methods Of Variable Selection In Linear Regression Models For Incomplete Multivariate Normal Data
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Alternative Methods Of Variable Selection In Linear Regression Models For Incomplete Multivariate Normal Data


Alternative Methods Of Variable Selection In Linear Regression Models For Incomplete Multivariate Normal Data
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Author : Xiaowei Yang
language : en
Publisher:
Release Date : 2002

Alternative Methods Of Variable Selection In Linear Regression Models For Incomplete Multivariate Normal Data written by Xiaowei Yang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.




Topics On Bayesian Analysis Of Missing Data


Topics On Bayesian Analysis Of Missing Data
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Author : Yun Kai Jiang
language : en
Publisher:
Release Date : 2011

Topics On Bayesian Analysis Of Missing Data written by Yun Kai Jiang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.


This dissertation focuses on model selection in logistic regression with incompletely observed data. In particular, methods are presented for using Markov Chain Monte Carlo imputation and Bayesian variable selection to model a binary outcome. We consider multivariate missing covariates, with different types of predictors, such as continuous, counts, and categorical variables. Such type of data is considered in the analysis of Project Talent recorded from a longitudinal study. Roughly 400,000 were selected for the study from United States high school students in grades 9 through 12 during the year 1960; follow-up surveys were conducted 1, 5, and 11 years after graduation. We extend a methodology developed by Yang, Belin, and Boscardin (2005), to this Project Talent for a logistic regression model with incomplete covariates. The idea is to use data information as much as possible to fill in the missing values and study associations between a binary response variable and covariates. According to Yang, Belin, and Boscardin, one approach under a multivariate normal assumption for data, is to conduct Bayesian variable selection and missing data imputation simultaneously within one Gibbs Sampling process, called "Simultaneously Impute And Select" (SIAS). A modified strategy of SIAS is extended to a mixed data structure that allows for categorical, counts, and continuous variables. The first chapter consists of an introduction to some approaches to variable selection for missing data. The fact that missing data arise commonly in statistical analyses, leads to a variety of methods to handle missing data. The missing data mechanism needs to be considered in imputations. The multiple imputation methods and Markov Chain Mote Carlo (MCMC) algorithms are presented as general statistical approaches to missing data analysis. In the MCMC computational toolbox, various implementation methods for imputation are discussed: Metropolis-Hasting, Gibbs Sampler, and Data Augmentation. Compared to model selection methods in frequentist and likelihood inference, Bayesian inference takes an entirely different approach. The frequentist approach only looks at the current data to make inference. The Bayesian approach requires the specification of the prior distribution, which can come from historical data or expert opinion. Stochastic Search Variable Selection (SSVS) and Gibbs Variable Selection (GVS) are reviewed for model selection. Two alternative strategies, Impute Then Select (ITS) and Simultaneously Impute And Select (SIAS), are studied. In the second chapter, imputation and Bayesian variable selection methods for linear regression are extended to a binary response variable that is completely observed, but some covariates have missing values. We focus on extending SIAS strategy to logistic regression models via two alternative imputations, decomposition and Fully Conditional Specification (FCS). The decomposition method breaks a multivariate distribution into a series of univariate ones by decomposing the joint density function p(Y, X1, ..., X[p]) into the product of conditional distributions, using the factorization p(A, B) = p(A[vertical line]B)p(B). The FCS aims to involve iteratively sampling from the conditional distributions for one random variable, given all the others. These two methods are implemented in the imputation step of the SIAS procedure then applied to the Project Talent data. Simulations are also performed to validate these results and demonstrate the superiority of FCS over the decomposition method under certain circumstances. The third chapter presents a new approach for incorporating the sampling weight into imputation and Bayesian variable selection in logistic regression models. We develop the approach that extends SIAS by a Bayesian version of iterative weighted least squares algorithm to include a sampling step based on Gibbs sampler. This approach is illustrated using both simulation studies and Project Talent data.



Variable Selection By Regularization Methods For Generalized Mixed Models


Variable Selection By Regularization Methods For Generalized Mixed Models
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Author : Andreas Groll
language : en
Publisher: Cuvillier Verlag
Release Date : 2011-12-13

Variable Selection By Regularization Methods For Generalized Mixed Models written by Andreas Groll and has been published by Cuvillier Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-13 with Business & Economics categories.


A regression analysis describes the dependency of random variables in the form of a functional relationship. One distinguishes between the dependent response variable and one or more independent influence variables. There is a variety of model classes and inference methods available, ranging from the conventional linear regression model up to recent non- and semiparametric regression models. The so-called generalized regression models form a methodically consistent framework incorporating many regression approaches with response variables that are not necessarily normally distributed, including the conventional linear regression model based on the normal distribution assumption as a special case. When repeated measurements are modeled in addition to fixed effects also random effects or coefficients can be included. Such models are known as Random Effects Models or Mixed Models. As a consequence, regression procedures are applicable extremely versatile and consider very different problems. In this dissertation regularization techniques for generalized mixed models are developed that are able to perform variable selection. These techniques are especially appropriate when many potential influence variables are present and existing approaches tend to fail. First of all a componentwise boosting technique for generalized linear mixed models is presented which is based on the likelihood function and works by iteratively fitting the residuals using weak learners. The complexity of the resulting estimator is determined by information criteria. For the estimation of variance components two approaches are considered, an estimator resulting from maximizing the profile likelihood, and an estimator which can be calculated using an approximative EM-algorithm. Then the boosting concept is extended to mixed models with ordinal response variables. Two different types of ordered models are considered, the threshold model, also known as cumulative model, and the sequential model. Both are based on the assumption that the observed response variable results from a categorized version of a latent metric variable. In the further course of the thesis the boosting approach is extended to additive predictors. The unknown functions to be estimated are expanded in B-spline basis functions, whose smoothness is controlled by penalty terms. Finally, a suitable L1-regularization technique for generalized linear models is presented, which is based on a combination of Fisher scoring and gradient optimization. Extensive simulation studies and numerous applications illustrate the competitiveness of the methods constructed in this thesis compared to conventional approaches. For the calculation of standard errors bootstrap methods are used.



Flexible Imputation Of Missing Data Second Edition


Flexible Imputation Of Missing Data Second Edition
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Author : Stef van Buuren
language : en
Publisher: CRC Press
Release Date : 2018-07-17

Flexible Imputation Of Missing Data Second Edition written by Stef van Buuren and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-17 with Mathematics categories.


Missing data pose challenges to real-life data analysis. Simple ad-hoc fixes, like deletion or mean imputation, only work under highly restrictive conditions, which are often not met in practice. Multiple imputation replaces each missing value by multiple plausible values. The variability between these replacements reflects our ignorance of the true (but missing) value. Each of the completed data set is then analyzed by standard methods, and the results are pooled to obtain unbiased estimates with correct confidence intervals. Multiple imputation is a general approach that also inspires novel solutions to old problems by reformulating the task at hand as a missing-data problem. This is the second edition of a popular book on multiple imputation, focused on explaining the application of methods through detailed worked examples using the MICE package as developed by the author. This new edition incorporates the recent developments in this fast-moving field. This class-tested book avoids mathematical and technical details as much as possible: formulas are accompanied by verbal statements that explain the formula in accessible terms. The book sharpens the reader’s intuition on how to think about missing data, and provides all the tools needed to execute a well-grounded quantitative analysis in the presence of missing data.



Linear Models


Linear Models
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Author : Calyampudi Radhakrishna Rao
language : en
Publisher: Springer Science & Business Media
Release Date : 1999

Linear Models written by Calyampudi Radhakrishna Rao and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Mathematics categories.


This book provides an up-to-date account of the theory and applications of linear models. It can be used as a text for courses in statistics at the graduate level as well as an accompanying text for other courses in which linear models play a part. The authors present a unified theory of inference from linear models with minimal assumptions, not only through least squares theory, but also using alternative methods of estimation and testing based on convex loss functions and general estimating equations. The bookincludes a discussion of: -- sensitivity analysis and model selection -- incomplete data sets including regression diagnostics to identify Non-MCAR-processes -- the analysis of categorical data based on a unified presentation of generalized linear models including GEE-methods for correlated response. An extensive appendix on matrix theory will be useful to researchers in econometrics, engineering, and optimization theory.



Alternative Methods For Variable Selection In Generalized Linear Models With Binary Outcomes And Incomplete Covariates


Alternative Methods For Variable Selection In Generalized Linear Models With Binary Outcomes And Incomplete Covariates
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Author : Gang Liu
language : en
Publisher:
Release Date : 2007

Alternative Methods For Variable Selection In Generalized Linear Models With Binary Outcomes And Incomplete Covariates written by Gang Liu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.




Shrinkage Based Variable Selection Methods For Linear Regression And Mixed Effects Models


Shrinkage Based Variable Selection Methods For Linear Regression And Mixed Effects Models
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Author :
language : en
Publisher:
Release Date : 2004

Shrinkage Based Variable Selection Methods For Linear Regression And Mixed Effects Models written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.


KRISHNA, ARUN. Shrinkage-Based Variable Selection Methods for Linear Regression and Mixed-Effects Models. (Under the direction of Professors H.D. Bondell and S.K. Ghosh). In this dissertation we propose two new shrinkage-based variable selection approaches. We first propose a Bayesian selection technique for linear regression models, which allows for highly correlated predictors to enter or exit the model, simultaneously. The second variable selection method proposed is for linear mixed-effects models, where we develop a new technique to jointly select the important fixed and random effects parameters. We briefly summarize each of these methods below. The problem of selecting the correct subset of predictors within a linear model has received much attention in recent literature. Within the Bayesian framework, a popular choice of prior has been Zellnerâ€"! g-prior which is based on the inverse of empirical covariance matrix of the predictors. We propose an extension of Zellnerâ€"! gprior which allow for a power parameter on the empirical covariance of the predictors. The power parameter helps control the degree to which correlated predictors are smoothed towards or away from one another. In addition, the empirical covariance of the predictors is used to obtain suitable priors over model space. In this manner, the power parameter also helps to determine whether models containing highly collinear predictors are preferred or avoided. The proposed power parameter can be chosen via an empirical Bayes method which leads to a data adaptive choice of prior. Simulation studies and a real data example are presented to show how the power parameter is well determined from the degree of cross-correlation within predictors. The proposed modification compares favorably to the standard use of Zellnerâ€"! prior and an intrinsic prior in these examples. We propose a new method of simultaneously identifying the important predictors that correspond to both the fixed and random effects.



Multiple Imputation Of Missing Data In Practice


Multiple Imputation Of Missing Data In Practice
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Author : Yulei He
language : en
Publisher: CRC Press
Release Date : 2021-11-20

Multiple Imputation Of Missing Data In Practice written by Yulei He and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-20 with Mathematics categories.


Multiple Imputation of Missing Data in Practice: Basic Theory and Analysis Strategies provides a comprehensive introduction to the multiple imputation approach to missing data problems that are often encountered in data analysis. Over the past 40 years or so, multiple imputation has gone through rapid development in both theories and applications. It is nowadays the most versatile, popular, and effective missing-data strategy that is used by researchers and practitioners across different fields. There is a strong need to better understand and learn about multiple imputation in the research and practical community. Accessible to a broad audience, this book explains statistical concepts of missing data problems and the associated terminology. It focuses on how to address missing data problems using multiple imputation. It describes the basic theory behind multiple imputation and many commonly-used models and methods. These ideas are illustrated by examples from a wide variety of missing data problems. Real data from studies with different designs and features (e.g., cross-sectional data, longitudinal data, complex surveys, survival data, studies subject to measurement error, etc.) are used to demonstrate the methods. In order for readers not only to know how to use the methods, but understand why multiple imputation works and how to choose appropriate methods, simulation studies are used to assess the performance of the multiple imputation methods. Example datasets and sample programming code are either included in the book or available at a github site (https://github.com/he-zhang-hsu/multiple_imputation_book). Key Features Provides an overview of statistical concepts that are useful for better understanding missing data problems and multiple imputation analysis Provides a detailed discussion on multiple imputation models and methods targeted to different types of missing data problems (e.g., univariate and multivariate missing data problems, missing data in survival analysis, longitudinal data, complex surveys, etc.) Explores measurement error problems with multiple imputation Discusses analysis strategies for multiple imputation diagnostics Discusses data production issues when the goal of multiple imputation is to release datasets for public use, as done by organizations that process and manage large-scale surveys with nonresponse problems For some examples, illustrative datasets and sample programming code from popular statistical packages (e.g., SAS, R, WinBUGS) are included in the book. For others, they are available at a github site (https://github.com/he-zhang-hsu/multiple_imputation_book)



Variable Selection With Incomplete Covariate Data


Variable Selection With Incomplete Covariate Data
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Author :
language : en
Publisher:
Release Date : 2007

Variable Selection With Incomplete Covariate Data written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.




Secondary Analysis Of Electronic Health Records


Secondary Analysis Of Electronic Health Records
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Author : MIT Critical Data
language : en
Publisher: Springer
Release Date : 2016-09-09

Secondary Analysis Of Electronic Health Records written by MIT Critical Data and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-09 with Medical categories.


This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a “data desert” when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients.