Analytical And Chromatographic Techniques In Radiopharmaceutical Chemistry
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Analytical And Chromatographic Techniques In Radiopharmaceutical Chemistry
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Author : Donald M. Wieland
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Analytical And Chromatographic Techniques In Radiopharmaceutical Chemistry written by Donald M. Wieland and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In 1906, Michael T. Sweet first developed the chromatographic method by using an adsorbant to separate pigments. Since that time, the technological advances in TLC and HPLC have brought about new definitions of purity in parallel with the advances. Radiopharmaceutical chemistry is especially dependent on the chromat ographic technique because of the relatively small amount of material in most radiopharmaceuticals-often so small that the usual physical methods of analytical chemistry cannot be used. As a result, this collection of papers represents the key to successful radiopharmaceutical development by setting the standard for the pres of radiochemical purity. ent-day definition William C. Eckelman, Ph.D. Diagnostics Associate Director The Squibb Institute for Medical Research New Brunswick, New Jersey Preface The chapters herein are updated and expanded versions of presentations that the authors made at a symposium held on June 4, 1984 in Los Angeles, California under the sponsorship of the Radiopharmaceutical Science Council of the Society of Nuclear Medicine. All manuscripts were refereed. The intent of the symposium organizers was to enlist participants who work on a day-to-day basis with the analytical and chromatographic techniques to be discussed at the symposium. We feel confident that this distillation of hands-on experience will be of value to graduate students as well as experienced researchers in radio pharmaceutical chemistry and related fields which use radiotracer methodology.
Thin Layer Chromatography In Drug Analysis
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Author : Lukasz Komsta
language : en
Publisher: CRC Press
Release Date : 2013-12-20
Thin Layer Chromatography In Drug Analysis written by Lukasz Komsta and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-20 with Medical categories.
Used routinely in drug control laboratories, forensic laboratories, and as a research tool, thin layer chromatography (TLC) plays an important role in pharmaceutical drug analyses. It requires less complicated or expensive equipment than other techniques, and has the ability to be performed under field conditions. Filling the need for an up-to-date
Quantitative Chromatographic Analysis
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Author : Thomas Beesley
language : en
Publisher: CRC Press
Release Date : 2000-12-06
Quantitative Chromatographic Analysis written by Thomas Beesley and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-12-06 with Science categories.
Highlights critical factors involved in successful chromatographic analysis. Details analytical procedures; outlining sample preparation, collection, transportation, and storage. Provides step-by-step guidelines for producing analytical reports.
Gas And Liquid Chromatography In Analytical Chemistry
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Author : Roger Malcolm Smith
language : en
Publisher:
Release Date : 1988
Gas And Liquid Chromatography In Analytical Chemistry written by Roger Malcolm Smith and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Gas chromatography categories.
Technetium 99m Pharmaceuticals
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Author : Ilse Zolle
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-01-28
Technetium 99m Pharmaceuticals written by Ilse Zolle and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-28 with Medical categories.
Radioactive drug development is a multi-disciplinary task. Therefore, dedicated scientists and experts from different fields of specialisation have contributed to this book. The text reviews forty years of advances in radiopharmaceutical development based on Technetium. The first section reviews basic principles and analytic methods, and information on chemical makeup of radiopharmaceuticals. Part 2 reviews 99mTc-radiopharmaceuticals used in nuclear medicine, thoroughly outlining their chemistry, formulation, pharmacokinetics and clinical applications.
New Trends In Radiopharmaceutical Synthesis Quality Assurance And Regulatory Control
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Author : Ali M. Emran
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-09
New Trends In Radiopharmaceutical Synthesis Quality Assurance And Regulatory Control written by Ali M. Emran and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-09 with Medical categories.
Marking the 200th National Meeting of the American Chemical Society, The Division of Nuclear Chemistry and Technology hosted a group of about 90 scientists from 15 different countries to discuss the new trends in radiopharmaceutical synthesis, quality assurance and regulatory control. This event took place in Washington, D.C. on August 27-30, 1990. When I first suggested the idea for this symposium, a group of scientists who pioneered the proposed topics offered their help to organize and run such a big task with me. Their names are listed here in appreciation. Thomas E. Boothe Cyclotron Facility, Mt. Sinai Medical Center, Miami Beach, Florida, USA Robert F. Dannals Division of Nuclear Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA Anthony L. Feliu Julich Nuclear Research Center, Julich, Germany Joanna S. Fowler Chemistry Department, Brookhaven National Laboratory, Upton, New York, USA George W. Kabalka Department of Chemistry, University of Tennessee, Knoxville, Tennessee, USA Hank F. Kung Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA James F. Lamb Imagents, Inc., Houston, Texas, USA Harold A. O'Brien, Jr. Los Alamos National Laboratory, Los Alamos, New Mexico, USA Joseph R. Peterson Dept. of Chemistry, University of Tennessee, Knoxville, Tennessee, USA Hernan Vera Ruiz International Atomic Energy Agency, Vienna, Austria Roy S. Tilbury University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA In addition, a number of distinguished colleagues have participated in the process of reviewing the manuscripts presented in this volume. Their effort is sincerely acknowledged.
Practical Application Of Supercritical Fluid Chromatography For Pharmaceutical Research And Development
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Author :
language : en
Publisher: Elsevier
Release Date : 2022-12-02
Practical Application Of Supercritical Fluid Chromatography For Pharmaceutical Research And Development written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-02 with Science categories.
Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development provides a valuable “go-to reference for many difficult-to-solve challenges using pertinent chromatographic theory, first-hand case studies, and examples provided from academic and industry experts. This text also enables professors teaching an analytical instrumental course to introduce and instruct students about one of the most sustainable and powerful separation methods currently available. While the text has broad applicability across industrial sectors, it focuses primarily on application in the pharmaceutical industry. The book is designed to allow readers to align current HPLC/UHPLC capabilities with SFC as an orthogonal tool for project specific methods in the pharmaceutical industry. It highlights where SFC falls on the spectrum of useful chromatographic tools for routine and challenging separative methods. Experienced HPLC users who are interested in developing knowledge in orthogonal separation techniques, as well as newcomers to the field of separation science, will find this text particularly useful. Chapters address where SFC may fit the analytical needs of the pharmaceutical industry and alert the readers as to where the technique will not fit. Readers will gain an understanding of how and where SFC may be applied and adapted more routinely across the pharmaceutical industry as a ‘green’ way of undertaking separation opportunities and challenges. Areas within the pharmaceutical industry include early drug discovery, process chemistry, and late stage development and manufacturing. Describes approaches to SFC column and mobile phase selection for method development for both analytical and preparative tasks Gives practical examples of how analytical SFC enables the monitoring of synthetic reactions including unstable intermediates, chiral and achiral polar reactants and products across small and large modalities Provides need-focused case studies for pharmaceutical analysts, process chemists, and contract chemistry facilities that can benefit from monitoring or purifying polar intermediates, mutagenic impurities, nitrosamines and other reaction by-products including excipients and metabolites
Clinical Analysis By Thin Layer Chromatography Techniques
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Author : Ronald McLean Scott
language : en
Publisher:
Release Date : 1969
Clinical Analysis By Thin Layer Chromatography Techniques written by Ronald McLean Scott and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1969 with Chromatographic analysis categories.
Multidimensional Chromatography
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Author : Hernan J. Cortes
language : en
Publisher: CRC Press
Release Date : 2020-07-24
Multidimensional Chromatography written by Hernan J. Cortes and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-24 with Science categories.
This book summarizes all the important aspects of multidimensional separations, providing information on gas, liquid and thin-layer chromatography, as well as the techniques and applications of supercritical fluid chromatography in the multidimensional mode.
Analytical Control Of Radiopharmaceuticals
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Author : International Atomic Energy Agency
language : en
Publisher:
Release Date : 1970
Analytical Control Of Radiopharmaceuticals written by International Atomic Energy Agency and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with Medical categories.