Alzheimer 100 Years And Beyond
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Alzheimer 100 Years And Beyond
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Author : Mathias Jucker
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-11-22
Alzheimer 100 Years And Beyond written by Mathias Jucker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-11-22 with Medical categories.
Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4, 1906 in Tübingen. The celebratory event "Alzheimer 100 Years and Beyond" was organized through the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen. This volume, a collection of articles by the invited speakers and of a few other prominent researchers, is published as a record of those events.
Alzheimer S Disease
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Author :
language : en
Publisher:
Release Date : 2006
Alzheimer S Disease written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.
Beyond Alzheimer S
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Author : Scott D. Mendelson
language : en
Publisher: Government Institutes
Release Date : 2009-09-16
Beyond Alzheimer S written by Scott D. Mendelson and has been published by Government Institutes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-16 with Health & Fitness categories.
Explains that rather than being the inevitable result of age and genetics, dementia is primarily due to poor lifestyle choices, and offers prescriptive advice to mitigate or delay its onset.
A Long Goodbye And Beyond
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Author : Linda Combs
language : en
Publisher:
Release Date : 1999
A Long Goodbye And Beyond written by Linda Combs and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.
Alzheimer's, the frightening disease of aging, is treated heroically in a touching book by a woman who left her important position as Assistant Secretary for Management at the U.S. Department of Treasury to care for her mother. After her mother's medical verdict of increasing memory loss was pronounced, Linda Combs resigned her executive post in Washington, D.C., and moved home to North Carolina.Her familiarity with Alzheimer's prompted Linda Combs to write her book, A Long Goodbye and Beyond, as a resource for other parental caregivers, like herself, who must assist a loved one to pass through the stages of unlovely deterioration.To this book of instruction, courage, kindness, sympathy and loyalty to the idea of a new life beyond, artist Tom Novak lends his marvelous illustrations, which are a tribute to brave souls who have the long loneliness of slow disintegration.
Dementias
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Author : Charles Duyckaerts
language : en
Publisher: Elsevier
Release Date : 2008-06-09
Dementias written by Charles Duyckaerts and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-09 with Medical categories.
This volume provides a comprehensive understanding of the biology of dementias, including information on advancements in the way these disorders are perceived and studied. From earlier assumptions that cognitive deficits were simply age related, this handbook progresses into complex discussions of the diseases that affect the cortex of the human brain. Clinicians will find extensive diagnostic and research perspectives on a variety of interesting topics, including neuropathology, physiopathology, biology, clinics, and imaging information on all, or most, of the dementing disorders currently known. In addition, chapters devoted to legal and ethical issues give practitioners and health care workers an informative view on complex dementias and the way these disorders affect patients and families. Clinicians in all levels of expertise will find useful and synthetic information. * Comprehensive information on advancements in the study and diagnosis of dementias * Complex discussions of the diseases that affect the cortex of the human brain * Extensive diagnostic and research perspectives on topics including, but not limited to, neuropathology, physiopathology, and groundbreaking imaging techniques * A reference guide that is appropriate for clinicians in all levels of expertise, from researchers to basic health care providers
Alzheimer S Disease Research
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Author : Christian Behl
language : en
Publisher: Springer Nature
Release Date : 2023-08-14
Alzheimer S Disease Research written by Christian Behl and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-14 with Medical categories.
This book highlights the key phases and central findings of Alzheimer’s Disease research since the introduction of the label ‘Alzheimer’s Disease’ in 1910. The author, Christian Behl, puts dementia research in the context of the respective zeitgeist and summarizes the paths that have led to the currently available Alzheimer’s drugs. As the reader is taken through the major developments in Alzheimer's Disease research, particularly over the past thirty years, Behl poses critical questions: Why are the exact causes of Alzheimer's Disease still in the dark, despite all the immense, worldwide research efforts in academia as well as in the pharmaceutical industry? Why has the majority of an entire research field kept focusing on a single hypothesis that establishes the deposition of the amyloid beta peptide in the brain as the key trigger of Alzheimer's pathology, even though this concept has still not been convincingly proven in the clinics? Are there other hypotheses that might explain the pathogenesis of this complex brain disease, and if so, why were these perspectives not adequately followed? In this book, Behl tries to answer these questions. Starting with the historical background, the author illustrates the long and arduous research journey, its numerous setbacks, and the many alternative explanations for the disease, which have started gaining increasing attention and acceptance in the Alzheimer’s research community only more recently. With his deep dive into the history and progression of this research, including the most recent developments, Behl explains why he believes that it is high time to promote a paradigm shift in Alzheimer’s Disease research. The book is written for all researchers in the fields of neurobiology and neurodegeneration, as well as other biomedical fields, who would like to gain a broad and beyond the surface insight into (the key developments of) one of the most promoted research fields of our time. With its extensive literature references and over 100 illustrations, the book is also attractive for students and interested lay persons. Elaborating on all the different aspects and research approaches of this research field, the author aims to convince the reader that the underlying causes of Alzheimer’s Disease may be much more complex than previously thought and that this must be considered for future research directions. While he hopes that the Alzheimer’s research community is finally ready to shed its ‘amyloid-straitjacket’ that has hampered progress for too long, he is also convinced that a much-needed paradigm shift can guide future Alzheimer’s Disease research and provide a new and broader perspective on this age-dependent brain disease.
Mind Thief
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Author : Han Yu
language : en
Publisher: Columbia University Press
Release Date : 2021-03-02
Mind Thief written by Han Yu and has been published by Columbia University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-02 with Science categories.
Alzheimer’s disease, a haunting and harrowing ailment, is one of the world’s most common causes of death. Alzheimer’s lingers for years, with patients’ outward appearance unaffected while their cognitive functions fade away. Patients lose the ability to work and live independently, to remember and recognize. There is still no proven way to treat Alzheimer’s because its causes remain unknown. Mind Thief is a comprehensive and engaging history of Alzheimer’s that demystifies efforts to understand the disease. Beginning with the discovery of “presenile dementia” in the early twentieth century, Han Yu examines over a century of research and controversy. She presents the leading hypotheses for what causes Alzheimer’s; discusses each hypothesis’s tangled origins, merits, and gaps; and details their successes and failures. Yu synthesizes a vast amount of medical literature, historical studies, and media interviews, telling the gripping stories of researchers’ struggles while situating science in its historical, social, and cultural contexts. Her chronicling of the trajectory of Alzheimer’s research deftly balances rich scientific detail with attention to the wider implications. In narrating the attempts to find a treatment, Yu also offers a critical account of research and drug development and a consideration of the philosophy of aging. Wide-ranging and accessible, Mind Thief is an important book for all readers interested in the challenge of Alzheimer’s.
Molecular Pathology Of Alzheimer S Disease
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Author : Rudy Castellani
language : en
Publisher: Biota Publishing
Release Date : 2013-10-01
Molecular Pathology Of Alzheimer S Disease written by Rudy Castellani and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-01 with Health & Fitness categories.
Alzheimer’s Disease is characterized pathologically by two principal hallmark lesions: the senile plaque and the neurofibrillary tangle. Since the identification of each over 100 years ago, the major protein components have been elucidated. This has led in turn to the elaboration of metabolic cascades involving amyloid-β production in the case of the senile plaque, and phosphorylated-tau protein in the case of the neurofibrillary tangle. The pathogenesis and histogenesis of each have been the source of extensive investigation and some controversy in recent years, as both cascades have been implicated in the pathogenesis of Alzheimer’s Disease, relied upon in the diagnostic criteria for Alzheimer’s Disease at autopsy, and targeted for therapeutic intervention. With the accumulation of data and expansion of knowledge of the molecular biology of Alzheimer’s Disease, it appears that the enthusiasm for successful intervention has been premature. In this book, we detail the discovery and characterization of the major pathological lesions, their associated molecular biology, their relationship to clinical disease, and potential fundamental errors in understanding that may be leading scientific investigators in unintended directions.
Beyond Forgetting
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Author : Holly J. Hughes
language : en
Publisher: Literature & Medicine
Release Date : 2009
Beyond Forgetting written by Holly J. Hughes and has been published by Literature & Medicine this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Medical categories.
This is a literary collection that illuminates the darkness of Alzheimer's disease. It is a unique collection of poetry and short prose about the disease written by 100 contemporary writers - doctors, nurses, social workers, hospice workers, daughters, sons, wives, and husbands - whose lives have been touched by the disease.
Neuroanatomy And Pathology Of Sporadic Alzheimer S Disease
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Author : Heiko Braak
language : en
Publisher: Springer
Release Date : 2014-12-11
Neuroanatomy And Pathology Of Sporadic Alzheimer S Disease written by Heiko Braak and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-11 with Medical categories.
As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail