Analysis Of Cardiac Development
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Analysis Of Cardiac Development
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Author : Rafael Beyar
language : en
Publisher: John Wiley & Sons
Release Date : 2010-03-22
Analysis Of Cardiac Development written by Rafael Beyar and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-22 with Science categories.
This volume, the result of three days of interactive sessions among world leaders in the cardiac sciences, summarizes the most up-to-date information about development and cardiogenesis signaling in cell-based therapy, as well as developmental aspects of the formation of the embryonic heart, including the effect of mechanical load on differentiation. Other topics covered include: signaling and repair strategies, cell and gene therapy for the treatment of postmyocardial infarction, signaling, vascularization methods in engineering embryonic cardiac tissue, and molecular methods to improve survival of human embryonic stem cell–derived cardiomyocytes; developmental and evolutional cardiology; novel strategies for treatment of atrial fibrillation and channel molecular physiology in remodeling and hypertrophy; multiscale modeling for metabolism and flows, including force development, mechanics of cardiac contraction, and ATP supply and demand aspects; aging, interactions, and interference aspects include fibroblast-myocyte-capillary communications, nonuniformities in contraction, calcium channels as oxygen sensors, and epigenetics of heart failure; and macroscale phenomena and clinical aspects, including various clinical aspects of modern cardiology such as navigation methods for cardiac interventions and control of cardiac function by changes in energetic demand. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
Development Of The Cardiac Conduction System
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Author : Derek J. Chadwick
language : en
Publisher: John Wiley & Sons
Release Date : 2005-01-21
Development Of The Cardiac Conduction System written by Derek J. Chadwick and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-21 with Medical categories.
The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat. Dysfunction of this system can be a direct cause of cardiac conduction disturbance, arrhythmias and sudden cardiac death. A wealth of information has been collected over many years on the unique histological, morphological and phenotypic characteristics of specialized cardiac tissues. The cellular and molecular mechanisms that govern development of the PCS are now starting to be understood. This book draws together contributions from an international and interdisciplinary group of experts working on both basic and clinical aspects of cardiac development. It features reviews of the structure and function of the developing PCS, discussion of the molecular and cellular mechanisms regulating embryological development of this system and studies on the fundamental basis of PCS pathology. The book also considers how novel therapeutic interventions based on understanding of the developmental biology of cardiac pacemaking and conduction tissues might ultimately impact on clinical medicine.
Heart Development And Regeneration
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Author : Nadia Rosenthal
language : en
Publisher: Academic Press
Release Date : 2010-05-28
Heart Development And Regeneration written by Nadia Rosenthal and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-28 with Science categories.
The development of the cardiovascular system is a rapidly advancing area in biomedical research, now coupled with the burgeoning field of cardiac regenerative medicine. A lucid understanding of these fields is paramount to reducing human cardiovascular diseases of both fetal and adult origin. Significant progress can now be made through a comprehensive investigation of embryonic development and its genetic control circuitry. Heart Development and Regeneration, written by experts in the field, provides essential information on topics ranging from the evolution and lineage origins of the developing cardiovascular system to cardiac regenerative medicine. A reference for clinicians, medical researchers, students, and teachers, this publication offers broad coverage of the most recent advances. Volume One discusses heart evolution, contributing cell lineages; model systems; cardiac growth; morphology and asymmetry; heart patterning; epicardial, vascular, and lymphatic development; and congenital heart diseases. Volume Two includes chapters on transcription factors and transcriptional control circuits in cardiac development and disease; epigenetic modifiers including microRNAs, genome-wide mutagenesis, imaging, and proteomics approaches; and the theory and practice of stem cells and cardiac regeneration. - Authored by world experts in heart development and disease - New research on epigenetic modifiers in cardiac development - Comprehensive coverage of stem cells and prospects for cardiac regeneration - Up-to-date research on transcriptional and proteomic circuits in cardiac disease - Full-color, detailed illustrations
Cardiac Development
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Author : Margaret L. Kirby
language : en
Publisher: Oxford University Press
Release Date : 2007-03-22
Cardiac Development written by Margaret L. Kirby and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-22 with Medical categories.
This is the only in-depth, single author survey of heart development. It will provide a more systematic, up-to-date synthesis of the subject than any other volume, spanning the range from classical anatomical studies to recent findings in molecular biology. It also covers topics that are often omitted from discussions of heart development, such as myocardial function, cardiac innervation, and conduction development and clinical correlates will be discussed throughout. The book is beautifully illustrated by Karen Waldo, an artist who has collaborated with Dr. Kirby for many years.
Molecular Biology Of Cardiac Development And Growth
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Author : Paul J.R. Barton
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-21
Molecular Biology Of Cardiac Development And Growth written by Paul J.R. Barton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-21 with Science categories.
This book is concerned with basic molecular biology and how research in this field relates to our understanding of molecular and cellular aspects of cardiac development and growth. The authors point out that molecular biology has provided a wealth of new approaches for investigating cellular processes at the molecular level and is now making a significant contribution to the understanding of the molecular mechanisms underlying cardiac development and providing insight into the molecular events underlying cardiac malformation and disease. This volume combines basic information on molecular biology with current thinking in cardiac development. It is the only book to specifically do this.
The Esc Textbook Of Cardiovascular Development
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Author : José M. Pérez-Pomares
language : en
Publisher: Oxford University Press
Release Date : 2018-07-12
The Esc Textbook Of Cardiovascular Development written by José M. Pérez-Pomares and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-12 with Medical categories.
This highly illustrated textbook has been prepared by the Working Group on Development, Anatomy and Pathology of the European Society of Cardiology (ESC). The ESC Textbook of Cardiovascular Development is the authority on cardiovascular development from a perspective of both basic scientists and clinicians. The embryonic origin of congenital heart diseases and their pathology has been analysed in depth. Modern concepts pivotal to the understanding of cardiovascular morphogenesis, including those still subject to controversy, have been highlighted and the content covers the ESC Core Curriculum. The textbook will appeal to researchers and clinicians from a wide spectrum of disciplines including molecular and developmental biologists working on mechanisms of heart development in a range of model organisms as well as pathologists, morphologists, geneticists, and cardiologists.
Cardiovascular Development
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Author : Rolf Bodmer
language : en
Publisher: Elsevier
Release Date : 2007-11-13
Cardiovascular Development written by Rolf Bodmer and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-13 with Medical categories.
In 1993, Rolf Bodmer described a gene he named tinman that was required for the formation of the dorsal aorta of the fly. Flies without a functional tinman gene had no heart. Quickly, mammalian counterparts of the tinman gene were identified and found to be expressed by early cardiomyogenic precursors and by cardiomyocytes throughout heart development. Since then, significant progress has been made in the understanding of molecular and genetic determinants of heart formation. An ever growing number of genes have been identified that are required for cardiogenesis, as evidenced by severe abnormalities in cardiac development produced by inactivation in the mouse or inhibition of gene function in other model organisms. Cardiovascular Development covers some of the latest research in the study of heart formation. Volume Editor Rolf Bodmer has assembled a world-class list of contributors whose research uses a variety of animal models and whose findings are certain to enhance our understanding of this exciting field. * Ties together the development of heart morphology and conduction system * The latest developments in vertebrate and invertebrate genetic model systems * Technological advancements in cardiovascular science
Sex Specific Analysis Of Cardiovascular Function
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Author : Peter L. M. Kerkhof
language : en
Publisher: Springer
Release Date : 2018-07-26
Sex Specific Analysis Of Cardiovascular Function written by Peter L. M. Kerkhof and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-26 with Medical categories.
This book gathers together contributions from internationally renowned authors in the field of cardiovascular systems and provides crucial insight into the importance of sex- and gender-concepts during the analysis of patient data. This innovative title is the first to offer the elements necessary to consider sex-related properties in both clinical and basic studies regarding the heart and circulation on multiscale levels (i.e. molecular, cellular, electrophysiologically, neuroendocrine, immunoregulatory, organ, allometric, and modeling). Observed differences at (ultra)cellular and organ level are quantified, with focus on clinical relevance and implications for diagnosis and patient management. Since the cardiovascular system is of vital importance for all tissues, Sex-Specific Analysis of Cardiovascular Function is an essential source of information for clinicians, biologists, and biomedical investigators. The wide spectrum of differences described in this book will also act as an eye-opener and serve as a handbook for students, teachers, scientists and practitioners.
Single Cell Omics Analyses In Cardiovascular Diseases
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Author :
language : en
Publisher: Frontiers Media SA
Release Date : 2024-05-14
Single Cell Omics Analyses In Cardiovascular Diseases written by and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-14 with Medical categories.
Single-cell OMICs analyses have recently become one of the most promising tools to probe biology at the cellular level, in large part due to its ability to address issues beyond the bulk analysis – a window into cellular heterogeneity. The ability to profile transcriptomic, epigenomic, proteomics, and metabolomics at the single cell level including more recently the spatial information has enhanced our ability to understand interactions between biomolecules in different contexts leading to the discovery of specific cellular subpopulations as well as biological mechanisms underlying pathologies which may be amenable to therapeutic interventions. The scale and availability of a variety of technologies to measure intricate molecular details have provided an impetus to research in many disease areas, including cardiovascular medicine.
Molecular Mechanism Of Congenital Heart Disease And Pulmonary Hypertension
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Author : Toshio Nakanishi
language : en
Publisher: Springer Nature
Release Date : 2020-02-28
Molecular Mechanism Of Congenital Heart Disease And Pulmonary Hypertension written by Toshio Nakanishi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-28 with Medical categories.
This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.