Animal Models Of Neuropsychiatric Diseases
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Animal Models Of Neuropsychiatric Diseases
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Author : Michael Koch
language : en
Publisher: World Scientific
Release Date : 2006-05-11
Animal Models Of Neuropsychiatric Diseases written by Michael Koch and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-05-11 with Medical categories.
Animal models of neuro- and psychopathological states in humans are an indispensable part of both experimental neurology and biological psychiatry. Written by a team of experts, this book provides an up-to-date detailed overview of the current approaches to the design of viable animal models for eight prominent neuropsychiatric diseases. The book is specifically written with the research-oriented reader in mind — both in academia and the pharmaceutical industry. It contains first-hand information on how to design viable animal models for Alzheimer's disease, epilepsy, Huntington's disease, Parkinson's disease, addiction, depression, fear and anxiety, and schizophrenia. Each chapter also critically discusses the limitations of the animal experimental approach towards an understanding of human neuropsychiatric disorders.The book is an essential source of reference for researchers who seek to successfully continue and elaborate the experimental work that will finally lead to a better understanding of the neurobiological basis of the diseases, as well as to an improvement of both diagnosis and therapy.
Animal Models In Psychiatry I
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Author : Alan A. Boulton
language : en
Publisher: Springer Science & Business Media
Release Date : 1991-08-20
Animal Models In Psychiatry I written by Alan A. Boulton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-08-20 with Medical categories.
The two Animal Models in Psychiatry volumes are loosely organized by subject. The first volume contains a number of chapters concerned with schizophrenia, psyc- ses, neuroleptic-induced tardive dyskinesias, and other d- orders that may involve dopamine, such as attention deficit disorder and mania. The second volume deals with affective and anxiety disorders, but also includes chapters on subjects not easily classified as either psychotic, or affective, or an- ety-related, such as aggression, mental retardation, and memory disorders. Four chapters on animal models of schizophrenia or psychoses are included in the present v- ume because of the importance of these disorders in p- chiatry. Likewise, three chapters in the subsequent volume deal with depression. The first of the two volumes begins with an introd- tion by Paul Willner reviewing the criteria for assessing the validity of animal models in psychiatry. He has written - tensively on this subject, and his thorough description of the issues of various forms of validity provides a framework in which to evaluate the subsequent chapters. As will be seen, the remaining chapters in both volumes will refer frequently to these issues. The second chapter, by Melvin Lyon, describes a large number of different procedures that have been p- posed as potential animal models of schizophrenia. This is a departure from the usual format, consisting of detailed - scriptions of specific models.
Modeling Neuropsychiatric Disorders In Laboratory Animals
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Author : Kurt Leroy Hoffman
language : en
Publisher: Woodhead Publishing
Release Date : 2015-08-28
Modeling Neuropsychiatric Disorders In Laboratory Animals written by Kurt Leroy Hoffman and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-28 with Medical categories.
Modeling Neuropsychiatric Disorders in Laboratory Animals serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals interested in the use of animal models in preclinical research related to human neuropsychiatric disorders. The text focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders. Chapters contain discussions on both classical and modern views on the validation of animal models for neuropsychiatric disorders, also discussing the utility of endophenotypes in modeling neuropsychiatric disease. Subsequent chapters deal with four specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders. Final sections discuss the future for the development, validation, and use of animal models in basic and preclinical research. Focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders Serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals Discusses specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders
Transgenic And Knockout Models Of Neuropsychiatric Disorders
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Author : Gene S. Fisch
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-06
Transgenic And Knockout Models Of Neuropsychiatric Disorders written by Gene S. Fisch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-06 with Medical categories.
In this up-to-date survey and critical assessment of transgenic and knockout models in neuropsychiatry and behavior, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond. The authors focus on transgenic and knockout models of neurocognitive dysfunction and neuropsychiatric dysfunction. The discussion of neurobiological problems covers mental retardation, polyglutamate, and speech disorders, as well as disorders that involve cognitive, social, speech, and language dysfunction. The neuropsychiatric dysfunctions examined include psychosis and schizophrenia, anxiety, depression, and bipolar disorder.
Molecular And Functional Models In Neuropsychiatry
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Author : Jim J. Hagan
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-04-02
Molecular And Functional Models In Neuropsychiatry written by Jim J. Hagan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-02 with Medical categories.
The development of more effective treatments for neuropsychiatric disorders requires scientific progress on a broad front. Animal models have a vital role to play in advancing the field. When deployed in conjunction with detailed study of these diseases in man they bring the power to make controlled experimental interventions which allow the functional consequences of genetic variations and polymorphisms to be understood in terms of their cellular, systems and behavioural effects. Further, they provide a means by which complex cognitive and behavioural phenomena may be dissected and understood. Finally, they provide a bridge to understanding the effects of drugs on the functioning of the central nervous system, thereby improving our understanding of the actions of those drugs in man.
Animal Models Of Neurological Disease Ii
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Author : Alan A. Boulton
language : en
Publisher: Humana
Release Date : 2013-08-11
Animal Models Of Neurological Disease Ii written by Alan A. Boulton and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-11 with Medical categories.
to the Animal Models Volumes This and several other volumes in the Neuromethods series will describe a number of animal models of neuropsychiatric disorders. Because of increasing public concern over the ethical treatment of animals in research, we felt it incumbent upon us to include this general preface to these volumes in order to indicate why we think further - search using animals is necessary and why animal models of psychiatric disorders, in particular, are so important. We recognize that animals should only be used when suitable alternatives are not available. We think it self-e- dent, however, that humans can only be experimented upon in severely proscribed circumstances and alternative pro- dures using cell or tissue culture are inadequate in any models requiring assessments of behavioral change or of complex in vivo processes. However, when the distress, discomfort, or pain to the animals outweighs the anticipated gains for human welfare, then the research is not ethical and should not be carried out. It is imperative that each individual researcher examine his/her own research from a critical moral standpoint - fore engaging in it, taking into consideration the animals’ welfare as well as the anticipated gains. Furthermore, once a decision to proceed with research is made, it is the researcher’s responsibility to ensure that the animals’ w- fare is of prime concern in terms of appropriate housing, feeding, and maximum reduction of any uncomfortable or distressing effects of the experimental conditions, and that these conditions undergo frequent formalized monitoring.
Psychiatric Disorders
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Author : Toru Uehara
language : en
Publisher: BoD – Books on Demand
Release Date : 2011-10-26
Psychiatric Disorders written by Toru Uehara and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-26 with Medical categories.
Due to their prevalence, pervasiveness and burden inflicted on men and women of today, psychiatric disorders are considered as one of the most important, sever and painful illnesses. This impairment of cognitive, emotional, or behavioural functioning is in some cases tragic. Aside from knowing the physical organic factors, such as infections, endocrinal illnesses or head injuries, the aetiology of psychiatric disorders has remained a mystery. However, recent advances in psychiatry and neuroscience have been successful in discovering subsequent pathophysiology and reaching associated bio-psycho-social factors. This book consists of recent trends and developments in psychiatry from all over the world, presented in the form of multifarious and comprehensive articles. The first two sections of the book are reserved for articles on schizophrenia and depression, two major illnesses present in this field. The third section of the book is reserved for addiction psychiatry, related not only to socio-cultural but also biological alterations. The last section of the book, titled Biological Neuropsychiatry, consists of three topics - updated molecular biology, fundamental neuroscience and clinical neuropsychiatric conditions. Doubtlessly, this book will be fruitful for future developments and collaboration in world psychiatry.
Animal Models Of Neurological Disease Ii
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Author : Alan A. Boulton
language : en
Publisher: Humana
Release Date : 1992-07-29
Animal Models Of Neurological Disease Ii written by Alan A. Boulton and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-07-29 with Medical categories.
to the Animal Models Volumes This and several other volumes in the Neuromethods series will describe a number of animal models of neuropsychiatric disorders. Because of increasing public concern over the ethical treatment of animals in research, we felt it incumbent upon us to include this general preface to these volumes in order to indicate why we think further - search using animals is necessary and why animal models of psychiatric disorders, in particular, are so important. We recognize that animals should only be used when suitable alternatives are not available. We think it self-e- dent, however, that humans can only be experimented upon in severely proscribed circumstances and alternative pro- dures using cell or tissue culture are inadequate in any models requiring assessments of behavioral change or of complex in vivo processes. However, when the distress, discomfort, or pain to the animals outweighs the anticipated gains for human welfare, then the research is not ethical and should not be carried out. It is imperative that each individual researcher examine his/her own research from a critical moral standpoint - fore engaging in it, taking into consideration the animals’ welfare as well as the anticipated gains. Furthermore, once a decision to proceed with research is made, it is the researcher’s responsibility to ensure that the animals’ w- fare is of prime concern in terms of appropriate housing, feeding, and maximum reduction of any uncomfortable or distressing effects of the experimental conditions, and that these conditions undergo frequent formalized monitoring.
Psychiatric Disorders
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Author : Firas H. Kobeissy
language : en
Publisher:
Release Date : 2019
Psychiatric Disorders written by Firas H. Kobeissy and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Electronic books categories.
This second edition volume expands on the previous edition with updates to chapters and new chapters discussing the latest research in neuropsychiatric diseases. The chapters in this book are organized into eleven sections and cover the diversity and utility of animal models of psychiatric disorders, their development, modeling, and pathophysiological and molecular profiles. Part One looks at experimental modeling of neuropsychiatric studies and the usefulness and need of animal models. Parts Two and Three focus on experimental models of neuropsychiatric illnesses, including self-injurious behavior, bipolar disorder, anxiety, and learning and decision-making testing. Parts Four and Five discuss animal models of substance abuse. Part Six describes protocols to examine animal models related to maladaptive eating habits and behaviors. Parts Seven and Eight cover neurodegenerative diseases stemming from natural causes (aging), abnormal genetic backgrounds, or those brought on by trauma. Part Nine talks about inflammatory and metabolic alteration profiles relevant to autism spectrum disorders and depression. Parts Ten and Eleven conclude the book with a discussion on genetics, epigenetics, and system biology in the field of psychiatric disorders. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Psychiatric Disorders: Methods and Protocols, Second Edition is a useful resource for graduates, postdoctoral workers, and established scientists working in the fields of behavioral and molecular neuropsychiatric research. .
Animal Models For Psychiatry
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Author : J. D. Keehn
language : en
Publisher: Routledge
Release Date : 2018-02-19
Animal Models For Psychiatry written by J. D. Keehn and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-19 with Psychology categories.
Originally published in 1986, in this work Professor Keehn assesses the contributions of experimental psychology and ethology to psychiatric theory and practice at the time. He discusses the status of animals in psychopathology, and describes a number of animal clinical pictures, covering both abnormal movements and convulsions, and spontaneous behavioural disorders. He also includes animal models of such psychiatric illnesses as neurosis, psychosis, drug addiction and disorders of childhood, and examines the nature of mental illness and the status of psychiatric diagnosis. The book includes an evaluation of the ethics of experimental research with animals and a summary of humane experimental procedures. Animal Models for Psychiatry will be of special interest to psychiatrists, clinical and physiological psychologists, behavioural pharmacologists, and to veterinarians.